{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T20:41:17Z","timestamp":1769114477737,"version":"3.49.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T00:00:00Z","timestamp":1535068800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1007\/s00380-018-1245-y","type":"journal-article","created":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T07:17:00Z","timestamp":1535095020000},"page":"259-267","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Very long-term follow-up data of non-ischemic idiopathic dilated cardiomyopathy after beta-blocker therapy: recurrence of left ventricular dysfunction and predictive value of 123I-metaiodobenzylguanidine scintigraphy"],"prefix":"10.1007","volume":"34","author":[{"given":"Shunsuke","family":"Nishimura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chisato","family":"Izumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Himura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maiko","family":"Kuroda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Amano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Harita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suguru","family":"Nishiuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiro","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yodo","family":"Tamaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soichiro","family":"Enomoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihisa","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,8,24]]},"reference":[{"issue":"16","key":"1245_CR1","doi-asserted-by":"publisher","first-page":"e147","DOI":"10.1016\/j.jacc.2013.05.019","volume":"62","author":"CW Yancy","year":"2013","unstructured":"Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, Johnson MR, Kasper EK, Levy WC, Masoudi FA, McBride PE, McMurray JJ, Mitchell JE, Peterson PN, Riegel B, Sam F, Stevenson LW, Tang WH, Tsai EJ, Wilkoff BL, American College of Cardiology Foundation; American Heart Association Task Force on Practice Guidelines (2013) 2013 ACCF\/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 62(16):e147\u2013e239","journal-title":"J Am Coll Cardiol"},{"issue":"23","key":"1245_CR2","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1093\/eurheartj\/ehv727","volume":"37","author":"YM Pinto","year":"2016","unstructured":"Pinto YM, Elliott PM, Arbustini E, Adler Y, Anastasakis A, B\u00f6hm M, Duboc D, Gimeno J, de Groote P, Imazio M, Heymans S, Klingel K, Komajda M, Limongelli G, Linhart A, Mogensen J, Moon J, Pieper PG, Seferovic PM, Schueler S, Zamorano JL, Caforio AL, Charron P (2016) Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases. Eur Heart J 37(23):1850\u20131858","journal-title":"Eur Heart J"},{"issue":"9169","key":"1245_CR3","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1016\/S0140-6736(99)04440-2","volume":"353","author":"MERIT-HF Study Group","year":"1999","unstructured":"MERIT-HF Study Group (1999) Effect of metoprolol CR\/XL in chronic heart failure: Metoprolol CR\/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 353(9169):2001\u20132007","journal-title":"Lancet"},{"issue":"21","key":"1245_CR4","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1056\/NEJM199605233342101","volume":"334","author":"M Packer","year":"1996","unstructured":"Packer M, Bristow MR, Cohn JN, Colucci WS, Fowler MB, Gilbert EM, Shusterman NH (1996) The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group. N Engl J Med 334(21):1349\u20131355","journal-title":"N Engl J Med"},{"issue":"5","key":"1245_CR5","first-page":"523","volume":"24","author":"S Fukuoka","year":"1997","unstructured":"Fukuoka S, Hayashida K, Hirose Y, Shimotsu Y, Ishida Y, Kakuchi H, Eto T (1997) Use of iodine-123 metaiodobenzylguanidine myocardial imaging to predict the effectiveness of beta-blocker therapy in patients with dilated cardiomyopathy. Eur J Nucl Med 24(5):523\u2013529","journal-title":"Eur J Nucl Med"},{"issue":"8","key":"1245_CR6","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1093\/eurheartj\/ehm048","volume":"28","author":"S Kasama","year":"2007","unstructured":"Kasama S, Toyama T, Hatori T, Sumino H, Kumakura H, Takayama Y, Ichikawa S, Suzuki T, Kurabayashi M (2007) Evaluation of cardiac sympathetic nerve activity and left