{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T07:45:46Z","timestamp":1785311146362,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:00:00Z","timestamp":1696377600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:00:00Z","timestamp":1696377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1007\/s00380-023-02319-9","type":"journal-article","created":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T06:01:53Z","timestamp":1696399313000},"page":"160-166","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Visceral adiposity in patients with lipomatous hypertrophy of the interatrial septum"],"prefix":"10.1007","volume":"39","author":[{"given":"Carlo A.","family":"Mallio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Di Gennaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pescosolido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7377-6067","authenticated-orcid":false,"given":"Caterina","family":"Bernetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Lucia","family":"Piccolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitaliano","family":"Buffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo C.","family":"Quattrocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Beomonte Zobel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,4]]},"reference":[{"key":"2319_CR1","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.echo.2010.04.015","volume":"23","author":"JJ Silbiger","year":"2010","unstructured":"Silbiger JJ, Bazaz R, Trost B (2010) Lipomatous hypertrophy of the interatrial septum revisited. J Am Soc Echocardiogr 23:789\u2013790","journal-title":"J Am Soc Echocardiogr"},{"key":"2319_CR2","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/0735-1097(93)90839-S","volume":"22","author":"J Shirani","year":"1993","unstructured":"Shirani J, Roberts WC (1993) Clinical, electrocardiographic and morphologic features of massive fatty deposits (\u201clipomatous hypertrophy\u201d) in the atrial septum. J Am Coll Cardiol 22:226\u2013238","journal-title":"J Am Coll Cardiol"},{"key":"2319_CR3","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1378\/chest.124.6.2068","volume":"124","author":"CM Heyer","year":"2003","unstructured":"Heyer CM, Kagel T, Lemburg SP, Bauer TT, Nicolas V (2003) Lipomatous hypertrophy of the interatrial septum. Chest 124:2068\u20132073","journal-title":"Chest"},{"key":"2319_CR4","doi-asserted-by":"publisher","first-page":"bcr2012006611","DOI":"10.1136\/bcr-2012-006611","volume":"2012","author":"KM Lampropoulos","year":"2012","unstructured":"Lampropoulos KM, Kotsas D, Iliopoulos T (2012) Lipomatous hypertrophy of interatrial septum. BMJ Case Rep 2012:bcr2012006611","journal-title":"BMJ Case Rep"},{"key":"2319_CR5","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/0002-9149(92)90629-D","volume":"70","author":"WT Pochis","year":"1992","unstructured":"Pochis WT, Saeian K, Sagar KB (1992) Usefulness of transesophageal echocardiography in diagnosing lipomatous hypertrophy of the atrial septum with comparison to transthoracic echocardiography. Am J Cardiol 70:396\u2013398","journal-title":"Am J Cardiol"},{"key":"2319_CR6","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.ijcard.2006.11.150","volume":"121","author":"T Xanthos","year":"2007","unstructured":"Xanthos T, Giannakopoulos N, Papadimitriou L (2007) Lipomatous hypertrophy of the interatrial septum: a pathological and clinical approach. Int J Cardiol 121:4\u20138","journal-title":"Int J Cardiol"},{"key":"2319_CR7","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.2214\/ajr.168.4.9124119","volume":"168","author":"JF Meaney","year":"1997","unstructured":"Meaney JF, Kazerooni EA, Jamadar DA, Korobkin M (1997) CT appearance of lipomatous hypertrophy of the interatrial septum. Am J Roentgenol 168:1081\u20131084","journal-title":"Am J Roentgenol"},{"key":"2319_CR8","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/jcu.1870070503","volume":"7","author":"GC Rosenquist","year":"1979","unstructured":"Rosenquist GC, Sweeney LJ, Ruckman RN, McAllister HA (1979) Atrial septal thickness and area in normal heart specimens and in those with ostium secundum atrial septal defects. J Clin Ultrasound 7:345\u2013348","journal-title":"J Clin Ultrasound"},{"key":"2319_CR9","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s004150050274","volume":"245","author":"MT Dotti","year":"1998","unstructured":"Dotti MT, Mondillo S, Plewnia K, Agricola E, Federico A (1998) Cerebrotendinous xanthomatosis: evidence of lipomatous hypertrophy of the atrial septum. J Neurol 245:723\u2013726","journal-title":"J Neurol"},{"key":"2319_CR10","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1038\/sj.ijo.0801867","volume":"26","author":"G Enzi","year":"2002","unstructured":"Enzi G, Busetto L, Ceschin E, Coin A, Digito M, Pigozzo S (2002) Multiple symmetric lipomatosis: clinical aspects and outcome in a long-term longitudinal study. Int J Obes Relat Metab Disord 26:253\u2013261","journal-title":"Int J Obes