{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T16:49:27Z","timestamp":1789836567979,"version":"4.0.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T00:00:00Z","timestamp":1455235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100007136","name":"Secretar\u00eda de Estado de Investigaci\u00f3n, Desarrollo e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["AGL2013-46448-C3-1R"],"award-info":[{"award-number":["AGL2013-46448-C3-1R"]}],"id":[{"id":"10.13039\/501100007136","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002848","name":"Comisi\u00f3n Nacional de Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["FONDECYT 11121498"],"award-info":[{"award-number":["FONDECYT 11121498"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Comp Physiol B"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s00360-016-0966-4","type":"journal-article","created":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T07:29:12Z","timestamp":1455262152000},"page":"471-484","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Characterization of melatonin synthesis in the gastrointestinal tract of rainbow trout (Oncorhynchus mykiss): distribution, relation with serotonin, daily rhythms and photoperiod regulation"],"prefix":"10.1007","volume":"186","author":[{"given":"Jos\u00e9 L.","family":"Mu\u00f1oz-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos A.","family":"L\u00f3pez-Pati\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"\u00c1lvarez-Otero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Gesto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 L.","family":"Soengas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas M.","family":"M\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,2,12]]},"reference":[{"key":"966_CR1","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/BF00226505","volume":"254","author":"C Anderson","year":"1988","unstructured":"Anderson C, Campbell G (1988) Immunohistochemical study of 5-HT-containing neurons in the teleost intestine: relation to the presence of enterochromaffin cells. Cell Tissue Res 254:553\u2013559","journal-title":"Cell Tissue Res"},{"key":"966_CR2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0006-8993(03)02297-2","volume":"969","author":"MJ Bayarri","year":"2003","unstructured":"Bayarri MJ, Rol De Lama MA, Madrid JA, S\u00e1nchez-V\u00e1zquez FJ (2003) Both pineal and lateral eyes are needed to sustain daily circulating melatonin rhythms in the sea bass. Brain Res 969:175\u2013182","journal-title":"Brain Res"},{"key":"966_CR3","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1210\/endo.139.3.5790","volume":"139","author":"V B\u00e9gay","year":"1998","unstructured":"B\u00e9gay V, Falc\u00f3n J, Cahill GM, Klein DC, Coon SL (1998) Transcripts encoding two melatonin synthesis enzymes in the teleost pineal organ: circadian regulation in pike and zebrafish, but not in trout. Endocrinology 139:905\u2013912","journal-title":"Endocrinology"},{"key":"966_CR4","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.exer.2005.08.025","volume":"82","author":"L Besseau","year":"2006","unstructured":"Besseau L, Benyassi A, M\u00f8ller M, Coon SL, Weller JL, Boeuf G, Klein DC, Falc\u00f3n J (2006) Melatonin pathway: breaking the \u201chigh-at-night\u201d rule in trout retina. Exp Eye Res 82:620\u2013627","journal-title":"Exp Eye Res"},{"key":"966_CR5","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1159\/000179137","volume":"12","author":"GA Bubenik","year":"1980","unstructured":"Bubenik GA (1980) Localization of melatonin in the digestive tract of the rat. Effect of maturation, diurnal variation, melatonin treatment and pinealectomy. Hormone Res 12:313\u2013323","journal-title":"Hormone Res"},{"key":"966_CR6","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1023\/A:1020107915919","volume":"47","author":"GA Bubenik","year":"2002","unstructured":"Bubenik GA (2002) Gastrointestinal melatonin. Localization, function and clinical relevance. Dig Dis Sci 47:2336\u20132348","journal-title":"Dig Dis Sci"},{"key":"966_CR7","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1159\/000109107","volume":"6","author":"GA Bubenik","year":"1997","unstructured":"Bubenik GA, Brown GM (1997) Pinealectomy reduces melatonin levels in the serum but not in the gastrointestinal tract of rats. Biol Signals 6:40\u201344","journal-title":"Biol Signals"},{"key":"966_CR8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1600-079X.1994.tb00088.x","volume":"16","author":"GA Bubenik","year":"1994","unstructured":"Bubenik