{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:15:02Z","timestamp":1770815702688,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Childs Nerv Syst"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s00381-023-05926-z","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T05:02:56Z","timestamp":1679288576000},"page":"2221-2227","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Eosinophilic granuloma of the calvarium: is conservative management a valid option? Illustrative case and systematic review of the literature"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2150-1213","authenticated-orcid":false,"given":"Alberto","family":"Benato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulio","family":"Riva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3522-7267","authenticated-orcid":false,"given":"Fabio","family":"Raneri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"5926_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbo.2022.100454","volume":"36","author":"X Hu","year":"2022","unstructured":"Hu X, Buhtoiarov IN, Wang C, Sun Z, Zhu Q, Huang W, Yan W, Sun Y (2022) Langerhans cell histiocytosis: a population-based study of anatomical distribution and treatment patterns. J Bone Oncol 36:100454","journal-title":"J Bone Oncol"},{"issue":"5","key":"5926_CR2","doi-asserted-by":"publisher","first-page":"761","DOI":"10.5858\/2007-131-761-PSLITP","volume":"131","author":"SE Gibson","year":"2007","unstructured":"Gibson SE, Prayson RA (2007) Primary skull lesions in the pediatric population: a 25-year experience. Arch Pathol Lab Med 131(5):761\u2013766","journal-title":"Arch Pathol Lab Med"},{"issue":"4","key":"5926_CR3","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s00381-007-0523-2","volume":"24","author":"SH Yoon","year":"2008","unstructured":"Yoon SH, Park S-H (2008) A study of 77 cases of surgically excised scalp and skull masses in pediatric patients. Childs Nerv Syst 24(4):459\u2013465","journal-title":"Childs Nerv Syst"},{"issue":"3","key":"5926_CR4","doi-asserted-by":"publisher","first-page":"187","DOI":"10.3171\/PED\/2008\/1\/3\/187","volume":"1","author":"L Davidson","year":"2008","unstructured":"Davidson L, McComb JG, Bowen I, Krieger MD (2008) Craniospinal Langerhans cell histiocytosis in children: 30 years\u2019 experience at a single institution. J Neurosurg Pediatr 1(3):187\u2013195","journal-title":"J Neurosurg Pediatr"},{"issue":"1","key":"5926_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/2013.4.PEDS12482","volume":"12","author":"G De Angulo","year":"2013","unstructured":"De Angulo G, Nair S, Lee V, Khatib Z, Ragheb J, Sandberg DI (2013) Nonoperative management of solitary eosinophilic granulomas of the calvaria: Clinical article. J Neurosurg Pediatr 12(1):1\u20135","journal-title":"J Neurosurg Pediatr"},{"issue":"5","key":"5926_CR6","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1159\/000069828","volume":"38","author":"M Oliveira","year":"2003","unstructured":"Oliveira M, Steinbok P, Wu J, Heran N, Cochrane D (2003) Spontaneous resolution of calvarial eosinophilic granuloma in children. Pediatr Neurosurg 38(5):247\u2013252","journal-title":"Pediatr Neurosurg"},{"key":"5926_CR7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"issue":"26","key":"5926_CR8","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.1056\/NEJMc2203820","volume":"386","author":"P Steinbok","year":"2022","unstructured":"Steinbok P, Cheong A, Dix DB et al (2022) Nonoperative management of childhood calvarial Langerhans cell histiocytosis. N Engl J Med 386(26):2532\u20132534","journal-title":"N Engl J Med"},{"key":"5926_CR9","doi-asserted-by":"publisher","first-page":"466","DOI":"10.3389\/fped.2020.00466","volume":"8","author":"B Oh","year":"2020","unstructured":"Oh B, Lee S, Ke Y, Kimpo M, Yeoh A, Quah TC (2020) A \u201cWait-and-See\u201d approach to quiescent single-system Langerhans cell histiocytosis to spare children from chemotherapy. Front Pediatr 8:466","journal-title":"Front Pediatr"},{"issue":"4","key":"5926_CR10","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1177\/197140091002300412","volume":"23","author":"R Conforti","year":"2010","unstructured":"Conforti R, Porto A, Cirillo M, Sgambato A, Galderisi S, Cirillo S (2010) Spontaneous resolution of eosinophilic granuloma in a patient with a psychotic disorder. Neuroradiol J 23(4):437\u2013442","journal-title":"Neuroradiol J"},{"issue":"74","key":"5926_CR11","doi-asserted-by":"publisher","first-page":"265","DOI":"10.15557\/JoU.2018.0038","volume":"18","author":"F