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Die Excimer-Laser-Trabekulotomie (ELT) stellt einen solchen minimal-invasiven Ansatz dar und kann mit einer Kataraktoperation kombiniert werden.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Ziel der Arbeit<\/jats:title>\n            <jats:p>\u00dcber 12\u00a0Monate wurden die Senkung des intraokularen Drucks (IOD), die Menge der drucksenkenden Lokaltherapie und das Auftreten unerw\u00fcnschter Ereignisse mit dem neuen Elios<jats:sup>TM<\/jats:sup>-Verfahren (Elios Vision GmbH, Germering, Deutschland)  anhand von Real-Life-Daten einer heterogenen Patientenpopulation, die eine ELT in Kombination mit einer Kataraktoperation (Phako-ELT) erhielt, analysiert.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Material und Methoden<\/jats:title>\n            <jats:p>Es wurden 20\u00a0Augen von 13\u00a0Patienten, die eine Phako-ELT erhalten haben, retrospektiv analysiert. Nach einer Standardphakoemulsifikation mit Hinterkammerlinsenimplantation wurden mit dem Excimer-Laser 10\u00a0Mikrokan\u00e4le angelegt. Die Patienten wurden \u00fcber 12\u00a0Monate nachbeobachtet und der IOD, die drucksenkende Lokaltherapie und das Auftreten unerw\u00fcnschter Ereignisse untersucht.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Ergebnisse<\/jats:title>\n            <jats:p>Das Durchschnittsalter lag bei 65\u00a0Jahren. Pr\u00e4operativ betrug der IOD\u00a017,5 (\u00b1\u202f5,3) mm\u202fHg. Die IOD-Senkung lag im Mittel bei 4,8\u202fmm\u202fHg (27,4\u202f%, <jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) am ersten postoperativen Tag, 3,2\u202fmm\u202fHg (18,3\u202f%, <jats:italic>p<\/jats:italic>\u202f=\u20090,22) nach 6\u00a0Monaten und 2,5\u202fmm\u202fHg (14,3\u202f%, <jats:italic>p<\/jats:italic>\u202f=\u20090,14) nach 12\u00a0Monaten. Die Drucksenker konnten von im Durchschnitt\u00a03,2 (\u00b1\u202f1,3) Wirkstoffen pr\u00e4operativ auf\u00a00,5 (\u00b1\u202f0,9) an Tag\u00a01 (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001), 1,9\u00a0(\u00b1\u202f1,2) nach 6\u00a0Monaten (<jats:italic>p<\/jats:italic>\u202f=\u20090,008) und 2,2\u00a0(\u00b1\u202f1,3) nach 12\u00a0Monaten (<jats:italic>p<\/jats:italic>\u202f=\u20090,013) reduziert werden.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Diskussion<\/jats:title>\n            <jats:p>In der hier untersuchten Kohorte ist die ELT in Kombination mit einer Kataraktoperation ein sicheres, minimal-invasives glaukomchirurgisches Verfahren, welches bei Patienten mit niedrigem Ausgangsdruck 1\u00a0Jahr postoperativ noch eine IOD-Senkung von 14,3\u202f% aufweist, bei einer Reduktion der drucksenkenden Medikation um 1\u00a0Wirkstoff. Da bei der ELT kein Implantat zum Einsatz kommt und die Bindehaut unangetastet bleibt, sind Folgeeingriffe nicht beeintr\u00e4chtigt und auch Filterkissenoperationen ohne Weiteres m\u00f6glich.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00347-024-02126-1","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T21:01:37Z","timestamp":1729112497000},"page":"46-51","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Wirksamkeit und Sicherheit der neuen Generation der Excimer-Laser-Trabekulotomie bei einer heterogenen Patientenpopulation\u00a0\u2013 1-Jahres-Follow-up","Efficacy and safety of the new generation of excimer laser trabeculotomy in a\u00a0heterogeneous patient population\u20141-year follow-up"],"prefix":"10.1007","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0071-1270","authenticated-orcid":false,"given":"Stefanie","family":"Gniesmer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svenja Rebecca","family":"Sonntag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swaantje","family":"Grisanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,16]]},"reference":[{"issue":"4","key":"2126_CR1","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1038\/eye.2009.172","volume":"24","author":"S Babighian","year":"2010","unstructured":"Babighian\u00a0S, Caretti\u00a0L, Tavolato\u00a0M et\u00a0al (2010) Excimer laser trabeculotomy vs 180 degrees selective laser trabeculoplasty in primary open-angle glaucoma. 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