{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T12:43:54Z","timestamp":1755693834489,"version":"3.37.3"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T00:00:00Z","timestamp":1679097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T00:00:00Z","timestamp":1679097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Japan Heart Club"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s00380-023-02258-5","type":"journal-article","created":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T03:02:46Z","timestamp":1679108566000},"page":"1075-1082","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Age- and sex-stratified normal values for circulatory and ventilatory power during ramp exercise derived from a healthy Japanese population"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8633-3487","authenticated-orcid":false,"given":"Kohei","family":"Ashikaga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruki","family":"Itoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri","family":"Ichikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiori","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Koike","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Makita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuto","family":"Omiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Nagayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro J.","family":"Akashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Committee on Exercise Prescription for Patients (CEPP) Members","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,18]]},"reference":[{"key":"2258_CR1","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1016\/j.jacc.2015.11.050","volume":"67","author":"SJ Keteyian","year":"2016","unstructured":"Keteyian SJ, Patel M, Kraus WE, Brawner CA, McConnell TR, Pi\u00f1a IL, Leifer ES, Fleg JL, Blackburn G, Fonarow GC, Chase PJ, Piner L, Vest M, O\u2019Connor CM, Ehrman JK, Walsh MN, Ewald G, Bensimhon D, Russell SD, Investigators HF-ACTION (2016) Variables measured during cardiopulmonary exercise testing as predictors of mortality in chronic systolic heart failure. J Am Coll Cardiol 67:780\u2013789","journal-title":"J Am Coll Cardiol"},{"key":"2258_CR2","doi-asserted-by":"publisher","first-page":"1883","DOI":"10.1016\/j.jacc.2005.07.051","volume":"46","author":"M Guazzi","year":"2005","unstructured":"Guazzi M, Myers J, Arena R (2005) Cardiopulmonary exercise testing in the clinical and prognostic assessment of diastolic heart failure. J Am Coll Cardiol 46:1883\u20131890","journal-title":"J Am Coll Cardiol"},{"key":"2258_CR3","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.ahj.2003.07.014","volume":"147","author":"R Arena","year":"2004","unstructured":"Arena R, Myers J, Aslam SS, Varughese EB, Peberdy MA (2004) Peak VO2 and VE\/VCO2 slope in patients with heart failure: a prognostic comparison. Am Heart J 147:354\u2013360","journal-title":"Am Heart J"},{"key":"2258_CR4","doi-asserted-by":"crossref","unstructured":"Paolillo S, Veglia F, Salvioni E, Corr\u00e0 U, Piepoli M, Lagioia R, Limongelli G, Sinagra G, Cattadori G, Scardovi AB, Metra M, Senni M, Bonomi A, Scrutinio D, Raimondo R, Emdin M, Magr\u00ec D, Parati G, Re F, Cicoira M, Min\u00e0 C, Correale M, Frigerio M, Bussotti M, Battaia E, Guazzi M, Badagliacca R, Di Lenarda A, Maggioni A, Passino C, Sciomer S, Pacileo G, Mapelli M, Vignati C, Clemenza F, Binno S, Lombardi C, Filardi PP, Agostoni P, MECKI Score Research Group (2019) Heart failure prognosis over time: how the prognostic role of oxygen consumption and ventilatory efficiency during exercise has changed in the last 20 years. Eur J Heart Fail 21:208\u2013217","DOI":"10.1002\/ejhf.1364"},{"key":"2258_CR5","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1016\/S0735-1097(97)00078-8","volume":"29","author":"TP Chua","year":"1997","unstructured":"Chua TP, Ponikowski P, Harrington D, Anker SD, Webb-Peploe K, Clark AL, Poole-Wilson PA, Coats AJS (1997) Clinical correlates and prognostic significance of the ventilatory response to exercise in chronic heart failure. J Am Coll Cardiol 29:1585\u20131590","journal-title":"J Am Coll Cardiol"},{"key":"2258_CR6","doi-asserted-by":"publisher","first-page":"2803","DOI":"10.1161\/01.CIR.101.24.2803","volume":"101","author":"FX Kleber","year":"2000","unstructured":"Kleber FX, Vietzke G, Wernecke KD, Bauer U, Opitz C, Wensel R, Sperfeld A, Gl\u00e4ser S (2000) Impairment of ventilatory efficiency in heart failure: prognostic impact. Circulation 101:2803\u20132809","journal-title":"Circulation"},{"key":"2258_CR7","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1161\/CIRCHEARTFAILURE.112.968529","volume":"5","author":"DE Forman","year":"2012","unstructured":"Forman DE, Guazzi M, Myers J, Chase P, Bensimhon D, Cahalin LP, Peberdy MA, Ashley E, West E, Daniels KM, Arena R (2012) Ventilatory power: a novel index that enhances prognostic assessment of patients with heart failure. Circ Heart Fail 5:621\u2013626","journal-title":"Circ Heart Fail"},{"key":"2258_CR8","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1053\/euhj.2001.2966","volume":"23","author":"A Cohen-Solal","year":"2002","unstructured":"Cohen-Solal A, Tabet JY, Logeart D, Bourgoin P, Tokmakova M, Dahan M (2002) A non-invasively determined surrogate of cardiac power (\u2018circulatory power\u2019) at peak exercise is a powerful prognostic factor in chronic heart failure. Eur Heart J 23:806\u2013814","journal-title":"Eur Heart J"},{"key":"2258_CR9","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.acvd.2010.01.003","volume":"103","author":"J Jaussaud","year":"2010","unstructured":"Jaussaud J, Blanc