GA, Pang SF (1994) The role of serotonin and melatonin in gastrointestinal physiology: ontogeny, regulation of food intake and mutual serotonin-melatonin feedback. J Pineal Res 16:91\u201399","journal-title":"J Pineal Res"},{"key":"966_CR9","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1006\/gcen.1997.6889","volume":"106","author":"GA Bubenik","year":"1997","unstructured":"Bubenik GA, Pang SF (1997) Melatonin levels in the gastrointestinal tissues of fish, amphibians, and a reptile. Gen Comp Endocrinol 106:415\u2013419","journal-title":"Gen Comp Endocrinol"},{"key":"966_CR10","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1600-079X.1996.tb00294.x","volume":"21","author":"GA Bubenik","year":"1996","unstructured":"Bubenik GA, Pang SF, Hacker RR, Smith PS (1996) Melatonin concentrations in serum and tissues of porcine gastrointestinal tract and their relationship to the intake and passage of food. J Pineal Res 21:251\u2013256","journal-title":"J Pineal Res"},{"key":"966_CR11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1600-079X.1999.tb00567.x","volume":"26","author":"GA Bubenik","year":"1999","unstructured":"Bubenik GA, Hacker RR, Brown GM, Baros L (1999) Melatonin concentrations in the luminal fluid, mucosa and muscularis of the bovine and porcine gastrointestinal tract. J Pineal Res 26:56\u201363","journal-title":"J Pineal Res"},{"key":"966_CR12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1034\/j.1600-079x.2000.280102.x","volume":"28","author":"GA Bubenik","year":"2000","unstructured":"Bubenik GA, Pang SF, Cockshut JR, Smith PS, Grovum LW, Friendship RM, Hacker RR (2000) Circadian variation of portal, arterial and venous blood levels of melatonin in pigs and its relationship to food intake and sleep. J Pineal Res 28:9\u201315","journal-title":"J Pineal Res"},{"key":"966_CR13","first-page":"245","volume":"145","author":"RI Caama\u00f1o-Tub\u00edo","year":"2007","unstructured":"Caama\u00f1o-Tub\u00edo RI, P\u00e9rez J, Ferreiro S, Aldegunde M (2007) Peripheral serotonin dynamics in the rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol Part C 145:245\u2013255","journal-title":"Comp Biochem Physiol Part C"},{"key":"966_CR14","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ygcen.2005.04.010","volume":"144","author":"RM Ceinos","year":"2005","unstructured":"Ceinos RM, Rabade S, Soengas JL, Miguez JM (2005) Indoleamines and 5-methoxyindoles in trout pineal organ in vivo: daily changes and influence of photoperiod. Gen Comp Endocrinol 144:67\u201377","journal-title":"Gen Comp Endocrinol"},{"key":"966_CR15","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ygcen.2008.01.003","volume":"156","author":"RM Ceinos","year":"2008","unstructured":"Ceinos RM, Polakof S, Rodr\u00edguez A, Soengas JL, M\u00edguez JM (2008) Food deprivation and refeeding effects on pineal \u00edndoles metabolism and melatonin synthesis in the rainbow trout Oncorhynchus mykiss. Gen Comp Endocrinol 156:410\u2013417","journal-title":"Gen Comp Endocrinol"},{"key":"966_CR16","doi-asserted-by":"crossref","first-page":"3888","DOI":"10.3748\/wjg.v17.i34.3888","volume":"14","author":"CQ Chen","year":"2011","unstructured":"Chen CQ, Fichna J, Bashashati M, Li YY, Storr M (2011) Distribution, function and physiological role of melatonin in the lower gut. World J Gastroenterol 14:3888\u20133898","journal-title":"World J Gastroenterol"},{"key":"966_CR17","doi-asserted-by":"crossref","first-page":"9076","DOI":"10.1074\/jbc.274.13.9076","volume":"274","author":"SL Coon","year":"1999","unstructured":"Coon SL, B\u00e9gay V, Deurloo D, Falc\u00f3n J, Klein DC (1999) Two arylalkylamine N-acetyltransferase genes mediate melatonin synthesis in fish. J Biol Chem 274:9076\u20139082","journal-title":"J Biol Chem"},{"key":"966_CR18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0301-0082(98)00078-1","volume":"58","author":"J Falc\u00f3n","year":"1999","unstructured":"Falc\u00f3n J (1999) Cellular circadian clocks in the pineal. Prog Neurobiol 58:121\u2013162","journal-title":"Prog Neurobiol"},{"key":"966_CR19","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/978-1-4615-3042-8_13","volume-title":"Rhythms in fishes, NATO ASI series A: life sciences","author":"J Falc\u00f3n","year":"1992","unstructured":"Falc\u00f3n J, Thibault C, B\u00e9gay V, Zackmann A, Collin JP (1992) Regulation of the rhythmic melatonin secretion by the fish pineal photoreceptor cells. In: Ali MA (ed) Rhythms in fishes, NATO ASI series A: life sciences, vol 236. Plenum Press, New