{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T18:24:16Z","timestamp":1780511056695,"version":"3.54.1"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:00:00Z","timestamp":1709942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:00:00Z","timestamp":1709942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100000038","name":"NSERC","doi-asserted-by":"crossref","award":["RGPIN-2018-04172"],"award-info":[{"award-number":["RGPIN-2018-04172"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Comp Physiol B"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s00360-024-01539-3","type":"journal-article","created":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T12:01:47Z","timestamp":1709985707000},"page":"155-166","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An investigation of gill and blood carbonic anhydrase characteristics in three basal actinopterygian species: alligator gar (Atractosteus spatula), white sturgeon (Acipenser transmontanus) and Senegal bichir (Polypterus senegalus)"],"prefix":"10.1007","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1791-8155","authenticated-orcid":false,"given":"Charlotte","family":"Nelson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3025-1957","authenticated-orcid":false,"given":"Emily M.","family":"Standen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0122-9387","authenticated-orcid":false,"given":"Peter J.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3695-7707","authenticated-orcid":false,"given":"Colin J.","family":"Brauner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,9]]},"reference":[{"key":"1539_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/BFb0034292","author":"C Baur","year":"1974","unstructured":"Baur C (1974) On the respiratory function of hemoglobin. Rev Physiol Biochem Pharmacol. https:\/\/doi.org\/10.1007\/BFb0034292","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"1539_CR2","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.resp.2006.01.002","volume":"154","author":"M Berenbrink","year":"2006","unstructured":"Berenbrink M (2006) Evolution of vertebrate haemoglobins: histidine side chains, specific buffer value and Bohr effect. Respir Physiol Neurobiol 154:165\u2013184","journal-title":"Respir Physiol Neurobiol"},{"key":"1539_CR3","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1126\/science.1107793","volume":"307","author":"M Berenbrink","year":"2005","unstructured":"Berenbrink M, Koldkj\u00e6r P, Kepp O, Cossins AR (2005) Evolution of oxygen secretion in fishes and the emergence of a complex physiological system. Science 307:1752\u20131757","journal-title":"Science"},{"key":"1539_CR4","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1111\/j.1748-1716.2010.02243.x","volume":"202","author":"M Berenbrink","year":"2011","unstructured":"Berenbrink M, Koldkj\u00e6r P, Hannah Wright E, Kepp O, Jos\u00e9 da Silva A (2011) Magnitude of the root effect in red blood cells and haemoglobin solutions of fishes: a tribute to August Krogh. Acta Physiol 202:583\u2013592","journal-title":"Acta Physiol"},{"key":"1539_CR5","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1111\/j.1748-1716.1904.tb01382.x","volume":"16","author":"C Bohr","year":"1904","unstructured":"Bohr C, Hasselbalch K, Krogh A (1904) Ueber einen inbiologischer beziehung wichtigen einfluss, den die kohlen-sa \u0308urespannung des blutes auf dessen sauerstoffbindung \u00fcbt. Skand Arch Physiol 16:402\u2013412","journal-title":"Skand Arch Physiol"},{"key":"1539_CR6","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1113\/jphysiol.1938.sp003574","volume":"91","author":"VH Booth","year":"1938","unstructured":"Booth VH (1938) The carbonic anhydrase inhibitor in serum. J Physiol 91:474\u2013489","journal-title":"J