{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T09:54:28Z","timestamp":1769766868796,"version":"3.49.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T00:00:00Z","timestamp":1469577600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1007\/s00380-016-0881-3","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T11:53:42Z","timestamp":1469620422000},"page":"352-358","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["T wave amplitude in lead aVR as a novel diagnostic marker for cardiac sarcoidosis"],"prefix":"10.1007","volume":"32","author":[{"given":"Yoshihiro","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Konno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toyonobu","family":"Tsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Sakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Furusho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Takamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Yamagishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenshi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,7,27]]},"reference":[{"key":"881_CR1","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1161\/01.CIR.58.6.1204","volume":"58","author":"KJ Silverman","year":"1978","unstructured":"Silverman KJ, Hutchins GM, Bulkley BH (1978) Cardiac sarcoid: a clinicopathologic study of 84 unselected patients with systemic sarcoidosis. Circulation 58:1204\u20131211","journal-title":"Circulation"},{"key":"881_CR2","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jcmg.2012.10.021","volume":"6","author":"S Greulich","year":"2013","unstructured":"Greulich S, Deluigi CC, Gloekler S, Wahl A, Z\u00fcrn C, Kramer U, Nothnagel D, B\u00fcltel H, Schumm J, Gr\u00fcn S, Ong P, Wagner A, Schneider S, Nassenstein K, Gawaz M, Sechtem U, Bruder O, Mahrholdt H (2013) CMR imaging predicts death and other adverse events in suspected cardiac sarcoidosis. JACC Cardiovasc Imaging 6:501\u2013511","journal-title":"JACC Cardiovasc Imaging"},{"key":"881_CR3","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1053\/j.semnuclmed.2013.06.007","volume":"43","author":"D Sobic-Saranovic","year":"2013","unstructured":"Sobic-Saranovic D, Artiko V, Obradovic V (2013) FDG PET imaging in sarcoidosis. Semin Nucl Med 43:404\u2013411","journal-title":"Semin Nucl Med"},{"key":"881_CR4","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1007\/s00380-015-0670-4","volume":"31","author":"A Funada","year":"2016","unstructured":"Funada A, Kanzaki H, Noguchi T, Morita Y, Sugano Y, Ohara T, Hasegawa T, Hashimura H, Ishibashi-Ueda H, Kitakaze M, Yasuda S, Ogawa H, Anzai T (2016) Prognostic significance of late gadolinium enhancement quantification in cardiac magnetic resonance imaging of hypertrophic cardiomyopathy with systolic dysfunction. Heart Vessels 31:758\u2013770","journal-title":"Heart Vessels"},{"key":"881_CR5","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-016-0815-0","author":"S Ishii","year":"2016","unstructured":"Ishii S, Inomata T, Fujita T, Iida Y, Nabeta T, Yanagisawa T, Naruke T, Mizutani T, Koitabashi T, Takeuchi I, Ako J (2016) Clinical significance of endomyocardial biopsy in conjunction with cardiac magnetic resonance imaging to predict left ventricular reverse remodeling in idiopathic dilated cardiomyopathy. Heart Vessels. doi: 10.1007\/s00380-016-0815-0","journal-title":"Heart Vessels"},{"key":"881_CR6","first-page":"89","volume":"27","author":"T Tsuda","year":"2006","unstructured":"Tsuda T, Ishihara M, Okamoto H, Ohara K, Oritsu M, Sugiura K, Shima K, Takenaka S, Tachibana T (2006) Diagnostic standard and guideline for sarcoidosis-2006. Jpn J Sacoidosis Granulomatous Disord 27:89\u2013102\u00a0[in Japanese]","journal-title":"Jpn J Sacoidosis Granulomatous Disord"},{"key":"881_CR7","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1111\/j.1540-8167.2011.02099.x","volume":"22","author":"JL Schuller","year":"2011","unstructured":"Schuller JL, Olson MD, Zipse MM, Schneider PM, Aleong RG, Wienberger HD, Varosy PD, Sauer WH (2011) Electrocardiographic characteristics in patients with pulmonary sarcoidosis indicating cardiac involvement. J Cardiovasc Electrophysiol 