{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:58:36Z","timestamp":1788483516351,"version":"build-2803163510"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1007\/s00380-022-02070-7","type":"journal-article","created":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:02:38Z","timestamp":1652140958000},"page":"1719-1727","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Systemic arterial pulsatility index (SAPi) predicts adverse outcomes in advanced heart failure patients"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6451-2118","authenticated-orcid":false,"given":"Sula","family":"Mazimba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hunter","family":"Mwansa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadijah","family":"Breathett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarred E.","family":"Strickling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kajal","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coleen","family":"McNamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishaki","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Younghoon","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephine","family":"Lamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Tallaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salpy","family":"Pamboukian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mwenya","family":"Mubanga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jashanjeet","family":"Matharoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Salerno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Mwansa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth C.","family":"Bilchick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"issue":"1","key":"2070_CR1","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.cardfail.2017.07.001","volume":"24","author":"KC Bilchick","year":"2018","unstructured":"Bilchick KC, Mejia-Lopez E, McCullough P, Breathett K, Kennedy JL, Tallaj J, Bergin J, Pamboukian S, Abuannadi M, Mazimba S (2018) Clinical impact of changes in hemodynamic indices of contractile function during treatment of acute decompensated heart failure. J Card Fail 24(1):43\u201350","journal-title":"J Card Fail"},{"issue":"2","key":"2070_CR2","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1161\/01.RES.19.2.364","volume":"19","author":"JW Covell","year":"1966","unstructured":"Covell JW, Ross J Jr, Sonnenblick EH, Braunwald E (1966) Comparison of the force-velocity relation and the ventricular function curve as measures of the contractile state of the intact heart. Circ Res 19(2):364\u2013372","journal-title":"Circ Res"},{"issue":"1","key":"2070_CR3","doi-asserted-by":"publisher","first-page":"12","DOI":"10.15420\/cfr.2017:4:2","volume":"3","author":"JA Chirinos","year":"2017","unstructured":"Chirinos JA, Sweitzer N (2017) Ventricular\u2013arterial coupling in chronic heart failure. Card Fail Rev 3(1):12\u201318","journal-title":"Card Fail Rev"},{"issue":"3","key":"2070_CR4","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.ccl.2011.06.004","volume":"29","author":"BA Borlaug","year":"2011","unstructured":"Borlaug BA, Kass DA (2011) Ventricular\u2013vascular interaction in heart failure. Cardiol Clin 29(3):447\u2013459","journal-title":"Cardiol Clin"},{"issue":"1","key":"2070_CR5","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1161\/01.HYP.0000168053.34306.d4","volume":"46","author":"DA Kass","year":"2005","unstructured":"Kass DA (2005) Ventricular arterial stiffening: integrating the pathophysiology. Hypertension 46(1):185\u2013193","journal-title":"Hypertension"},{"issue":"9","key":"2070_CR6","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1097\/00004872-199509000-00002","volume":"13","author":"N Westerhof","year":"1995","unstructured":"Westerhof N, O\u2019Rourke MF (1995) Haemodynamic basis for the development of left ventricular failure in systolic hypertension and for its logical therapy. J Hypertens 13(9):943\u2013952","journal-title":"J