{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:57:54Z","timestamp":1768870674007,"version":"3.49.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,10,4]],"date-time":"2013-10-04T00:00:00Z","timestamp":1380844800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1007\/s00380-013-0413-3","type":"journal-article","created":{"date-parts":[[2013,10,3]],"date-time":"2013-10-03T08:55:14Z","timestamp":1380790514000},"page":"629-637","source":"Crossref","is-referenced-by-count":15,"title":["Ischemic heart diseases in Egypt: role of xanthine oxidase system and ischemia-modified albumin"],"prefix":"10.1007","volume":"29","author":[{"given":"Ola Sayed","family":"Ali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanan Muhammad","family":"Abdelgawad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makram Sayed","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehab Refaat","family":"El-Awady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,10,4]]},"reference":[{"issue":"1","key":"413_CR1","first-page":"61","volume":"23","author":"K Aggarwal","year":"2011","unstructured":"Aggarwal K, Seth S, Dahiya K, Aggarwal H, Aggarwal MK (2011) Ischemia modified albumin in patients of cardiac and non-cardiac chest pain. Biomed Res 23(1):61\u201365","journal-title":"Biomed Res"},{"key":"413_CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S1734-1140(09)70002-7","volume":"61","author":"B Ostadal","year":"2009","unstructured":"Ostadal B (2009) The past, the present and the future of experimental research on myocardial ischemia and protection. Pharmacol Rep 61:3\u201312","journal-title":"Pharmacol Rep"},{"key":"413_CR3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2147\/TCRM.S26414","volume":"8","author":"W Almahmeed","year":"2012","unstructured":"Almahmeed W, Arnaout MS, Chettaoui R, Ibrahim M, Kurdi MI, Taher MA, Mancia G (2012) Coronary artery disease in Africa and the Middle East. Ther Clin Risk Manag 8:65\u201372","journal-title":"Ther Clin Risk Manag"},{"issue":"3","key":"413_CR4","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3109\/07388551.2010.527823","volume":"31","author":"A Agarwal","year":"2011","unstructured":"Agarwal A, Banerjee A, Banerjee UC (2011) Xanthine oxidoreductase: a journey from purine metabolism to cardiovascular excitation\u2013contraction coupling. Crit Rev Biotechnol 31(3):264\u2013280","journal-title":"Crit Rev Biotechnol"},{"key":"413_CR5","first-page":"19","volume":"7","author":"S Ma","year":"2012","unstructured":"Ma S, Jin Y, Hu W, Bai F, Xu W, Yu W (2012) Evaluation of ischemia-modified albumin and C-reactive protein in type 2 diabetics with and without ketosis. Biomark Insights 7:19\u201326","journal-title":"Biomark Insights"},{"key":"413_CR6","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1253\/circj.CJ-09-0581","volume":"74","author":"DH Lee","year":"2010","unstructured":"Lee DH, Jeon HK, Park HJ, Shin WS, Lee SW, Youn HJ, Kim CM, Lee HK (2010) Change in ischemia-modified albumin and its clinical significance during exercise stress testing. Circ J 74:484\u2013489","journal-title":"Circ J"},{"key":"413_CR7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/10641950701885147","volume":"27","author":"BB Rijn Van","year":"2008","unstructured":"Van Rijn BB, Franx A, Sikkema JM (2008) Ischemia modified albumin in normal pregnancy and preeclampsia. Hypertens Pregnancy 27:159\u2013167","journal-title":"Hypertens Pregnancy"},{"key":"413_CR8","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000097644","volume":"23","author":"H Abboud","year":"2007","unstructured":"Abboud H, Labreuche J, Meseguer E (2007) Ischemia modified albumin in acute stroke. Cerebrovasc Dis 23:216\u2013220","journal-title":"Cerebrovasc Dis"},{"key":"413_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jcla.20226","volume":"22","author":"LC Cichota","year":"2008","unstructured":"Cichota LC, Moresco RN, Duarte MM (2008) Evaluation of ischemia-modified albumin in anemia associated to chronic kidney disease. J Clin Lab Anal 22:1\u20135","journal-title":"J Clin Lab Anal"},{"key":"413_CR10","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1515\/CCLM.2007.087","volume":"45","author":"J Falkensammer","year":"2007","unstructured":"Falkensammer J, Stojakovic T, Huber K (2007) Serum levels of ischemia-modified