Physiol"},{"key":"1539_CR7","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/S1546-5098(07)26005-4","volume-title":"Primitive Fishes","author":"CJ Brauner","year":"2007","unstructured":"Brauner CJ, Berenbrink M (2007) Gas transport and exchange. In: McKenzie DJ, Farrell AP, Brauner CJ (eds) Primitive Fishes, vol 26. Elsevier, pp 213\u2013282"},{"key":"1539_CR8","first-page":"283","volume-title":"Fish respiration","author":"CJ Brauner","year":"1998","unstructured":"Brauner CJ, Randall DJ (1998) The linkage between oxygen and carbon dioxide transport. In: Perry SF, Tufts BL (eds) Fish respiration, vol 17. Elsevier, pp 283\u2013319"},{"key":"1539_CR9","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-0348-8446-4","volume-title":"The carbonic anhydrases","author":"WR Chegwidden","year":"2000","unstructured":"Chegwidden WR, Carter ND, Edwards YH (2000) The carbonic anhydrases. Springer"},{"key":"1539_CR10","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s003600100196","volume":"171","author":"PR Desforges","year":"2001","unstructured":"Desforges PR, Gilmour KM, Perry SF (2001) The effects of exogenous extracellular carbonic anhydrase on CO2 excretion in rainbow trout (Oncorhynchus mykiss): role of plasma buffering capacity. J Comp Physiol B 171:465\u2013473","journal-title":"J Comp Physiol B"},{"key":"1539_CR11","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s00360-020-01270-9","volume":"190","author":"AM Dichiera","year":"2020","unstructured":"Dichiera AM, McMillan OJL, Clifford AM, Goss GG, Brauner CJ, Esbaugh AJ (2020) The importance of a single amino acid substitution in reduced red blood cell carbonic anhydrase function of early-diverging fish. J Comp Physiol B 190:287\u2013296","journal-title":"J Comp Physiol B"},{"key":"1539_CR12","doi-asserted-by":"publisher","first-page":"232991","DOI":"10.1242\/jeb.232991","volume":"223","author":"AM Dichiera","year":"2020","unstructured":"Dichiera AM, Esbaugh AJ (2020) Red blood cell carbonic anhydrase mediates oxygen delivery via the root effect in red drum. J Exp Biol 223:232991","journal-title":"J Exp Biol"},{"key":"1539_CR13","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.resp.2006.03.007","volume":"154","author":"AJ Esbaugh","year":"2006","unstructured":"Esbaugh AJ, Tufts BL (2006) The structure and function of carbonic anhydrase isozymes in the respiratory system of vertebrates. Respir Physiol Neurobiol 154:185\u2013198","journal-title":"Respir Physiol Neurobiol"},{"key":"1539_CR14","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1152\/ajprenal.00328.2005","volume":"291","author":"T Georgalis","year":"2006","unstructured":"Georgalis T, Gilmour KM, Yorston J, Perry SF (2006) Roles of cytosolic and membrane-bound carbonic anhydrase in renal control of acid\u2013base balance in rainbow trout, Oncorhynchus mykiss. Am J Physiol Renal Physiol 291:407\u2013421","journal-title":"Am J Physiol Renal Physiol"},{"key":"1539_CR15","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1242\/jeb.201.14.2205","volume":"201","author":"MR Gervais","year":"1998","unstructured":"Gervais MR, Tufts BL (1998) Evidence for membrane-bound carbonic anhydrase in the air bladder of bowfin (Amia calva), a primitive air breathing fish. J Exp Biol 201:2205\u20132212","journal-title":"J Exp Biol"},{"key":"1539_CR16","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.cbpa.2010.06.161","volume":"157","author":"KM Gilmour","year":"2010","unstructured":"Gilmour KM (2010) Perspectives on carbonic anhydrase. Comp Biochem Physiol A 157:193\u2013197","journal-title":"Comp Biochem Physiol A"},{"key":"1539_CR17","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1152\/ajpregu.00219.2003","volume":"286","author":"KM Gilmour","year":"2004","unstructured":"Gilmour KM, Perry SF (2004) Branchial membrane-associated carbonic