Vanhoenacker","year":"2018","unstructured":"Vanhoenacker F, Verlooy J, De Praeter M (2018) Spontaneous resolution of unifocal Langerhans cell histiocytosis of the skull: potential role of ultrasound in detection and imaging follow-up. J Ultrason 18(74):265\u2013270","journal-title":"J Ultrason"},{"key":"5926_CR12","doi-asserted-by":"crossref","unstructured":"Pires T, Duarte Santos C, Gonzalez Santos M, Luz L, Ferr\u00e3o A, Banza MJ (2021) Eosinophilic granuloma: a rare and often benign condition presenting as a lump on the head, which was easily treated. Eur J Case Rep Intern Med 11","DOI":"10.12890\/2021_002727"},{"issue":"5","key":"5926_CR13","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1177\/0194599815598969","volume":"153","author":"A Bezdjian","year":"2015","unstructured":"Bezdjian A, Alarfaj AA, Varma N, Daniel SJ (2015) Isolated Langerhans cell histiocytosis bone lesion in pediatric patients: systematic review and treatment algorithm. Otolaryngol Neck Surg 153(5):751\u2013757","journal-title":"Otolaryngol Neck Surg"},{"key":"5926_CR14","doi-asserted-by":"crossref","unstructured":"Senechal B, Elain G, Jeziorski E, Grondin V, Patey-Mariaud de Serre N, Jaubert F, Beldjord K, Lellouch A, Glorion C, Zerah M, Mary P, Barkaoui M, Emile JF, Boccon-Gibod L, Josset P, Debr\u00e9 M, Fischer A, Donadieu J, Geissmann F. Expansion of regulatory T cells in patients with Langerhans cell histiocytosis. PLoS Med. 2007 Aug;4(8):e253","DOI":"10.1371\/journal.pmed.0040253"},{"issue":"2","key":"5926_CR15","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1542\/peds.76.2.286","volume":"76","author":"RB Womer","year":"1985","unstructured":"Womer RB, Raney RB Jr, D\u2019Angio GJ (1985) Healing rates of treated and untreated bone lesions in histiocytosis X. Pediatrics 76(2):286\u2013288","journal-title":"Pediatrics"},{"issue":"7","key":"5926_CR16","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1007\/s00381-015-2676-8","volume":"31","author":"T Hollon","year":"2015","unstructured":"Hollon T, McKeever PE, Garton HJL, Maher CO (2015) Skull fracture mimicking eosinophilic granuloma. Childs Nerv Syst 31(7):1171\u20131174","journal-title":"Childs Nerv Syst"},{"issue":"7","key":"5926_CR17","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1007\/s00381-015-2687-5","volume":"31","author":"P Steinbok","year":"2015","unstructured":"Steinbok P (2015) Healing calvarial eosinophilic granuloma or healing skull fracture? Childs Nerv Syst 31(7):1175\u20131176","journal-title":"Childs Nerv Syst"},{"issue":"2","key":"5926_CR18","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1002\/pbc.24367","volume":"60","author":"R Haupt","year":"2013","unstructured":"Haupt R, Minkov M, Astigarraga I et al (2013) Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 years: Guidelines for Langerhans Cell Histiocytosis. Pediatr Blood Cancer 60(2):175\u2013184","journal-title":"Pediatr Blood Cancer"},{"issue":"5","key":"5926_CR19","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1007\/s13244-018-0643-0","volume":"9","author":"CK Gomez","year":"2018","unstructured":"Gomez CK, Schiffman SR, Bhatt AA (2018) Radiological review of skull lesions. Insights Imaging 9(5):857\u2013882","journal-title":"Insights Imaging"}],"container-title":["Child's Nervous System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-023-05926-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00381-023-05926-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-023-05926-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:04:05Z","timestamp":1744171445000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00381-023-05926-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,20]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["5926"],"URL":"https:\/\/doi.org\/10.1007\/s00381-023-05926-z","relation":{},"ISSN":["0256-7040","1433-0350"],"issn-type":[{"value":"0256-7040","type":"print"},{"value":"1433-0350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,20]]},"assertion":[{"value":"2 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No ethics approval was necessary for this study (case report and review of the literature). Written informed consent was obtained from the patient for the publication of this case report and accompanying images.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing financial or non-financial interests. There are no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}