{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T06:21:03Z","timestamp":1791699663951,"version":"4.3.4"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T00:00:00Z","timestamp":1368662400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Childs Nerv Syst"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1007\/s00381-013-2138-0","type":"journal-article","created":{"date-parts":[[2013,5,15]],"date-time":"2013-05-15T11:34:24Z","timestamp":1368617664000},"page":"2281-2286","source":"Crossref","is-referenced-by-count":18,"title":["Assessment of peripapillary retinal nerve fiber layer thickness in children with vitamin B12 deficiency"],"prefix":"10.1007","volume":"29","author":[{"given":"Serdar","family":"\u00d6zkasap","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kemal","family":"T\u00fcrkyilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"Dereci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veysi","family":"\u00d6ner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba","family":"Calapo\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Medine Cumhur","family":"C\u00fcre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Durmu\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,5,16]]},"reference":[{"issue":"10","key":"2138_CR1","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1212\/WNL.26.10.905","volume":"26","author":"DP Agamanolis","year":"1976","unstructured":"Agamanolis DP, Chester EM, Victor M, Kark JA, Hines JD, Harris JW (1976) Neuropathology of experimental vitamin B12 deficiency in monkeys. Neurology 26(10):905\u2013914","journal-title":"Neurology"},{"key":"2138_CR2","doi-asserted-by":"crossref","first-page":"693","DOI":"10.3945\/ajcn.2008.26947A","volume":"89","author":"LH Allen","year":"2009","unstructured":"Allen LH (2009) How common is vitamin B12 deficiency? Am J Clin Nutr 89:693\u2013696","journal-title":"Am J Clin Nutr"},{"key":"2138_CR3","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1177\/000992288702601211","volume":"26","author":"S Ashkenazi","year":"1987","unstructured":"Ashkenazi S, Weitz R, Varsano I, Mimouni M (1987) Vitamin B12 deficiency due to a strictly vegetarian diet in adolescence. Clin Pediatr (Phila) 26:662\u2013663","journal-title":"Clin Pediatr (Phila)"},{"key":"2138_CR4","first-page":"33","volume":"36","author":"WS Beck","year":"1991","unstructured":"Beck WS (1991) Neuropsychiatric consequences of cobalamin deficiency. Adv Intern Med 36:33\u201356","journal-title":"Adv Intern Med"},{"key":"2138_CR5","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1167\/iovs.06-1029","volume":"48","author":"F Berisha","year":"2007","unstructured":"Berisha F, Feke GT, Trempe CL, McMeel JW, Schepens CL (2007) Retinal abnormalities in early Alzheimer\u2019s disease. Invest Ophthalmol Vis Sci 48:2285\u20132289","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"2138_CR6","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1177\/15648265080292S117","volume":"29","author":"MM Black","year":"2008","unstructured":"Black MM (2008) Effects of vitamin B12 and folate deficiency on brain development in children. Food Nutr Bull 29(2):126\u2013131","journal-title":"Food Nutr Bull"},{"issue":"6","key":"2138_CR7","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1182\/blood-2008-03-040253","volume":"112","author":"R Carmel","year":"2008","unstructured":"Carmel R (2008) How I treat cobalamin (vitamin B12) deficiency. Blood 112(6):2214\u20132221","journal-title":"Blood"},{"key":"2138_CR8","first-page":"454","volume":"109","author":"R Carmel","year":"1987","unstructured":"Carmel R, Sinow RM, Karnaze DS (1987) Atypical cobalamin deficiency. Subtle biochemical evidence of deficiency is commonly demonstrable in patients without megaloblastic anemia and is often associated with protein-bound cobalamin malabsorption. J Lab Clin Med 109:454\u2013463","journal-title":"J Lab Clin Med"},{"issue":"1","key":"2138_CR9","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1600-0404.1980.tb02991.x","volume":"61","author":"EM Chester","year":"1980","unstructured":"Chester EM, Agamanolis DP, Harris JW, Victor M, Hines JD, Kark JA (1980) Optic atrophy in experimental vitamin B12 deficiency in monkeys. Acta Neurol Scand 61(1):9\u201326","journal-title":"Acta Neurol Scand"},{"key":"2138_CR10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/qjmed\/hcn138","volume":"102","author":"N Dali-Youcef","year":"2009","unstructured":"Dali-Youcef N, Andres E (2009) An update on cobalamin deficiency in adults. QJM 102:17\u201328","journal-title":"QJM"},{"key":"2138_CR11","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/ajcn\/85.2.614S","volume":"85","author":"MK