{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:53:20Z","timestamp":1790787200527,"version":"4.1.0"},"reference-count":62,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:00:00Z","timestamp":1634860800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:00:00Z","timestamp":1634860800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003196","name":"ministero della salute","doi-asserted-by":"publisher","award":["GR-2011-02347381"],"award-info":[{"award-number":["GR-2011-02347381"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s00383-021-05012-y","type":"journal-article","created":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T13:05:24Z","timestamp":1634907924000},"page":"83-98","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Pathways and microbiome modifications related to surgery and enterocolitis in Hirschsprung disease"],"prefix":"10.1007","volume":"38","author":[{"given":"Roberto","family":"Biassoni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddi","family":"Di Marco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Squillario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Ugolotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Mosconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Grazia","family":"Faticato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girolamo","family":"Mattioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Avanzini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3080-7481","authenticated-orcid":false,"given":"Alessio","family":"Pini Prato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,22]]},"reference":[{"key":"5012_CR1","first-page":"53","volume":"16","author":"Q Ma","year":"2019","unstructured":"Ma Q, Xing C, Long W, Wang HY, Liu Q, Wang RF (2019) Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis. J Neuro inflammation 16:53 (PubMed PMID: 30823925)","journal-title":"J Neuro inflammation"},{"key":"5012_CR2","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1038\/nrgastro.2015.69","volume":"12","author":"K Ray","year":"2015","unstructured":"Ray K (2015) Gut microbiota. Host-microbe interactions and the enteric nervous system: a new connection? Nat Rev Gastroentol Hepatol 12:311 (PubMed PMID: 25917439)","journal-title":"Nat Rev Gastroentol Hepatol"},{"key":"5012_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00383-014-3634-3","volume":"31","author":"SW Moore","year":"2015","unstructured":"Moore SW (2015) Total colonic aganglionosis and Hirschsprung\u2019s disease: a review. Pediatr Surg Int 31:1\u20139 (PubMed PMID: 25367097)","journal-title":"Pediatr Surg Int"},{"key":"5012_CR4","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1007\/s00383-010-2848-2","volume":"27","author":"A Pini Prato","year":"2011","unstructured":"Pini Prato A, Rossi V, Avanzini S, Mattioli G, Disma N, Jasonni V (2011) Hirschsprung\u2019s disease: what about mortality? Ped Surg Int 27:473\u2013478 (PubMed PMID: 21253751)","journal-title":"Ped Surg Int"},{"key":"5012_CR5","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1097\/MOP.0000000000000210","volume":"27","author":"A Gosain","year":"2015","unstructured":"Gosain A, Brinkman AS (2015) Hirschsprung\u2019s associated enterocolitis. Curr Opin Pediatr 27:364\u2013369 (PMID: 25944307)","journal-title":"Curr Opin Pediatr"},{"key":"5012_CR6","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s00383-010-2586-5","volume":"26","author":"C De Filippo","year":"2010","unstructured":"De Filippo C, Pini Prato A, Mattioli G, Avanzini S, Rapuzzi G, Cavalieri D et al (2010) Genomics approach to the analysis of bacterial communities dynamics in Hirschsprung\u2019s disease-associated enterocolitis: a pilot study. Ped Surg Int 26:465\u2013471 (PubMedPMID: 20306059)","journal-title":"Ped Surg Int"},{"key":"5012_CR7","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1097\/MPG.0000000000001999","volume":"67","author":"MI Neuvonen","year":"2018","unstructured":"Neuvonen MI, Korpela K, Kyrklund K, Salonen A, de Vos W, Rintala RJ et al (2018) IntestinalMicrobiota in HirschsprungDisease. J Pediatr Gastroenterol Nutr 67:594\u2013600 (PubMed PMID: 29652728)","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"5012_CR8","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s00383-007-2089-1","volume":"24","author":"A Pini Prato","year":"2008","unstructured":"Pini Prato A, Gentilino V, Giunta C, Avanzini S, Parodi S, Mattioli G et al (2008) Hirschsprung\u2019s disease: 13 years\u2019 experience in 112 patients from a single institution. Ped Surg Int 24:175\u2013182 (PubMed PMID: 18060412)","journal-title":"Ped Surg Int"},{"key":"5012_CR9","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1111\/j.1365-2982.2012.01937.x","volume":"24","author":"NL Ward","year":"2012","unstructured":"Ward NL, Pieretti A, Dowd SE, Cox SB, Goldstein AM (2012) Intestinal aganglionosis is associated with early and sustained disruption of the colonic microbiome. Neurogastroenterol Motil 24:874-e400 (PubMed PMID: 22626027)","journal-title":"Neurogastroenterol Motil"},{"key":"5012_CR10","doi-asserted-by":"publisher","first-page":"e0124172","DOI":"10.1371\/journal.pone.0124172","volume":"10","author":"PK Frykman","year":"2015","unstructured":"Frykman PK, Nordenskj\u00f6ld A, Kawaguchi A, Hui TT, Granstr\u00f6m AL, Cheng Z et al (2015) Characterization of bacterial and fungal microbiome in children with hirschsprung disease with and without a history of enterocolitis: a multicenter study. PLoS ONE 10:e0124172 (PubMed PMID: 25909773)","journal-title":"PLoS ONE"},{"key":"5012_CR11","doi-asserted-by":"publisher","first-page":"e0162079","DOI":"10.1371\/journal.pone.0162079","volume":"11","author":"Y Li","year":"2016","unstructured":"Li Y, Poroyko V, Yan Z, Pan L, Feng Y, Zhao P et al (2016) Characterization of Intestinal Microbiomes of Hirschsprung\u2019s Disease Patients with or without Enterocolitis Using Illumina-MiSeq High-Throughput Sequencing. PLoS ONE 11:e0162079 (PubMed PMID:27603009)","journal-title":"PLoS ONE"},{"key":"5012_CR12","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3389\/fped.2019.00326","volume":"7","author":"A Pini Prato","year":"2019","unstructured":"Pini Prato A, Bartow-McKenney C, Hudspeth K, Mosconi M, Rossi V, Avanzini S et al (2019) A. Metagenomics Study on Hirschsprung\u2019s Disease Associated Enterocolitis: Biodiversity and Gut Microbial Homeostasis Depend on Resection Length and Patient\u2019s Clinical History. Front Pediatr 7:326 (PubMed PMID: 31448249)","journal-title":"Front Pediatr"},{"key":"5012_CR13","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1080\/19490976.2020.1711685","volume":"11","author":"W Tang","year":"2020","unstructured":"Tang W, Su Y, Yuan C, Zhang Y, Zhou L, Peng L, Wang P, Chen G, Li Y, Li H, Zhi Z, Chang H, Hang B, Mao JH, Snijders AM, Xia Y (2020) Prospective study reveals a microbiome signature that predicts the occurrence of post-operative enterocolitis in Hirschsprung disease (HSCR) patients. Gut Microbes 11:842\u2013854 (PMID: 31944159)","journal-title":"Gut Microbes"},{"key":"5012_CR14","doi-asserted-by":"publisher","first-page":"30","DOI":"10.5223\/pghn.2021.24.1.30","volume":"24","author":"RA Arbizu","year":"2021","unstructured":"Arbizu RA, Collins D, Wilson RC, Alekseyenko AV (2021) Evidence for differentiation of colon tissue microbiota in patients with and without postoperative hirschsprung\u2019s associated enterocolitis: a pilot study. Pediatr Gastroenterol Hepatol Nutr 24:30\u201337 (PMID: 