{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:47:55Z","timestamp":1789865275124,"version":"4.0.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2010,3,20]],"date-time":"2010-03-20T00:00:00Z","timestamp":1269043200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1007\/s00383-010-2586-5","type":"journal-article","created":{"date-parts":[[2010,3,19]],"date-time":"2010-03-19T08:13:17Z","timestamp":1268986397000},"page":"465-471","source":"Crossref","is-referenced-by-count":29,"title":["Genomics approach to the analysis of bacterial communities dynamics in Hirschsprung\u2019s disease-associated enterocolitis: a pilot study"],"prefix":"10.1007","volume":"26","author":[{"given":"C.","family":"De Filippo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pini-Prato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Mattioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Avanzini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Rapuzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Cavalieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Di Paola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Stefanini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Ceccherini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Mavilio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Lionetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Jasonni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,3,20]]},"reference":[{"key":"2586_CR1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00383-006-1845-y","volume":"23","author":"A Pini Prato","year":"2007","unstructured":"Pini Prato A, Avanzini S, Gentilino V et al (2007) Rectal suction biopsy in the workup of childhood chronic constipation: indications and diagnostic value. Pediatr Surg Int 23:117\u2013122","journal-title":"Pediatr Surg Int"},{"key":"2586_CR2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00383-007-2089-1","volume":"24","author":"A Pini Prato","year":"2008","unstructured":"Pini Prato A, Gentilino V, Giunta C et al (2008) Hirschsprung\u2019s disease: 13\u00a0years\u2019 experience in 112 patients from a single institution. Pediatr Surg Int 24:175\u2013182","journal-title":"Pediatr Surg Int"},{"key":"2586_CR3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jpedsurg.2004.09.052","volume":"40","author":"S Suita","year":"2005","unstructured":"Suita S, Taguchi T, Ieiri S et al (2005) Hirschsprung\u2019s disease in Japan: analysis of 3852 patients based on a nationwide survey in 30\u00a0years. J Pediatr Surg 40:197\u2013201 discussion 201\u2013202","journal-title":"J Pediatr Surg"},{"key":"2586_CR4","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/0022-3468(95)90334-8","volume":"30","author":"EA Elhalaby","year":"1995","unstructured":"Elhalaby EA, Teitelbaum DH, Coran AG et al (1995) Enterocolitis associated with Hirschsprung\u2019s disease: a clinical histopathological correlative study. J Pediatr Surg 30:1023\u20131026 discussion 1026\u20131027","journal-title":"J Pediatr Surg"},{"key":"2586_CR5","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s00383-005-1551-1","volume":"21","author":"F Murphy","year":"2005","unstructured":"Murphy F, Puri P (2005) Clostridium difficile-associated diarrhea in 200 Canadian children. Pediatr Surg Int 21:773\u2013779","journal-title":"Pediatr Surg Int"},{"key":"2586_CR6","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.jpedsurg.2007.12.057","volume":"43","author":"SW Moore","year":"2008","unstructured":"Moore SW, Sidler D, Zaahl MG (2008) The ITGB2 immunomodulatory gene (CD18), enterocolitis, and Hirschsprung\u2019s disease. J Pediatr Surg 43:1439\u20131444","journal-title":"J Pediatr Surg"},{"key":"2586_CR7","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1172\/JCI30587","volume":"117","author":"W Strober","year":"2007","unstructured":"Strober W, Fuss I, Mannon P (2007) The fundamental basis of inflammatory bowel disease. J Clin Invest 117:514\u2013521","journal-title":"J Clin Invest"},{"key":"2586_CR8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1053\/j.gastro.2007.05.017","volume":"133","author":"H Chinen","year":"2007","unstructured":"Chinen H, Matsuoka K, Sato T et al (2007) Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells. Gastroenterology 133:559\u2013573","journal-title":"Gastroenterology"},{"key":"2586_CR9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/ni.1681","volume":"10","author":"C Luci","year":"2009","unstructured":"Luci C, Reynders A, Ivanov II et al (2009) Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat Immunol 10:75\u201382","journal-title":"Nat Immunol"},{"key":"2586_CR10","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.immuni.2008.11.001","volume":"29","author":"N Satoh-Takayama","year":"2008","unstructured":"Satoh-Takayama N, Vosshenrich CA, Lesjean-Pottier S et al (2008) Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29:958\u2013970","journal-title":"Immunity"},{"key":"2586_CR11","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1155\/2005\/326296","volume":"19","author":"V Morinville","year":"2005","unstructured":"Morinville V, McDonald J (2005) Clostridium difficile-associated diarrhea in 200 Canadian children. Can J Gastroenterol 19:497\u2013501","journal-title":"Can J Gastroenterol"},{"key":"2586_CR12","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1099\/jmm.0.46045-0","volume":"55","author":"PP Chong","year":"2006","unstructured":"Chong PP, Chieng DC, Low LY et al (2006) Recurrent candidaemia in a neonate with Hirschsprung\u2019s disease: fluconazole resistance and genetic relatedness of eight Candida tropicalis isolates. J Med Microbiol 55:423\u2013428","journal-title":"J Med Microbiol"},{"key":"2586_CR13","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1126\/science.1110591","volume":"308","author":"PB Eckburg","year":"2005","unstructured":"Eckburg PB, Bik EM, Bernstein CN et al (2005) Diversity of the human intestinal microbial flora. Science 308:1635\u20131638","journal-title":"Science"},{"key":"2586_CR14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1023\/A:1000669317571","volume":"73","author":"G Muyzer","year":"1998","unstructured":"Muyzer G, Smalla K (1998) Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) in microbial ecology. Antonie Van Leeuwenhoek 73:127\u2013141","journal-title":"Antonie Van Leeuwenhoek"},{"key":"2586_CR15","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0168-6496(00)00080-5","volume":"34","author":"D Ch\u00e8neby","year":"2000","unstructured":"Ch\u00e8neby D, Philippot L, Hartmann A et al (2000) 16S rDNA analysis for characterization of denitrifying bacteria isolated from three agricultural soils. FEMS Microbiol Ecol 34:121\u2013128","journal-title":"FEMS Microbiol Ecol"},{"key":"2586_CR16","doi-asserted-by":"crossref","first-page":"5448","DOI":"10.1128\/AEM.66.12.5448-5456.2000","volume":"66","author":"JC Cho","year":"2000","unstructured":"Cho JC, Tiedje JM (2000) Biogeography and degree of endemicity of fluorescent Pseudomonas strains in soil. Appl Environ Microbiol 66:5448\u20135456","journal-title":"Appl Environ Microbiol"},{"key":"2586_CR17","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1038\/nprot.2006.142","volume":"1","author":"EG Zoetendal","year":"2006","unstructured":"Zoetendal EG, Heilig HG, Klaassens ES et al (2006) Isolation of DNA from bacterial samples of the human gastrointestinal tract. Nat Protoc 1:870\u2013873","journal-title":"Nat Protoc"},{"key":"2586_CR18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-3468(00)80031-7","volume":"35","author":"S Sancandi","year":"2000","unstructured":"Sancandi S, Ceccherini I, Costa M et al (2000) Population-based study of the incidence of RET mutations in Hirschsprung\u2019s disease patients. J Pediatr Surg 35:139\u2013142","journal-title":"J Pediatr Surg"},{"key":"2586_CR19","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1529-8817.2005.00196.x","volume":"70","author":"F Lantieri","year":"2006","unstructured":"Lantieri F, Griseri P, Puppo F et al (2006) Haplotypes of the human RET proto-oncogene associated with Hirschsprung disease in the Italian population derived from a single ancestral combination of alleles. Ann Hum Genet 70:12\u201326","journal-title":"Ann Hum Genet"},{"key":"2586_CR20","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/nature03467","volume":"434","author":"ES Emison","year":"2005","unstructured":"Emison