Hypertens"},{"issue":"43","key":"2070_CR7","doi-asserted-by":"publisher","first-page":"3847","DOI":"10.1093\/eurheartj\/ehy346","volume":"39","author":"T Weber","year":"2018","unstructured":"Weber T, Chirinos JA (2018) Pulsatile arterial haemodynamics in heart failure. Eur Heart J 39(43):3847\u20133854","journal-title":"Eur Heart J"},{"key":"2070_CR8","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.ijcard.2015.04.183","volume":"190","author":"S Parragh","year":"2015","unstructured":"Parragh S, Hametner B, Bachler M, Kellermair J, Eber B, Wassertheurer S, Weber T (2015) Determinants and covariates of central pressures and wave reflections in systolic heart failure. Int J Cardiol 190:308\u2013314","journal-title":"Int J Cardiol"},{"issue":"12","key":"2070_CR9","first-page":"892","volume":"5","author":"G Schillaci","year":"2004","unstructured":"Schillaci G, Di Luzio S, Coluccini M, Gonzini L, Porcu M, Pozzar F, Maggioni AP, Italian Network of Congestive Heart Failure Registry (2004) A low pulse pressure is an independent predictor of mortality in heart failure: data from a large nationwide cardiology database (IN-CHF Registry). Ital Heart J 5(12):892\u2013898","journal-title":"Ital Heart J"},{"issue":"4","key":"2070_CR10","doi-asserted-by":"publisher","first-page":"315","DOI":"10.2459\/JCM.0b013e328365b51e","volume":"15","author":"CJ Petrie","year":"2014","unstructured":"Petrie CJ, Damman K, Jhund PS, Hillege HL, Van Veldhuisen DJ, Voors AA (2014) Low pulse pressure as a poor-man\u2019s indicator of a low cardiac index in patients with severe cardiac dysfunction. J Cardiovasc Med (Hagerstown) 15(4):315\u2013321","journal-title":"J Cardiovasc Med (Hagerstown)"},{"issue":"6","key":"2070_CR11","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/j.amjcard.2003.12.011","volume":"93","author":"D Aronson","year":"2004","unstructured":"Aronson D, Burger AJ (2004) Relation between pulse pressure and survival in patients with decompensated heart failure. Am J Cardiol 93(6):785\u2013788","journal-title":"Am J Cardiol"},{"issue":"7","key":"2070_CR12","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1093\/ajh\/hpt043","volume":"26","author":"NK Sweitzer","year":"2013","unstructured":"Sweitzer NK, Hetzel SJ, Skalski J, Velez M, Eggleston K, Mitchell GF (2013) Left ventricular responses to acute changes in late systolic pressure augmentation in older adults. Am J Hypertens 26(7):866\u2013871","journal-title":"Am J Hypertens"},{"issue":"1","key":"2070_CR13","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1378\/chest.99.1.112","volume":"99","author":"R Cooper","year":"1991","unstructured":"Cooper R, Ghali J, Simmons BE, Castaner A (1991) Elevated pulmonary artery pressure an independent predictor of mortality. Chest 99(1):112\u2013120","journal-title":"Chest"},{"issue":"3","key":"2070_CR14","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.cardfail.2015.11.012","volume":"22","author":"LB Cooper","year":"2016","unstructured":"Cooper LB, Mentz RJ, Stevens SR, Felker GM, Lombardi C, Metra M, Stevenson LW, O\u2019Connor CM, Milano CA, Patel CB, Rogers JG (2016) Hemodynamic predictors of heart failure morbidity and mortality: fluid or flow? J Card Fail 22(3):182\u2013189","journal-title":"J Card Fail"},{"issue":"13","key":"2070_CR15","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1001\/jama.294.13.1625","volume":"294","author":"C Binanay","year":"2005","unstructured":"Binanay C, Califf RM, Hasselblad V, O\u2019Connor CM, Shah MR, Sopko G, Stevenson LW, Francis GS, Leier CV, Miller LW, ESCAPE Investigators and ESCAPE Study Coordinators (2005) Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial. JAMA 294(13):1625\u20131633","journal-title":"JAMA"},{"issue":"5","key":"2070_CR16","doi-asserted-by":"publisher","first-page":"M724","DOI":"10.1097\/00002480-199609000-00083","volume":"42","author":"Y Orime","year":"1996","unstructured":"Orime Y, Shiono M, Nakata K, Hata M, Sezai A, Yamada H, Iida M, Kashiwazaki S, Nemoto M, Kinoshita J, Kojima T, Saito T, Sezai Y (1996) The role of pulsatility in end-organ microcirculation after cardiogenic shock. ASAIO J 42(5):M724\u2013M729","journal-title":"ASAIO J"},{"issue":"2","key":"2070_CR17","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1177\/0267659107080115","volume":"22","author":"B Ji","year":"2007","unstructured":"Ji B, Undar A (2007) Comparison of perfusion modes on microcirculation during acute and chronic cardiac support: is there a difference? Perfusion 22(2):115\u2013119","journal-title":"Perfusion"},{"issue":"4","key":"2070_CR18","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1016\/S0003-4975(02)03846-8","volume":"74","author":"S Saito","year":"2002","unstructured":"Saito S, Westaby S, Piggot D, Dudnikov S, Robson D, Catarino PA, Clelland C, Nojiri C (2002) End-organ function during chronic nonpulsatile circulation. Ann Thorac Surg 74(4):1080\u20131085","journal-title":"Ann Thorac Surg"},{"issue":"13","key":"2070_CR19","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1056\/NEJM198409273111303","volume":"311","author":"JN Cohn","year":"1984","unstructured":"Cohn JN, Levine TB, Olivari MT, Garberg V, Lura D, Francis GS, Simon AB, Rector T (1984) Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med 311(13):819\u2013823","journal-title":"N Engl J Med"},{"issue":"8","key":"2070_CR20","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/j.cardfail.2017.04.014","volume":"23","author":"CW Yancy","year":"2017","unstructured":"Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Colvin MM, Drazner MH, Filippatos GS, Fonarow GC, Givertz MM, Hollenberg SM, Lindenfeld J, Masoudi FA, McBride PE, Peterson PN, Stevenson LW, Westlake C (2017) 2017 ACC\/AHA\/HFSA focused update of the 2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Task Force on clinical practice guidelines and the Heart Failure Society of America. J Card Fail 23(8):628\u2013651","journal-title":"J Card Fail"},{"issue":"1","key":"2070_CR21","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1161\/01.CIR.96.1.308","volume":"96","author":"SS Franklin","year":"1997","unstructured":"Franklin SS, Gustin WT, Wong ND, Larson MG, Weber MA, Kannel WB, Levy D (1997) Hemodynamic patterns of age-related changes in blood pressure the Framingham Heart Study. Circulation 96(1):308\u2013315","journal-title":"Circulation"},{"issue":"7","key":"2070_CR22","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1001\/jama.281.7.634","volume":"281","author":"CU Chae","year":"1999","unstructured":"Chae CU, Pfeffer MA, Glynn RJ, Mitchell GF, Taylor JO, Hennekens CH (1999) Increased pulse pressure and risk of heart failure in the elderly. JAMA 281(7):634\u2013639","journal-title":"JAMA"},{"issue":"1","key":"2070_CR23","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.jchf.2015.09.012","volume":"4","author":"WK Laskey","year":"2016","unstructured":"Laskey WK, Wu J, Schulte PJ, Hernandez AF, Yancy CW, Heidenreich PA, Bhatt DL, Fonarow GC (2016) Association of arterial pulse pressure with long-term clinical outcomes in patients with heart failure. JACC Heart Fail 4(1):42\u201349","journal-title":"JACC Heart Fail"},{"issue":"3","key":"2070_CR24","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1161\/01.HYP.32.3.556","volume":"32","author":"N Stergiopulos","year":"1998","unstructured":"Stergiopulos N, Westerhof N (1998) Determinants of pulse pressure. Hypertension 32(3):556\u2013559","journal-title":"Hypertension"},{"issue":"6","key":"2070_CR25","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1161\/01.CIR.80.6.1652","volume":"80","author":"R Kelly","year":"1989","unstructured":"Kelly R, Hayward C, Avolio A, O\u2019Rourke M (1989) Noninvasive determination of age-related changes in the human arterial pulse. Circulation 80(6):1652\u20131659","journal-title":"Circulation"},{"issue":"4","key":"2070_CR26","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1002\/ejhf.1436","volume":"21","author":"I Ikonomidis","year":"2019","unstructured":"Ikonomidis I, Aboyans V, Blacher J, Brodmann M, Brutsaert DL, Chirinos