{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:16:48Z","timestamp":1787930208287,"version":"build-2784847793"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Universit\u00e4tsklinikum Bonn"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Onkozytome des Augenlids sind seltene benigne epitheliale Tumoren und klinisch nicht zuverl\u00e4ssig von anderen benignen oder malignen Lidrandtumoren abzugrenzen. Diese Fallserie beschreibt drei Patienten im Alter von 64 bis 77 Jahren mit langsam progredienten, gut begrenzten, r\u00f6tlich-lividen L\u00e4sionen des Unterlids, davon zwei in peripunktaler Lokalisation. Histopathologisch zeigten sich scharf begrenzte epitheliale Tumoren aus polygonalen Onkozyten mit feingranul\u00e4rem, eosinophilem Zytoplasma und \u00fcberwiegend adenoider bzw. tubul\u00e4rer Architektur. Immunhistochemisch bestand eine Positivit\u00e4t der Tumorzellen f\u00fcr Zytokeratin 7 (CK7), ein niedriger Ki-67-Proliferationsindex sowie eine fokale Positivit\u00e4t myoepithelialer Zellanteile f\u00fcr \u03b1-Smooth-Muscle-Actin (SMA). Nach vollst\u00e4ndiger Exzision zeigte sich in einem Nachbeobachtungszeitraum von 10 bis 18 Monaten kein Rezidiv. Onkozytome sollten bei chronisch progredienten, r\u00f6tlich-lividen L\u00e4sionen des Lidrandes, insbesondere bei \u00e4lteren Patienten, differenzialdiagnostisch ber\u00fccksichtigt werden. Die histopathologische Sicherung ist entscheidend, da die vollst\u00e4ndige Exzision diagnostisch und in der Regel kurativ ist.<\/jats:p>","DOI":"10.1007\/s00347-026-02461-5","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T15:34:09Z","timestamp":1781019249000},"page":"733-737","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Onkozytom des Augenlids: Fallserie mit histopathologischer Korrelation","Oncocytoma of the eyelid: case series with histopathological correlation"],"prefix":"10.1007","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7978-3245","authenticated-orcid":false,"given":"Yannick N.","family":"Liermann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina C.","family":"Herwig-Carl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank G.","family":"Holz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin U.","family":"Loeffler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"2461_CR1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/2955030","volume":"2022","author":"F Almutairi","year":"2022","unstructured":"Almutairi\u00a0F, Alsamnan\u00a0M, Maktabi\u00a0A, Elkhamary\u00a0S, Alkatan\u00a0HM, AlOtaibi\u00a0H (2022) Recurrent Oncocytoma of the Lacrimal Sac. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}}]}}