albumin in healthy volunteers after exercise-induced calf-muscle ischemia. Clin Chem Lab Med 45:535\u2013540","journal-title":"Clin Chem Lab Med"},{"key":"413_CR11","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.cca.2005.10.020","volume":"366","author":"AR Majed","year":"2006","unstructured":"Majed AR, Curtis AP, Rick WW (2006) Ischemia modified albumin increases after skeletal muscle ischemia during arthroscopic knee surgery. Clin Chim Acta 366:264\u2013268","journal-title":"Clin Chim Acta"},{"key":"413_CR12","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1093\/clinchem\/28.10.2077","volume":"28","author":"R Fossati","year":"1982","unstructured":"Fossati R, Principe L (1982) Serum triglyceride determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 28:2077\u20132080","journal-title":"Clin Chem"},{"key":"413_CR13","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/clinchem\/20.4.470","volume":"20","author":"CC Allain","year":"1974","unstructured":"Allain CC, Poon LS, Clau C, Richmond W, Fu PD (1974) Enzymatic determination of total serum cholesterol. Clin Chem 20:470\u2013475","journal-title":"Clin Chem"},{"issue":"6","key":"413_CR14","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0022-2275(20)42943-8","volume":"11","author":"M Burstein","year":"1970","unstructured":"Burstein M, Scholnick HR, Morfin R (1970) Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res 11(6):583\u2013595","journal-title":"J Lipid Res"},{"key":"413_CR15","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","author":"W Friedewald","year":"1972","unstructured":"Friedewald W, Levy R, Fredrickson D (1972) Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 18:499\u2013502","journal-title":"Clin Chem"},{"key":"413_CR16","doi-asserted-by":"crossref","unstructured":"Schumann G, Bonora R, Ceriotti F, F\u00e9rard G, Ferrero CA, Franck PF, Gella FJ, Hoelzel W, J\u00f8rgensen PJ, Kanno T, Kessner A, Klauke R, Kristiansen N, Lessinger JM, Linsinger TP, Misaki H, Panteghini M, Pauwels J, Schiele F, Schimmel HG, Weidemann G, Siekmann L; International Federation of Clinical Chemistry and Laboratory Medicine (2002) IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 degrees C. International Federation of Clinical Chemistry and Laboratory Medicine. Part 5. Reference procedure for the measurement of catalytic concentration of aspartate aminotransferase. Clin Chem Lab Med 40(7):725\u2013733 (Erratum in Clin Chem Lab Med. 2010;48(5):615\u2013621)","DOI":"10.1515\/CCLM.2002.110"},{"issue":"2","key":"413_CR17","first-page":"87","volume":"40","author":"French Society of Clinical Biology (SFBC)","year":"1982","unstructured":"French Society of Clinical Biology (SFBC) (1982) Soci\u00e9t\u00e9 Fran\u00e7aise de Biologie Clinique. Enzymology Commission. Recommendations. Ann Biol Clin 40(2):87\u2013164","journal-title":"Ann Biol Clin"},{"issue":"6","key":"413_CR18","first-page":"635","volume":"40","author":"G Schumann","year":"2002","unstructured":"Schumann G, Bonora R, Ceriotti F, Clerc-Renaud P, Ferrero CA, F\u00e9rard G, Franck PF, Gella FJ, Hoelzel W, J\u00f8rgensen PJ, Kanno T, Kessne A, Klauker R, Kristiansen N, Lessinger JM, Linsinger TP, Misaki H, Panteghini M, Pauwels J, Schimmel HG, Vialle A, Weidemann G, Siekmann L (2002) IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 degrees C. Part 2. Reference procedure for the measurement of catalytic concentration of creatine kinase. Clin Chem Lab Med 40(6):635\u2013642","journal-title":"Clin Chem Lab Med"},{"issue":"4","key":"413_CR19","first-page":"249","volume":"15","author":"German Society of Clinical Chemistry (DGKC)","year":"1977","unstructured":"German Society of Clinical Chemistry (DGKC) (1977) Recommendation of the German society of clinical chemistry. Standardization of methods for the estimation of enzyme activities in biological fluids: Standard method for the determination of creatine kinase activity. J Clin Chem Clin Biochem 15(4):249\u2013260 (in German)","journal-title":"J Clin Chem Clin Biochem"},{"key":"413_CR20","first-page":"208","volume-title":"Clinical laboratory diagnostics. Use and assessment of clinical laboratory results","author":"L Thomas","year":"1998","unstructured":"Thomas L (1998) Clinical laboratory diagnostics. Use and assessment of clinical