{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:11:03Z","timestamp":1770819063033,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Childs Nerv Syst"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s00381-025-06910-5","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:10:42Z","timestamp":1757776242000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Wormian bones in simple sagittal synostosis: incidence and correlations"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3623-5744","authenticated-orcid":false,"given":"Pablo","family":"Miranda-Lloret","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estela","family":"Plaza-Ramirez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Pancucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Verdu-Ferrer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"Castello-Guarch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Menor-Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Antonio","family":"Simal-Julian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,13]]},"reference":[{"key":"6910_CR1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.22262","author":"SS Bellary","year":"2013","unstructured":"Bellary SS, Steinberg A, Mirzayan N, Shirak M, Tubbs RS, Cohen-Gadol AA et al (2013) Wormian bones: a review. Clin Anat. https:\/\/doi.org\/10.1002\/ca.22262","journal-title":"Clin Anat"},{"key":"6910_CR2","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1002\/ajpa.10304","volume":"123","author":"VD O\u2019Loughlin","year":"2004","unstructured":"O\u2019Loughlin VD (2004) Effects of different kinds of cranial deformation on the incidence of wormian bones. Am J Phys Anthropol 123:146\u2013155","journal-title":"Am J Phys Anthropol"},{"key":"6910_CR3","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32073","author":"PA Sanchez-Lara","year":"2007","unstructured":"Sanchez-Lara PA, Graham JM, Hing AV, Lee J, Cunningham M (2007) The morphogenesis of wormian bones: a study of craniosynostosis and purposeful cranial deformation. Am J Med Genet A. https:\/\/doi.org\/10.1002\/ajmg.a.32073","journal-title":"Am J Med Genet A"},{"key":"6910_CR4","doi-asserted-by":"crossref","unstructured":"MOSS ML (1959) The pathogenesis of premature cranial synostosis in man. Acta Anat (Basel) [Internet]. [cited 2025 May 18];37:351\u201370. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/14424622\/","DOI":"10.1159\/000141479"},{"key":"6910_CR5","doi-asserted-by":"crossref","unstructured":"Basnet LM, Shrestha S, Sapkota S (2019) Prevalence of wormian bones in dried adult human skulls: an osteo-morphometric study in Nepal. Anat Sci Int [Internet]. [cited 2025 May 17];94:101\u20139. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/30109567\/","DOI":"10.1007\/s12565-018-0454-x"},{"key":"6910_CR6","doi-asserted-by":"crossref","unstructured":"Li JH, Chen ZJ, Zhong WX, Yang H, Liu D, Li YK (2023) Anatomical characteristics and significance of the metopism and wormian bones in dry adult-Chinese skulls. Folia Morphologica (Poland) [Internet]. [cited 2025 May 18];82:166\u201375. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/35099043\/","DOI":"10.5603\/FM.a2022.0006"},{"key":"6910_CR7","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1097\/SCS.0000000000002370","volume":"27","author":"S Cirpan","year":"2016","unstructured":"Cirpan S, Aksu F, Mas N, Magden AO (2016) Coexistence of wormian bones with metopism, and vice versa, in adult skulls. J Craniofac Surg 27:493\u2013495","journal-title":"J Craniofac Surg"},{"key":"6910_CR8","doi-asserted-by":"crossref","unstructured":"Natsis K, Piagkou M, Lazaridis N, Anastasopoulos N, Nousios G, Piagkos G, et al (2019) Incidence, number and topography of wormian bones in Greek adult dry skulls. Folia Morphologica (Poland) [Internet]. [cited 2025 May 18];78:359\u201370. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/30155873\/","DOI":"10.5603\/FM.a2018.0078"},{"key":"6910_CR9","doi-asserted-by":"crossref","unstructured":"Pryles C V., Khan AJ (1979) Wormian bones. A marker of CNS abnormality? Am J Dis Child [Internet]. [cited 2025 May 17];133:380\u20132. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/433853\/","DOI":"10.1001\/archpedi.1979.02130040034007"},{"key":"6910_CR10","doi-asserted-by":"crossref","unstructured":"Marti B, Sirinelli D, Maurin L, Carpentier E (2013) Wormian bones in a general paediatric population. Diagn Interv Imaging [Internet]. [cited 2025 May 14];94:428\u201332. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/23352712\/","DOI":"10.1016\/j.diii.2013.01.001"},{"key":"6910_CR11","doi-asserted-by":"crossref","unstructured":"Albuhairan R, Alqahtani L, Aljebeli S, Shilash O Bin, Sultan A, Althuwaini A, et al (2025) Exploring pediatric sutural variations with three-dimensional computed tomography imaging: a retrospective study at a tertiary hospital. World Neurosurg 194.","DOI":"10.1016\/j.wneu.2024.123599"},{"key":"6910_CR12","doi-asserted-by":"crossref","unstructured":"Wu JK, Goodrich JT, Amadi CC, Miller T, Mulliken JB, Shanske AL (2011) Interparietal bone (Os Incae) in craniosynostosis. Am J Med Genet A [Internet]. [cited 2025 May 18];155:287\u201394. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/21271643\/","DOI":"10.1002\/ajmg.a.33800"},{"key":"6910_CR13","doi-asserted-by":"crossref","unstructured":"Dias MS, Samson T, Rizk EB, Governale LS, Richtsmeier JT, Aldana PR, et al (2020) Identifying the misshapen head: craniosynostosis and related disorders. Pediatrics [Internet]. [cited 2025 May 18];146. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/32868470\/","DOI":"10.1542\/peds.2020-015511"},{"key":"6910_CR14","doi-asserted-by":"crossref","unstructured":"Sgouros S, Hockley AD, Goldin JH, Wake MJC, Natarajan K (1999) Intracranial volume change in craniosynostosis. J Neurosurg [Internet]. [cited 2025 May 18];91:617\u201325. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/10507384\/","DOI":"10.3171\/jns.1999.91.4.0617"},{"key":"6910_CR15","doi-asserted-by":"crossref","unstructured":"Holland J, Rodrigues D, Mohan S, White N (2019) Intracranial volume (ICV) in isolated sagittal craniosynostosis: a retrospective case-matched-control study. Child\u2019s Nervous System [Internet]. [cited 2025 May 18] 35:509\u201316. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/30617577\/","DOI":"10.1007\/s00381-018-4018-0"},{"key":"6910_CR16","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1080\/0268869021000007560","volume":"16","author":"S Cerovac","year":"2002","unstructured":"Cerovac S, Neil-Dwyer JG, Rich P, Jones BM, Hayward RD (2002) Are routine preoperative CT scans necessary in the management of single suture craniosynostosis? Br J Neurosurg 16:348\u2013354","journal-title":"Br J Neurosurg"},{"key":"6910_CR17","doi-asserted-by":"crossref","unstructured":"Badve CA, Mallikarjunappa MK, Iyer RS, Ishak GE, Khanna PC (2013) Craniosynostosis: imaging review and primer on computed tomography. Pediatr Radiol p. 728\u201342.","DOI":"10.1007\/s00247-013-2673-6"},{"key":"6910_CR18","doi-asserted-by":"publisher","first-page":"672","DOI":"10.3174\/ajnr.A5063","volume":"38","author":"JC Montoya","year":"2017","unstructured":"Montoya JC, Eckel LJ, DeLone DR, Kotsenas AL, Diehn FE, Yu L et al (2017) Low-dose CT for craniosynostosis: preserving diagnostic benefit with substantial radiation dose reduction. AJNR Am J Neuroradiol 38:672\u2013677","journal-title":"AJNR Am J Neuroradiol"},{"key":"6910_CR19","unstructured":"Medina LS (2000) Three-dimensional CT maximum intensity projections of the calvaria: a new approach for diagnosis of craniosynostosis and fractures. AJNR Am J Neuroradiol [Internet]. 21:1951\u20134. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11110553"},{"key":"6910_CR20","unstructured":"Parker C (1905) Wormian Bones. 1905th ed. Robert Press, editor. Chicago."},{"key":"6910_CR21","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1007\/s00381-020-04844-8","volume":"37","author":"A Muroi","year":"2021","unstructured":"Muroi A, Enomoto T, Ihara S, Ishikawa E, Inagaki T, Matsumura A (2021) Developmental changes in the occipital cranial sutures of children less than 2 years of age. Childs Nerv Syst 37:567\u2013572","journal-title":"Childs Nerv Syst"},{"key":"6910_CR22","doi-asserted-by":"publisher","first-page":"667","DOI":"10.3171\/2016.5.PEDS14336","volume":"18","author":"J Pindrik","year":"2016","unstructured":"Pindrik J, Molenda J, Uribe-Cardenas R, Dorafshar AH, Ahn ES (2016) Normative ranges of anthropometric cranial indices and metopic suture closure during infancy. J Neurosurg Pediatr 18:667\u2013673","journal-title":"J Neurosurg