{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:04:40Z","timestamp":1790647480635,"version":"4.1.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Vessels"],"DOI":"10.1007\/s00380-026-02771-3","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:46:50Z","timestamp":1790646410000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical outcomes of conservative management for acute Stanford type A intramural hematoma: a multicenter retrospective study"],"prefix":"10.1007","author":[{"given":"Hiroshi","family":"Okada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Kitamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiaki","family":"Shikata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Narita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Motoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujiro","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisato","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kagami","family":"Miyaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"2771_CR1","doi-asserted-by":"crossref","unstructured":"Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, Evangelista A, Fattori R, Suzuki T, Oh JK, Moore AG, Malouf JF, Pape LA, Gaca C, Sechtem U, Lenferink S, Deutsch HJ, Diedrichs H, Marcos J, Llovet A, Gilon D, Das SK, Armstrong WF, Deeb GM, Eagle KA (2000) The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA 283:897\u2013903","DOI":"10.1001\/jama.283.7.897"},{"key":"2771_CR2","doi-asserted-by":"publisher","first-page":"1846","DOI":"10.1161\/CIRCULATIONAHA.117.031264","volume":"137","author":"A Evangelista","year":"2018","unstructured":"Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Di Eusanio M, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O\u2019Gara P, Suzuki T, Nienaber CA, Eagle KA (2018) Insights from the International Registry of Acute Aortic Dissection: a 20-year experience of collaborative clinical research. Circulation 137:1846\u20131860","journal-title":"Circulation"},{"key":"2771_CR3","doi-asserted-by":"publisher","first-page":"524","DOI":"10.21037\/acs.2019.07.08","volume":"8","author":"Z Al Rstum","year":"2019","unstructured":"Al Rstum Z, Tanaka A, Eisenberg SB, Estrera AL (2019) Optimal timing of type A intramural hematoma repair. Ann Cardiothorac Surg 8:524\u2013530","journal-title":"Ann Cardiothorac Surg"},{"key":"2771_CR4","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1093\/aje\/kwm324","volume":"167","author":"S Suissa","year":"2008","unstructured":"Suissa S (2008) Immortal time bias in pharmacoepidemiology. Am J Epidemiol 167:492\u2013499","journal-title":"Am J Epidemiol"},{"key":"2771_CR5","doi-asserted-by":"publisher","first-page":"b5087","DOI":"10.1136\/bmj.b5087","volume":"340","author":"LE L\u00e9vesque","year":"2010","unstructured":"L\u00e9vesque LE, Hanley JA, Kezouh A, Suissa S (2010) Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ 340:b5087","journal-title":"BMJ"},{"key":"2771_CR6","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1253\/circj.CJ-22-0794","volume":"87","author":"H Ogino","year":"2023","unstructured":"Ogino H, Iida O, Akutsu K, Chiba Y, Hayashi H, Ishibashi-Ueda H, Kaji S, Kato M, Komori K, Matsuda H, Minatoya K, Morisaki H, Ohki T, Saiki Y, Shigematsu K, Shiiya N, Shimizu H, Azuma N, Higami H, Ichihashi S, Iwahashi T, Kamiya K, Katsumata T, Kawaharada N, Kinoshita Y, Matsumoto T, Miyamoto S, Morisaki T, Morota T, Nanto K, Nishibe T, Okada K, Orihashi K, Tazaki J, Toma M, Tsukube T, Uchida K, Ueda T, Usui A, Yamanaka K, Yamauchi H, Yoshioka K, Kimura T, Miyata T, Okita Y, Ono M, Ueda Y, Japanese Circulation Society, Japanese Society for Cardiovascular Surgery, Japanese Association for Thoracic Surgery, Japanese Society for Vascular Surgery Joint Working Group (2023) JCS\/JSCVS\/JATS\/JSVS 2020 guideline on diagnosis and treatment of aortic aneurysm and aortic dissection. Circ J 87:1410\u20131621","journal-title":"Circ J"},{"key":"2771_CR7","doi-asserted-by":"publisher","first-page":"e334","DOI":"10.1161\/CIR.0000000000001106","volume":"146","author":"EM Isselbacher","year":"2022","unstructured":"Isselbacher EM, Preventza O, Black JH 