{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T14:00:25Z","timestamp":1793023225079,"version":"4.5.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T00:00:00Z","timestamp":1526342400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Childs Nerv Syst"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s00381-018-3826-6","type":"journal-article","created":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T20:52:58Z","timestamp":1526417578000},"page":"1511-1519","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Surgery for subependymal giant cell astrocytomas in children with tuberous sclerosis complex"],"prefix":"10.1007","volume":"34","author":[{"given":"Martine","family":"Fohlen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Ferrand-Sorbets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Delalande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Dorfm\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,15]]},"reference":[{"issue":"1","key":"3826_CR1","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.ejpn.2012.10.005","volume":"17","author":"S Amin","year":"2013","unstructured":"Amin S, Carter M, Edwards RJ, Pople I, Aquilina K, Merrifield J, Osborne JP, O'Callaghan FJK (2013) The outcome of surgical management of subependymal giant cell astrocytoma in tuberous sclerosis complex. Eur J Paediatr Neurol 17(1):36\u201344","journal-title":"Eur J Paediatr Neurol"},{"issue":"1","key":"3826_CR2","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1111\/j.1528-1167.2010.02777.x","volume":"52","author":"I Bl\u00fcmcke","year":"2011","unstructured":"Bl\u00fcmcke I, Thom M, Aronica E, Armstrong DD, Vinters HV, Palmini A, Jacques TS, Avanzini G, Barkovich AJ, Battaglia G, Becker A, Cepeda C, Cendes F, Colombo N, Crino P, Cross JH, Delalande O, Dubeau F, Duncan J, Guerrini R, Kahane P, Mathern G, Najm I, \u00d6zkara \u00c7, Raybaud C, Represa A, Roper SN, Salamon N, Schulze-Bonhage A, Tassi L, Vezzani A, Spreafico R (2011) The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission. Epilepsia 52(1):158\u2013174","journal-title":"Epilepsia"},{"issue":"4","key":"3826_CR3","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1007\/s11940-011-0123-z","volume":"13","author":"CJ Campen","year":"2011","unstructured":"Campen CJ, Porter BE (2011) Subependymal giant cell astrocytoma (SEGA) treatment update. Curr Treat Options Neurol 13(4):380\u2013385","journal-title":"Curr Treat Options Neurol"},{"issue":"1","key":"3826_CR4","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2006.20.1.6","volume":"20","author":"MJ Clarke","year":"2006","unstructured":"Clarke MJ, Foy AB, Wetjen N, Raffel C (2006) Imaging characteristics and growth of subependymal giant cell astrocytomas. Neurosurg Focus 20(1):E5","journal-title":"Neurosurg Focus"},{"issue":"4","key":"3826_CR5","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s00381-002-0700-2","volume":"19","author":"V Cuccia","year":"2003","unstructured":"Cuccia V, Zuccaro G, Sosa F, Monges J, Lubienieky F, Taratuto AL (2003) Subependymal giant cell astrocytoma in children with tuberous sclerosis. Childs Nerv Syst 19(4):232\u2013243","journal-title":"Childs Nerv Syst"},{"issue":"9","key":"3826_CR6","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/BF00261603","volume":"12","author":"P Curatolo","year":"1996","unstructured":"Curatolo P (1996) Neurological manifestations of tuberous sclerosis complex. Childs Nerv Syst 12(9):515\u2013521","journal-title":"Childs Nerv Syst"},{"issue":"7","key":"3826_CR7","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1177\/0883073810361789","volume":"25","author":"P Curatolo","year":"2010","unstructured":"Curatolo P, Napolioni V, Moavero R (2010) Autism spectrum disorders in tuberous sclerosis: pathogenetic pathways and implications for treatment. J Child Neurol 25(7):873\u2013880","journal-title":"J Child Neurol"},{"issue":"1","key":"3826_CR8","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1227\/01.NEU.0000249216.19591.5D","volume":"60","author":"S Ribaupierre De","year":"2007","unstructured":"De Ribaupierre S, Dorfm\u00fcller G, Bulteau C et al (2007) Subependymal giant-cell astrocytomas in pediatric tuberous sclerosis disease: when should we