Relat Metab Disord"},{"key":"2319_CR11","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1007\/s11547-020-01310-y","volume":"126","author":"F Greco","year":"2021","unstructured":"Greco F, Mallio CA (2021) Relationship between visceral adipose tissue and genetic mutations (VHL and KDM5C) in clear cell renal cell carcinoma. Radiol Med 126:645\u2013651","journal-title":"Radiol Med"},{"key":"2319_CR12","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s12306-015-0355-2","volume":"99","author":"CC Quattrocchi","year":"2015","unstructured":"Quattrocchi CC, Giona A, Di Martino A, Gaudino F, Mallio CA, Errante Y, Occhicone F, Vitali MA, Zobel BB, Denaro V (2015) Lumbar subcutaneous edema and degenerative spinal disease in patients with low back pain: a retrospective MRI study. Musculoskelet Surg 99:159\u2013163","journal-title":"Musculoskelet Surg"},{"key":"2319_CR13","doi-asserted-by":"publisher","first-page":"132","DOI":"10.4103\/ccij.ccij_62_18","volume":"7","author":"F Greco","year":"2018","unstructured":"Greco F, Cirimele V, Mallio C, Zobel B, Grasso R (2018) Increased visceral adipose tissue in male patients with clear cell renal cell carcinoma. Clin Cancer Investig J 7:132","journal-title":"Clin Cancer Investig J"},{"key":"2319_CR14","doi-asserted-by":"publisher","first-page":"463","DOI":"10.3892\/ol.2016.5408","volume":"13","author":"HP Zhang","year":"2017","unstructured":"Zhang HP, Zou J, Xu ZQ, Ruan J, Yang SD, Yin Y, Mu HJ (2017) Association of leptin, visfatin, apelin, resistin and adiponectin with clear cell renal cell carcinoma. Oncol Lett 13:463\u2013468","journal-title":"Oncol Lett"},{"key":"2319_CR15","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1038\/nature05488","volume":"444","author":"J-P Despr\u00e9s","year":"2006","unstructured":"Despr\u00e9s J-P, Lemieux I (2006) Abdominal obesity and metabolic syndrome. Nature 444:881\u2013887","journal-title":"Nature"},{"key":"2319_CR16","doi-asserted-by":"publisher","first-page":"2448","DOI":"10.2337\/db15-1671","volume":"65","author":"H Yaghootkar","year":"2016","unstructured":"Yaghootkar H, Lotta LA, Tyrrell J, Smit RA, Jones SE, Donnelly L, Beaumont R, Campbell A, Tuke MA, Hayward C, Ruth KS, Padmanabhan S, Jukema JW, Palmer CC, Hattersley A, Freathy RM, Langenberg C, Wareham NJ, Wood AR, Murray A, Weedon MN, Sattar N, Pearson E, Scott RA, Frayling TM (2016) Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension, and heart disease. Diabetes 65:2448\u20132460","journal-title":"Diabetes"},{"key":"2319_CR17","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1111\/joim.12540","volume":"280","author":"U Smith","year":"2016","unstructured":"Smith U, Kahn BB (2016) Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids. J Intern Med 280:465\u2013475","journal-title":"J Intern Med"},{"key":"2319_CR18","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1161\/CIRCULATIONAHA.117.029617","volume":"137","author":"IJ Neeland","year":"2018","unstructured":"Neeland IJ, Poirier P, Despr\u00e9s J-P (2018) Cardiovascular and metabolic heterogeneity of obesity. Circulation 137:1391\u20131406","journal-title":"Circulation"},{"key":"2319_CR19","doi-asserted-by":"publisher","first-page":"20","DOI":"10.21037\/shc.2018.03.03","volume":"2","author":"CA Mallio","year":"2018","unstructured":"Mallio CA, Greco F, Pacella G, Schena E, Beomonte Zobel B (2018) Gender-based differences of abdominal adipose tissue distribution in non-small cell lung cancer patients. Shanghai Chest 2:20\u201320","journal-title":"Shanghai Chest"},{"key":"2319_CR20","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1097\/00000478-199606000-00004","volume":"20","author":"AP Burke","year":"1996","unstructured":"Burke AP, Litovsky S, Virmani R (1996) Lipomatous hypertrophy of the atrial septum presenting as a right atrial mass. Am J Surg Pathol 20:678\u2013685. https:\/\/doi.org\/10.1097\/00000478-199606000-00004","journal-title":"Am J Surg Pathol"},{"key":"2319_CR21","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1111\/j.1467-789X.2009.00623.x","volume":"11","author":"MM Ibrahim","year":"2010","unstructured":"Ibrahim MM (2010) Subcutaneous and visceral adipose tissue: structural and functional differences. Obes Rev 11:11\u201318. https:\/\/doi.org\/10.1111\/j.1467-789X.2009.00623.x","journal-title":"Obes Rev"},{"key":"2319_CR22","doi-asserted-by":"publisher","first-page":"4461","DOI":"10.21037\/qims-21-370","volume":"11","author":"F Greco","year":"2021","unstructured":"Greco F, Mallio CA (2021) Artificial intelligence and abdominal adipose tissue analysis: a literature review. Quant Imaging Med Surg 11:4461\u20134474","journal-title":"Quant Imaging Med Surg"},{"key":"2319_CR23","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1038\/nrc1408","volume":"4","author":"EE Calle","year":"2004","unstructured":"Calle EE, Kaaks R (2004) Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 4:579\u2013591. https:\/\/doi.org\/10.1038\/nrc1408","journal-title":"Nat Rev