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SI reports receiving grant from Japan Society for the Promotion of Science, outside the submitted work. MK reports grants from Japanese government, grants from Japan Heart Foundation, grants from Japan Agency for Medical Research and Development, personal fees from Daiichi-Sankyo, personal fees from Pfizer, grants and personal fees from Ono, personal fees from Bayer, grants and personal fees from Novartis, grants and personal fees from Boehringer, grants and personal fees from Tanabe-Mitsubishi, personal fees from Japan Medical Data Center, grants and personal fees from Takeda, grants and personal fees from AstraZeneca, outside the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}