JA, De Carlo M, Delgado V, Lancellotti P, Lekakis J, Mohty D, Nihoyannopoulos P, Parissis J, Rizzoni D, Ruschitzka F, Seferovic P, Stabile E, Tousoulis D, Vinereanu D, Vlachopoulos C, Vlastos D, Xaplanteris P, Zimlichman R, Metra M (2019) The role of ventricular-arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association. Eur J Heart Fail 21(4):402\u2013424","journal-title":"Eur J Heart Fail"},{"issue":"10","key":"2070_CR27","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1016\/S0735-1097(03)00309-7","volume":"41","author":"A Nohria","year":"2003","unstructured":"Nohria A, Tsang SW, Fang JC, Lewis EF, Jarcho JA, Mudge GH, Stevenson LW (2003) Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure. J Am Coll Cardiol 41(10):1797\u20131804","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"2070_CR28","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1067\/mhj.2000.110933","volume":"140","author":"C Lucas","year":"2000","unstructured":"Lucas C, Johnson W, Hamilton MA, Fonarow GC, Woo MA, Flavell CM, Creaser JA, Stevenson LW (2000) Freedom from congestion predicts good survival despite previous class IV symptoms of heart failure. Am Heart J 140(6):840\u2013847","journal-title":"Am Heart J"},{"issue":"1 Suppl","key":"2070_CR29","doi-asserted-by":"publisher","first-page":"S40","DOI":"10.1097\/01.CCM.0000296280.71595.64","volume":"36","author":"G Cotter","year":"2008","unstructured":"Cotter G, Cotter OM, Kaluski E (2008) Hemodynamic monitoring in acute heart failure. Crit Care Med 36(1 Suppl):S40-43","journal-title":"Crit Care Med"},{"key":"2070_CR30","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.ijcard.2018.07.069","volume":"269","author":"R Doshi","year":"2018","unstructured":"Doshi R, Patel H, Shah P (2018) Pulmonary artery catheterization use and mortality in hospitalizations with HFrEF and HFpEF: a nationally representative trend analysis from 2005 to 2014. Int J Cardiol 269:289\u2013291","journal-title":"Int J Cardiol"},{"issue":"12","key":"2070_CR31","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/j.cardfail.2016.03.019","volume":"22","author":"S Mazimba","year":"2016","unstructured":"Mazimba S, Kennedy JLW, Zhuo D, Bergin J, Abuannadi M, Tallaj J, Bilchick KC (2016) Decreased pulmonary arterial proportional pulse pressure after pulmonary artery catheter optimization for advanced heart failure is associated with adverse clinical outcomes. J Card Fail 22(12):954\u2013961","journal-title":"J Card Fail"},{"issue":"11","key":"2070_CR32","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1002\/clc.22752","volume":"40","author":"H Mwansa","year":"2017","unstructured":"Mwansa H, Bilchick KC, Parker AM, Harding W, Ruth B, Kennedy JLW, Mysore M, Kwon Y, Mihalek A, Mazimba S (2017) Decreased pulmonary arterial proportional pulse pressure is associated with increased mortality in group 1 pulmonary hypertension. Clin Cardiol 40(11):988\u2013992","journal-title":"Clin Cardiol"},{"issue":"13","key":"2070_CR33","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1016\/j.jacc.2018.12.084","volume":"73","author":"BN Tehrani","year":"2019","unstructured":"Tehrani BN, Truesdell AG, Sherwood MW, Desai S, Tran HA, Epps KC, Singh R, Psotka M, Shah P, Cooper LB, Rosner C, Raja A, Barnett SD, Saulino P, deFilippi CR, Gurbel PA, Murphy CE, O\u2019Connor CM (2019) Standardized team-based care for cardiogenic shock. J Am Coll Cardiol 73(13):1659\u20131669","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"2070_CR34","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.jacc.2004.03.060","volume":"44","author":"R Fincke","year":"2004","unstructured":"Fincke R, Hochman JS, Lowe AM, Menon V, Slater JN, Webb JG, LeJemtel TH, Cotter G, SHOCK Investigators (2004) Cardiac power is the strongest hemodynamic correlate of mortality in cardiogenic shock: a report from the SHOCK trial registry. J Am Coll Cardiol 44(2):340\u2013348","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"2070_CR35","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.cardfail.2020.01.014","volume":"26","author":"S