anhydrase activity maintains CO2 excretion in severely anaemic dogfish. Am J Physiol Regul Integr Comp Physiol 286:1138\u20131148","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"1539_CR18","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1242\/jeb.200.1.173","volume":"200","author":"KM Gilmour","year":"1997","unstructured":"Gilmour KM, Henry RP, Wood CM, Perry SF (1997) Extracellular carbonic anhydrase and an acid-base disequilibrium in the blood of the dogfish, Squalus acanthias. J Exp Biol 200:173\u2013183","journal-title":"J Exp Biol"},{"key":"1539_CR19","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1086\/322157","volume":"74","author":"KM Gilmour","year":"2001","unstructured":"Gilmour KM, Perry SF, Bernier NJ, Henry RP, Wood CM (2001) Extracellular carbonic anhydrase in the dogfish, Squalus acanthias: a role in CO2 excretion. Physiol Biochem Zool 74:477\u2013492","journal-title":"Physiol Biochem Zool"},{"key":"1539_CR20","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s003600100229","volume":"172","author":"KM Gilmour","year":"2002","unstructured":"Gilmour KM, Shah B, Szebedinszky C (2002) An investigation of carbonic anhydrase activity in the gills and blood plasma of brown bullhead (Ameiurus nebulosus), longnose skate (Raja rhina), and spotted ratfish (Hydrolagus colliei). J Comp Physiol B 172:77\u201386","journal-title":"J Comp Physiol B"},{"key":"1539_CR21","doi-asserted-by":"crossref","unstructured":"Gilmour KM (1998) Causes and consequences of acid-base disequilibria. In: SF Perry, B Tufts (eds.), Fish respiration, pp 321\u2013343","DOI":"10.1016\/S1546-5098(08)60265-4"},{"key":"1539_CR22","doi-asserted-by":"publisher","first-page":"jeb190918","DOI":"10.1242\/jeb.190918","volume":"221","author":"TS Harter","year":"2018","unstructured":"Harter TS, Sackville MA, Wilson JM, Metzger DCH, Egginton S, Esbaugh AJ, Farrell AP, Brauner CJ (2018a) A solution to Nature\u2019s haemoglobin knockout: a plasma-accessible carbonic anhydrase catalyses CO2 excretion in Antarctic icefish gills. J Exp Biol 221:jeb190918","journal-title":"J Exp Biol"},{"key":"1539_CR23","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1152\/ajpregu.00062.2018","volume":"315","author":"TS Harter","year":"2018","unstructured":"Harter TS, May A, Federspiel WJ, Supuran CT, Brauner CJ (2018b) The time-course of red blood cell intracellular pH recovery following short-circuiting in relation to venous transit times in rainbow trout, Oncorhynchus mykiss. Am J Physiol Regul Integr Comp Physiol 315:397\u2013407","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"1539_CR24","first-page":"1","volume-title":"The cardiovascular system: development, plasticity and physiological responses","author":"TS Harter","year":"2017","unstructured":"Harter TS, Brauner CJ (2017) The O2 and CO2 transport system in teleosts and the specialized mechanisms that enhance Hb-O2 unloading to tissues. In: Gamperl AK, Gillis TE, Farrell AP, Brauner CJ (eds) The cardiovascular system: development, plasticity and physiological responses, vol 36B. Elsevier, pp 1\u2013106"},{"key":"1539_CR25","doi-asserted-by":"publisher","first-page":"20190339","DOI":"10.1098\/rspb.2019.0339","volume":"286","author":"TS Harter","year":"2019","unstructured":"Harter TS, Zanuzzo FS, Supuran CT, Gamperl AK, Brauner CJ (2019) Functional support for a novel mechanism that enhances tissue oxygen extraction in a teleost fish. Proc R Soc B 286:20190339","journal-title":"Proc R Soc B"},{"key":"1539_CR26","doi-asserted-by":"publisher","first-page":"246016","DOI":"10.1242\/jeb.246016","volume":"226","author":"TS Harter","year":"2023","unstructured":"Harter TS, Smith EA, Tresguerres M (2023) A novel perspective on the evolutionary loss of plasma-accessible carbonic anhydrase at the teleost gill. J Exp Biol 