P, Derval N, Bordachar P, Courregelongue M, Roudaut R, Douard H (2010) Ventilatory response and peak circulatory power: new functional markers of response after cardiac resynchronization therapy. Arch Cardiovasc Dis 103:184\u2013191","journal-title":"Arch Cardiovasc Dis"},{"key":"2258_CR10","first-page":"476","volume":"104","author":"V Castello-Sim\u00f5es","year":"2015","unstructured":"Castello-Sim\u00f5es V, Minatel V, Karsten M, Sim\u00f5es RP, Perseguini NM, Milan JC, Arena R, Neves LM, Borghi-Silva A, Catai AM (2015) Circulatory and ventilatory power: characterization in patients with coronary artery disease. Arq Bras Cardiol 104:476\u2013485","journal-title":"Arq Bras Cardiol"},{"key":"2258_CR11","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1249\/MSS.0000000000002985","volume":"54","author":"V Busque","year":"2022","unstructured":"Busque V, Myers J, Arena R, Kaminsky LA, Peterman JE (2022) Peak circulatory power during maximal cardiopulmonary exercise testing: reference standards from the FRIEND registry. Med Sci Sports Exerc 54:1919\u20131924","journal-title":"Med Sci Sports Exerc"},{"key":"2258_CR12","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.jjcc.2012.09.010","volume":"61","author":"H Itoh","year":"2013","unstructured":"Itoh H, Ajisaka R, Koike A, Makita S, Omiya K, Kato Y, Adachi H, Nagayama M, Maeda T, Tajima A, Harada N, Taniguchi K, Committee on Exercise Prescription for Patients (CEPP) Members (2013) Heart rate and blood pressure response to ramp exercise and exercise capacity in relation to age, gender, and mode of exercise in a healthy population. J Cardiol 61:71\u201378","journal-title":"J Cardiol"},{"key":"2258_CR13","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.jjcc.2020.07.008","volume":"77","author":"K Ashikaga","year":"2021","unstructured":"Ashikaga K, Itoh H, Maeda T, Itoh H, Ichikawa Y, Tanaka S, Ajisaka R, Koike A, Makita S, Omiya K, Kato Y, Adachi H, Nagayama M, Tajima A, Harada N, Akashi YJ, Committee on Exercise Prescription for Patients (CEPP) Members (2021) Ventilatory efficiency during ramp exercise in relation to age and sex in a healthy Japanese population. J Cardiol 77:57\u201364","journal-title":"J Cardiol"},{"key":"2258_CR14","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1152\/jappl.1986.60.6.2020","volume":"60","author":"WL Beaver","year":"1986","unstructured":"Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60:2020\u20132027","journal-title":"J Appl Physiol"},{"key":"2258_CR15","first-page":"219","volume":"112","author":"K Wasserman","year":"1975","unstructured":"Wasserman K, Whipp BJ (1975) Exercise physiology in health and disease. Am Rev Respir Dis 112:219\u2013249","journal-title":"Am Rev Respir Dis"},{"key":"2258_CR16","doi-asserted-by":"publisher","first-page":"S35","DOI":"10.1164\/arrd.1984.129.2P2.S35","volume":"129","author":"K Wasserman","year":"1984","unstructured":"Wasserman K (1984) The anaerobic threshold measurement to evaluate exercise performance. Am Rev Respir Dis 129:S35\u2013S40","journal-title":"Am Rev Respir Dis"},{"key":"2258_CR17","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1093\/oxfordjournals.eurheartj.a060747","volume":"16","author":"G Roul","year":"1995","unstructured":"Roul G, Moulichon ME, Bareiss P, Gries P, Koegler A, Sacrez J, Germain PH, Mossard JM, Sacrez A (1995) Prognostic factors of chronic heart failure in NYHA class II or III: value of invasive exercise haemodynamic data. Eur Heart J 16:1387\u20131398","journal-title":"Eur Heart J"},{"key":"2258_CR18","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1177\/2047487319863506","volume":"27","author":"P Laforgia","year":"2020","unstructured":"Laforgia P, Bandera F, Alfonzetti E, Guazzi M (2020) Exercise chronotropic incompetence phenotypes the level of cardiovascular risk and exercise gas exchange impairment in the general population. An analysis of the Euro-EX prevention trial. Eur J Prev Cardiol 27:526\u2013535","journal-title":"Eur J Prev Cardiol"},{"key":"2258_CR19","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1164\/rccm.2202033","volume":"166","author":"XG Sun","year":"2002","unstructured":"Sun XG, Hansen JE, Garatachea N, Storer TW, Wasserman K (2002) Ventilatory efficiency during exercise in healthy subjects. Am J Respir Crit Care Med 166:1443\u20131448","journal-title":"Am J Respir Crit Care Med"},{"key":"2258_CR20","doi-asserted-by":"publisher","first-page":"e1830","DOI":"10.1002\/pri.1830","volume":"25","author":"AD Santos-de-Ara\u00fajo","year":"2020","unstructured":"Santos-de-Ara\u00fajo AD, Bassi-Dibai D, Veiga TP, Caruso FCR, Mendes RG, J\u00fanior JCB, Arena R, Schwartzmann PV, Sim\u00f5es RP, Borghi-Silva A (2020) Circulatory and ventilatory power in diabetic patients: secondary analysis of a randomized controlled trial. Physiother Res Int 25:e1830","journal-title":"Physiother Res Int"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-023-02258-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00380-023-02258-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-023-02258-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T22:34:02Z","timestamp":1687559642000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00380-023-02258-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,18]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["2258"],"URL":"https:\/\/doi.org\/10.1007\/s00380-023-02258-5","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"type":"print","value":"0910-8327"},{"type":"electronic","value":"1615-2573"}],"subject":[],"published":{"date-parts":[[2023,3,18]]},"assertion":[{"value":"7 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}