{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:45:55Z","timestamp":1787168755500,"version":"build-2736575974"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T00:00:00Z","timestamp":1586995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T00:00:00Z","timestamp":1586995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Childs Nerv Syst"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1007\/s00381-020-04601-x","type":"journal-article","created":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T14:04:45Z","timestamp":1587045885000},"page":"1357-1365","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Selective dorsal rhizotomy for spasticity of genetic etiology"],"prefix":"10.1007","volume":"36","author":[{"given":"Laura-Nanna","family":"Lohkamp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Coulter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George M.","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,4,16]]},"reference":[{"key":"4601_CR1","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1136\/archdischild-2014-306874","volume":"100","author":"K Aquilina","year":"2015","unstructured":"Aquilina K, Graham D, Wimalasundera N (2015) Selective dorsal rhizotomy: an old treatment re-emerging. Arch Dis Child 100:798\u2013802","journal-title":"Arch Dis Child"},{"key":"4601_CR2","doi-asserted-by":"publisher","first-page":"209","DOI":"10.21037\/qims.2018.01.08","volume":"8","author":"D Graham","year":"2018","unstructured":"Graham D, Aquilina K, Mankad K, Wimalasundera N (2018) Selective dorsal rhizotomy: current state of practice and the role of imaging. Quant Imaging Med Surg 8:209\u2013218","journal-title":"Quant Imaging Med Surg"},{"key":"4601_CR3","doi-asserted-by":"publisher","first-page":"E1205","DOI":"10.1503\/cmaj.191065","volume":"191","author":"B Davidson","year":"2019","unstructured":"Davidson B, Fehlings D, Milo-Manson G, Ibrahim GM (2019) Improving access to selective dorsal rhizotomy for children with cerebral palsy. CMAJ 191:E1205\u2013e1206","journal-title":"CMAJ"},{"key":"4601_CR4","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/S2352-4642(19)30119-1","volume":"3","author":"J Summers","year":"2019","unstructured":"Summers J, Coker B, Eddy S, Elstad M, Bunce C, Bourmpaki E, Pennington M, Aquilina K, Cawker S, Edwards R, Goodden J, Hawes S, McCune K, Pettorini B, Smith J, Sneade C, Vloeberghs M, Patrick H, Powell H, Verity C, Peacock JL (2019) Selective dorsal rhizotomy in ambulant children with cerebral palsy: an observational cohort study. Lancet Child Adolesc Health 3:455\u2013462","journal-title":"Lancet Child Adolesc Health"},{"key":"4601_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1017\/S0012162201001608","volume":"44","author":"J McLaughlin","year":"2002","unstructured":"McLaughlin J, Bjornson K, Temkin N, Steinbok P, Wright V, Reiner A, Roberts T, Drake J, O'Donnell M, Rosenbaum P, Barber J, Ferrel A (2002) Selective dorsal rhizotomy: meta-analysis of three randomized controlled trials. Dev Med Child Neurol 44:17\u201325","journal-title":"Dev Med Child Neurol"},{"key":"4601_CR6","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1111\/j.1469-8749.1997.tb07407.x","volume":"39","author":"P Steinbok","year":"1997","unstructured":"Steinbok P, Reiner AM, Beauchamp R, Armstrong RW, Cochrane DD, Kestle J (1997) A randomized clinical trial to compare selective posterior rhizotomy plus physiotherapy with physiotherapy alone in children with spastic diplegic cerebral palsy. Dev Med Child Neurol 39:178\u2013184","journal-title":"Dev Med Child Neurol"},{"key":"4601_CR7","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1111\/j.1469-8749.1998.tb15456.x","volume":"40","author":"FV Wright","year":"1998","unstructured":"Wright FV, Sheil EM, Drake JM, Wedge JH, Naumann S (1998) Evaluation of selective dorsal rhizotomy for the reduction of spasticity in cerebral palsy: a randomized controlled trial. Dev Med Child Neurol 40:239\u2013247","journal-title":"Dev Med Child Neurol"},{"key":"4601_CR8","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1111\/j.1469-8749.1994.tb08187.x","volume":"36","author":"JF McLaughlin","year":"1994","unstructured":"McLaughlin JF, Bjornson KF, Astley SJ, Hays RM, Hoffinger SA, Armantrout EA, Roberts TS (1994) The role of selective dorsal rhizotomy in cerebral palsy: critical evaluation of a prospective clinical series. Dev Med Child Neurol 36:755\u2013769","journal-title":"Dev Med Child Neurol"},{"key":"4601_CR9","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1590\/1984-0462\/;2018;36;1;00005","volume":"36","author":"RD Nicolini-Panisson","year":"2018","unstructured":"Nicolini-Panisson RD, Tedesco AP, Folle MR, Donadio MVF (2018) Selective dorsal rhizotomy in cerebral palsy: selection criteria and postoperative physical therapy protocols. Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo 36:9","journal-title":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo"},{"key":"4601_CR10","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ridd.2014.11.012","volume":"37","author":"JF Funk","year":"2015","unstructured":"Funk JF, Panthen A, Bakir MS, Gruschke F, Sarpong A, Wagner C, Lebek S, Haberl EJ (2015) Predictors for the benefit of selective dorsal rhizotomy. Res Dev Disabil 37:127\u2013134","journal-title":"Res Dev Disabil"},{"key":"4601_CR11","doi-asserted-by":"publisher","first-page":"E6","DOI":"10.3171\/2013.8.FOCUS13294","volume":"35","author":"WC Gump","year":"2013","unstructured":"Gump WC, Mutchnick IS, Moriarty TM (2013) Selective dorsal rhizotomy for spasticity not associated with cerebral palsy: reconsideration of surgical inclusion criteria. Neurosurg Focus 35:E6","journal-title":"Neurosurg Focus"},{"key":"4601_CR12","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1055\/s-0034-1386767","volume":"34","author":"JK Fink","year":"2014","unstructured":"Fink JK (2014) Hereditary spastic paraplegia: clinical principles and genetic advances. Semin Neurol 34:293\u2013305","journal-title":"Semin Neurol"},{"key":"4601_CR13","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.ejpn.2013.09.009","volume":"18","author":"L Racis","year":"2014","unstructured":"Racis L, Tessa A, Pugliatti M, Storti E, Agnetti V, Santorelli FM (2014) Infantile-onset ascending hereditary spastic paralysis: a case report and brief literature review. Eur J Paediatr Neurol 18:235\u2013239","journal-title":"Eur J Paediatr Neurol"},{"key":"4601_CR14","doi-asserted-by":"publisher","first-page":"981","DOI":"10.3389\/fneur.2018.00981","volume":"9","author":"A D'Amore","year":"2018","unstructured":"D'Amore A, Tessa A, Casali C, Dotti MT, Filla A, Silvestri G, Antenora A, Astrea G, Barghigiani M, Battini R, Battisti C, Bruno I, Cereda C, Dato C, Di Iorio G, Donadio V, Felicori M, Fini N, Fiorillo C, Gallone S, Gemignani F, Gigli GL, Graziano C, Guerrini R, Gurrieri F, Kariminejad A, Lieto M, Marques LourenCo C, Malandrini A, Mandich P, Marcotulli C, Mari F, Massacesi L, Melone MAB, Mignarri A, Milone R, Musumeci O, Pegoraro E, Perna A, Petrucci A, Pini A, Pochiero F, Pons MR, Ricca I, Rossi S, Seri M, Stanzial F, Tinelli F, Toscano A, Valente M, Federico A, Rubegni A, Santorelli FM (2018) Next generation molecular diagnosis of hereditary spastic paraplegias: an Italian cross-sectional study. Front Neurol 9:981","journal-title":"Front Neurol"},{"key":"4601_CR15","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.neurol.2017.03.034","volume":"173","author":"L Parodi","year":"2017","unstructured":"Parodi L, Fenu S, Stevanin G, Durr A (2017) Hereditary spastic paraplegia: more than an upper motor neuron disease. Rev Neurol 173:352\u2013360","journal-title":"Rev Neurol"},{"key":"4601_CR16","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/j.expneurol.2014.06.011","volume":"261","author":"T Lo Giudice","year":"2014","unstructured":"Lo Giudice T, Lombardi F, Santorelli FM, Kawarai T, Orlacchio A (2014) Hereditary spastic paraplegia: clinical-genetic characteristics and evolving molecular mechanisms. Exp Neurol 261:518\u2013539","journal-title":"Exp Neurol"},{"key":"4601_CR17","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1097\/WCO.0000000000000585","volume":"31","author":"L Parodi","year":"2018","unstructured":"Parodi L, Coarelli G, Stevanin G, Brice A, Durr A (2018) Hereditary ataxias and paraparesias: clinical and genetic update. Curr Opin Neurol 31:462\u2013471","journal-title":"Curr Opin Neurol"},{"key":"4601_CR18","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.jocn.2013.04.020","volume":"21","author":"M Kai","year":"2014","unstructured":"Kai M, Yongjie L, Ping Z (2014) Long-term results of selective dorsal rhizotomy for hereditary spastic paraparesis. J Clin Neurosci 21:116\u2013120","journal-title":"J Clin