ES, McCallion AS, Kashuk CS et al (2005) A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk. Nature 434:857\u2013863","journal-title":"Nature"},{"key":"2586_CR21","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1128\/JCM.36.9.2522-2529.1998","volume":"36","author":"JG Koeleman","year":"1998","unstructured":"Koeleman JG, Stoof J, Biesmans DJ et al (1998) Comparison of amplified ribosomal DNA restriction analysis, random amplified polymorphic DNA analysis, and amplified fragment length polymorphism fingerprinting for identification of Acinetobacter genomic species and typing of Acinetobacter baumannii. J Clin Microbiol 36:2522\u20132529","journal-title":"J Clin Microbiol"},{"issue":"8","key":"2586_CR22","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0923-2508(96)81061-8","volume":"146","author":"M Vaneechoutte","year":"1995","unstructured":"Vaneechoutte M, Riegel P, de Briel D et al (1995) Evaluation of the applicability of amplified rDNA-restriction analysis (ARDRA) to identification of species of the genus Corynebacterium. Res Microbiol 146(8):633\u2013641","journal-title":"Res Microbiol"},{"issue":"8","key":"2586_CR23","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1128\/JCM.31.8.2061-2065.1993","volume":"31","author":"M Vaneechoutte","year":"1993","unstructured":"Vaneechoutte M, De Beenhouwer H, Claeys G et al (1993) Identification of Mycobacterium species by using amplified ribosomal DNA restriction analysis. J Clin Microbiol 31(8):2061\u20132065","journal-title":"J Clin Microbiol"},{"key":"2586_CR24","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0025-5564(82)90027-X","volume":"59","author":"MD Hendy","year":"1982","unstructured":"Hendy MD, Penny D (1982) Branch and bound algorithms to determine minimal evolutionary trees. Math Biosci 59:277\u2013290","journal-title":"Math Biosci"},{"key":"2586_CR25","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nature05597","volume":"446","author":"H Veiga-Fernandes","year":"2007","unstructured":"Veiga-Fernandes H, Coles MC, Foster KE et al (2007) Tyrosine kinase receptor RET is a key regulator of Peyer\u2019s patch organogenesis. Nature 446:547\u2013551","journal-title":"Nature"},{"key":"2586_CR26","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1126\/science.1124234","volume":"312","author":"SR Gill","year":"2006","unstructured":"Gill SR, Pop M, Deboy RT et al (2006) Metagenomic analysis of the human distal gut microbiome. Science 312:1355\u20131359","journal-title":"Science"},{"key":"2586_CR27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/gut.53.1.1","volume":"53","author":"CP Tamboli","year":"2004","unstructured":"Tamboli CP, Neut C, Desreumaux P et al (2004) Dysbiosis in inflammatory bowel disease. Gut 53:1\u20134","journal-title":"Gut"},{"key":"2586_CR28","doi-asserted-by":"crossref","first-page":"e177","DOI":"10.1371\/journal.pbio.0050177","volume":"5","author":"C Palmer","year":"2007","unstructured":"Palmer C, Bik EM, Digiulio DB et al (2007) Development of the human infant intestinal microbiota. PLoS Biol 5:e177","journal-title":"PLoS Biol"},{"issue":"1","key":"2586_CR29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jpedsurg.2008.10.052","volume":"44","author":"AC Pastor","year":"2009","unstructured":"Pastor AC, Osman F, Teitelbaum DH, Caty MG, Langer JC (2009) Development of a standardized definition for Hirschsprung\u2019s-associated enterocolitis: a Delphi analysis. J Pediatr Surg 44(1):251\u2013256","journal-title":"J Pediatr Surg"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-010-2586-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00383-010-2586-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-010-2586-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T04:57:22Z","timestamp":1591160242000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00383-010-2586-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,20]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["2586"],"URL":"https:\/\/doi.org\/10.1007\/s00383-010-2586-5","relation":{},"ISSN":["0179-0358","1437-9813"],"issn-type":[{"value":"0179-0358","type":"print"},{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,20]]}}}