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It is a rare, benign transformation of somatic tissue most commonly found in the sacrococcygeal region and may resemble an uncomplicated spina bifida on prenatal ultrasonography. In this case report, we describe a female newborn with an extremely rare mature cystic teratoma in the thoracolumbar region. She presented prenatally with a preliminary diagnosis of meningomyelocele, diastematomyelia, and Chiari II malformation and a possible teratoma. However, a mass containing solid glandular tissues and bony calcifications approximately 3\u2009\u00d7\u20094\u00a0cm in size was observed in the thoracolumbar region upon birth. During surgical resection, no nerve roots were found in the associated meningocele. The patient retained full lower body function postoperatively following surgical excision of the thecal sac and teratoma.<\/jats:p>","DOI":"10.1007\/s00381-024-06396-7","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T12:02:17Z","timestamp":1714392137000},"page":"2593-2598","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal diagnosis of meningomyelocele resolves as a mature cystic teratoma in the thoracolumbar region"],"prefix":"10.1007","volume":"40","author":[{"given":"Annie","family":"Chen-Carrington","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dean","family":"Leonard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Goodreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Rhodes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary W.","family":"Tye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,29]]},"reference":[{"issue":"7","key":"6396_CR1","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.jcma.2013.03.006","volume":"76","author":"Y-H Lu","year":"2013","unstructured":"Lu Y-H et al (2013) Unusual giant intraspinal teratoma in an infant. 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