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Dr. Otani received grant support from Sato Pharmaceutical Co., Ltd. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by the Ethical Committee of the Dokkyo Medical University Nikko Medical Center (ethical license number Nikko 21\u2013011). This study was conducted in accordance with the \u201cDeclaration of Helsinki\u201d by the World Medical Association and the \u201cEthical Guidelines for Medical and Health Research Involving Human Subjects\u201d by the Ministry of Education, Culture, Sports, Science and Technology and the Ministry of Health, Labor and Welfare (established on December 22, 2014, and partially revised on March 27, 2023). Informed consent was obtained from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all patients for participation in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}