{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T10:45:58Z","timestamp":1781174758243,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1007\/s00383-018-4370-x","type":"journal-article","created":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T03:18:50Z","timestamp":1541042330000},"page":"9-14","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Abnormal Scn1b and Fxyd1 gene expression in the pulled-through ganglionic colon may influence functional outcome in patients with Hirschsprung\u2019s disease"],"prefix":"10.1007","volume":"35","author":[{"given":"Anne Marie","family":"O\u2019Donnell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Tomuschat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoum Fares","family":"Marayati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prem","family":"Puri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,11,1]]},"reference":[{"key":"4370_CR1","doi-asserted-by":"publisher","first-page":"351","DOI":"10.3389\/fphys.2018.00351","volume":"9","author":"N Edokobi","year":"2018","unstructured":"Edokobi N, Isom LL (2018) Voltage-gated sodium channel \u03b21\/\u03b21B subunits regulate cardiac physiology and pathophysiology. Front Physiol 9:351. \n                    https:\/\/doi.org\/10.3389\/fphys.2018.00351","journal-title":"Front Physiol"},{"issue":"5\u20136","key":"4370_CR2","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1007\/s10863-007-9105-y","volume":"39","author":"CM Franzin","year":"2007","unstructured":"Franzin CM, Gong XM, Teriete P, Marassi FM (2007) Structures of the FXYD regulatory proteins in lipid micelles and membranes. J Bioenerg Biomembr 39(5\u20136):379\u2013383. \n                    https:\/\/doi.org\/10.1007\/s10863-007-9105-y","journal-title":"J Bioenerg Biomembr"},{"issue":"8","key":"4370_CR3","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1043\/0003-9985(2002)126<0928:ADOICO>2.0.CO;2","volume":"126","author":"U Rolle","year":"2002","unstructured":"Rolle U, Piotrowska AP, Nemeth L, Puri P (2002) Altered distribution of interstitial cells of Cajal in Hirschsprung disease. Arch Pathol Lab Med 126(8):928\u2013933. \n                    https:\/\/doi.org\/10.1043\/0003-9985(2002)126%3C0928:ADOICO%3E2.0.CO;2","journal-title":"Arch Pathol Lab Med"},{"key":"4370_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.01.013","author":"D Coyle","year":"2015","unstructured":"Coyle D, O\u2019Donnell AM, Puri P (2015) Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung\u2019s disease. J Pediatr Surg. \n                    https:\/\/doi.org\/10.1016\/j.jpedsurg.2015.01.013","journal-title":"J Pediatr Surg"},{"issue":"12","key":"4370_CR5","doi-asserted-by":"publisher","first-page":"3335","DOI":"10.3748\/wjg.v22.i12.3335","volume":"22","author":"A O\u2019Donnell","year":"2016","unstructured":"O\u2019Donnell A, Coyle D, Puri P (2016) Deficiency of platelet-derived growth factor receptor-\u03b1-positive cells in Hirschsprung\u2019s disease colon. World J Gastroenterol 22(12):3335\u20133340","journal-title":"World J Gastroenterol"},{"key":"4370_CR6","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.ydbio.2004.03.015","volume":"270","author":"HM Young","year":"2004","unstructured":"Young HM, Bergner AJ, Anderson CR, Enomoto H, Milbrandt J, Newgreen DF, Whitington PM (2004) Dynamics of neural crest-derived cell migration in the embryonic mouse gut. Dev Biol 270:455\u2013473","journal-title":"Dev Biol"},{"issue":"18","key":"4370_CR7","doi-asserted-by":"publisher","first-page":"5635","DOI":"10.3748\/wjg.v21.i18.5635","volume":"21","author":"AM O\u2019Donnell","year":"2015","unstructured":"O\u2019Donnell AM, Coyle D, Puri P (2015) Decreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung\u2019s disease. World J Gastroenterol 21(18):5635\u20135640. \n                    https:\/\/doi.org\/10.3748\/wjg.v21.i18.5635","journal-title":"World J Gastroenterol"},{"issue":"4","key":"4370_CR8","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1053\/jpsu.2002.31610","volume":"37","author":"U Rolle","year":"2002","unstructured":"Rolle U, Nemeth L, Puri P (2002) Nitrergic innervation of the normal gut and in motility disorders of childhood. J Pediatr Surg 37(4):551\u2013567","journal-title":"J Pediatr Surg"},{"issue":"12","key":"4370_CR9","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1007\/s00383-006-1783-8","volume":"22","author":"M Menezes","year":"2006","unstructured":"Menezes M, Corbally M, Puri P (2006) Long-term results of bowel function after treatment for Hirschsprung\u2019s disease: a 29-year review. Pediatr Surg Int 22(12):987\u2013990. \n                    https:\/\/doi.org\/10.1007\/s00383-006-1783-8","journal-title":"Pediatr Surg Int"},{"issue":"9","key":"4370_CR10","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1016\/j.jpedsurg.2008.01.072","volume":"43","author":"M Menezes","year":"2008","unstructured":"Menezes M, Prato AP, Jasonni V, Puri P (2008) Long-term clinical outcome in patients with total colonic aganglionosis: a 31-year review. J Pediatr Surg 43(9):1696\u20131699. \n                    https:\/\/doi.org\/10.1016\/j.jpedsurg.2008.01.072","journal-title":"J Pediatr Surg"},{"issue":"8","key":"4370_CR11","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1007\/s00383-012-3117-3","volume":"28","author":"D Mc