Cancer"},{"key":"2319_CR24","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/S2213-8587(19)30084-1","volume":"7","author":"IJ Neeland","year":"2019","unstructured":"Neeland IJ, Ross R, Despr\u00e9s JP, Matsuzawa Y, Yamashita S, Shai I, Seidell J, Magni P, Santos RD, Arsenault B, Cuevas A, Hu FB, Griffin B, Zambon A, Barter P, Fruchart JC, Eckel RH (2019) Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement. Lancet Diabetes Endocrinol 7:715\u2013725. https:\/\/doi.org\/10.1016\/S2213-8587(19)30084-1","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2319_CR25","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.21037\/qims-21-945","volume":"12","author":"F Greco","year":"2022","unstructured":"Greco F, Salgado R, Van Hecke W, Del Buono R, Parizel PM, Mallio CA (2022) Epicardial and pericardial fat analysis on CT images and artificial intelligence: a literature review. Quant Imaging Med Surg 12:2075\u20132089","journal-title":"Quant Imaging Med Surg"},{"key":"2319_CR26","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.1161\/ATVBAHA.111.228262","volume":"31","author":"CE Ndumele","year":"2011","unstructured":"Ndumele CE, Nasir K, Concei\u00e7ao RD, Carvalho JA, Blumenthal RS, Santos RD (2011) Hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased systemic inflammation. Arterioscler Thromb Vasc Biol 31:1927\u20131932. https:\/\/doi.org\/10.1161\/ATVBAHA.111.228262","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2319_CR27","doi-asserted-by":"publisher","first-page":"E439","DOI":"10.1002\/oby.20135","volume":"21","author":"IJ Neeland","year":"2013","unstructured":"Neeland IJ, Ayers CR, Rohatgi AK, Turer AT, Berry JD, Das SR, Vega GL, Khera A, McGuire DK, Grundy SM, de Lemos JA (2013) Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults. Obesity 21:E439\u2013E447. https:\/\/doi.org\/10.1002\/oby.20135","journal-title":"Obesity"},{"key":"2319_CR28","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.tem.2011.07.003","volume":"22","author":"G Iacobellis","year":"2011","unstructured":"Iacobellis G, Bianco AC (2011) Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features. Trends Endocrinol Metab 22:450\u2013457. https:\/\/doi.org\/10.1016\/j.tem.2011.07.003","journal-title":"Trends Endocrinol Metab"},{"key":"2319_CR29","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004378","author":"CX Wong","year":"2016","unstructured":"Wong CX, Sun MT, Odutayo A, Emdin CA, Mahajan R, Lau DH, Pathak RK, Wong DT, Selvanayagam JB, Sanders P, Clarke R (2016) Associations of epicardial, abdominal, and overall adiposity with atrial fibrillation. Circ Arrhythm Electrophysiol. https:\/\/doi.org\/10.1161\/CIRCEP.116.004378","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2319_CR30","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/j.jacc.2012.11.062","volume":"61","author":"AA Mahabadi","year":"2013","unstructured":"Mahabadi AA, Berg MH, Lehmann N, K\u00e4lsch H, Bauer M, Kara K, Dragano N, Moebus S, J\u00f6ckel KH, Erbel R, M\u00f6hlenkamp S (2013) Association of epicardial fat with cardiovascular risk factors and incident myocardial infarction in the general population. J Am Coll Cardiol 61:1388\u20131395. https:\/\/doi.org\/10.1016\/j.jacc.2012.11.062","journal-title":"J Am Coll Cardiol"},{"key":"2319_CR31","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.case.2017.06.005","volume":"1","author":"A Xanthopoulos","year":"2017","unstructured":"Xanthopoulos A, Giamouzis G, Alexopoulos N, Kitai T, Triposkiadis F, Skoularigis J (2017) Lipomatous hypertrophy of the interatrial septum: a case report and review of the literature. CASE 1:182\u2013189. https:\/\/doi.org\/10.1016\/j.case.2017.06.005","journal-title":"CASE"},{"key":"2319_CR32","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1152\/physrev.00033.2011","volume":"93","author":"A Tchernof","year":"2013","unstructured":"Tchernof A, Despr\u00e9s J-P (2013) Pathophysiology of human visceral obesity: an update. Physiol Rev 93:359\u2013404. https:\/\/doi.org\/10.1152\/physrev.00033.2011","journal-title":"Physiol Rev"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-023-02319-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00380-023-02319-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-023-02319-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T09:08:09Z","timestamp":1704964089000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00380-023-02319-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,4]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["2319"],"URL":"https:\/\/doi.org\/10.1007\/s00380-023-02319-9","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"value":"0910-8327","type":"print"},{"value":"1615-2573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,4]]},"assertion":[{"value":"20 May 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This is a retrospective observational study; hence no ethical approval is required. The study agreed with the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}