{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:41:28Z","timestamp":1771062088596,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T00:00:00Z","timestamp":1160006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Childs Nerv Syst"],"published-print":{"date-parts":[[2007,1,2]]},"DOI":"10.1007\/s00381-006-0199-z","type":"journal-article","created":{"date-parts":[[2006,10,4]],"date-time":"2006-10-04T15:07:09Z","timestamp":1159974429000},"page":"185-193","source":"Crossref","is-referenced-by-count":18,"title":["Diffuse high-grade gliomas as second malignant neoplasms after radio-chemotherapy for pediatric malignancies"],"prefix":"10.1007","volume":"23","author":[{"given":"Bernd F. M.","family":"Romeike","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoo-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolf-Ingo","family":"Steudel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Graf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,10,5]]},"reference":[{"key":"199_CR1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s00401-004-0873-8","volume":"108","author":"I Bl\u00fcmcke","year":"2004","unstructured":"Bl\u00fcmcke I, M\u00fcller S, Buslei R, Riederer BM, Wiestler OD (2004) Microtubule-associated protein-2 immunoreactivity: a useful tool in the differential diagnosis of low-grade neuroepithelial tumors. Acta Neuropathol 108:89\u201396","journal-title":"Acta Neuropathol"},{"key":"199_CR2","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/S0002-9440(10)65397-7","volume":"154","author":"DJ Brat","year":"1999","unstructured":"Brat DJ, James CD, Jedlicka AE, Connolly DC, Chang E, Castellani RJ, Schmid M, Schiller M, Carson DA, Burger PC (1999) Molecular genetic alterations in radiation-induced astrocytomas. Am J Pathol 154:1431\u20131438","journal-title":"Am J Pathol"},{"key":"199_CR3","doi-asserted-by":"crossref","first-page":"767","DOI":"10.3171\/jns.1993.78.5.0767","volume":"78","author":"BC Devaux","year":"1993","unstructured":"Devaux BC, O\u2019Fallon JR, Kelly PJ (1993) Resection, biopsy, and survival in malignant glial neoplasms. A retrospective study of clinical parameters, therapy, and outcome. J Neurosurg 78:767\u2013775","journal-title":"J Neurosurg"},{"key":"199_CR4","doi-asserted-by":"crossref","first-page":"442","DOI":"10.3171\/jns.1976.44.4.0442","volume":"44","author":"GJ Dohrmann","year":"1976","unstructured":"Dohrmann GJ, Farwell JR, Flannery JT (1976) Glioblastoma multiforme in children. J Neurosurg 44:442\u2013448","journal-title":"J Neurosurg"},{"key":"199_CR5","first-page":"133","volume":"29","author":"J Farwell","year":"1984","unstructured":"Farwell J, Dohrmann GJ, Flannery JT (1984) Tumors of the central nervous system in adolescents. Am Fam Phys 29:133\u2013139","journal-title":"Am Fam Phys"},{"key":"199_CR6","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/1097-0215(20001115)88:4<672::AID-IJC24>3.0.CO;2-N","volume":"88","author":"S Garwicz","year":"2000","unstructured":"Garwicz S, Anderson H, Olsen JH, Dollner H, Hertz H, Jonmundsson G, Langmark F, Lanning M, Moller T, Sankila R, Tulinius H (2000) Second malignant neoplasms after cancer in childhood and adolescence: a population-based case-control study in the 5 Nordic countries. The Nordic Society for Pediatric Hematology and Oncology. The Association of the Nordic Cancer Registries. Int J Cancer 88:672\u2013678","journal-title":"Int J Cancer"},{"key":"199_CR7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1126\/science.1905840","volume":"253","author":"M Hollstein","year":"1991","unstructured":"Hollstein M, Sidransky D, Vogelstein B, Harris CC (1991) p53 mutations in human cancers. Science 253:49\u201353","journal-title":"Science"},{"key":"199_CR8","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/s00381-003-0798-x","volume":"20","author":"M Kantar","year":"2004","unstructured":"Kantar M, Cetingul N, Kansoy S, Anacak Y, Demirtas E, Ersahin Y, Mutluer S (2004) Radiotherapy-induced secondary cranial neoplasms in children. Childs Nerv Syst 20:46\u201349","journal-title":"Childs Nerv