226:246016","journal-title":"J Exp Biol"},{"key":"1539_CR27","first-page":"397","volume-title":"Acid-bas regulation in animals","author":"N Heisler","year":"1986","unstructured":"Heisler N (1986) Comparative aspects of acid-base regulation. In: Heisler N (ed) Acid-bas regulation in animals. Elsevier, pp 397\u2013450"},{"key":"1539_CR28","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1152\/jappl.1993.75.4.1642","volume":"75","author":"TA Heming","year":"1993","unstructured":"Heming TA, Vanoye CG, Stabenau EK, Roush ED, Fierke CA, Bidani A (1993) Inhibitor sensitivity of pulmonary vascular carbonic anhydrase. J Appl Physiol 75:1642\u20131649","journal-title":"J Appl Physiol"},{"key":"1539_CR29","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/jez.1402480104","volume":"248","author":"RP Henry","year":"1988","unstructured":"Henry RP (1988) Multiple functions of carbonic anhydrase in the crustacean gill. J Exp Zool 248:19\u201324","journal-title":"J Exp Zool"},{"key":"1539_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0034-5687(00)00110-9","volume":"121","author":"RP Henry","year":"2000","unstructured":"Henry RP, Swenson ER (2000) The distribution and physiological significance of carbonic anhydrase in vertebrate gas exchange organs. Respir Physiol 121:1\u201312","journal-title":"Respir Physiol"},{"key":"1539_CR31","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1086\/515878","volume":"70","author":"RP Henry","year":"1997","unstructured":"Henry RP, Gilmour KM, Wood CM, Perry SF (1997) Extracellular carbonic anhydrase activity and carbonic anhydrase inhibitors in the circulatory system of fish. Physiol Zool 70:650\u2013659","journal-title":"Physiol Zool"},{"key":"1539_CR32","first-page":"75","volume-title":"Fish physiology","author":"RP Henry","year":"1998","unstructured":"Henry RP, Heming TA (1998) Carbonic anhydrase and respiratory gas exchange. In: Perry SF, Tufts B (eds) Fish physiology, vol 17. Academic Press, pp 75\u2013113"},{"key":"1539_CR33","first-page":"199","volume-title":"The carbonic anhydrases","author":"RP Henry","year":"1991","unstructured":"Henry RP (1991) Techniques for measuring carbonic anhydrase activity in vitro. In: Dodgson SJ, Tashian RE, Gros G, Carter ND (eds) The carbonic anhydrases. Springer, pp 199\u2013125"},{"key":"1539_CR34","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1152\/jappl.1986.60.1.191","volume":"60","author":"EP Hill","year":"1986","unstructured":"Hill EP (1986) Inhibition of carbonic anhydrase by plasma of dogs and rabbits. J Appl Physiol 60:191\u2013197","journal-title":"J Appl Physiol"},{"key":"1539_CR35","doi-asserted-by":"publisher","first-page":"6249","DOI":"10.1073\/pnas.1719358115","volume":"115","author":"LC Hughes","year":"2018","unstructured":"Hughes LC, Guillermo O, Huang Y, Sun Y, Baldwin CC, Thompson AW, Arcila D, Bentacur-R R, Li C, Becker L, Bellora N, Zhao X, Li X, Wang M, Fang C, Xie B, Zhou Z, Huang H, Chen S, Venkatesh B, Shi Q (2018) Comprehensive phylogeny of ray-finned fishes (Actinopterygii) based on transcriptomic and genomic data. PNAS 115:6249\u20136254","journal-title":"PNAS"},{"key":"1539_CR36","doi-asserted-by":"publisher","first-page":"201300059","DOI":"10.3389\/fphys.2013.00059","volume":"4","author":"Y Ito","year":"2013","unstructured":"Ito Y, Kobayashi S, Nakamura N, Miyagi H, Esaki M, Hoshijima K, Hirose S (2013) Close association of carbonic anhydrase (CA2a and CA15a), Na+\/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake. Front Physiol 4:201300059","journal-title":"Front Physiol"},{"key":"1539_CR37","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1242\/jeb.143.1.225","volume":"143","author":"FB Jensen","year":"1989","unstructured":"Jensen FB (1989) Hydrogen ion equilibria in fish haemoglobins. J Exp Biol 