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F\u00fcr Menschen mit einer psychischen Erkrankung wird untersucht, inwiefern sich das Krankheits- und Therapieerleben unterscheidet gegen\u00fcber Menschen ohne psychische Komorbidit\u00e4t.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodik<\/jats:title>\n                    <jats:p>Im Hamburg Register f\u00fcr intravitreale Injektionen wurden Umfragen zum Erleben der Erkrankung und der Therapie an 2\u00a0Augenkliniken durchgef\u00fchrt. Psychische Komorbidit\u00e4t wurde durch folgende Angaben erfasst: Vorhandensein psychischer Erkrankungen, einem Generalized-Anxiety-Disorder-Scale-Wert von \u2265\u202f3, Empfinden m\u00e4\u00dfiger-extremer Angst\/Niedergeschlagenheit. Zur Bewertung des Krankheitserlebens stuften die Patienten die Beeintr\u00e4chtigung der Lebensqualit\u00e4t durch die Augenerkrankung anhand von 6\u00a0Stufen ein. Ihr Therapieerleben bewerteten Patienten anhand von Skalen (0\u201310) zur Intensit\u00e4t der Angst, k\u00f6rperlichen Anspannung und Schmerzen bei der letzten Injektion. Gruppenunterschiede wurden anhand des mittleren Visus und mittels linearer Regression mit Alter und Geschlecht als Kofaktoren analysiert.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>\n                      Psychische Erkrankungen wiesen 14,5\u202f% der Patienten auf. Bei vergleichbarem mittlerem Visus empfanden 27,1\u202f% der psychisch Erkrankten eine sehr starke Beeintr\u00e4chtigung der Lebensqualit\u00e4t (vs.\u00a011,2\u202f% in der Gruppe der Nicht-Erkrankten). Psychisch erkrankte Patienten gaben h\u00f6here mittlere Werte f\u00fcr Angst (+1,5\u00a0Punkte; KI 0,76\u20132,16,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&lt;\u20090,001) und k\u00f6rperliche Anspannung an (+1,2\u00a0Punkte; KI 0,5\u20131,9,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&lt;\u20090,001). Die Schmerzintensit\u00e4t war mit +0,61\u00a0Punkten nicht signifikant h\u00f6her (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u20090,058).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diskussion<\/jats:title>\n                    <jats:p>Patienten mit psychischer Komorbidit\u00e4t erleben ihre Krankheit und die IVOM-Therapie negativer als psychisch Gesunde. Es ist daher sinnvoll, die besonderen Belange psychisch belasteter Menschen in der Gestaltung der IVOM-Therapie zu ber\u00fccksichtigen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphic abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s00347-025-02348-x","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T10:35:25Z","timestamp":1764930925000},"page":"133-139","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychische Komorbidit\u00e4ten bei IVOM(intravitreale operative Medikamentenapplikation)-Patienten","Mental comorbidities among patients receiving intravitreal operative drug injections"],"prefix":"10.1007","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9028-913X","authenticated-orcid":false,"given":"Tina","family":"Pfeffer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin S.","family":"Spitzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Schargus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Wolfram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"2348_CR1","doi-asserted-by":"publisher","first-page":"238146831879936","DOI":"10.1177\/2381468318799361","volume":"3","author":"F Al Sayah","year":"2018","unstructured":"Al Sayah\u00a0F, Ohinmaa\u00a0A, Johnson\u00a0JA (2018) Screening for Anxiety and Depressive Symptoms in Type\u00a02 Diabetes Using Patient-Reported Outcome Measures: Comparative Performance of the EQ-5D-5L and SF-12v2. 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