operate? Neurosurgery 60(1):83\u201389","journal-title":"Neurosurgery"},{"issue":"3","key":"3826_CR9","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1159\/000120947","volume":"23","author":"C Rocco Di","year":"1995","unstructured":"Di Rocco C, Iannelli A, Marchese E (1995) On the treatment of subependymal giant cell astrocytomas and associated hydrocephalus in tuberous sclerosis. Pediatr Neurosurg 23(3):115\u2013121","journal-title":"Pediatr Neurosurg"},{"issue":"7","key":"3826_CR10","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1016\/0092-8674(93)90618-Z","volume":"75","author":"European Chromosome 16 Tuberous Sclerosis Consortium","year":"1993","unstructured":"European Chromosome 16 Tuberous Sclerosis Consortium (1993) Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell 75(7):1305\u20131315","journal-title":"Cell"},{"issue":"9861","key":"3826_CR11","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/S0140-6736(12)61134-9","volume":"381","author":"DN Franz","year":"2013","unstructured":"Franz DN, Belousova E, Sparagana S, Bebin EM, Frost M, Kuperman R, Witt O, Kohrman MH, Flamini JR, Wu JY, Curatolo P, de Vries PJ, Whittemore VH, Thiele EA, Ford JP, Shah G, Cauwel H, Lebwohl D, Sahmoud T, Jozwiak S (2013) Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial. Lancet 381(9861):125\u2013132","journal-title":"Lancet"},{"issue":"1","key":"3826_CR12","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/BF00706730","volume":"1","author":"P Fr\u00e8rebeau","year":"1985","unstructured":"Fr\u00e8rebeau P, Benezech J, Segnarbieux F, Harbi H, Desy A, Marty-Double C (1985) Intraventricular tumors in tuberous sclerosis. Childs Nerv Syst 1(1):45\u201348","journal-title":"Childs Nerv Syst"},{"issue":"8","key":"3826_CR13","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1212\/01.WNL.0000142039.14522.1A","volume":"63","author":"S Goh","year":"2004","unstructured":"Goh S, Butler W, Thiele EA (2004) Subependymal giant cell tumors in tuberous sclerosis complex. Neurology 63(8):1457\u20131461","journal-title":"Neurology"},{"issue":"1","key":"3826_CR14","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3171\/2013.9.PEDS13193","volume":"13","author":"DH Harter","year":"2014","unstructured":"Harter DH, Bassani L, Rodgers SD, Roth J, Devinsky O, Carlson C, Wisoff JH, Weiner HL (2014) A management strategy for intraventricular subependymal giant cell astrocytomas in tuberous sclerosis complex. J Neurosurg Pediatr 13(1):21\u201328","journal-title":"J Neurosurg Pediatr"},{"issue":"2","key":"3826_CR15","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/BF01644066","volume":"3","author":"FJ Holanda","year":"1980","unstructured":"Holanda FJ, Holanda GM (1980) Tuberous sclerosis\u2014neurosurgical indications in intraventricular tumors. Neurosurg Rev 3(2):139\u2013150","journal-title":"Neurosurg Rev"},{"issue":"4","key":"3826_CR16","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.ejpn.2012.12.008","volume":"17","author":"S J\u00f3\u017awiak","year":"2013","unstructured":"J\u00f3\u017awiak S, Nabbout R, Curatolo P, participants of the TSC Consensus Meeting for SEGA and Epilepsy Management (2013) Management of subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC): clinical recommendations. Eur J Paediatr Neurol 17(4):348\u2013352","journal-title":"Eur J Paediatr Neurol"},{"issue":"3","key":"3826_CR17","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1023\/A:1010664311717","volume":"52","author":"SK Kim","year":"2001","unstructured":"Kim SK, Wang KC, Cho BK, Jung HW, Jin Lee Y, Seob Chung Y, Lee JY, Park SH, Kim YM, Choe G, Chi JG (2001) Biological behavior and tumorigenesis of subependymal giant cell astrocytomas. J Neuro-Oncol 52(3):217\u2013225","journal-title":"J Neuro-Oncol"},{"issue":"9","key":"3826_CR18","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1111\/j.1528-1157.2000.tb00327.x","volume":"41","author":"S Koh","year":"2000","unstructured":"Koh S, Jayakar P, Dunoyer C, Whiting SE, Resnick TJ, Alvarez LA, Morrison G, Ragheb J, Prats A, Dean P, Antel SB, Gilman J, Duchowny MS (2000) Epilepsy surgery in children with tuberous sclerosis complex: presurgical evaluation and outcome. Epilepsia 