143:225\u2013234","journal-title":"J Exp Biol"},{"key":"1539_CR38","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1111\/j.1365-201X.2004.01361.x","volume":"182","author":"FB Jensen","year":"2004","unstructured":"Jensen FB (2004) Red blood cell pH, the Bohr effect, and other oxygenation linked phenomena in blood O2 and CO2 transport. Acta Physiol Scandia 182:215\u2013227","journal-title":"Acta Physiol Scandia"},{"key":"1539_CR39","doi-asserted-by":"publisher","first-page":"3387","DOI":"10.1242\/jeb.023697","volume":"212","author":"FB Jensen","year":"2009","unstructured":"Jensen FB (2009) The dual roles of red blood cells in tissue oxygen delivery: oxygen carriers and regulators of local blood flow. J Exp Biol 212:3387\u20133393","journal-title":"J Exp Biol"},{"key":"1539_CR40","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1242\/jeb.198.1.31","volume":"198","author":"J Lessard","year":"1995","unstructured":"Lessard J, Val A, Aota A, Randall DJ (1995) Why is there no carbonic anhydrase activity available to fish plasma? J Exp Biol 198:31\u201338","journal-title":"J Exp Biol"},{"key":"1539_CR41","doi-asserted-by":"publisher","first-page":"C1250","DOI":"10.1152\/ajpcell.00021.2008","volume":"294","author":"TY Lin","year":"2008","unstructured":"Lin TY, Liao BK, Horng JL, Yan JJ, Hsiao CD, Hwang PP (2008) Carbonic anhydrase 2-like a and 15a are involved in acid-base regulation and Na+ uptake in zebrafish H+-ATPase-rich cells. Am J Phys Cell Physiol 294:C1250\u2013C1260","journal-title":"Am J Phys Cell Physiol"},{"key":"1539_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0163-7258(96)00198-2","volume":"74","author":"S Lindskog","year":"1997","unstructured":"Lindskog S (1997) Structure and mechanism of carbonic anhydrase. Pharmacol Ther 74:1\u201320","journal-title":"Pharmacol Ther"},{"key":"1539_CR43","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1086\/705402","volume":"92","author":"OJL McMillan","year":"2019","unstructured":"McMillan OJL, Dichiera AM, Harter TS, Wilson JM, Esbaugh AJ, Brauner CJ (2019) Blood and gill carbonic anhydrase in the context of a Chondrichthyan model of CO2 excretion. Physiol Biochem Zool 92:554\u2013566","journal-title":"Physiol Biochem Zool"},{"key":"1539_CR44","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1152\/ajpcell.1989.256.4.C728","volume":"256","author":"R Motais","year":"1989","unstructured":"Motais R, Fievet B, Garcia-Romeu F, Thomas S (1989) Na+\/H+ exchange and pH regulation in red blood cells: role of uncatalyzed H2CO3 dehydration. Am J Physiol 256:728\u2013735","journal-title":"Am J Physiol"},{"key":"1539_CR45","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s00360-023-01484-7","volume":"193","author":"C Nelson","year":"2023","unstructured":"Nelson C, Dichiera AM, Jung EH, Brauner CJ (2023) An atlas of plasma accessible carbonic anhydrase availability in the model teleost, the rainbow trout. J Comp Physiol 193:293\u2013305","journal-title":"J Comp Physiol"},{"key":"1539_CR46","unstructured":"Nelson C (2023) Patterns of plasma accessible carbonic anhydrase localisation in derived, basal, and developing fishes. PhD thesis, University of British Columbia, Vancouver"},{"key":"1539_CR47","first-page":"287","volume":"2","author":"M Nikinmaa","year":"1982","unstructured":"Nikinmaa M (1982) Effects of adrenaline on red cell volume and concentration gradient of protons across the red cell membrane in the rainbow trout, Salmo gairdneri. Mol Physiol 2:287\u2013297","journal-title":"Mol Physiol"},{"key":"1539_CR48","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1152\/physrev.1992.72.2.301","volume":"72","author":"M Nikinmaa","year":"1992","unstructured":"Nikinmaa M (1992) Membrane transport and control of hemoglobin-oxygen affinity in nucleated erythrocytes. Physiol Rev 