Georgieff","year":"2007","unstructured":"Georgieff MK (2007) Nutrition and the developing brain: nutrient priorities and measurement. Am J Clin Nutr 85:614\u2013620","journal-title":"Am J Clin Nutr"},{"key":"2138_CR12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/00005792-199107000-00001","volume":"70","author":"EB Healton","year":"1991","unstructured":"Healton EB, Savage DG, Brust JCM, Garrett TJ, Lindenbaum J (1991) Neurologic aspects of cobalamin deficiency. Medicine 70:229\u2013245","journal-title":"Medicine"},{"key":"2138_CR13","first-page":"1506","volume":"91","author":"AM Hvas","year":"2006","unstructured":"Hvas AM, Nexo E (2006) Diagnosis and treatment of vitamin B12 deficiency. an update. Haematologica 91:1506\u20131512","journal-title":"Haematologica"},{"key":"2138_CR14","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1016\/j.visres.2004.06.009","volume":"944","author":"R Inzelberg","year":"2004","unstructured":"Inzelberg R, Ramirez JA, Nisipeanu P, Ophir A (2004) Retinal nerve fiber layer thinning in Parkinson\u2019s disease. Vision Res 944:2793\u20132797","journal-title":"Vision Res"},{"issue":"10","key":"2138_CR15","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1111\/j.1368-5031.2004.00306.x","volume":"58","author":"AJ Larner","year":"2004","unstructured":"Larner AJ (2004) Visual failure caused by vitamin B12 deficiency optic neuropathy. Int J Clin Pract 58(10):977\u2013978","journal-title":"Int J Clin Pract"},{"key":"2138_CR16","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1056\/NEJM198806303182604","volume":"318","author":"J Lindenbaum","year":"1988","unstructured":"Lindenbaum J, Healton EB, Savage DG, Brust JC, Garrett TJ, Podell ER, Marcell PD, Stabler SP, Allen RH (1988) Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 318:1720\u20131728","journal-title":"N Engl J Med"},{"key":"2138_CR17","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/ajh.2830340205","volume":"34","author":"J Lindenbaum","year":"1990","unstructured":"Lindenbaum J, Savage DG, Stabler SP, Allen RH (1990) Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations. Am J Hematol 34:99\u2013107","journal-title":"Am J Hematol"},{"key":"2138_CR18","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1093\/ajcn\/72.3.762","volume":"72","author":"MW Louwman","year":"2000","unstructured":"Louwman MW, van Dusseldorp M, van de Vijver FJ, Thomas CM, Schneede J, Ueland PM, Refsum H, van Staveren WA (2000) Signs of impaired cognitive function in adolescents with marginal cobalamin status. Am J Clin Nutr 72:762\u2013769","journal-title":"Am J Clin Nutr"},{"key":"2138_CR19","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s002470050090","volume":"27","author":"K Lovblad","year":"1997","unstructured":"Lovblad K, Ramelli G, Remonda L, Nirkko AC, Ozdoba C, Schroth G (1997) Retardation of myelination due to dietary vitamin B12 deficiency: cranial MRI findings. Pediatr Radiol 27:155\u2013158","journal-title":"Pediatr Radiol"},{"issue":"1","key":"2138_CR20","first-page":"57","volume":"43","author":"UK Misra","year":"2003","unstructured":"Misra UK, Kalita J, Das A (2003) Vitamin B12 deficiency neurological syndromes: a clinical, MRI, and electrodiagnostic study. Electromyogr Clin Neurophysiol 43(1):57\u201364","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"2138_CR21","doi-asserted-by":"crossref","first-page":"309","DOI":"10.3122\/jabfm.17.5.309","volume":"17","author":"JW Mold","year":"2004","unstructured":"Mold JW, Vesely SK, Keyl BA, Schenk JB, Roberts M (2004) The prevalence, predictors, and consequences of peripheral sensory neuropathy in older patients. J Am Board Fam Pract 17:309\u2013318","journal-title":"J Am Board Fam Pract"},{"key":"2138_CR22","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1364\/OPEX.12.000367","volume":"12","author":"N Nassif","year":"2004","unstructured":"Nassif N, Cense B, Park B, Pierce M, Yun S, Bouma B (2004) In vivo high resolution video-rate spectral domain optical coherence tomography of the human retina and optic nerve. Opt Express 12:367\u2013376","journal-title":"Opt Express"},{"issue":"4","key":"2138_CR23","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.clinph.2003.11.013","volume":"115","author":"S Pandey","year":"2004","unstructured":"Pandey S, Kalita J, Misra UK (2004) A sequential study of visual evoked potential in patients with vitamin B12 deficiency neurological syndrome. Clin Neurophysiol 115(4):914\u2013918","journal-title":"Clin Neurophysiol"},{"key":"2138_CR24","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/j.1755-3768.2009.01527.x","volume":"88","author":"V Pueyo","year":"2010","unstructured":"Pueyo V, Ara JR, Almarcegui C, Martin J, G\u00fcerri