{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:34:23Z","timestamp":1777869263553,"version":"3.51.4"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Universit\u00e4tsklinikum des Saarlandes und Medizinische Fakult\u00e4t der Universit\u00e4t des Saarlandes"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Ein 8\u2011j\u00e4hriger Junge stellte sich zur Mitbeurteilung einer stromalen kristallinen Hornhauttr\u00fcbung an beiden Augen mit zunehmender Photophobie vor. Die spaltlampenmikroskopische Untersuchung zeigte anterior-stromale, kristalline ringf\u00f6rmige Hornhautablagerungen bei ansonsten unauff\u00e4lligem Hornhautbefund an beiden Augen. Auf Grundlage dieser Befunde wurde die Diagnose einer juvenilen Form der Schnyder-Hornhautdystrophie gestellt. Der Patient wurde \u00fcber einen Zeitraum von 3\u00a0Jahren j\u00e4hrlich kontrolliert. Die Familienanamnese ergab eine bekannte Schnyder-Hornhautdystrophie bei der Gro\u00dfmutter des Patienten. Bei untypischen kristallinen, ringf\u00f6rmigen Hornhauttr\u00fcbungen im Kindesalter sollte differenzialdiagnostisch eine Schnyder-Hornhautdystrophie in Betracht gezogen werden. Es ist anzumerken, dass kristalline Ablagerungen nur in 50\u202f% aller Patienten mit dieser Hornhautdystrophie vorhanden sind. Die Diagnosestellung kann insbesondere bei jungen Patienten erschwert sein, da typische klinische Zeichen wie eine diskoide stromale Hornhauttr\u00fcbung oder ein Arcus lipoides h\u00e4ufig erst in der dritten Lebensdekade auftreten und fr\u00fche Befunde von Hornhautdystrophien im Kindesalter in der Literatur selten abgebildet werden. In dem hier beschriebenen Fall erleichterte die positive Familienanamnese die Diagnose. Eine Excimerlaser-assistierte phototherapeutische Keratektomie wurde als potenzielle Behandlungsoption diskutiert, jedoch von der Familie nicht gew\u00fcnscht.<\/jats:p>","DOI":"10.1007\/s00347-026-02410-2","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:00:28Z","timestamp":1772118028000},"page":"382-385","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beidseitige ringf\u00f6rmige stromale kristalline Hornhautablagerungen bei einem 8-j\u00e4hrigen Kind","Bilateral ring-shaped stromal crystalline corneal deposits in an 8-year-old child"],"prefix":"10.1007","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5266-0217","authenticated-orcid":false,"given":"Ilinca Teodora","family":"Mihai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian Norbert","family":"Fries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alb\u00e9ric","family":"Sneyers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"2410_CR1","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1007\/s00347-023-01919-0","volume":"120","author":"T Berger","year":"2023","unstructured":"Berger\u00a0T, Flockerzi\u00a0E, Daas\u00a0L, Hamon\u00a0L, Khattabi\u00a0Z, Berger\u00a0M, Seitz\u00a0B (2023) Moderne Hornhautdiagnostik als Schl\u00fcssel f\u00fcr die korrekte Einordnung der Erkrankung und optimale Therapieentscheidung. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}