72:301\u2013321","journal-title":"Physiol Rev"},{"key":"1539_CR49","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1242\/jeb.200.2.369","volume":"200","author":"M Nikinmaa","year":"1997","unstructured":"Nikinmaa M (1997) Oxygen and carbon dioxide transport in vertebrate erythrocytes: an evolutionary change in the role of membrane transport. J Exp Biol 200:369\u2013380","journal-title":"J Exp Biol"},{"key":"1539_CR51","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1242\/jeb.154.1.257","volume":"154","author":"M Nikinmaa","year":"1990","unstructured":"Nikinmaa M, Tiihonen K, Paajaste M (1990) Adrenergic control of red cell pH in salmonid fish: roles of the sodium\/ proton exchange, Jacobs\u2013Stewart cycle and membrane potential. J Exp Biol 154:257\u2013271","journal-title":"J Exp Biol"},{"key":"1539_CR52","doi-asserted-by":"publisher","DOI":"10.1111\/apha.13299","volume":"272","author":"M Nikinmaa","year":"2019","unstructured":"Nikinmaa M, Berenbrink M, Brauner CJ (2019) Regulation of erythrocyte function: multiple evolutionary solutions for respiratory gas transport and its regulation in fish. Acta Physiol 272:e13299","journal-title":"Acta Physiol"},{"key":"1539_CR53","doi-asserted-by":"crossref","unstructured":"Nikinmaa M (1990) Vertebrate red blood cells: adaptations of function to respiratory requirements. Springer-Verlag","DOI":"10.1007\/978-3-642-83909-2"},{"key":"1539_CR54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00898-997-0001-z","volume":"2","author":"SF Perry","year":"1997","unstructured":"Perry SF, Brauner CJ, Tufts B, Gilmour KM (1997) Acid\u2013base disequilibrium in venous blood of rainbow trout (Oncorhynchus mykiss). Exp Biol Online 2:1\u201310","journal-title":"Exp Biol Online"},{"key":"1539_CR55","doi-asserted-by":"publisher","first-page":"3003","DOI":"10.1242\/jeb.203.19.3003","volume":"203","author":"T Peters","year":"2000","unstructured":"Peters T, Papadopoulos F, Kubis H-P, Gros G (2000) Properties of a carbonic anhydrase inhibitor protein in flounder serum. J Exp Biol 203:3003\u20133009","journal-title":"J Exp Biol"},{"key":"1539_CR56","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1038\/sj.ki.5002020","volume":"71","author":"JM Purkerson","year":"2007","unstructured":"Purkerson JM, Schwartz GJ (2007) The role of carbonic anhydrase in renal physiology. Kidney Int 71:103\u2013115","journal-title":"Kidney Int"},{"key":"1539_CR57","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S1095-6433(97)00412-1","volume":"119","author":"DJ Randall","year":"1996","unstructured":"Randall DJ, Brauner CJ (1996) Interactions between ion and gas transfer in freshwater teleost fish. Comp Biochem Physiol A 119:3\u20138","journal-title":"Comp Biochem Physiol A"},{"key":"1539_CR58","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1242\/jeb.093526","volume":"217","author":"DJ Randall","year":"2014","unstructured":"Randall DJ, Rummer JL, Wilson JM, Wang S, Brauner CJ (2014) A unique mode of tissue oxygenation and the adaptive radiation of teleost fishes. J Exp Biol 217:1205\u20131214","journal-title":"J Exp Biol"},{"key":"1539_CR59","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1007\/s00360-010-0450-5","volume":"180","author":"MD Regan","year":"2010","unstructured":"Regan MD, Brauner CJ (2010) The evolution of Root effect hemoglobins in the absence of intracellular pH protection of the red blood cell: insights from primitive fishes. J Comp Physiol B 180:695\u2013706","journal-title":"J Comp Physiol B"},{"key":"1539_CR60","doi-asserted-by":"publisher","first-page":"427","DOI":"10.2307\/1536959","volume":"61","author":"RW Root","year":"1931","unstructured":"Root RW (1931) The respiratory function of the blood of marine fishes. Biol Bull 61:427\u2013456","journal-title":"Biol