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Von 2014 bis 2021 wurden Behandlungsdaten pr\u00e4operativ sowie postoperativ nach 6 bis 8\u00a0Wochen, nach erster (18\u202f\u00b1\u20093\u00a0Monate) und vollst\u00e4ndiger Fadenentfernung (31\u202f\u00b1\u20096\u00a0Monate) erhoben. Analysiert wurden Visus, IOD und Pentacam\u00ae HR-Messungen (OCULUS GmbH, Wetzlar, Deutschland) mit zentraler und peripherer Pachymetrie (CCT, PCT), Kammerwinkel (KW), Vorderkammertiefe (VKT) und -volumen (VKV).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Ergebnisse<\/jats:title>\n            <jats:p>Die Vorderkammergeometrie aller Augen \u00e4nderte sich nach PKP signifikant: fr\u00fchpostoperativ (6 bis 8\u00a0Wochen) stieg die Pachymetrie an (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001), KW, VKT und VKV (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) verringerten sich. Mit steigendem IOD (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) korrelierten CCT positiv und VKT negativ. In PKPs \u00e0\u00a0chaud waren im Gegensatz zu elektiven PKPs eine Verringerung der VKT und VKV (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) mit Zunahme der PCT (nasal <jats:italic>p<\/jats:italic>\u202f&lt;\u20090,033, temporal <jats:italic>p<\/jats:italic>\u202f=\u20090,042) signifikant. Bez\u00fcglich IOD, CCT und KW ergab sich dagegen kein signifikanter Unterschied. IOD-Erh\u00f6hungen \u2265\u202f25\u202fmm\u202fHg (<jats:italic>n<\/jats:italic>\u202f=\u200921) traten haupts\u00e4chlich in Keratokonusaugen (<jats:italic>n<\/jats:italic>\u202f=\u200914) auf, wobei ein hoher Anteil dieser F\u00e4lle eine Steroidresponse zeigte (<jats:italic>n<\/jats:italic>\u202f=\u200910).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Schlussfolgerung<\/jats:title>\n            <jats:p>Nach PKP ver\u00e4ndert sich postoperativ die Vorderkammergeometrie. Vorderkammerver\u00e4nderungen korrelieren aber nicht unbedingt mit einem IOD-Anstieg. M\u00f6glicherweise hat eine Steroidresponse einen gr\u00f6\u00dferen Einfluss auf postoperative Augeninnendruckanstiege, weil bei Keratokonusaugen postoperativ keine signifikante Vorderkammerabflachung auftrat. In zuk\u00fcnftigen prospektiven Studien ist zu erwarten, dass im komplexen System der Regulation des postoperativen IOD weitere Faktoren mit potenziellem Einfluss identifiziert werden.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00347-025-02225-7","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T18:54:58Z","timestamp":1744224898000},"page":"460-469","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Einfluss der Vorderkammergeometrie auf den intraokularen Druckanstieg nach perforierender Keratoplastik\u00a0\u2013 Vergleich zwischen elektiven und\u00a0Eingriffen \u00e0\u00a0chaud","Impact of anterior chamber geometry on intraocular pressure rise after penetrating keratoplasty\u00a0\u2013 Comparison between elective and emergency procedures"],"prefix":"10.1007","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2685-7609","authenticated-orcid":false,"given":"Roberta","family":"Schir\u00f2","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Munteanu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loay","family":"Daas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"L\u00f6w","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,9]]},"reference":[{"key":"2225_CR1","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1097\/ICO.0000000000003035","volume":"42","author":"T Berger","year":"2023","unstructured":"Berger\u00a0T, Seitz\u00a0B, Flockerzi\u00a0E, Suffo\u00a0S, Daas\u00a0L (2023) Indications and Results of Emergency Penetrating Keratoplasty With Simultaneous Cataract Surgery (\u201cTriple-PKP \u00e0\u00a0Chaud\u201d). 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}