{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T04:31:43Z","timestamp":1789965103612,"version":"4.0.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00347-025-02350-3","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T13:34:44Z","timestamp":1764164084000},"page":"307-310","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Transiente Makulopathie nach intrakameraler Cefuroxim-Injektion","Transient maculopathy after intracameral injection of cefuroxime"],"prefix":"10.1007","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9160-4381","authenticated-orcid":false,"given":"Juliane","family":"Klon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitja Alexander","family":"Heinrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laszlo","family":"Kiraly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"issue":"3","key":"2350_CR1","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.jcrs.2006.02.014","volume":"32","author":"DV Seal","year":"2006","unstructured":"Seal\u00a0DV, Barry\u00a0P, Gettinby\u00a0G et\u00a0al (2006) ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a\u00a0European multicenter study. J\u00a0Cataract Refract Surg 32(3):396\u2013406","journal-title":"J Cataract Refract Surg"},{"key":"2350_CR2","unstructured":"https:\/\/www.escrs.org\/escrs-guideline-for-cataract-surgery. Zugegriffen: 12. Juli 2025"},{"issue":"1","key":"2350_CR3","doi-asserted-by":"publisher","first-page":"P1","DOI":"10.1016\/j.ophtha.2021.10.006","volume":"129","author":"KM Miller","year":"2022","unstructured":"Miller\u00a0KM, Oetting\u00a0TA, Tweeten\u00a0JP et\u00a0al (2022) Cataract in the Adult Eye Preferred Practice Pattern. Ophthalmology 129(1):P1\u2013P126","journal-title":"Ophthalmology"},{"key":"2350_CR4","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/j.jcrs.0000000000000757","volume":"48","author":"DF Chang","year":"2022","unstructured":"Chang\u00a0DF, Rhee\u00a0DJ (2022) Antibiotic prophylaxis of postoperative endophthalmitis following cataract surgery: results of the 2021 ASCRS member survey. J\u00a0Cataract Refract Surg 48:3\u20137","journal-title":"J Cataract Refract Surg"},{"issue":"10","key":"2350_CR5","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1097\/j.jcrs.0000000000001237","volume":"49","author":"WG Myers","year":"2023","unstructured":"Myers\u00a0WG, Chang\u00a0DF, Shorstein\u00a0NH et\u00a0al (2023) ASCRS clinical advisory on intracameral moxifloxacin injection for infection prophylaxis. J\u00a0Cataract Refract Surg 49(10):1068\u20131070","journal-title":"J Cataract Refract Surg"},{"issue":"9","key":"2350_CR6","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1136\/bjophthalmol-2017-311051","volume":"102","author":"RC Bowen","year":"2018","unstructured":"Bowen\u00a0RC, Zhou\u00a0AX, Bondalapati\u00a0S et\u00a0al (2018) Comparative analysis of the safety and efficacy of intracameral cefuroxime, moxifloxacin and vancomycin at the end of cataract surger: a\u00a0meta-analysis. Br J Ophthalmol 102(9):1268\u20131276","journal-title":"Br J Ophthalmol"},{"issue":"21","key":"2350_CR7","first-page":"00032","volume":"6691","author":"L D\u00edez-\u00c1lvarez","year":"2021","unstructured":"D\u00edez-\u00c1lvarez\u00a0L, Salv\u00e1-Palomeque\u00a0T, Jaumandreu\u00a0L et\u00a0al (2021) Ocular toxicity after inadvertent overdose of intracameral cefuroxime during cataract surgery. Toxicidad ocular tras sobredosificaci\u00f3n accidental de cefuroxima intracameral en cirug\u00eda de catarata. Arch Soc Esp Oftalmol 6691(21):32\u201330","journal-title":"Arch Soc Esp Oftalmol"},{"issue":"2","key":"2350_CR8","doi-asserted-by":"publisher","first-page":"e153","DOI":"10.1111\/j.1755-3768.2010.02103.x","volume":"90","author":"P Olavi","year":"2012","unstructured":"Olavi\u00a0P (2012) Ocular toxicity in cataract surgery because of inaccurate preparation and erroneous use of 50\u202fmg\/ml intracameral cefuroxime. Acta Ophthalmol 90(2):e153\u2013e154","journal-title":"Acta Ophthalmol"},{"issue":"2","key":"2350_CR9","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.jcrs.2010.08.047","volume":"37","author":"MN Delyfer","year":"2011","unstructured":"Delyfer\u00a0MN, Rougier\u00a0MB, Leoni\u00a0S et\u00a0al (2011) Ocular toxicity after intracameral injection of very high doses of cefuroxime during cataract surgery. J\u00a0Cataract Refract Surg 37(2):271\u2013278","journal-title":"J Cataract Refract