Bull"},{"key":"1539_CR61","doi-asserted-by":"publisher","first-page":"2319","DOI":"10.1242\/jeb.054049","volume":"214","author":"JL Rummer","year":"2011","unstructured":"Rummer JL, Brauner CJ (2011) Plasma-accessible carbonic anhydrase at the tissue of a teleost fish may greatly enhance oxygen delivery: in vitro evidence in rainbow trout, Oncorhynchus mykiss. J Exp Biol 214:2319\u20132328","journal-title":"J Exp Biol"},{"key":"1539_CR62","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1126\/science.1233692","volume":"340","author":"JL Rummer","year":"2013","unstructured":"Rummer JL, McKenzie DJ, Innocenti A, Supuran CT, Brauner CJ (2013) Root effect hemoglobin may have evolved to enhance general tissue oxygen delivery. Science 340:1327\u20131329","journal-title":"Science"},{"key":"1539_CR63","doi-asserted-by":"publisher","first-page":"111101","DOI":"10.1016\/j.cbpa.2021.111101","volume":"264","author":"JJ Shu","year":"2022","unstructured":"Shu JJ, Heuer RM, Hannan KD, Stieglitz JD, Benetti DD, Rummer JL, Grosell M, Brauner CJ (2022) Enhanced oxygen unloading in two marine percomorph teleosts. Comp Biochem Physiol A 264:111101","journal-title":"Comp Biochem Physiol A"},{"key":"1539_CR64","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1021\/ar00145a005","volume":"21","author":"DN Silverman","year":"1988","unstructured":"Silverman DN (1988) The catalytic mechanism of carbonic anhydrase: Implications of a rate limiting proteolysis of water. Acc Chem Res 21:30\u201336","journal-title":"Acc Chem Res"},{"key":"1539_CR65","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1002\/bies.950100603","volume":"10","author":"RE Tashian","year":"1989","unstructured":"Tashian RE (1989) The carbonic anhydrases: widening perspectives on their evolution, expression and function. BioEssays 10:186\u2013192","journal-title":"BioEssays"},{"key":"1539_CR66","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/S1095-6433(03)00159-4","volume":"136","author":"BL Tufts","year":"2003","unstructured":"Tufts BL, Esbaugh AJ, Lund SG (2003) Comparative physiology and molecular evolution of carbonic anhydrase in the erythrocytes of early vertebrates. Comp Biochem Physiol A 136:259\u2013269","journal-title":"Comp Biochem Physiol A"},{"key":"1539_CR69","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/0034-5687(94)90080-9","volume":"98","author":"CM Wood","year":"1994","unstructured":"Wood CM, Perry SF, Walsh PJ, Thomas S (1994) HCO3- dehydration by the blood of an elasmobranch in the absence of a Haldane effect. Respir Physiol 98:319\u2013337","journal-title":"Respir Physiol"},{"key":"1539_CR70","doi-asserted-by":"publisher","first-page":"8795","DOI":"10.1016\/S0021-9258(19)38958-6","volume":"265","author":"XL Zhu","year":"1990","unstructured":"Zhu XL, Sly WS (1990) Carbonic anhydrase IV from human lung: purification, characterization, and comparison with membrane carbonic anhydrase from human kidney. J Biol Chem 265:8795\u20138801","journal-title":"J Biol Chem"}],"container-title":["Journal of Comparative Physiology B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00360-024-01539-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00360-024-01539-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00360-024-01539-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T20:07:44Z","timestamp":1714939664000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00360-024-01539-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,9]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["1539"],"URL":"https:\/\/doi.org\/10.1007\/s00360-024-01539-3","relation":{},"ISSN":["0174-1578","1432-136X"],"issn-type":[{"value":"0174-1578","type":"print"},{"value":"1432-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,9]]},"assertion":[{"value":"29 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}