3rd, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A Jr, Fanola CL, Girardi LN, Hicks CW, Hui DS, Jones WS, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Ross EG, Schermerhorn ML, Singleton Times S, Tseng EE, Wang GJ, Woo YJ (2022) 2022 ACC\/AHA guideline for the diagnosis and management of aortic disease. Circulation 146:e334\u2013e482","journal-title":"Circulation"},{"issue":"Suppl 11","key":"2771_CR8","first-page":"S292","volume":"120","author":"T Kitai","year":"2009","unstructured":"Kitai T, Kaji S, Yamamuro A, Tani T, Kinoshita M, Ehara N, Kobori A, Kim K, Kita T, Furukawa Y (2009) Clinical outcomes of medical therapy and timely operation in initially diagnosed type A aortic intramural hematoma: a 20-year experience. Circulation 120(Suppl 11):S292\u2013S298","journal-title":"Circulation"},{"key":"2771_CR9","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1161\/01.cir.0000087651.30078.38","volume":"108","author":"JM Song","year":"2003","unstructured":"Song JM, Kim HS, Kang DH, Song JK, Rim SJ, Lee CW, Hong MK, Kim JJ, Park SW, Park SJ (2003) Usefulness of the initial noninvasive imaging study to predict adverse outcomes in the medical treatment of acute type A aortic intramural hematoma. Circulation 108:324\u2013328","journal-title":"Circulation"},{"key":"2771_CR10","doi-asserted-by":"publisher","first-page":"3538","DOI":"10.1093\/eurheartj\/ehae179","volume":"45","author":"L Mazzolai","year":"2024","unstructured":"Mazzolai L, Teixido-Tura G, Lanzi S, Boc V, Bossone E, Brodmann M, Bura-Rivi\u00e8re A, De Backer J, Deglise S, Della Corte A, Heiss C, Ka\u0142u\u017cna-Oleksy M, Kurpas D, McEniery CM, Mirault T, Pasquet AA, Pitcher A, Schaubroeck HAI, Schlager O, Sirnes PA, Sprynger MG, Stabile E, Steinbach F, Thielmann M, van Kimmenade RRJ, Venermo M, Rodriguez-Palomares JF, ESC Scientific Document Group (2024) 2024 ESC guidelines for the management of peripheral arterial and aortic diseases. Eur Heart J 45:3538\u20133700","journal-title":"Eur Heart J"},{"key":"2771_CR11","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1016\/S0735-1097(01)01184-6","volume":"37","author":"JK Song","year":"2001","unstructured":"Song JK, Kim HS, Kang DH, Lim TH, Song MG, Choi KJ, Hong MK, Park SW, Park SJ (2001) Different clinical features of aortic intramural hematoma versus dissection involving the ascending aorta. J Am Coll Cardiol 37:1604\u20131610","journal-title":"J Am Coll Cardiol"},{"key":"2771_CR12","first-page":"199","volume":"28","author":"E Mart\u00edn-Guti\u00e9rrez","year":"2021","unstructured":"Mart\u00edn-Guti\u00e9rrez E, Gualis-Cardona J, Maiorano P, Castillo-Pardo L, Laguna-N\u00fa\u00f1ez G, Casta\u00f1o-Ruiz M (2021) Tratamiento conservador vs. quir\u00fargico en el hematoma intramural agudo tipo A: revisi\u00f3n bibliogr\u00e1fica, metaan\u00e1lisis y an\u00e1lisis de diferencias temporales y geogr\u00e1ficas. Cir Cardiov 28:199\u2013209","journal-title":"Cir Cardiov"},{"key":"2771_CR13","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s11748-019-01068-9","volume":"67","author":"H Shimizu","year":"2019","unstructured":"Shimizu H, Endo S, Natsugoe S, Arai H, Araki Y, Oshima H, Fujii Y, Hanada H, Hirata Y, Kobayashi J, Komori K, Miyata H, Motomura N, Okita Y, Otsuji Y, Saiki Y, Shiiya N, Suma H, Takamoto S, Takeda S, Takanashi S, Yaku H, Yoshida K (2019) Thoracic and cardiovascular surgery in Japan during 2016. Gen Thorac Cardiovasc Surg 67:377\u2013411","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"2771_CR14","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1093\/ejcts\/ezx214","volume":"52","author":"M Larsen","year":"2017","unstructured":"Larsen M, Trimarchi S, Patel HJ, Tsai TT, Myrmel T, O\u2019Gara PT, Peterson MD, Hughes GC, McDonald ML, Froehlich JB, Isselbacher EM, Eagle KA, Nienaber CA, Montgomery DG, Di Eusanio M, Sundt TM, Bossone E, Pyeritz RE, Braverman AC, Deeb GM, Bavaria JE, Svensson LG, Gleason TG, Schermerhorn ML, Fillinger MF, Patel VI, Landon BE, Williams DM, Upchurch GR Jr (2017) Extended versus limited arch replacement in acute type A aortic dissection. Eur J Cardiothorac Surg 52:1104\u20131110","journal-title":"Eur J