Syst"},{"key":"199_CR9","first-page":"67","volume":"25","author":"YJ Kim","year":"2006","unstructured":"Kim YJ, Romeike BFM, Uszkoreit J, Feiden W (2006) Automatic method for nuclear segmentation in the determination of Ki-67 labelling index in meningiomas. Clin Neuropathol 25:67\u201373","journal-title":"Clin Neuropathol"},{"key":"199_CR10","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3171\/jns.1989.70.3.0469","volume":"70","author":"C Kitanaka","year":"1989","unstructured":"Kitanaka C, Shitara N, Nakagomi T, Nakamura H, Genka S, Nakagawa K, Akanuma A, Aoyama H, Takakura K (1989) Postradiation astrocytoma. Report of two cases. J Neurosurg 70:469\u2013474","journal-title":"J Neurosurg"},{"key":"199_CR11","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/S0959-8049(02)00875-4","volume":"39","author":"G Klein","year":"2003","unstructured":"Klein G, Michaelis J, Spix C, Wibbing R, Eggers G, Ritter J, Kaatsch P (2003) Second malignant neoplasms after treatment of childhood cancer. Eur J Cancer 39:808\u2013817","journal-title":"Eur J Cancer"},{"issue":"9071","key":"199_CR12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0140-6736(97)01116-1","volume":"350","author":"SJ Kony","year":"1997","unstructured":"Kony SJ, de Vathaire F, Chompret A, Shamsaldim A, Grimaud E, Raquin MA, Oberlin O, Brugieres L, Feunteun J, Eschwege F, Chavaudra J, Lemerle J, Bonaiti-Pellie C (1997) Radiation and genetic factors in the risk of second malignant neoplasms after a first cancer in childhood. Lancet 350(9071):91\u201395","journal-title":"Lancet"},{"key":"199_CR13","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1182\/blood.V95.9.2770.009k16_2770_2775","volume":"95","author":"L L\u00f6ning","year":"2000","unstructured":"L\u00f6ning L, Zimmermann M, Reiter A, Kaatsch P, Henze G, Riehm H, Schrappe M (2000) Secondary neoplasms subsequent to Berlin\u2013Frankfurt\u2013M\u00fcnster therapy of acute lymphoblastic leukemia in childhood: significantly lower risk without cranial radiotherapy. Blood 95:2770\u20132775","journal-title":"Blood"},{"key":"199_CR14","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00381-003-0850-x","volume":"20","author":"R Malde","year":"2004","unstructured":"Malde R, Jalali R, Muzumdar D, Shet T, Kurkure P (2004) Gliosarcoma occurring 8\u00a0years after treatment for a medulloblastoma. Childs Nerv Syst 20:243\u2013246","journal-title":"Childs Nerv Syst"},{"key":"199_CR15","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1056\/NEJM199111073251902","volume":"325","author":"JP Neglia","year":"1991","unstructured":"Neglia JP, Meadows AT, Robison LL, Kim TH, Newton WA, Ruymann FB, Sather HN, Hammond GD (1991) Second neoplasms after acute lymphoblastic leukemia in childhood. N Engl J Med 325:1330\u20131336","journal-title":"N Engl J Med"},{"key":"199_CR16","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/s007010050177","volume":"140","author":"S Nishio","year":"1998","unstructured":"Nishio S, Morioka T, Inamura T, Takeshita I, Fukui M, Sasaki M, Nakamura K, Wakisaka S (1998) Radiation-induced brain tumours: potential late complications of radiation therapy for brain tumours. Acta Neurochir (Wien) 140:763\u2013770","journal-title":"Acta Neurochir (Wien)"},{"key":"199_CR17","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/BF00271927","volume":"4","author":"L Palma","year":"1988","unstructured":"Palma L, Vagnozzi R, Annino L, Ciapetta P, Maleci A, Cantore G (1988) Post-radiation glioma in a child. Case report and review of the literature. Childs Nerv Syst 4:296\u2013301","journal-title":"Childs Nerv Syst"},{"key":"199_CR18","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1227\/00006123-198005000-00009","volume":"6","author":"GS Pearl","year":"1980","unstructured":"Pearl GS, Mirra SS, Miles ML (1980) Glioblastoma multiforme occurring 13\u00a0years after treatment of a medulloblastoma. Neurosurgery 6:546\u2013551","journal-title":"Neurosurgery"},{"key":"199_CR19","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1056\/NEJMoa035091","volume":"349","author":"CH Pui","year":"2003","unstructured":"Pui