Laughlin","year":"2012","unstructured":"Mc Laughlin D, Friedmacher F, Puri P (2012) Total colonic aganglionosis: a systematic review and meta-analysis of long-term clinical outcome. Pediatr Surg Int 28(8):773\u2013779","journal-title":"Pediatr Surg Int"},{"key":"4370_CR12","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13839","author":"H Yao","year":"2018","unstructured":"Yao H, Fan J, Cheng YJ, Chen XM, Ji CC, Liu LJ, Zheng ZH, Wu SH (2018) SCN 1B\u03b2 mutations that affect their association with Kv4.3 underlie early repolarization syndrome. J Cell Mol Med. \n                    https:\/\/doi.org\/10.1111\/jcmm.13839","journal-title":"J Cell Mol Med"},{"issue":"3","key":"4370_CR13","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1161\/CIRCEP.108.779181","volume":"2","author":"H Watanabe","year":"2009","unstructured":"Watanabe H, Darbar D, Kaiser DW, Jiramongkolchai K, Chopra S, Donahue BS, Kannankeril PJ, Roden DM (2009) Mutations in sodium channel beta1- and beta2-subunits associated with atrial fibrillation. Circ Arrhythm Electrophysiol 2(3):268\u2013275. \n                    https:\/\/doi.org\/10.1161\/CIRCEP.108.779181","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"6","key":"4370_CR14","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/s10863-005-9476-x","volume":"37","author":"K Geering","year":"2005","unstructured":"Geering K (2005) Function of FXYD proteins, regulators of Na, K-ATPase. J Bioenerg Biomembr 37(6):387\u2013392. \n                    https:\/\/doi.org\/10.1007\/s10863-005-9476-x","journal-title":"J Bioenerg Biomembr"},{"issue":"1","key":"4370_CR15","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.aanat.2009.09.003","volume":"192","author":"RV Floyd","year":"2010","unstructured":"Floyd RV, Wray S, Martin-Vasallo P, Mobasheri A (2010) Differential cellular expression of FXYD1 (phospholemman) and FXYD2 (gamma subunit of Na, K-ATPase) in normal human tissues: a study using high density human tissue microarrays. Ann Anat 192(1):7\u201316. \n                    https:\/\/doi.org\/10.1016\/j.aanat.2009.09.003","journal-title":"Ann Anat"},{"issue":"4","key":"4370_CR16","doi-asserted-by":"publisher","first-page":"e0176031","DOI":"10.1371\/journal.pone.0176031","volume":"12","author":"MY Lee","year":"2017","unstructured":"Lee MY, Ha SE, Park C, Park PJ, Fuchs R, Wei L, Jorgensen BG, Redelman D, Ward SM, Sanders KM, Ro S (2017) Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures. PLoS One 12(4):e0176031. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0176031","journal-title":"PLoS One"},{"issue":"8","key":"4370_CR17","doi-asserted-by":"publisher","first-page":"e0182265","DOI":"10.1371\/journal.pone.0182265","volume":"12","author":"SE Ha","year":"2017","unstructured":"Ha SE, Lee MY, Kurahashi M, Wei L, Jorgensen BG, Park C, Park PJ, Redelman D, Sasse KC, Becker LS, Sanders KM, Ro S (2017) Transcriptome analysis of PDGFR\u03b1+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFR\u03b1+ cell hyperplasia. PLoS One 12(8):e0182265. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0182265","journal-title":"PLoS One"},{"issue":"2","key":"4370_CR18","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.ydbio.2016.04.001","volume":"417","author":"AJ Burns","year":"2016","unstructured":"Burns AJ, Goldstein AM, Newgreen DF, Stamp L, Schafer KH, Metzger M, Hotta R, Young HM, Andrews PW, Thapar N, Belkind-Gerson J, Bondurand N, Bornstein JC, Chan WY, Cheah K, Gershon MD, Heuckeroth RO, Hofstra RM, Just L, Kapur RP, King SK, McCann CJ, Nagy N, Ngan E, Obermayr F, Pachnis V, Pasricha PJ, Sham MH, Tam P, Vanden Berghe P (2016) White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies. Dev Biol 417(2):229\u2013251. \n                    https:\/\/doi.org\/10.1016\/j.ydbio.2016.04.001","journal-title":"Dev Biol"},{"key":"4370_CR19","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12993","author":"LA Stamp","year":"2017","unstructured":"Stamp LA, Young HM (2017) Recent advances in regenerative medicine to treat enteric neuropathies: use of human cells. Neurogastroenterol Motil. \n                    https:\/\/doi.org\/10.1111\/nmo.12993","journal-title":"Neurogastroenterol Motil"},{"key":"4370_CR20","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13369","author":"CJ McCann","year":"2018","unstructured":"McCann CJ, Thapar N (2018) Enteric neural stem cell therapies for enteric neuropathies. Neurogastroenterol Motil. \n                    https:\/\/doi.org\/10.1111\/nmo.13369","journal-title":"Neurogastroenterol Motil"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00383-018-4370-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-018-4370-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-018-4370-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T06:26:18Z","timestamp":1572589578000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00383-018-4370-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["4370"],"URL":"https:\/\/doi.org\/10.1007\/s00383-018-4370-x","relation":{},"ISSN":["0179-0358","1437-9813"],"issn-type":[{"value":"0179-0358","type":"print"},{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,1]]},"assertion":[{"value":"18 October 2018","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2018","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}