ventricular remodelling in patients with dilated cardiomyopathy on the treatment containing carvedilol. Eur Heart J 28(8):989\u2013995","journal-title":"Eur Heart J"},{"issue":"4","key":"1245_CR7","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1002\/clc.22243","volume":"37","author":"JS Park","year":"2014","unstructured":"Park JS, Kim JW, Seo KW, Choi BJ, Choi SY, Yoon MH, Hwang GS, Tahk SJ, Shin JH (2014) Recurrence of left ventricular dysfunction in patients with restored idiopathic dilated cardiomyopathy. Clin Cardiol 37(4):222\u2013226","journal-title":"Clin Cardiol"},{"issue":"6","key":"1245_CR8","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1016\/j.amjcard.2014.06.021","volume":"114","author":"A Gupta","year":"2014","unstructured":"Gupta A, Goyal P, Bahl A (2014) Frequency of recovery and relapse in patients with nonischemic dilated cardiomyopathy on guideline-directed medical therapy. Am J Cardiol 114(6):883\u2013889","journal-title":"Am J Cardiol"},{"issue":"13","key":"1245_CR9","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1016\/j.jacc.2010.11.030","volume":"57","author":"M Merlo","year":"2011","unstructured":"Merlo M, Pyxaras SA, Pinamonti B, Barbati G, Di Lenarda A, Sinagra G (2011) Prevalence and prognostic significance of left ventricular reverse remodeling in dilated cardiomyopathy receiving tailored medical treatment. J Am Coll Cardiol 57(13):1468\u20131476","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"1245_CR10","first-page":"349","volume":"21","author":"DM Wieland","year":"1980","unstructured":"Wieland DM, Wu J, Brown LE, Mangner TJ, Swanson DP, Beierwaltes WH (1980) Radiolabeled adrenergic neuron-blocking agents: adrenomedullary imaging with [131I]iodobenzylguanidine. J Nucl Med 21(4):349\u2013353","journal-title":"J Nucl Med"},{"issue":"5","key":"1245_CR11","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1016\/0735-1097(88)92608-3","volume":"12","author":"J Schofer","year":"1988","unstructured":"Schofer J, Spielmann R, Schuchert A, Weber K, Schluter M (1988) Iodine-123 meta-iodobenzylguanidine scintigraphy: a noninvasive method to demonstrate myocardial adrenergic nervous system disintegrity in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 12(5):1252\u20131258","journal-title":"J Am Coll Cardiol"},{"issue":"20","key":"1245_CR12","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1016\/j.jacc.2010.01.014","volume":"55","author":"AF Jacobson","year":"2010","unstructured":"Jacobson AF, Senior R, Cerqueira MD, Wong ND, Thomas GS, Lopez VA, Agostini D, Weiland F, Chandna H, Narula J, ADMIRE-HF Investigators (2010) Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study. J Am Coll Cardiol 55(20):2212\u20132221","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"1245_CR13","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1016\/j.amjcard.2008.01.030","volume":"101","author":"Y Kamiyoshi","year":"2008","unstructured":"Kamiyoshi Y, Yazaki Y, Urushibata K, Koizumu T, Kasai H, Izawa A, Kinoshita O, Hongo M, Ikeda U (2008) Risk stratification assessed by combined lung and heart iodine-123 metaiodobenzylguanidine uptake in patients with idiopathic dilated cardiomyopathy. Am J Cardiol 101(10):1482\u20131486","journal-title":"Am J Cardiol"},{"issue":"2","key":"1245_CR14","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1253\/circj.CJ-12-0507","volume":"77","author":"JO Choi","year":"2013","unstructured":"Choi JO, Kim EY, Lee GY, Lee SC, Park SW, Kim DK, Oh JK, Jeon ES (2013) Predictors of left ventricular reverse remodeling and subsequent outcome in nonischemic dilated cardiomyopathy. Circ J 77(2):462\u2013469","journal-title":"Circ J"},{"issue":"4","key":"1245_CR15","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1007\/s00380-015-0648-2","volume":"31","author":"Y Ikeda","year":"2016","unstructured":"Ikeda Y, Inomata T, Iida Y, Iwamoto-Ishida M, Nabeta T, Ishii S, Sato T, Yanagisawa T, Mizutani T, Naruke T, Koitabashi T, Takeuchi I, Nishii M, Ako J (2016) Time course of left ventricular reverse remodeling in response to pharmacotherapy: clinical implication for heart failure prognosis in patients with idiopathic dilated cardiomyopathy. Heart Vessels 31(4):545\u2013554","journal-title":"Heart