laboratory results, 1st edn. TH-Books Verlagsgesellschaft, Frankfurt\/Main, pp 208\u2013214","edition":"1"},{"key":"413_CR21","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/0003-2697(74)90175-4","volume":"62","author":"S Hashimoto","year":"1974","unstructured":"Hashimoto S (1974) A new spectrophotometric assay method of xanthine oxidase in crude tissue homogenate. Anal Biochem 62:426\u2013435","journal-title":"Anal Biochem"},{"key":"413_CR22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0736-4679(00)00255-9","volume":"19","author":"D Bar-Or","year":"2000","unstructured":"Bar-Or D, Lau E, Winkler J (2000) A novel assay for cobalt\u2013albumin binding and its potential as a marker for myocardial ischemia\u2014a preliminary report. J Emerg Med 19:311\u2013315","journal-title":"J Emerg Med"},{"key":"413_CR23","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1210\/jc.2009-1592","volume":"95","author":"M Gottlieb","year":"2010","unstructured":"Gottlieb M, Cruz I, Duarte M, Moresco R, Wiehe M, Schwanke C, Bodanese L (2010) Associations among metabolic syndrome, ischemia, inflammatory, oxidatives, and lipids biomarkers. J Clin Endocrinol Metab 95:586\u2013591","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"413_CR24","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/BF02913321","volume":"22","author":"R Raghuvanshi","year":"2007","unstructured":"Raghuvanshi R, Kaul A, Bhakuni P, Mishra A, Misra M (2007) Xanthine oxidase as a marker of myocardial infarction. Indian J Clin Biochem 22(2):90\u201392","journal-title":"Indian J Clin Biochem"},{"key":"413_CR25","first-page":"759","volume":"56","author":"M Nadkar","year":"2008","unstructured":"Nadkar M, Jain V (2008) Serum uric acid in acute myocardial infarction. J Assoc Physicians India 56:759\u2013762","journal-title":"J Assoc Physicians India"},{"key":"413_CR26","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1253\/circj.CJ-10-0952","volume":"75","author":"MH Bae","year":"2011","unstructured":"Bae MH, Lee JH, Lee SH, Park SH, Yang DH, Park HS, Cho Y, Jun JE, Chae SC (2011) Serum uric acid as an independent and incremental prognostic marker in addition to N-terminal pro-B-type natriuretic peptide in patients with acute myocardial infarction. Circ J 75:1440\u20131447","journal-title":"Circ J"},{"key":"413_CR27","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1124\/pr.58.1.6","volume":"58","author":"P Pacher","year":"2006","unstructured":"Pacher P, Nivorozhkin A, Szab\u00f3 C (2006) Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev 58:87\u2013114","journal-title":"Pharmacol Rev"},{"key":"413_CR28","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.3748\/wjg.14.2832","volume":"14","author":"PG Liu","year":"2008","unstructured":"Liu PG, He SQ, Zhang YH, Wu J (2008) Protective effects of apocynin and allopurinol on ischemia\/reperfusion-induced liver injury in mice. World J Gastroenterol 14:2832\u20132837","journal-title":"World J Gastroenterol"},{"key":"413_CR29","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1093\/eurjhf\/hfn003","volume":"11","author":"J Xiao","year":"2009","unstructured":"Xiao J, She Q, Wang Y, Luo K, Yin Y, Hu R, Huang K (2009) Effect of allopurinol on cardiomyocyte apoptosis in rats after myocardial infarction. Eur J Heart Fail 11:20\u201327","journal-title":"Eur J Heart Fail"},{"key":"413_CR30","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/BF01907096","volume":"82","author":"M Muxfeldt","year":"1987","unstructured":"Muxfeldt M, Schaper W (1987) The activity of xanthine oxidase in heart of pigs, guinea pigs, rabbits, rats and humans. Basic Res Cardiol 82:486\u2013492","journal-title":"Basic Res Cardiol"},{"key":"413_CR31","first-page":"H699","volume":"253","author":"LA Hernandez","year":"1987","unstructured":"Hernandez LA, Grishamn MB, Twohig B, Arfors KE, Harlan JM, Granger DN (1987) Role of neutrophils in ischemia-reperfusion induced microvascular injury. Am J Physiol 253:H699\u2013H703","journal-title":"Am J Physiol"},{"issue":"1","key":"413_CR32","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3904\/kjim.2010.25.1.21","volume":"25","author":"H Lim","year":"2010","unstructured":"Lim H, Kim S, Kim E, Kim J, Rha S, Seo H, Park C (2010) Clinical value of serum uric acid in patients with suspected coronary