Surg"},{"key":"2350_CR10","doi-asserted-by":"publisher","first-page":"493","DOI":"10.2147\/OPTH.S74249","volume":"9","author":"B \u00c7ak\u0131r","year":"2015","unstructured":"\u00c7ak\u0131r\u00a0B, Celik\u00a0E, Aksoy\u00a0N\u00d6 et\u00a0al (2015) Toxic anterior segment syndrome after uncomplicated cataract surgery possibly associated with intracamaral use of cefuroxime. Clin Ophthalmol 9:493\u2013497","journal-title":"Clin Ophthalmol"},{"key":"2350_CR11","doi-asserted-by":"publisher","first-page":"101343","DOI":"10.1016\/j.ajoc.2022.101343","volume":"25","author":"JY Ku","year":"2022","unstructured":"Ku\u00a0JY, Wong\u00a0SW, Steeples\u00a0LR et\u00a0al (2022) High dose cefuroxime causing retinal toxicity in a\u00a0patient undergoing trabeculectomy. Am J Ophthalmol Case Rep 25:101343","journal-title":"Am J Ophthalmol Case Rep"},{"issue":"1","key":"2350_CR12","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.jcrs.2017.09.031","volume":"44","author":"C Zuo","year":"2018","unstructured":"Zuo\u00a0C, Mi\u00a0L, Ye\u00a0D et\u00a0al (2018) Toxic retinopathy after phacoemulsification when the cefuroxime dilution is correct. J\u00a0Cataract Refract Surg 44(1):28\u201333","journal-title":"J Cataract Refract Surg"},{"issue":"6","key":"2350_CR13","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1007\/s40123-025-01137-8","volume":"14","author":"A Cusumano","year":"2025","unstructured":"Cusumano\u00a0A, Pileri\u00a0MA, Falsini\u00a0B et\u00a0al (2025) Structural and Functional Insight into Intracameral Cefuroxime Ocular Toxic Syndrome (ICOTS) in Eyes with Disrupted Intraocular Barrier. Ophthalmol Ther 14(6):1337\u20131347","journal-title":"Ophthalmol Ther"},{"issue":"1","key":"2350_CR14","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1159\/000526449","volume":"66","author":"J Sun","year":"2023","unstructured":"Sun\u00a0J, Wei\u00a0Y, Li\u00a0H, Zheng\u00a0S, Wu\u00a0X (2023) Macular Toxicity of Low-Concentration Cefuroxime during Cataract Surgery in Vitrectomized Eyes. Ophthalmic Res 66(1):116\u2013123","journal-title":"Ophthalmic Res"},{"issue":"1","key":"2350_CR15","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s10633-014-9465-7","volume":"130","author":"C Faure","year":"2015","unstructured":"Faure\u00a0C, Perreira\u00a0D, Audo\u00a0I (2015) Retinal toxicity after intracameral use of a\u00a0standard dose of cefuroxime during cataract surgery. Doc Ophthalmol 130(1):57\u201363","journal-title":"Doc Ophthalmol"},{"key":"2350_CR16","unstructured":"https:\/\/www.bfarm.de\/SharedDocs\/Downloads\/DE\/Arzneimittel\/Pharmakovigilanz\/PSUSAS\/a-f\/cefuroxim-natrium_cmdh.pdf?__blob=publicationFile. Zugegriffen: 26. Juni 2025"},{"issue":"12","key":"2350_CR17","doi-asserted-by":"publisher","first-page":"2139","DOI":"10.1016\/j.jcrs.2008.08.022","volume":"34","author":"E Yoeruek","year":"2008","unstructured":"Yoeruek\u00a0E, Spitzer\u00a0MS, Saygili\u00a0O et\u00a0al (2008) Comparison of in vitro safety profiles of vancomycin and cefuroxime on human corneal endothelial cells for intracameral use. J\u00a0Cataract Refract Surg 34(12):2139\u20132145","journal-title":"J Cataract Refract Surg"},{"issue":"5","key":"2350_CR18","doi-asserted-by":"publisher","first-page":"e141","DOI":"10.1016\/j.jcjo.2016.05.008","volume":"51","author":"M Aslankurt","year":"2016","unstructured":"Aslankurt\u00a0M, \u00c7eki\u00e7\u00a0O, And\u0131 \u0130 et\u00a0al (2016) Transient macular edema after standard dose of intracameral cefuroxime injection during phacoemulsification. Can J Ophthalmol 51(5):e141\u2013e142","journal-title":"Can J Ophthalmol"}],"container-title":["Die Ophthalmologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-025-02350-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00347-025-02350-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-025-02350-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T09:30:12Z","timestamp":1775640612000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00347-025-02350-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,26]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["2350"],"URL":"https:\/\/doi.org\/10.1007\/s00347-025-02350-3","relation":{},"ISSN":["2731-720X","2731-7218"],"issn-type":[{"value":"2731-720X","type":"print"},{"value":"2731-7218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,26]]},"assertion":[{"value":"21 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"J.\u00a0Klon, M.A.\u00a0Heinrich und L.\u00a0Kiraly geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}