York, pp 167\u2013198"},{"key":"966_CR20","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1046\/j.1365-2826.2003.00993.x","volume":"15","author":"J Falc\u00f3n","year":"2003","unstructured":"Falc\u00f3n J, Gothilf Y, Coon SL, Boeuf G, Klein DC (2003) Genetic, temporal and developmental differences between melatonin rhythm generating systems in the teleost fish pineal organ and retina. J Neuroendocrinol 15:378\u2013382","journal-title":"J Neuroendocrinol"},{"key":"966_CR21","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.ygcen.2009.04.026","volume":"165","author":"J Falc\u00f3n","year":"2010","unstructured":"Falc\u00f3n J, Migaud H, Mu\u00f1oz-Cueto JA, Carrillo M (2010) Current knowledge on the melatonin system in teleost fish. Gen Comp Endocrinol 165:469\u2013482","journal-title":"Gen Comp Endocrinol"},{"key":"966_CR22","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.ygcen.2006.12.008","volume":"152","author":"B Fern\u00e1ndez-Dur\u00e1n","year":"2007","unstructured":"Fern\u00e1ndez-Dur\u00e1n B, Ruibal C, Polakof S, Ceinos RM, Soengas JL, M\u00edguez JM (2007) Evidence for arylalkylamine N-acetyltransferase (AANAT2) expression in rainbow trout peripheral tissues with emphasis in the gastrointestinal tract. Gen Comp Endocrinol 152:289\u2013294","journal-title":"Gen Comp Endocrinol"},{"key":"966_CR23","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/j.gastro.2006.11.002","volume":"132","author":"MD Gershon","year":"2007","unstructured":"Gershon MD, Tack J (2007) The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology 132:397\u2013414","journal-title":"Gastroenterology"},{"key":"966_CR24","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cbpa.2006.02.028","volume":"144","author":"M Gesto","year":"2006","unstructured":"Gesto M, Tintos A, Soengas JL, M\u00edguez JM (2006) Effects of acute and prolonged naphthalene exposure on brain monoaminergic neurotransmitters in rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol C 144:173\u2013183","journal-title":"Comp Biochem Physiol C"},{"key":"966_CR25","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1743-7075-2-22","volume":"2","author":"R Hardeland","year":"2005","unstructured":"Hardeland R, Pandi-Perumal SR (2005) Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. Nutr Metabol 2:22","journal-title":"Nutr Metabol"},{"key":"966_CR26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00360-006-0131-6","volume":"177","author":"MJ Herrero","year":"2007","unstructured":"Herrero MJ, Mart\u00ednez FJ, M\u00edguez JM, Madrid JA (2007) Response of plasma and gastrointestinal melatonin, plasma cortisol and activity rhythms of European sea bass (Dicentrarchus labrax) to dietary supplementation with tryptophan and melatonin. J Comp Physiol B 177:319\u2013326","journal-title":"J Comp Physiol B"},{"key":"966_CR27","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/BF01923948","volume":"49","author":"G Huether","year":"1993","unstructured":"Huether G (1993) The contribution of extrapineal sites of melatonin synthesis to circulating melatonin levels in higher vertebrates. Experientia 49:665\u2013670","journal-title":"Experientia"},{"key":"966_CR28","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/0024-3205(92)90402-B","volume":"51","author":"G Huether","year":"1992","unstructured":"Huether G, Poegeller B, Reimer R, George A (1992) Effect of tryptophan administration on circulating melatonin levels in chicks and rats: evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract. Life Sci 51:945\u2013953","journal-title":"Life Sci"},{"key":"966_CR29","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1600-079X.1998.tb00527.x","volume":"24","author":"G Huether","year":"1998","unstructured":"Huether G, Messner M, Rodenbeck A, Hardeland R (1998) Effect of continuos melatonin infusions on steady-state plasma melatonin levels in rats under near physiological conditions. J Pineal Res 24:146\u2013151","journal-title":"J Pineal Res"},{"key":"966_CR30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ygcen.2007.06.013","volume":"154","author":"M Iigo","year":"2007","unstructured":"Iigo M, Abe T, Kambayashi S, Oikawa K, Masuda T, Mizusawa K, Kitamura S, Azuma T, Takagi Y, Aida K, Yanagisawa T (2007) Lack of circadian regulation of in vitro melatonin release from the pineal organ of salmonid teleosts. Gen Comp Endocrinol 154:91\u201397","journal-title":"Gen Comp Endocrinol"},{"key":"966_CR32","first-page":"1047","volume":"9","author":"H Kezuka","year":"1992","unstructured":"Kezuka