artery disease. Korean J Intern Med 25(1):21\u201326","journal-title":"Korean J Intern Med"},{"key":"413_CR33","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1111\/j.1523-1755.2005.00273.x","volume":"67","author":"U Khosla","year":"2005","unstructured":"Khosla U, Zharikov S, Finch J (2005) Hyperuricemia induces endothelial dysfunction and vasoconstriction. Kidney Int 67:1739\u20131742","journal-title":"Kidney Int"},{"key":"413_CR34","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.amjcard.2007.02.065","volume":"100","author":"C Ruggiero","year":"2007","unstructured":"Ruggiero C, Cherubini A, Miller E (2007) Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 years. Am J Cardiol 100:115\u2013121","journal-title":"Am J Cardiol"},{"issue":"3","key":"413_CR35","first-page":"186","volume":"5","author":"A Iliesiu","year":"2010","unstructured":"Iliesiu A, Campeanu A, Dusceac D (2010) Serum uric acid and cardiovascular disease. Maedica (Buchar) 5(3):186\u2013192","journal-title":"Maedica (Buchar)"},{"issue":"6","key":"413_CR36","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s00380-010-0114-0","volume":"26","author":"J Chek","year":"2011","unstructured":"Chek J, Dusek J, Stasek J, Vojacek J, Bis J, Ulrychova M, Tichy M, Tomko T, Bukac J (2011) Role of ischemia-modified albumin in estimating the extent and scope of cardiac ischemia in patients with ST elevation myocardial infarction. Heart Vessels 26(6):622\u2013627","journal-title":"Heart Vessels"},{"issue":"1","key":"413_CR37","first-page":"25","volume":"49","author":"J Dawie","year":"2011","unstructured":"Dawie J, Chawla R, Worku Y, Azazh A (2011) Diagnosis of ischemic heart disease using CK-MB, troponin-I and ischemia modified albumin. Ethiop Med J 49(1):25\u201333","journal-title":"Ethiop Med J"},{"key":"413_CR38","first-page":"59","volume":"18","author":"AJ Safi","year":"2004","unstructured":"Safi AJ, Mahmood R, Khan MA, Haq A (2004) Association of serum uric acid with type II diabetes mellitus. J Postgrad Med Inst 18:59\u201363","journal-title":"J Postgrad Med Inst"},{"issue":"1","key":"413_CR39","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1136\/hrt.2004.049643","volume":"92","author":"D Roy","year":"2006","unstructured":"Roy D, Quiles J, Gaze DC, Collinson P, Kaski JC, Baxter GF (2006) Role of reactive oxygen species on the formation of the novel diagnostic marker ischaemia modified albumin. Heart 92(1):113\u2013114","journal-title":"Heart"},{"issue":"1","key":"413_CR40","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00380-010-0029-9","volume":"26","author":"MD Bagatini","year":"2011","unstructured":"Bagatini MD, Martins CC, Battisti V, Gasparetto D, da Rosa CS, Spanevello RM, Ahmed M, Schmatz R, Schetinger MR, Morsch VM (2011) Oxidative stress versus antioxidant defenses in patients with acute myocardial infarction. Heart Vessels 26(1):55\u201363","journal-title":"Heart Vessels"},{"key":"413_CR41","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.freeradbiomed.2009.11.012","volume":"48","author":"EE Kelley","year":"2010","unstructured":"Kelley EE, Khoo NKH, Hundley NJ, Malik UZ, Freeman BA, Tarpey MM (2010) Hydrogen peroxide is the major oxidant product of xanthine oxidase. Free Radic Biol Med 48:493\u2013498","journal-title":"Free Radic Biol Med"},{"key":"413_CR42","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1042\/bj2430055","volume":"243","author":"B Bolann","year":"1987","unstructured":"Bolann B, Ulvik RJ (1987) Release of iron from ferritin by xanthine oxidase; role of the superoxide radical. Biochem J 243:55\u201359","journal-title":"Biochem J"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-013-0413-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00380-013-0413-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-013-0413-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T20:09:27Z","timestamp":1646683767000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00380-013-0413-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,4]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["413"],"URL":"https:\/\/doi.org\/10.1007\/s00380-013-0413-3","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"value":"0910-8327","type":"print"},{"value":"1615-2573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,4]]}}}