N, Garc\u00eda E, Pablo LE, Honrubia FM, Fernandez FJ (2010) Subclinical atrophy of the retinal nerve fiber layer in multiple sclerosis. Acta Ophthalmol 88:748\u2013752","journal-title":"Acta Ophthalmol"},{"issue":"5","key":"2138_CR25","first-page":"273","volume":"45","author":"V Puri","year":"2005","unstructured":"Puri V, Chaudhry N, Goel S, Gulati P, Nehru R, Chowdhury D (2005) Vitamin B12 deficiency: a clinical and electrophysiological profile. Electromyogr Clin Neurophysiol 45(5):273\u2013284","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"2138_CR26","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1067\/mpd.2001.112160","volume":"138","author":"SA Rasmussen","year":"2001","unstructured":"Rasmussen SA, Fernhoff PM, Scanlon KS (2001) Vitamin B12 deficiency in children and adolescents. J Pediatr 138:10\u201317","journal-title":"J Pediatr"},{"key":"2138_CR27","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.pneurobio.2009.04.004","volume":"88","author":"G Scalabrino","year":"2009","unstructured":"Scalabrino G (2009) The multifaceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: lessons learned from its deficiency. Prog Neurobiol 88:203\u2013220","journal-title":"Prog Neurobiol"},{"issue":"2","key":"2138_CR28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/15648265080292S103","volume":"29","author":"B Shane","year":"2008","unstructured":"Shane B (2008) Folate and vitamin B12 metabolism: overview and interaction with riboflavin, vitamin B6, and polymorphisms. Food Nutr Bull 29(2):5\u201316","journal-title":"Food Nutr Bull"},{"key":"2138_CR29","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0022-510X(98)00005-7","volume":"156","author":"G Tredici","year":"1998","unstructured":"Tredici G, Buccellato FR, Braga M, Cavaletti G, Ciscato P, Moggio M, Scalabrino G (1998) Polyneuropathy due to cobalamin deficiency in the rat. J Neurol Sci 156:18\u201329","journal-title":"J Neurol Sci"},{"key":"2138_CR30","author":"K T\u00fcrky\u0131lmaz","year":"2013","unstructured":"T\u00fcrky\u0131lmaz K, \u00d6ner V, T\u00fcrky\u0131lmaz AK, K\u0131rba\u015f A, K\u0131rba\u015f S, Sekeryapan B (2013) Evaluation of peripapillary retinal nerve fiber layer thickness in patients with vitamin B12 deficiency using spectral domain optical coherence tomography. Curr Eye Res. doi: 10.3109\/02713683.2012.758291","journal-title":"Curr Eye Res"},{"key":"2138_CR31","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1093\/ajcn\/69.4.664","volume":"69","author":"M Dusseldorp van","year":"1999","unstructured":"van Dusseldorp M, Schneede J, Refsum H, Ueland PM, Thomas CM, de Boer E, van Staveren WA (1999) Risk of persistent cobalamin deficiency in adolescents fed a macrobiotic diet in early life. Am J Clin Nutr 69:664\u2013671","journal-title":"Am J Clin Nutr"},{"key":"2138_CR32","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1136\/adc.77.2.137","volume":"77","author":"U Schenck von","year":"1997","unstructured":"von Schenck U, Bender-Gotze C, Koletzko B (1997) Persistence of neurological damage induced by dietary vitamin B12 deficiency in infancy. Arch Dis Child 77:137\u2013139","journal-title":"Arch Dis Child"},{"key":"2138_CR33","first-page":"419","volume-title":"Nathan and Oski\u2019s hematology of infancy and childhood","author":"VM Whitehead","year":"2003","unstructured":"Whitehead VM, Rosenblatt DS, Cooper BA (2003) Megaloblastic anemia. In: Nathan DG, Orkin SH, Ginsburg D, Look AT (eds) Nathan and Oski\u2019s hematology of infancy and childhood, 6th edn. WB Saunders, Philadelphia, pp 419\u2013455","edition":"6"},{"key":"2138_CR34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5694\/j.1326-5377.1979.tb112643.x","volume":"2","author":"MC Wighton","year":"1979","unstructured":"Wighton MC, Manson JI, Speed I, Robertson E, Chapman E (1979) Brain damage in infancy and dietary vitamin B12 deficiency. Med J Aust 2:1\u20133","journal-title":"Med J Aust"}],"container-title":["Child's Nervous System"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-013-2138-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00381-013-2138-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-013-2138-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T10:09:21Z","timestamp":1746007761000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00381-013-2138-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,16]]},"references-count":34,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["2138"],"URL":"https:\/\/doi.org\/10.1007\/s00381-013-2138-0","relation":{},"ISSN":["0256-7040","1433-0350"],"issn-type":[{"value":"0256-7040","type":"print"},{"value":"1433-0350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,16]]}}}