Pediatr"},{"key":"6910_CR23","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s00381-018-3957-9","volume":"35","author":"SJ Teager","year":"2019","unstructured":"Teager SJ, Constantine S, Lottering N, Anderson PJ (2019) Physiologic closure time of the metopic suture in South Australian infants from 3D CT scans. Childs Nerv Syst 35:329\u2013335","journal-title":"Childs Nerv Syst"},{"key":"6910_CR24","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1007\/s00381-017-3628-2","volume":"34","author":"A Heli\u00f6vaara","year":"2018","unstructured":"Heli\u00f6vaara A, Leikola J, Koljonen V, Vuola P, Koivikko M (2018) Length of synostosis and segmented intracranial volume correlate with age in patients with non-syndromic sagittal synostosis. Childs Nerv Syst 34:511\u2013515","journal-title":"Childs Nerv Syst"},{"key":"6910_CR25","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3109\/2000656X.2013.793602","volume":"48","author":"Y Sakamoto","year":"2014","unstructured":"Sakamoto Y, Nakajima H, Tamada I, Miwa T, Kishi K, Yoshida K (2014) New pathogenesis and the classification in scaphocephaly. J Plast Surg Hand Surg 48:24\u201327","journal-title":"J Plast Surg Hand Surg"},{"key":"6910_CR26","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1097\/SCS.0000000000000478","volume":"25","author":"M Seruya","year":"2014","unstructured":"Seruya M, Tran J, Kumar S, Forrest CR, Chong DK (2014) Computed tomography-based morphometric analysis of extended strip craniectomy for sagittal synostosis. J Craniofac Surg 25:42\u201347","journal-title":"J Craniofac Surg"},{"key":"6910_CR27","doi-asserted-by":"publisher","DOI":"10.3171\/2023.7.PEDS23126","author":"V Matthijs","year":"2023","unstructured":"Matthijs V, Vandersteene J, Baert E, American Association of Neurological Surgeons (2023) Calvarial vault remodeling including pterional decompression for the treatment of nonsyndromic scaphocephaly patients: technical note and retrospective case series. J Neurosurg Pediatr. https:\/\/doi.org\/10.3171\/2023.7.PEDS23126","journal-title":"J Neurosurg Pediatr"},{"key":"6910_CR28","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1097\/SCS.0000000000010071","volume":"35","author":"MSIC Kurniawan","year":"2024","unstructured":"Kurniawan MSIC, Tio PAE, Abdel Alim T, Roshchupkin G, Dirven CMF, Pleumeekers MM et al (2024) 3D analysis of the cranial and facial shape in craniosynostosis patients: a systematic review. Journal of Craniofacial Surgery 35:813\u2013821","journal-title":"Journal of Craniofacial Surgery"},{"key":"6910_CR29","doi-asserted-by":"publisher","DOI":"10.3171\/2024.10.FOCUS24466","volume":"58","author":"JA Ramsey","year":"2025","unstructured":"Ramsey JA, Stevens PM, Coats B, Dixon TJ, Chaker SC, Bonfield CM et al (2025) Comprehensive craniometry for sagittal synostosis. Neurosurg Focus 58:E8","journal-title":"Neurosurg Focus"},{"key":"6910_CR30","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/j.wneu.2017.03.015","volume":"102","author":"I Barbero-Garc\u00eda","year":"2017","unstructured":"Barbero-Garc\u00eda I, Lerma JL, Marqu\u00e9s-Mateu \u00c1, Miranda P (2017) Low-cost smartphone-based photogrammetry for the analysis of cranial deformation in infants. World Neurosurg 102:545\u2013554","journal-title":"World Neurosurg"}],"container-title":["Child's Nervous System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-025-06910-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00381-025-06910-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00381-025-06910-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:17:04Z","timestamp":1770815824000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00381-025-06910-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,13]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["6910"],"URL":"https:\/\/doi.org\/10.1007\/s00381-025-06910-5","relation":{},"ISSN":["0256-7040","1433-0350"],"issn-type":[{"value":"0256-7040","type":"print"},{"value":"1433-0350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,13]]},"assertion":[{"value":"23 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was designed as an observational, retrospective analysis. Ethical approval was obtained from the institutional review board of the Neuroscience Area at Hospital Universitario La Fe (NCNCR25 0\u201310\/1).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}],"article-number":"280"}}