33505891)","journal-title":"Pediatr Gastroenterol Hepatol Nutr"},{"key":"5012_CR15","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1038\/s41586-018-0617-x","volume":"562","author":"CJ Stewart","year":"2018","unstructured":"Stewart CJ, Ajami NJ, O\u2019Brien JL, Hutchinson DS, Smith DP, Wong MC et al (2018) Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature 562:583\u2013588 (PubMed PMID: 30356187)","journal-title":"Nature"},{"key":"5012_CR16","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3389\/fimmu.2014.00427","volume":"5","author":"MC Arrieta","year":"2014","unstructured":"Arrieta MC, Stiemsma LT, Amenyogbe N, Brown EM, Finlay B (2014) The intestinal microbiome in early life: health and disease. Front Immunol 5:427 (PubMed PMID: 25250028)","journal-title":"Front Immunol"},{"key":"5012_CR17","first-page":"251","volume":"44","author":"AC Pastor","year":"2009","unstructured":"Pastor AC, Osman F, Teitelbaum DH, Caty MG, Langer JC (2009) Development of a standardized definition for Hirschsprung\u2019s-associated enterocolitis: a Delphi analysis. J PediatrSurg 44:251\u2013256 (PubMed PMID: 19159752)","journal-title":"J PediatrSurg"},{"key":"5012_CR18","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/0022-3468(95)90615-0","volume":"30","author":"EA Elhalaby","year":"1995","unstructured":"Elhalaby EA, Coran AG, Blane CE, Hirschl RB, Teitelbaum DH (1995) Enterocolitis associated with Hirschsprung\u2019s disease: a clinical-radiological characterization based on 168 patients. J Pediatr Surg 30:76\u201383 (PubMed PMID: 7722836)","journal-title":"J Pediatr Surg"},{"key":"5012_CR19","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1186\/1471-2180-9-123","volume":"9","author":"D Mariat","year":"2009","unstructured":"Mariat D, Firmesse O, Levenez F, Guimar\u0103es V, Sokol H, Dor\u00e9 J, Corthier G, Furet JP (2009) TheFirmicutes\/Bacteroidetes ratio of the human microbiota changes with age. BMC Microbiol 9:123 (PMID: 19508720)","journal-title":"BMC Microbiol"},{"key":"5012_CR20","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/978-1-0716-0239-3_17","volume":"2104","author":"J Chong","year":"2020","unstructured":"Chong J, Xia J (2020) Using MetaboAnalyst 4.0 for metabolomics data analysis, interpretation, and integration with other omics data. Methods Mol Biol 2104:337\u2013360 (PubMedPMID: 31953825)","journal-title":"Methods Mol Biol"},{"key":"5012_CR21","doi-asserted-by":"publisher","first-page":"W180","DOI":"10.1093\/nar\/gkx295","volume":"45","author":"A Dhariwal","year":"2017","unstructured":"Dhariwal A, Chong J, Habib S, King IL, Agellon LB, Xia J (2017) MicrobiomeAnalyst: a web-based tool for comprehensive statistical, visual and meta-analysis of microbiome data. Nucleic Acids Res 45:W180\u2013W188 (PubMed PMID: 28449106)","journal-title":"Nucleic Acids Res"},{"key":"5012_CR22","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1186\/1471-2105-9-559","volume":"9","author":"P Langfelder","year":"2008","unstructured":"Langfelder P, Horvath S (2008) WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 9:559 (PubMed PMID: 19114008)","journal-title":"BMC Bioinformatics"},{"issue":"1","key":"5012_CR23","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Y Benjamini","year":"1995","unstructured":"Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Statist Soc Ser B 57(1):289\u2013300","journal-title":"J Roy Statist Soc Ser B"},{"key":"5012_CR24","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/978-1-4939-8728-3_11","volume":"1849","author":"GM Douglas","year":"2018","unstructured":"Douglas GM, Beiko RG, Langille MGI (2018) Predicting the functional potential of the microbiome from marker genes using PICRUSt. Methods Mol Biol 1849:169\u2013177 (PubMed PMID: 30298254)","journal-title":"Methods Mol Biol"},{"key":"5012_CR25","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","volume":"28","author":"M Kanehisa","year":"2000","unstructured":"Kanehisa M, Goto S (2000) Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28:27\u201330 (PubMed PMID: 10592173)","journal-title":"Nucleic Acids Res"},{"key":"5012_CR26","doi-asserted-by":"publisher","first-page":"E1715","DOI":"10.3390\/microorganisms8111715","volume":"8","author":"S Stojanov","year":"2020","unstructured":"Stojanov S, Berlec A, \u0160trukelj B (2020) The Influence of Probiotics on the Firmicutes\/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease. Microorganisms 8:E1715 (PubMedPMID: 33139627)","journal-title":"Microorganisms"},{"key":"5012_CR27","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3390\/microorganisms6030075","volume":"6","author":"SY Geerlings","year":"2018","unstructured":"Geerlings SY, Kostopoulos I, de VosWM BC (2018) Akkermansiamuciniphila in the Human Gastrointestinal Tract: When, Where, and How? Microorganisms 6:75 (PubMed PMID: 30041463)","journal-title":"Microorganisms"},{"key":"5012_CR28","doi-asserted-by":"publisher","first-page":"1707610","DOI":"10.1080\/19490976.2019.1707610","volume":"12","author":"GM Agudelo-Ochoa","year":"2020","unstructured":"Agudelo-Ochoa GM, Vald\u00e9s-Duque BE, Giraldo-Giraldo NA, Jaillier-Ram\u00edrez AM, Giraldo-Villa A, Acevedo-Casta\u00f1o I et al (2020) Gut microbiota profiles in critically ill patients, potential biomarkers and risk variables for sepsis. Gut Microbes 12:1707610 (PubMed PMID: 31924126)","journal-title":"Gut Microbes"},{"key":"5012_CR29","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/j.1365-2958.2008.06126.x","volume":"68","author":"P Shah","year":"2008","unstructured":"Shah P, Swiatlo E (2008) A multifaceted role for polyamines in bacterial pathogens. Mol Microbiol 68:4\u201316 (PubMed PMID: 18405343)","journal-title":"Mol Microbiol"},{"key":"5012_CR30","doi-asserted-by":"publisher","first-page":"27094","DOI":"10.1016\/S0021-9258(19)74222-7","volume":"268","author":"B Stolz","year":"1993","unstructured":"Stolz B, Huber M, Markovic\u2019-Housley Z, Erni B (1993) The Mannose Transporter of Escherichia coli. Structure and Function of the IIABMan Subunit. J Biol Chem 268:27094\u201327099 (PubMed PMID: 8262947)","journal-title":"J Biol Chem"},{"key":"5012_CR31","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1515\/bchm3.1994.375.8.551","volume":"375","author":"E Rhiel","year":"1994","unstructured":"Rhiel E, Flukiger K, Wehrli C, ErniB, (1994) The mannose transporter of Escherichia coli K12: oligomeric structure, and function of two conserved cysteines. Biol Chem Hoppe Seyler 375:551\u2013559 (PubMed PMID: 7811395)","journal-title":"Biol Chem Hoppe Seyler"},{"key":"5012_CR32","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1128\/JB.184.2.363-369.2002","volume":"184","author":"MC KneidingerB","year":"2002","unstructured":"KneidingerB MC, Graninger M, Zamyatina A, McArthur F, Kosma P et al (2002) Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli. J Bacteriol 184:363\u2013369 (PubMed PMID: 11751812)","journal-title":"J Bacteriol"},{"key":"5012_CR33","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/j.cell.2008.03.033","volume":"133","author":"H Remaut","year":"2008","unstructured":"Remaut H, Tang C, Henderson NS, Pinkner JS, Wang T, Hultgren SJ et al (2008) Fiber formation across the bacterial outer membrane by the chaperone\/usher pathway. Cell 133:640\u2013652 (PubMed PMID: 18485872)","journal-title":"Cell"},{"key":"5012_CR34","first-page":"551","volume":"71","author":"SP Nuccio","year":"2007","unstructured":"Nuccio SP, B\u00e4umler AJ (2007) Evolution of the