Neurosci"},{"key":"4601_CR19","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1007\/s00381-016-3122-2","volume":"32","author":"J Sharma","year":"2016","unstructured":"Sharma J, Bonfield C, Steinbok P (2016) Selective dorsal rhizotomy for hereditary spastic paraparesis in children. Child\u2019s Nerv Syst 32:1489\u20131494","journal-title":"Child\u2019s Nerv Syst"},{"key":"4601_CR20","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.ejpn.2016.09.006","volume":"21","author":"AI Buizer","year":"2017","unstructured":"Buizer AI, van Schie PEM, Bolster EAM, van Ouwerkerk WJ, Strijers RL, van de Pol LA, Stadhouder A, Becher JG, Vermeulen RJ (2017) Effect of selective dorsal rhizotomy on daily care and comfort in non-walking children and adolescents with severe spasticity. Eur J Paediatr Neurol 21:350\u2013357","journal-title":"Eur J Paediatr Neurol"},{"key":"4601_CR21","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1136\/adc.2006.111559","volume":"92","author":"GF Cole","year":"2007","unstructured":"Cole GF, Farmer SE, Roberts A, Stewart C, Patrick JH (2007) Selective dorsal rhizotomy for children with cerebral palsy: the Oswestry experience. Arch Dis Child 92:781\u2013785","journal-title":"Arch Dis Child"},{"key":"4601_CR22","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1111\/j.1469-8749.2011.03912.x","volume":"53","author":"S Grunt","year":"2011","unstructured":"Grunt S, Becher JG, Vermeulen RJ (2011) Long-term outcome and adverse effects of selective dorsal rhizotomy in children with cerebral palsy: a systematic review. Dev Med Child Neurol 53:490\u2013498","journal-title":"Dev Med Child Neurol"},{"key":"4601_CR23","doi-asserted-by":"publisher","first-page":"557","DOI":"10.3171\/2011.2.PEDS10452","volume":"7","author":"PE van Schie","year":"2011","unstructured":"van Schie PE, Schothorst M, Dallmeijer AJ, Vermeulen RJ, van Ouwerkerk WJ, Strijers RL, Becher JG (2011) Short- and long-term effects of selective dorsal rhizotomy on gross motor function in ambulatory children with spastic diplegia. J Neurosurg Pediatr 7:557\u2013562","journal-title":"J Neurosurg Pediatr"},{"key":"4601_CR24","doi-asserted-by":"crossref","unstructured":"Rushna Raza* RL (2019) Approach to managing spasticity in heriditary spastic paraplegia 101136\/archdischild-2019-epa181","DOI":"10.1136\/archdischild-2019-epa.181"},{"key":"4601_CR25","doi-asserted-by":"publisher","first-page":"192","DOI":"10.3171\/2016.2.PEDS15527","volume":"18","author":"LR Grootveld","year":"2016","unstructured":"Grootveld LR, van Schie PE, Buizer AI, Jeroen Vermeulen R, van Ouwerkerk WJ, Strijers RL, Becher JJ (2016) Sudden falls as a persistent complication of selective dorsal rhizotomy surgery in children with bilateral spasticity: report of 3 cases. J Neurosurg Pediatr 18:192\u2013195","journal-title":"J Neurosurg Pediatr"},{"key":"4601_CR26","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1007\/s00381-016-3071-9","volume":"32","author":"NK Mazarakis","year":"2016","unstructured":"Mazarakis NK, Vloeberghs MH (2016) Spasticity secondary to Leigh syndrome managed with selective dorsal rhizotomy: a case report. Child\u2019s Nerv Syst 32:1745\u20131748","journal-title":"Child\u2019s Nerv Syst"},{"key":"4601_CR27","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/S2352-4642(19)30132-4","volume":"3","author":"AI Buizer","year":"2019","unstructured":"Buizer AI (2019) Selective dorsal rhizotomy in children with cerebral palsy. Lancet Child Adolesc Health 3:438\u2013439","journal-title":"Lancet Child Adolesc Health"},{"key":"4601_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jns.2012.03.025","volume":"318","author":"J Finsterer","year":"2012","unstructured":"Finsterer J, Loscher W, Quasthoff S, Wanschitz J, Auer-Grumbach M, Stevanin G (2012) Hereditary spastic paraplegias with autosomal dominant, recessive, X-linked, or maternal trait of inheritance. J Neurol Sci 318:1\u201318","journal-title":"J Neurol Sci"},{"key":"4601_CR29","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1111\/dmcn.12246","volume":"55","author":"I Novak","year":"2013","unstructured":"Novak I, McIntyre S, Morgan C, Campbell L, Dark L, Morton N, Stumbles E, Wilson SA, Goldsmith S (2013) A systematic review of interventions for children with cerebral palsy: state of the evidence. Dev Med Child Neurol 55:885\u2013910","journal-title":"Dev Med Child