41(9):1206\u20131213","journal-title":"Epilepsia"},{"issue":"19","key":"3826_CR19","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1056\/NEJMoa1001671","volume":"363","author":"DA Krueger","year":"2010","unstructured":"Krueger DA, Care MM, Holland K, Agricola K, Tudor C, Mangeshkar P, Wilson KA, Byars A, Sahmoud T, Franz DN (2010) Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. N Engl J Med 363(19):1801\u20131811","journal-title":"N Engl J Med"},{"issue":"4","key":"3826_CR20","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1007\/s10143-004-0339-4","volume":"27","author":"R Kumar","year":"2004","unstructured":"Kumar R, Singh V (2004) Subependymal giant cell astrocytoma: a report of five cases. Neurosurg Rev 27(4):274\u2013280","journal-title":"Neurosurg Rev"},{"issue":"1","key":"3826_CR21","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000120217","volume":"12","author":"RL McLaurin","year":"1985","unstructured":"McLaurin RL, Towbin RB (1985\u20131986)) Tuberous sclerosis: diagnostic and surgical considerations. Pediatr Neurosci 12(1):43\u201348","journal-title":"Pediatr Neurosci"},{"issue":"3","key":"3826_CR22","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1136\/jnnp.66.3.370","volume":"66","author":"R Nabbout","year":"1999","unstructured":"Nabbout R, Santos M, Rolland Y, Delalande O, Dulac O, Chiron C (1999) Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis. J Neurol Neurosurg Psychiatry 66(3):370\u2013375","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"3826_CR23","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.braindev.2008.09.013","volume":"31","author":"V Napolioni","year":"2009","unstructured":"Napolioni V, Moavero R, Curatolo P (2009) Recent advances in neurobiology of tuberous sclerosis complex. Brain Dev 31(2):104\u2013113","journal-title":"Brain Dev"},{"issue":"1","key":"3826_CR24","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1054\/jocn.2000.0767","volume":"8","author":"S Nishio","year":"2001","unstructured":"Nishio S, Morioka T, Suzuki S, Kira R, Mihara F, Fukui M (2001) Subependymal giant cell astrocytoma: clinical and neuroimaging features of four cases. J Clin Neurosci 8(1):31\u201334","journal-title":"J Clin Neurosci"},{"key":"3826_CR25","unstructured":"Northrup H, Koenig MK, Pearson DA, Au KS (1999) In: Adam MP et al (ed) Tuberous sclerosis complex GeneReviews Seattle (WA): University of Washington, Seattle; 1993\u20132018"},{"issue":"4","key":"3826_CR26","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.pediatrneurol.2013.08.001","volume":"49","author":"H Northrup","year":"2013","unstructured":"Northrup H, Krueger DA, International Tuberous Sclerosis Complex Consensus Group (2013) Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference. Pediatr Neurol 49(4):243\u2013254","journal-title":"Pediatr Neurol"},{"issue":"9114","key":"3826_CR27","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.1016\/S0140-6736(05)78872-3","volume":"351","author":"FJ O\u2019Callaghan","year":"1998","unstructured":"O\u2019Callaghan FJ, Shiell AW, Osborne JP, Martyn CN (1998) Prevalence of tuberous sclerosis estimated by capture-recapture analysis. Lancet 351(9114):1490","journal-title":"Lancet"},{"issue":"6 Suppl 3","key":"3826_CR28","doi-asserted-by":"publisher","first-page":"S2","DOI":"10.1212\/01.WNL.0000114507.30388.7E","volume":"62","author":"A Palmini","year":"2004","unstructured":"Palmini A, Najm I, Avanzini G, Babb T, Guerrini R, Foldvary-Schaefer N, Jackson G, Luders HO, Prayson R, Spreafico R, Vinters HV (2004) Terminology and classification of the cortical dysplasias. Neurology 62(6 Suppl 3):S2\u2013S8","journal-title":"Neurology"},{"issue":"7","key":"3826_CR29","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s00381-013-2045-4","volume":"29","author":"H Ren","year":"2013","unstructured":"Ren H, Chen X, Sun G et al (2013) Resection of subependymal giant cell astrocytoma guided by intraoperative magnetic resonance imaging and neuronavigation. Childs Nerv Syst 29(7):113\u20131121","journal-title":"Childs Nerv Syst"},{"issue":"12","key":"3826_CR30","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1177\/088307389801301206","volume":"13","author":"ES Roach","year":"1998","unstructured":"Roach ES, Gomez MR, Northrup H (1998) Tuberous sclerosis complex consensus conference: revised clinical diagnostic criteria. J Child Neurol 13(12):624\u2013628","journal-title":"J Child Neurol"},{"issue":"6","key":"3826_CR31","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/BF00301665","volume":"11","author":"M Roszkowski","year":"1995","unstructured":"Roszkowski M, Drabik K, Barszcz S, Jozwiak S (1995) Surgical treatment of intraventricular tumors associated with tuberous sclerosis. Childs Nerv Syst 11(6):335\u2013339","journal-title":"Childs Nerv Syst"},{"issue":"6","key":"3826_CR32","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.pediatrneurol.2013.08.017","volume":"49","author":"J Roth","year":"2013","unstructured":"Roth J, Roach ES, Bartels U, J\u00f3\u017awiak S, Koenig MK, Weiner HL, Franz DN, Wang HZ (2013) Subependymal giant cell astrocytoma: diagnosis, screening, and treatment. Recommendations from the International Tuberous Sclerosis Complex Consensus Conference 2012. Pediatr Neurol 49(6):439\u2013444","journal-title":"Pediatr Neurol"},{"key":"3826_CR33","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1136\/jmg.26.1.28","volume":"26","author":"J Sampson","year":"1989","unstructured":"Sampson J, Scahill S, Stephenson J, Mann L, Connor J (1989) Genetic aspects of tuberous sclerosis in the west of Scotland. J Med Genet 26:28\u201331","journal-title":"J Med Genet"},{"issue":"4","key":"3826_CR34","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/BF03033764","volume":"10","author":"MC Sharma","year":"2004","unstructured":"Sharma MC, Ralte AM, Gaekwad S, Santosh V, Shankar SK, Sarkar C (2004) Subependymal giant cell astrocytoma\u2014a clinicopathological study of 23 cases with special emphasis on histogenesis. Pathol Oncol Res 10(4):219\u2013224","journal-title":"Pathol Oncol Res"},{"issue":"4","key":"3826_CR35","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1159\/000120796","volume":"20","author":"G Sinson","year":"1994","unstructured":"Sinson G, Sutton LN, Yachnis AT, Duhaime AC, Schut L (1994) Subependymal giant cell astrocytomas in children. Pediatr Neurosurg 20(4):233\u2013239","journal-title":"Pediatr Neurosurg"},{"issue":"4","key":"3826_CR36","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1177\/088307389801300405","volume":"13","author":"OA Torres","year":"1998","unstructured":"Torres OA, Roach ES, Delgado MR, Sparagana SP, Sheffield E, Swift D, Bruce D (1998) Early diagnosis of subependymal giant cell astrocytoma in patients with tuberous sclerosis. J Child Neurol 13(4):173\u2013177","journal-title":"J Child Neurol"},{"issue":"3","key":"3826_CR37","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/0303-8467(96)00028-5","volume":"98","author":"M Turgut","year":"1996","unstructured":"Turgut M, Akalan N, Ozgen T, Ruacan S, Erbengi A (1996) Subependymal giant cell astrocytoma associated with tuberous sclerosis: diagnostic and surgical characteristics of five cases with unusual features. Clin Neurol Neurosurg 98(3):217\u2013221","journal-title":"Clin Neurol Neurosurg"},{"key":"3826_CR38","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1126\/science.277.5327.805","volume":"277","author":"M Slegtenhorst Van","year":"1997","unstructured":"Van Slegtenhorst M, de Hoogt R, Hermans C et al (1997) Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science 277:805\u2013808","journal-title":"Science"}],"container-title":["Child's Nervous System"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00381-018-3826-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-018-3826-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-018-3826-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T01:07:10Z","timestamp":1604279230000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00381-018-3826-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,15]]},"references-count":38,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["3826"],"URL":"https:\/\/doi.org\/10.1007\/s00381-018-3826-6","relation":{},"ISSN":["0256-7040","1433-0350"],"issn-type":[{"value":"0256-7040","type":"print"},{"value":"1433-0350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,15]]},"assertion":[{"value":"23 November 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}