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Demographic, clinical, radiological, and surgical variables were recorded. Safety outcomes included complications, neurological deficits, length of stay, and 30-day readmission. Seizure outcomes were assessed by Engel classification and tumor response on follow-up MRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 27 children (mean age 11.6\u2009\u00b1\u20094.3\u00a0years) underwent LITT, including 18 treated for drug-resistant epilepsy and 9 for tumor indications. Same-session stereotactic biopsy was performed in 10 patients without biopsy-related complications or interference with ablation. Transient neurological deficits were observed in 5 patients and persistent deficits in 3. Hospital stay was 1\u20132\u00a0days in 23 patients, and no 30-day readmissions occurred. Seizure freedom (Engel class I) was achieved in 67% and 50% at 12 and 24\u00a0months, respectively. In tumor patients, clinical and MRI follow-up were available in all 9 patients, with one radiographic recurrence during follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this nationwide prospective cohort of 27 consecutively treated children, LITT demonstrated a favorable safety profile across epilepsy and tumor indications. Same-session stereotactic biopsy was feasible and safe, supporting LITT as a minimally invasive option in carefully selected pediatric patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00381-026-07438-y","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:25:38Z","timestamp":1788373538000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Laser interstitial thermal therapy in pediatric neurosurgery: a prospective nationwide study on indications, safety, and early outcomes"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3417-2444","authenticated-orcid":false,"given":"Silas Haahr","family":"Nielsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon","family":"Foss-Skiftesvik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torstein Ragnar","family":"Meling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid Marie","family":"Sehested","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina Engel","family":"H\u00f8i-Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Thude","family":"Callesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gorm","family":"von Oettingen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam Espe","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Skj\u00f8th-Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"issue":"6","key":"7438_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuchi.2025.101719","volume":"71","author":"O Aboubakr","year":"2025","unstructured":"Aboubakr O, Guida L, Dangouloff Ros V et al (2025) Laser interstitial thermal therapy (LITT) in pediatric neurosurgery: single center retrospective analysis of 41 consecutive procedures. 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