Neurol"},{"key":"4601_CR30","doi-asserted-by":"publisher","first-page":"901","DOI":"10.3389\/fneur.2019.00901","volume":"10","author":"E Pucks-Faes","year":"2019","unstructured":"Pucks-Faes E, Dobesberger J, Hitzenberger G, Matzak H, Mayr A, Fava E, Genelin E, Saltuari L (2019) Intrathecal baclofen in hereditary spastic paraparesis. Front Neurol 10:901","journal-title":"Front Neurol"},{"key":"4601_CR31","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.clineuro.2014.05.024","volume":"123","author":"K Margetis","year":"2014","unstructured":"Margetis K, Korfias S, Boutos N, Gatzonis S, Themistocleous M, Siatouni A, Dalivigka Z, Flaskas T, Stranjalis G, Boviatsis E, Sakas D (2014) Intrathecal baclofen therapy for the symptomatic treatment of hereditary spastic paraplegia. Clin Neurol Neurosurg 123:142\u2013145","journal-title":"Clin Neurol Neurosurg"},{"key":"4601_CR32","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/1471-2431-8-54","volume":"8","author":"E Nordmark","year":"2008","unstructured":"Nordmark E, Josenby AL, Lagergren J, Andersson G, Stromblad LG, Westbom L (2008) Long-term outcomes five years after selective dorsal rhizotomy. BMC Pediatr 8:54","journal-title":"BMC Pediatr"},{"key":"4601_CR33","volume-title":"GeneReviews((R))","author":"RW Orrell","year":"1993","unstructured":"Orrell RW (1993) ALS2-related disorders. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A (eds) GeneReviews((R)). University of Washington, Seattle University of Washington, Seattle GeneReviews is a registered trademark of the University of Washington, Seattle. All rights reserved., Seattle (WA)"},{"key":"4601_CR34","doi-asserted-by":"crossref","unstructured":"Jeffery SMT, Markia B, Pople IK, Aquilina K, Smith J, Mohamed AZ, Burchell A, Jenkins L, Walsh P, Clark N, Sacree J, Cramp M, Babiker MOE, Atherton WG, Clarke A, Edwards RJ (2019) Surgical outcomes of single-level bilateral selective dorsal rhizotomy for spastic diplegia in 150 consecutive patients. World Neurosurg","DOI":"10.1016\/j.wneu.2018.12.187"},{"key":"4601_CR35","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.neurol.2015.02.017","volume":"171","author":"S Klebe","year":"2015","unstructured":"Klebe S, Stevanin G, Depienne C (2015) Clinical and genetic heterogeneity in hereditary spastic paraplegias: from SPG1 to SPG72 and still counting. Rev Neurol 171:505\u2013530","journal-title":"Rev Neurol"},{"key":"4601_CR36","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.3389\/fneur.2018.01117","volume":"9","author":"FF da Graca","year":"2018","unstructured":"da Graca FF, de Rezende TJR, Vasconcellos LFR, Pedroso JL, Barsottini OGP, Franca MC Jr (2018) Neuroimaging in hereditary spastic paraplegias: current use and future perspectives. Front Neurol 9:1117","journal-title":"Front Neurol"},{"key":"4601_CR37","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s12311-016-0803-z","volume":"16","author":"PVS de Souza","year":"2017","unstructured":"de Souza PVS, de Rezende Pinto WBV, de Rezende Batistella GN, Bortholin T, Oliveira ASB (2017) Hereditary spastic paraplegia: clinical and genetic hallmarks. Cerebellum (London, England) 16:525\u2013551","journal-title":"Cerebellum (London, England)"},{"key":"4601_CR38","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000120302","volume":"13","author":"WJ Peacock","year":"1987","unstructured":"Peacock WJ, Arens LJ, Berman B (1987) Cerebral palsy spasticity. Selective posterior rhizotomy. Pediatr Neurosci 13:61\u201366","journal-title":"Pediatr Neurosci"}],"container-title":["Child's Nervous System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-020-04601-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00381-020-04601-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-020-04601-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T19:51:56Z","timestamp":1618516316000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00381-020-04601-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,16]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["4601"],"URL":"https:\/\/doi.org\/10.1007\/s00381-020-04601-x","relation":{},"ISSN":["0256-7040","1433-0350"],"issn-type":[{"value":"0256-7040","type":"print"},{"value":"1433-0350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,16]]},"assertion":[{"value":"9 January 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors do not have any conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}