Cesini","year":"2020","unstructured":"Cesini S, Bhagra S, Pettit SJ (2020) Low pulmonary artery pulsatility index is associated with adverse outcomes in ambulatory patients with advanced heart failure. J Card Fail 26(4):352\u2013359","journal-title":"J Card Fail"},{"issue":"1","key":"2070_CR36","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.healun.2015.06.009","volume":"35","author":"G Kang","year":"2016","unstructured":"Kang G, Ha R, Banerjee D (2016) Pulmonary artery pulsatility index predicts right ventricular failure after left ventricular assist device implantation. J Heart Lung Transplant 35(1):67\u201373","journal-title":"J Heart Lung Transplant"},{"issue":"9","key":"2070_CR37","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1056\/NEJM197008272830902","volume":"283","author":"HJ Swan","year":"1970","unstructured":"Swan HJ, Ganz W, Forrester J, Marcus H, Diamond G, Chonette D (1970) Catheterization of the heart in man with use of a flow-directed balloon-tipped catheter. N Engl J Med 283(9):447\u2013451","journal-title":"N Engl J Med"},{"issue":"21","key":"2070_CR38","doi-asserted-by":"publisher","first-page":"1995","DOI":"10.1056\/NEJMoa1911303","volume":"381","author":"JJV McMurray","year":"2019","unstructured":"McMurray JJV, Solomon SD, Inzucchi SE, K\u00f8ber L, Kosiborod MN, Martinez FA, Ponikowski P, Sabatine MS, Anand IS, B\u011blohl\u00e1vek J, B\u00f6hm M, Chiang CE, Chopra VK, de Boer RA, Desai AS, Diez M, Drozdz J, Duk\u00e1t A, Ge J, Howlett JG, Katova T, Kitakaze M, Ljungman CEA, Merkely B, Nicolau JC, O\u2019Meara E, Petrie MC, Vinh PN, Schou M, Tereshchenko S, Verma S, Held C, DeMets DL, Docherty KF, Jhund PS, Bengtsson O, Sj\u00f6strand M, Langkilde AM, DAPA-HF Trial Committees and Investigators (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction. N Engl J Med 381(21):1995\u20132008","journal-title":"N Engl J Med"},{"issue":"15","key":"2070_CR39","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1056\/NEJMoa2022190","volume":"383","author":"M Packer","year":"2020","unstructured":"Packer M, Anker SD, Butler J, Filippatos G, Pocock SJ, Carson P, Januzzi J, Verma S, Tsutsui H, Brueckmann M, Jamal W, Kimura K, Schnee J, Zeller C, Cotton D, Bocchi E, B\u00f6hm M, Choi DJ, Chopra V, Chuquiure E, Giannetti N, Janssens S, Zhang J, Gonzalez Juanatey JR, Kaul S, Brunner-La Rocca HP, Merkely B, Nicholls SJ, Perrone S, Pina I, Ponikowski P, Sattar N, Senni M, Seronde MF, Spinar J, Squire I, Taddei S, Wanner C, Zannad F, EMPEROR-Reduced Trial Investigators (2020) Cardiovascular and renal outcomes with empagliflozin in heart failure. N Engl J Med 383(15):1413\u20131424","journal-title":"N Engl J Med"},{"issue":"12","key":"2070_CR40","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1161\/CIRCULATIONAHA.117.029529","volume":"136","author":"K Striepe","year":"2017","unstructured":"Striepe K, Jumar A, Ott C, Karg MV, Schneider MP, Kannenkeril D, Schmieder RE (2017) Effects of the selective sodium-glucose cotransporter 2 inhibitor empagliflozin on vascular function and central hemodynamics in patients with type 2 diabetes mellitus. Circulation 136(12):1167\u20131169","journal-title":"Circulation"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-022-02070-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00380-022-02070-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-022-02070-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T03:30:09Z","timestamp":1661311809000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00380-022-02070-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,10]]},"references-count":40,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["2070"],"URL":"https:\/\/doi.org\/10.1007\/s00380-022-02070-7","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"value":"0910-8327","type":"print"},{"value":"1615-2573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,10]]},"assertion":[{"value":"26 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}