22:1243\u20131248","journal-title":"J Cardiovasc Electrophysiol"},{"key":"881_CR8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ahj.2007.03.037","volume":"154","author":"AT Yan","year":"2007","unstructured":"Yan AT, Yan RT, Kennelly BM, Anderson FA, Budaj A, L\u00f3pez-Send\u00f3n J, Brieger D, Allegrone J, Steg G, Goodman SG, Investigators G (2007) Relationship of ST elevation in lead aVR with angiographic findings and outcome in non-ST elevation acute coronary syndromes. Am Heart J 154:71\u201378","journal-title":"Am Heart J"},{"key":"881_CR9","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.hrthm.2007.04.017","volume":"4","author":"MA Babai Bigi","year":"2007","unstructured":"Babai Bigi MA, Aslani A, Shahrzad S (2007) aVR sign as a risk factor for life-threatening arrhythmic events in patients with Brugada syndrome. Heart Rhythm 4:1009\u20131012","journal-title":"Heart Rhythm"},{"key":"881_CR10","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s00380-011-0193-6","volume":"27","author":"K Torigoe","year":"2012","unstructured":"Torigoe K, Tamura A, Kawano Y, Shinozaki K, Kotoku M, Kadota J (2012) Upright T waves in lead aVR are associated with cardiac death or hospitalization for heart failure in patients with a prior myocardial infarction. Heart Vessels 27:548\u2013552","journal-title":"Heart Vessels"},{"key":"881_CR11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1542-474X.2008.00210.x","volume":"13","author":"SY Tan","year":"2008","unstructured":"Tan SY, Engel G, Myers J, Sandri M, Froelicher VF (2008) The prognostic value of T wave amplitude in lead aVR in males. Ann Noninvasive Electrocardiol 13:113\u2013119","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"881_CR12","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/s10157-015-1100-8","volume":"19","author":"A Jaroszy\u0144ski","year":"2015","unstructured":"Jaroszy\u0144ski A, Jaroszy\u0144ska A, Siebert J, D\u0105browski W, Niedzia\u0142ek J, Bednarek-Skublewska A, Zapolski T, Wysoki\u0144ski A, Za\u0142uska W, Ksi\u0105\u017cek A, Schlegel TT (2015) The prognostic value of positive T-wave in lead aVR in hemodialysis patients. Clin Exp Nephrol 19:1157\u20131164","journal-title":"Clin Exp Nephrol"},{"key":"881_CR13","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1161\/CIRCULATIONAHA.105.595892","volume":"113","author":"MK Das","year":"2006","unstructured":"Das MK, Khan B, Jacob S, Kumar A, Mahenthiran J (2006) Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease. Circulation 113:2495\u20132501","journal-title":"Circulation"},{"key":"881_CR14","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/CIRCEP.107.763284","volume":"1","author":"MK Das","year":"2008","unstructured":"Das MK, Suradi H, Maskoun W, Michael MA, Shen C, Peng J, Dandamudi G, Mahenthiran J (2008) Fragmented wide QRS on a 12-lead ECG: a sign of myocardial scar and poor prognosis. Circ Arrhythm Electrophysiol 1:258\u2013268","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"881_CR15","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jacc.2015.10.076","volume":"67","author":"Y Biton","year":"2016","unstructured":"Biton Y, Goldenberg I, Kutyifa V, Baman JR, Solomon S, Moss AJ, Szepietowska B, McNitt S, Polonsky B, Zareba W, Barsheshet A (2016) Relative wall thickness and the risk for ventricular tachyarrhythmias in patients with left ventricular dysfunction. J Am Coll Cardiol 67:303\u2013312","journal-title":"J Am Coll Cardiol"},{"key":"881_CR16","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","volume":"3","author":"WJ Youden","year":"1950","unstructured":"Youden WJ (1950) Index for rating diagnostic tests. Cancer 3:32\u201335","journal-title":"Cancer"},{"key":"881_CR17","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s00259-015-3181-8","volume":"43","author":"H Ohira","year":"2016","unstructured":"Ohira H, Birnie DH, Pena E, Bernick J, Mc Ardle B, Leung E, Wells GA, Yoshinaga K, Tsujino I, Sato T, Manabe O, Oyama-Manabe N, Nishimura M, Tamaki N, Dick A, Dennie C, Klein R, Renaud J, deKemp RA, Ruddy TD, Chow BJ, Davies R, Hessian R, Liu P, Beanlands RS, Nery PB (2016) Comparison of (18)F-fluorodeoxyglucose positron emission tomography (FDG PET) and cardiac magnetic resonance (CMR) in corticosteroid-naive patients with conduction system disease due to cardiac sarcoidosis. Eur J Nucl Med Mol Imaging 43:259\u2013269","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"881_CR18","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.hrthm.2015.06.032","volume":"12","author":"M Orii","year":"2015","unstructured":"Orii M, Hirata K, Tanimoto T, Ota S, Shiono Y, Yamano T, Matsuo Y, Ino Y, Yamaguchi T, Kubo T, Tanaka A, Akasaka T (2015) Comparison of cardiac MRI and (18)F-FDG positron emission tomography manifestations and regional response to corticosteroid therapy in newly diagnosed cardiac sarcoidosis with complete heart block. Heart Rhythm 12:2477\u20132485","journal-title":"Heart Rhythm"},{"key":"881_CR19","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jjcc.2010.12.002","volume":"57","author":"K Shinozaki","year":"2011","unstructured":"Shinozaki K, Tamura A, Kadota J (2011) Associations of positive T wave in lead aVR with hemodynamic, coronary, and left ventricular angiographic findings in anterior wall old myocardial infarction. J Cardiol 57:160\u2013164","journal-title":"J Cardiol"},{"key":"881_CR20","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1164\/ajrccm.164.10.2104046","volume":"164","author":"RP Baughman","year":"2001","unstructured":"Baughman RP, Teirstein AS, Judson MA, Rossman MD, Yeager H, Bresnitz EA, DePalo L, Hunninghake G, Iannuzzi MC, Johns CJ, McLennan G, Moller DR, Newman LS, Rabin DL, Rose C, Rybicki B, Weinberger SE, Terrin ML, Knatterud GL, Cherniak R, group CCESoSAr (2001) Clinical characteristics of patients in a case control study of sarcoidosis. Am J Respir Crit Care Med 164:1885\u20131889","journal-title":"Am J Respir Crit Care Med"},{"key":"881_CR21","first-page":"149","volume":"16","author":"GW Hunninghake","year":"1999","unstructured":"Hunninghake GW, Costabel U, Ando M, Baughman R, Cordier JF, du Bois R, Eklund A, Kitaichi M, Lynch J, Rizzato G, Rose C, Selroos O, Semenzato G, Sharma OP (1999) ATS\/ERS\/WASOG statement on sarcoidosis. American Thoracic Society\/European Respiratory Society\/World Association of Sarcoidosis and other Granulomatous disorders. Sarcoidosis Vasc Diffuse Lung Dis 16:149\u2013173","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"881_CR22","first-page":"372","volume":"43","author":"K Iwai","year":"1993","unstructured":"Iwai K, Tachibana T, Takemura T, Matsui Y, Kitaichi M, Kawabata Y (1993) Pathological studies on sarcoidosis autopsy. I. Epidemiological features of 320 cases in Japan. Acta Pathol Jpn 43:372\u2013376","journal-title":"Acta Pathol Jpn"},{"key":"881_CR23","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/j.ijcard.2012.04.064","volume":"167","author":"MS Ahn","year":"2013","unstructured":"Ahn MS, Kim JB, Joung B, Lee MH, Kim SS (2013) Prognostic implications of fragmented QRS and its relationship with delayed contrast-enhanced cardiovascular magnetic resonance imaging in patients with non-ischemic dilated cardiomyopathy. Int J Cardiol 167:1417\u20131422","journal-title":"Int J Cardiol"},{"key":"881_CR24","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1007\/s11886-013-0370-6","volume":"15","author":"H Skali","year":"2013","unstructured":"Skali H, Schulman AR, Dorbala S (2013) 18F-FDG PET\/CT for the assessment of myocardial sarcoidosis. Curr Cardiol Rep 15:352","journal-title":"Curr Cardiol Rep"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-016-0881-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00380-016-0881-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-016-0881-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-016-0881-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T19:19:26Z","timestamp":1498331966000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00380-016-0881-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,27]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["881"],"URL":"https:\/\/doi.org\/10.1007\/s00380-016-0881-3","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"value":"0910-8327","type":"print"},{"value":"1615-2573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,27]]}}}