CH, Cheng C, Leung W, Rai SN, Rivera GK, Sandlund JT, Ribeiro RC, Relling MV, Kun LE, Evans WE, Hudson MM (2003) Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 349:640\u2013649","journal-title":"N Engl J Med"},{"key":"199_CR20","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0140-6736(98)11079-6","volume":"354","author":"MV Relling","year":"1999","unstructured":"Relling MV, Rubnitz JE, Rivera GK, Boyett JM, Hancock ML, Felix CA, Kun LE, Walter AW, Evans WE, Pui CH (1999) High incidence of secondary brain tumours after radiotherapy and antimetabolites. Lancet 354:34\u201339","journal-title":"Lancet"},{"key":"199_CR21","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1056\/NEJM198810203191601","volume":"319","author":"E Ron","year":"1988","unstructured":"Ron E, Modan B, Boice JD Jr, Alfandary E, Stovall M, Chetrit A, Katz L (1988) Tumors of the brain and nervous system after radiotherapy in childhood. N Engl J Med 319:1033\u20131039","journal-title":"N Engl J Med"},{"key":"199_CR22","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/1097-0142(19910115)67:2<392::AID-CNCR2820670213>3.0.CO;2-V","volume":"67","author":"M Salvati","year":"1991","unstructured":"Salvati M, Artico M, Caruso R, Rocchi G, Orlando ER, Nucci F (1991) A report on radiation-induced gliomas. Cancer 67:392\u2013397","journal-title":"Cancer"},{"key":"199_CR23","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0090-3019(03)00137-X","volume":"60","author":"M Salvati","year":"2003","unstructured":"Salvati M, Frati A, Russo N, Caroli E, Polli FM, Minniti G, Delfini R (2003) Radiation-induced gliomas: report of 10 cases and review of the literature. Surg Neurol 60:60\u201367","journal-title":"Surg Neurol"},{"key":"199_CR24","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/00043426-200110000-00008","volume":"23","author":"T Stavrou","year":"2001","unstructured":"Stavrou T, Bromley CM, Nicholson HS, Byrne J, Packer RJ, Goldstein AM, Reaman GH (2001) Prognostic factors and secondary malignancies in childhood medulloblastoma. J Pediatr Hematol\/Oncol 23:431\u2013436","journal-title":"J Pediatr Hematol\/Oncol"},{"key":"199_CR25","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00006123-199702000-00034","volume":"40","author":"M Tada","year":"1997","unstructured":"Tada M, Sawamura Y, Abe H, Iggo R (1997) Homozygous p53 gene mutation in a radiation-induced glioblastoma 10\u00a0years after treatment for an intracranial germ cell tumor: case report. Neurosurgery 40:393\u2013396","journal-title":"Neurosurgery"},{"key":"199_CR26","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1002\/1097-0142(19931001)72:7<2227::AID-CNCR2820720727>3.0.CO;2-I","volume":"72","author":"RW Tsang","year":"1993","unstructured":"Tsang RW, Laperriere NJ, Simpson WJ, Brierley J, Panzarella T, Smyth HS (1993) Glioma arising after radiation therapy for pituitary adenoma. A report of four patients and estimation of risk. Cancer 72:2227\u20132233","journal-title":"Cancer"},{"key":"199_CR27","first-page":"417","volume":"102","author":"SY Yang","year":"2005","unstructured":"Yang SY, Wang KC, Cho BK, Kim YY, Lim SY, Park SH, Kim IH, Kim SK (2005) Radiation-induced cerebellar glioblastoma at the site of a treated medulloblastoma: case report. J Neurosurg 102:417\u2013422","journal-title":"J Neurosurg"}],"container-title":["Child's Nervous System"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-006-0199-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00381-006-0199-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-006-0199-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T02:18:05Z","timestamp":1683598685000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00381-006-0199-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,5]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,1,2]]}},"alternative-id":["199"],"URL":"https:\/\/doi.org\/10.1007\/s00381-006-0199-z","relation":{},"ISSN":["0256-7040","1433-0350"],"issn-type":[{"value":"0256-7040","type":"print"},{"value":"1433-0350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,5]]}}}