Vessels"},{"issue":"12","key":"1245_CR16","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1007\/s00380-016-0815-0","volume":"31","author":"S Ishii","year":"2016","unstructured":"Ishii S, Inomata T, Fujita T, Iida Y, Ikeda Y, Nabeta T, Yanagisawa T, Naruke T, Mizutani T, Koitabashi T, Takeuchi I, Ako J (2016) Clinical significance of endomyocardial biopsy in conjunction with cardiac magnetic resonance imaging to predict left ventricular reverse remodeling in idiopathic dilated cardiomyopathy. Heart Vessels 31(12):1960\u20131968","journal-title":"Heart Vessels"},{"issue":"5","key":"1245_CR17","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.jacc.2008.10.025","volume":"53","author":"S Tamaki","year":"2009","unstructured":"Tamaki S, Yamada T, Okuyama Y, Morita T, Sanada S, Tsukamoto Y, Masuda M, Okuda K, Iwasaki Y, Yasui T, Hori M, Fukunami M (2009) Cardiac iodine-123 metaiodobenzylguanidine imaging predicts sudden cardiac death independently of left ventricular ejection fraction in patients with chronic heart failure and left ventricular systolic dysfunction: results from a comparative study with signal-averaged electrocardiogram, heart rate variability, and QT dispersion. J Am Coll Cardiol 53(5):426\u2013435","journal-title":"J Am Coll Cardiol"},{"issue":"13","key":"1245_CR18","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1053\/euhj.2000.2407","volume":"22","author":"HP Brunner-La Rocca","year":"2001","unstructured":"Brunner-La Rocca HP, Esler MD, Jennings GL, Kaye DM (2001) Effect of cardiac sympathetic nervous activity on mode of death in congestive heart failure. Eur Heart J 22(13):1136\u20131143","journal-title":"Eur Heart J"},{"issue":"4","key":"1245_CR19","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1007\/s12574-009-0022-4","volume":"7","author":"K Lee","year":"2009","unstructured":"Lee K, Daimon M, Kuwabara Y, Hasegawa R, Toyoda T, Sekine T, Kawata T, Komuro I (2009) Prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy: comparison of 123I-MIBG scintigraphy and low-dose dobutamine stress echocardiography. J Echocardiogr 7(4):74\u201379","journal-title":"J Echocardiogr"},{"issue":"4","key":"1245_CR20","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1067\/mhj.2001.112783","volume":"141","author":"J Yamazaki","year":"2001","unstructured":"Yamazaki J, Muto H, Kabano T, Yamashina S, Nanjo S, Inoue A (2001) Evaluation of beta-blocker therapy in patients with dilated cardiomyopathy\u2014clinical meaning of iodine 123-metaiodobenzylguanidine myocardial single-photon emission computed tomography. Am Heart J 141(4):645\u2013652","journal-title":"Am Heart J"},{"issue":"6","key":"1245_CR21","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1111\/j.1525-1497.2004.30016.x","volume":"19","author":"T Morimoto","year":"2004","unstructured":"Morimoto T, Gandhi TK, Fiskio JM, Seger AC, So JW, Cook EF, Fukui T, Bates DW (2004) Development and validation of a clinical prediction rule for angiotensin-converting enzyme inhibitor-induced cough. J Gen Intern Med 19(6):684\u2013691","journal-title":"J Gen Intern Med"},{"issue":"12","key":"1245_CR22","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1253\/circj.CJ-08-0323","volume":"72","author":"N Kawashiro","year":"2008","unstructured":"Kawashiro N, Kasanuki H, Ogawa H, Matsuda N, Hagiwara N (2008) Clinical characteristics and outcome of hospitalized patients with congestive heart failure: results of the HIJC-HF registry. Circ J 72(12):2015\u20132020","journal-title":"Circ J"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00380-018-1245-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-018-1245-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-018-1245-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T22:07:41Z","timestamp":1566943661000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00380-018-1245-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,24]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["1245"],"URL":"https:\/\/doi.org\/10.1007\/s00380-018-1245-y","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"value":"0910-8327","type":"print"},{"value":"1615-2573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,24]]},"assertion":[{"value":"1 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}