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The sensor reservoir (SR) provides tICPM modality at a decent sampling rate as an integrated component of the CSF shunt system. The aim of this study is to perform tICPM during a defined protocol of maneuvers in an outpatient setting as feasibility study including either shunt-dependent patients or candidates for possible shunt therapy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A total of 17 patients received a SR and were investigated within a protocol of maneuver measurements involving different body postures (90\u00b0, 10\u00b0, 0\u00b0, and\u2009\u2212\u200910\u00b0), breathing patterns (hypo- and hyperventilation), and mild venous congestion (Valsalva, Jugular vein compression), while the latter two were performed in lying postures (10\u00b0 and 0\u00b0). The cohort included 11 shunted and 6 non-shunted (stand-alone-SR) patients. All measurements were evaluated using an ICP-analysis software (ICPicture, Miethke, Germany) looking at ICP\u00a0changes and amplitude (AMP) characteristics.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The shunted patient group consisted of 11 patients (median age: 15.8\u00a0years; range: 4\u201335.2\u00a0years) with either a\u00a0primary shunt\u00a0(n=9) and 2 patients received a shunt after stand-alone-SR tICPM. Six patients were enrolled with a stand-alone SR (median age 11.9\u00a0years, range 3.6\u201317.7\u00a0years). In the stand-alone SR group, maneuver related ICP and AMP\u00a0changes were more sensitive compared to shunted patients. Postural maneuvers caused significant ICP changes in all body positions in both groups. The highest ICP values were seen during Valsalva maneuver, provoked by the patients themselves. In the stand-alone group, significant higher ICP values during hyperventilation were observed compared to shunted individuals. In shunted patients, a significant correlation between ICP and AMP was observed only during hyperventilation maneuver, while this correlation was additionally\u00a0seen in\u00a0Valsalva and jugular vein compression in stand-alone patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>SR-related tICPM is helpful to objectify diagnostic evaluation in patients with CSF dynamic disturbances. The defined protocol did result in a wide range of ICP changes with promising potential for effective outpatient tICPM\u00a0investigation. Since the correlation of ICP and AMP was observed during mild venous congestion maneuvers it appears to be specifically\u00a0helpful for the evaluation of intracranial compliance. Further investigations of maneuver-related tICPM in a larger population, including variable pathologies, are needed to further establish the protocol in the clinical practice.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00381-022-05659-5","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T13:06:58Z","timestamp":1663074418000},"page":"185-195","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Maneuver protocol for outpatient telemetric intracranial pressure monitoring in hydrocephalus patients"],"prefix":"10.1007","volume":"39","author":[{"given":"Valentina","family":"Pennacchietti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schaumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4985-9847","authenticated-orcid":false,"given":"Ulrich-Wilhelm","family":"Thomale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,13]]},"reference":[{"key":"5659_CR1","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1080\/02688697.2020.1849544","volume":"35","author":"SI Korfias","year":"2021","unstructured":"Korfias SI, Banos S, Alexoudi A, Themistoklis K, Vlachakis E, Patrikelis P, Gatzonis S, Sakas DE (2021) Telemetric intracranial pressure monitoring: our experience with 22 patients investigated for intracranial hypertension. 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