Cardiothorac Surg"},{"key":"2771_CR15","doi-asserted-by":"publisher","first-page":"6604","DOI":"10.21037\/jtd-23-1137","volume":"15","author":"F Nappi","year":"2023","unstructured":"Nappi F, Gambardella I, Singh SSA, Salsano A, Santini F, Spadaccio C, Biancari F, Dominguez J, Fiore A (2023) Survival following acute type A aortic dissection: a multicenter study. J Thorac Dis 15:6604\u20136622","journal-title":"J Thorac Dis"},{"key":"2771_CR16","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1186\/s12872-021-02104-4","volume":"21","author":"J Yang","year":"2021","unstructured":"Yang J, Yu C, Li X, Kuang J, Chen Z, Xiao F, Sun T, Fang M, Fan R (2021) Therapeutic management of acute type A aortic intramural hematoma. BMC Cardiovasc Disord 21:286","journal-title":"BMC Cardiovasc Disord"},{"key":"2771_CR17","doi-asserted-by":"publisher","first-page":"518","DOI":"10.21037\/acs.2019.08.07","volume":"8","author":"DH Tian","year":"2019","unstructured":"Tian DH, Chakos A, Hirst L, Chung STW, Yan TD (2019) Surgery for type A intramural hematoma: a systematic review of clinical outcomes. Ann Cardiothorac Surg 8:518\u2013523","journal-title":"Ann Cardiothorac Surg"},{"key":"2771_CR18","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1016\/j.jvs.2013.10.104","volume":"59","author":"RC Lo","year":"2014","unstructured":"Lo RC, Lu B, Fokkema MT, Conrad M, Patel VI, Fillinger M, Watkins MT, Schermerhorn ML (2014) Relative importance of aneurysm diameter and body size for predicting abdominal aortic aneurysm rupture in men and women. J Vasc Surg 59:1209\u20131216","journal-title":"J Vasc Surg"},{"key":"2771_CR19","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.athoracsur.2005.06.026","volume":"81","author":"RR Davies","year":"2006","unstructured":"Davies RR, Gallo A, Coady MA, Tellides G, Botta DM Jr, Burke B, Coe MP, Kopf GS, Elefteriades JA (2006) Novel measurement of relative aortic size predicts rupture of thoracic aortic aneurysms. Ann Thorac Surg 81:169\u2013177","journal-title":"Ann Thorac Surg"},{"key":"2771_CR20","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s11748-023-01967-y","volume":"72","author":"T Kitamura","year":"2024","unstructured":"Kitamura T, Fukuzumi M, Mishima O, Shikata F, Motoji Y, Tamura Y, Takahashi T, Morimoto Y, Kadohama T, Takagi D, Takahashi K, Shiiya N (2024) Watch and wait strategy for selected patients with type A intramural hematoma. Gen Thorac Cardiovasc Surg 72:225\u2013231","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"2771_CR21","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.athoracsur.2022.12.016","volume":"116","author":"RZ Vieira","year":"2023","unstructured":"Vieira RZ, Ghazanfari SY, An Y, Luong C, Tan M, Safi HJ, Estrera AL, Sandhu HK (2023) Contemporary midterm outcomes after primary repair of chronic type A aortic dissection. Ann Thorac Surg 116:459\u2013466","journal-title":"Ann Thorac Surg"}],"container-title":["Heart and Vessels"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-026-02771-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00380-026-02771-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00380-026-02771-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:46:53Z","timestamp":1790646413000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00380-026-02771-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":21,"alternative-id":["2771"],"URL":"https:\/\/doi.org\/10.1007\/s00380-026-02771-3","relation":{},"ISSN":["0910-8327","1615-2573"],"issn-type":[{"value":"0910-8327","type":"print"},{"value":"1615-2573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"assertion":[{"value":"21 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study protocol was approved by the Institutional Review Board of Kitasato University School of Medicine (approval No. B23-093) and the ethics committees of all participating centers, with informed consent waived due to the retrospective nature of the study. Detailed ethical statements are described in the Methods section. This study was conducted in accordance with the principles of the Declaration of Helsinki.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}