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Sie wird \u2013\u00a0\u00e4hnlich der Akantham\u00f6benkeratitis\u00a0\u2013 oft initial an der Spaltlampe fehldiagnostiziert. Seit mehr als 20\u00a0Jahren ist eine H\u00e4ufigkeitszunahme der Pilzkeratitis auch in Deutschland festzustellen, m\u00f6glicherweise bedingt durch die vermehrte Verwendung von weichen Kontaktlinsen und den Klimawandel. Dieser Beitrag gibt einen \u00dcberblick \u00fcber die typischen klinischen Zeichen und Symptome der Keratomykose und stellt neueste Erkenntnisse im Bereich der Diagnostik sowie der medikament\u00f6sen und insbesondere der mikrochirurgischen Therapie dar. Ein spezieller Fokus wird hierbei auf die Indikationsstellung und Technik der Notfallkeratoplastik (\u00e0\u00a0chaud) bei Pilzkeratitis sowie deren Nachsorge gelegt.<\/jats:p>","DOI":"10.1007\/s00347-025-02274-y","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T14:31:26Z","timestamp":1753367486000},"page":"652-669","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pilzkeratitis in Deutschland","Fungal keratitis in Germany"],"prefix":"10.1007","volume":"122","author":[{"given":"Berthold","family":"Seitz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Abu Dail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Suffo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Flockerzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Flockerzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Daas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"2274_CR1","doi-asserted-by":"publisher","first-page":"e49","DOI":"10.1016\/S1473-3099(20)30448-5","volume":"21","author":"L Brown","year":"2021","unstructured":"Brown\u00a0L, Leck\u00a0AK, Gichangi\u00a0M, Burton\u00a0MJ, Denning\u00a0DW (2021) The global incidence and diagnosis of fungal keratitis. 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Eye 23:1308\u20131313","journal-title":"Eye"}],"container-title":["Die Ophthalmologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-025-02274-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00347-025-02274-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-025-02274-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T17:02:00Z","timestamp":1769533320000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00347-025-02274-y"}},"subtitle":["Diagnostik, konservative und mikrochirurgische Therapie","Diagnostics, conservative and microsurgical treatment"],"short-title":[],"issued":{"date-parts":[[2025,7,24]]},"references-count":86,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["2274"],"URL":"https:\/\/doi.org\/10.1007\/s00347-025-02274-y","relation":{"has-translation":[{"id-type":"doi","id":"10.1007\/s00347-025-02371-y","asserted-by":"subject"},{"id-type":"doi","id":"10.1007\/s00347-025-02371-y","asserted-by":"object"}]},"ISSN":["2731-720X","2731-7218"],"issn-type":[{"value":"2731-720X","type":"print"},{"value":"2731-7218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,24]]},"assertion":[{"value":"10 June 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und Wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"B.\u00a0Seitz\n                      : A.\u00a0Finanzielle Interessen: Forum Oculus Spezial in Frankfurt, 21.05.2022 (Fa. Bayer, Geldleistung). \u2013\u00a0B. Nichtfinanzielle Interessen: Direktor der Klinik f\u00fcr Augenheilkunde am Universit\u00e4tsklinikum des Saarlandes in Homburg\/Saar | Mitgliedschaften: Deutsche Ophthalmologische Gesellschaft (DOG) seit 1989; The Association for Research in Vision and Ophthalmology (ARVO) seit 1991; Berufsverband der Augen\u00e4rzte Deutschlands e.\u202fV. (BVA) seit 1992; American Academy of Ophthalmology (AAO) seit 1997; Deutsche Transplantationsgesellschaft (DTG) seit 1998; European Association for Vision and Eye Research (EVER) seit 1998; Arbeitsgemeinschaft Deutscher Hornhautbanken seit 2000; Gr\u00fcndungsmitglied und Sprecher der Sektion Kornea in der DOG seit 2000; International Society of Dacryology and Dry Eye (ISD&DE) seit 2003; European Eye Bank Association (EEBA) seit 2003; The Cornea Society seit 2004; European Society of Cataract and Refractive Surgeons (ESCRS) seit 2008; Mitglied der Nationalen Akademie der Wissenschaften Leopoldina seit 08\/2011; Deutsches Komitee zur Verh\u00fctung von Blindheit DKVB seit 03\/2016; EuCornea seit 06\/2019; Stellv. Vorsitzender der Intl. Ophthalmological Fellowship Foundation e.\u202fV. (IOFF) seit 10\/2020; Director of IOFF-Subspecialty Fellowships seit 10\/2020; Board Member der Ophthalmology Foundation (OF) seit 12\/2020; Mitglied des Herausgeberboards von\n                      Die Ophthalmologie\n                      ; Mitglied des Guideline and Consensus Sub-Committee der Intl. Keratoconus Society, seit 04\/2023; Mitglied der Academia Ophthalmologica Internationalis (AOI) seit 03\/2024.\n                      Y.\u00a0Abu Dail\n                      : A.\u00a0Finanzielle Interessen: Y.\u00a0Abu Dail gibt an, dass kein finanzieller Interessenkonflikt besteht.\u00a0\u2013 B. Nichtfinanzielle Interessen: Assistenzarzt f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum des Saarlandes | Mitgliedschaft: Deutsche Ophthalmologische Gesellschaft.\n                      T.\u00a0Berger\n                      : A.\u00a0Finanzielle Interessen: T.\u00a0Berger gibt an, dass kein finanzieller Interessenkonflikt besteht. \u2013\u00a0B. Nichtfinanzielle Interessen: Oberarzt an der Klinik f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum des Saarlandes, Homburg\/Saar.\n                      S.\u00a0Suffo\n                      : A.\u00a0Finanzielle Interessen: S.\u00a0Suffo gibt an, dass kein finanzieller Interessenkonflikt besteht.\u00a0\u2013 B. Nichtfinanzielle Interessen: Angestellter Oberarzt in der Augenklinik des Universit\u00e4tsklinikums des Saarlandes | Mitgliedschaft: Deutsche Ophthalmologische Gesellschaft (DOG).\n                      E.\u00a0Flockerzi\n                      : A.\u00a0Finanzielle Interessen: E.\u00a0Flockerzi gibt an, dass kein finanzieller Interessenkonflikt besteht. \u2013\u00a0B. Nichtfinanzielle Interessen:\u00a0\u2013 Oberarzt an der Klinik f\u00fcr Augenheilkunde am Universit\u00e4tsklinikum des Saarlandes UKS | Mitgliedschaften: DOG, BVA.\n                      F.\u00a0Flockerzi\n                      : A.\u00a0Finanzielle Interessen: F.\u00a0Flockerzi gibt an, dass kein finanzieller Interessenkonflikt besteht. \u2013\u00a0B. Nichtfinanzielle Interessen: Angestellter Pathologe, Institut f\u00fcr Pathologie, UKS Homburg, Oberarzt | Mitgliedschaften: Deutsche Gesellschaft f\u00fcr Pathologie, Bundesverband deutscher Pathologen.\n                      L.\u00a0Daas\n                      : A.\u00a0Finanzielle Interessen: L.\u00a0Daas gibt an, dass kein finanzieller Interessenkonflikt besteht.\u00a0\u2013 B. Nichtfinanzielle Interessen: Leitender Oberarzt im Angestelltenverh\u00e4ltnis an der Universit\u00e4ts-Augenklinik des Saarlandes in Homburg\/Saar | Mitgliedschaften: DOG\/DOC.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der Wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf\n                      \n                      .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}