H, Iigo M, Furukawa K, Aida K, Hanyu I (1992) Effects of photoperiod, pinealectomy and ophthalmectomy on circulating melatonin rhythms in the goldfish, Carassius auratus. Zool Sci 9:1047\u20131053","journal-title":"Zool Sci"},{"key":"966_CR33","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1074\/jbc.R600036200","volume":"282","author":"DC Klein","year":"2007","unstructured":"Klein DC (2007) Arylalkylamine N-acetyltransferase: the \u201ctimezyme\u201d. J Biol Chem 282:4233\u20134237","journal-title":"J Biol Chem"},{"key":"966_CR34","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1600-079X.2004.00201.x","volume":"38","author":"O Lepage","year":"2005","unstructured":"Lepage O, Larson ET, Mayer I, Winberg S (2005) Tryptophan affects both gastrointestinal melatonin production and interrenal activity in stressed and nonstressed rainbow trout. J Pineal Res 38:264\u2013271","journal-title":"J Pineal Res"},{"key":"966_CR35","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method. Methods 25:402\u2013408","journal-title":"Methods"},{"key":"966_CR36","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1242\/jeb.051516","volume":"214","author":"MA L\u00f3pez-Pati\u00f1o","year":"2014","unstructured":"L\u00f3pez-Pati\u00f1o MA, Rodr\u00edguez-Illamola A, Gesto M, Soengas JL, M\u00edguez JM (2014) Changes in plasma melatonin levels and pineal organ melatonin synthesis following acclimation of rainbow trout (Oncorhynchys mykiss) to different water salinities. J Exp Biol 214:928\u2013936","journal-title":"J Exp Biol"},{"key":"966_CR37","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1600-079X.2007.00480.x","volume":"43","author":"H Migaud","year":"2007","unstructured":"Migaud H, Davie A, Mart\u00ednez Chavez CC, Al-Khamees S (2007) Evidence for differential photic regulation of pineal melatonin synthesis in teleosts. J Pineal Res 43:327\u2013335","journal-title":"J Pineal Res"},{"key":"966_CR38","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1097\/00001756-200011090-00015","volume":"9","author":"K Mizusawa","year":"2000","unstructured":"Mizusawa K, Iigo M, Masuda T, Aida K (2000) Photic regulation of arylalkylamine N-acetyltransferase 1 mRNA in trout retina. Neuroreport 9:3473\u20133477","journal-title":"Neuroreport"},{"key":"966_CR39","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/09291016.2013.817139","volume":"45","author":"S Mukherjeea","year":"2014","unstructured":"Mukherjeea S, Moniruzzamana M, Maitraa SK (2014a) Daily and seasonal profiles of gut melatonin and their temporal relationship with pineal and serum melatonin in carp Catla catla under natural photo-thermal conditions. Biol Rhythm Res 45:301\u2013315","journal-title":"Biol Rhythm Res"},{"key":"966_CR40","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1080\/09291016.2014.923618","volume":"45","author":"S Mukherjeea","year":"2014","unstructured":"Mukherjeea S, Moniruzzamana M, Maitraa SK (2014b) Impact of artificial lighting conditions on the diurnal profiles of gut melatonin in a surface dwelling carp (Catla catla). Biol Rhythm Res 45:831\u2013848","journal-title":"Biol Rhythm Res"},{"key":"966_CR41","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1016\/j.jchromb.2009.06.001","volume":"877","author":"JLP Mu\u00f1oz","year":"2009","unstructured":"Mu\u00f1oz JLP, Ceinos RM, Soengas JL, M\u00edguez JM (2009) A simple and sensitive method for determination of melatonin in plasma, bile and intestinal tissues by high performance liquid chromatography with fluorescence detection. J Chromatogr B 877:2173\u20132177","journal-title":"J Chromatogr B"},{"key":"966_CR42","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.neuint.2013.02.023","volume":"62","author":"LG Nisembaum","year":"2013","unstructured":"Nisembaum LG, Tinoco AB, Moure AL, Alonso G\u00f3mez AL, Delgado MJ, Valenciano AI (2013) Arylalkylamine-N-acetyltransferase (AANAT) acetylates dopamine in the digestive tract of goldfish: a role in intestinal melatonin. Neurochem Int 62:873\u2013880","journal-title":"Neurochem Int"},{"key":"966_CR43","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/07420520500482074","volume":"23","author":"P P\u00e9vet","year":"2006","unstructured":"P\u00e9vet P, Agez L, Bothorel B, Saboureau M, Gauer F, Laurent V, Masson-P\u00e9vet M (2006) Melatonin in the multi-oscillatory mammalian circadian world. Chronobiol Int 23:39\u201351","journal-title":"Chronobiol Int"},{"key":"966_CR44","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/BF01923947","volume":"49","author":"RJ Reiter","year":"1993","unstructured":"Reiter RJ (1993) The melatonin rhythm: both a clock and a calendar. Experientia 49:654\u2013664","journal-title":"Experientia"},{"key":"966_CR45","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S0031-9384(99)00250-4","volume":"69","author":"FJ S\u00e1nchez-V\u00e1zquez","year":"2000","unstructured":"S\u00e1nchez-V\u00e1zquez FJ, Iigo M, Madrid JA, Tabata M (2000) Pinealectomy does not affect the entrainment to light nor the generation of the circadian demand-feeding rhythms of rainbow trout. Physiol Behav 69:455\u2013461","journal-title":"Physiol Behav"},{"key":"966_CR46","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.neuropharm.2008.07.016","volume":"55","author":"R Spiller","year":"2008","unstructured":"Spiller R (2008) Serotonin and GI clinical disorders. Neuropharmacology 55:1072\u20131080","journal-title":"Neuropharmacology"},{"key":"966_CR47","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1016\/S0024-3205(99)00519-6","volume":"65","author":"DX Tan","year":"1999","unstructured":"Tan DX, Manchester LC, Reiter RJ, Qi W, Hanes M, Farley NJ (1999) High physiological levels of melatonin in the bile of mammals. Life Sci 65:2523\u20132529","journal-title":"Life Sci"},{"key":"966_CR48","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/074873099129000588","volume":"14","author":"TJ Van`t Hof","year":"1999","unstructured":"Van`t Hof TJ, Gwinner E (1999) Influence of pinealectomy and pineal stalk deflection on circadian gastrointestinal tract melatonin rhythms in zebra fish (Taenioppygia guttata). J Biol Rhythms 14:185\u2013189","journal-title":"J Biol Rhythms"},{"key":"966_CR49","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s00360-009-0373-1","volume":"179","author":"E Velarde","year":"2009","unstructured":"Velarde E, Alonso-G\u00f3mez AL, Azpeleta C, Isorna E, Delgado MJ (2009) Melatonin attenuates the acetylcholine-induced contraction in isolated intestine of a teleost fish. J Comp Physiol B 179:951\u2013959","journal-title":"J Comp Physiol B"},{"key":"966_CR50","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3109\/07420528.2010.496911","volume":"27","author":"E Velarde","year":"2010","unstructured":"Velarde E, Cerd\u00e1-Reverter JM, Alonso-G\u00f3mez AL, S\u00e1nchez E, Isorna E, Delgado MJ (2010) Melatonin-synthesizing enzymes in pineal, retina, liver, and gut of the goldfish (Carassius auratus): mRNA expression pattern and regulation of daily rhythms by lighting conditions. Chronobiol Int 27:1178\u20131201","journal-title":"Chronobiol Int"},{"key":"966_CR51","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.physbeh.2006.10.017","volume":"90","author":"LM Vera","year":"2007","unstructured":"Vera LM, De Pedro N, G\u00f3mez-Mil\u00e1n E, Delgado MJ, S\u00e1nchez-Muros MJ, Madrid JA, S\u00e1nchez-V\u00e1zquez FJ (2007) Feeding entrainment of locomotor activity rhythms, digestive enzymes and neuroendocrine factor in goldfish. Physiol Behav 90:518\u2013524","journal-title":"Physiol Behav"},{"key":"966_CR52","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1111\/j.1460-9568.2007.05578.x","volume":"25","author":"R Vuilleumier","year":"2007","unstructured":"Vuilleumier R, Boeuf G, Fuentes M, Gehring WJ, Falc\u00f3n J (2007) Cloning and early expression pattern of two melatonin biosynthesis enzymes in the turbot (Scophthalmus maximus). Eur J Neurosci 25:3047\u20133057","journal-title":"Eur J Neurosci"},{"key":"966_CR53","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/0024-3205(93)90106-D","volume":"52","author":"H Yaga","year":"1993","unstructured":"Yaga H, Reiter RJ, Richardson BA (1993) Tryptophan loading increase day time serum melatonin in intac and pinealectomized rats. Life Sci 52:1231\u20131238","journal-title":"Life Sci"}],"container-title":["Journal of Comparative Physiology B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00360-016-0966-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00360-016-0966-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00360-016-0966-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T10:42:53Z","timestamp":1559040173000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00360-016-0966-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,12]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["966"],"URL":"https:\/\/doi.org\/10.1007\/s00360-016-0966-4","relation":{},"ISSN":["0174-1578","1432-136X"],"issn-type":[{"value":"0174-1578","type":"print"},{"value":"1432-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,12]]}}}