chaperone\/usher assembly pathway: fimbrial classification goes Greek. MicrobiolMolBiol Rev 71:551\u2013575 (PubMed PMID: 18063717)","journal-title":"MicrobiolMolBiol Rev"},{"key":"5012_CR35","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1111\/j.1365-2958.1993.tb01589.x","volume":"8","author":"PJ Reeves","year":"1993","unstructured":"Reeves PJ, Whitcombe D, Wharam S, Gibson M, Allison G, Bunce N et al (1993) Molecular cloning and characterization of 13 out genes from Erwiniacarotovora subspecies carotovora: genes encoding members of a general secretion pathway (GSP) widespread in gram-negative bacteria. Mol Microbiol 8:443\u2013456 (PubMed PMID: 8326859)","journal-title":"Mol Microbiol"},{"key":"5012_CR36","first-page":"135","volume":"1523","author":"M Brandenberger","year":"2000","unstructured":"Brandenberger M, Tschierske M, Giachino P, Wada A, Berger-B\u00e4chi B (2000) Inactivation of a novel three-cistronic operon tcaR-tcaA-tcaB increases teicoplanin resistance in Staphylococcus aureus. BiochimBiophysActa 1523:135\u2013139 (PubMed PMID: 11042376)","journal-title":"BiochimBiophysActa"},{"key":"5012_CR37","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1128\/AAC.42.1.88","volume":"42","author":"G Vedantam","year":"1998","unstructured":"Vedantam G, Guay GG, Austria NE, Doktor SZ, Nichols BP (1998) Characterization of mutations contributing to sulfathiazole resistance in Escherichia coli. Antimicrob Agents Chemother 42:88\u201393 (PubMed PMID: 9449266)","journal-title":"Antimicrob Agents Chemother"},{"key":"5012_CR38","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1111\/j.1432-1033.1985.tb08768.x","volume":"147","author":"JK Broome-Smith","year":"1985","unstructured":"Broome-Smith JK, Edelman A, Yousif S, Spratt BG (1985) The Nucleotide Sequences of the ponA and ponB Genes Encoding Penicillin-Binding Protein 1A and 1B of Escherichia Coli K12. Eur J Biochem 147:437\u2013446 (PubMed PMID: 3882429)","journal-title":"Eur J Biochem"},{"key":"5012_CR39","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1152\/physrev.00045.2009","volume":"90","author":"I Sekirov","year":"2010","unstructured":"Sekirov I, Russell SL, Antunes LC, Finlay BB (2010) Gut microbiota in health and disease. Physiol Rev 90:859\u2013904 (PMID: 20664075)","journal-title":"Physiol Rev"},{"key":"5012_CR40","doi-asserted-by":"publisher","first-page":"e177","DOI":"10.1371\/journal.pbio.0050177","volume":"5","author":"C Palmer","year":"2007","unstructured":"Palmer C, Bik EM, Di Giulio DB, Relman DA, Brown PO (2007) Development of the human infant intestinal microbiota. PLoS Biol 5:e177 (PubMed PMID: 17594176)","journal-title":"PLoS Biol"},{"key":"5012_CR41","doi-asserted-by":"crossref","unstructured":"Ludwig W, Schleifer KH, Whitman WB (2015) Enterococcaceae fam. nov.\u00a0John Wiley & Sons, Inc., in association with Bergey's Manual Trust","DOI":"10.1002\/9781118960608.fbm00125"},{"key":"5012_CR42","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1016\/j.jpeds.2014.09.041","volume":"166","author":"S Arboleya","year":"2015","unstructured":"Arboleya S, S\u00e1nchez B, Milani C, Duranti S, Sol\u00eds G, Fern\u00e1ndez N et al (2015) Intestinal microbiota development in preterm neonates and effect of perinatal antibiotics. J Pediatr 166:538\u2013544 (PubMed PMID: 25444008)","journal-title":"J Pediatr"},{"key":"5012_CR43","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1111\/j.1574-695X.2009.00553.x","volume":"56","author":"S Tanaka","year":"2009","unstructured":"Tanaka S, Kobayashi T, Songjinda P, Tateyama A, Tsubouchi M, KiyoharaC, et al (2009) Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota. FEMS Immunol Med Microbiol 56:80\u201387 (PubMed PMID: 19385995)","journal-title":"FEMS Immunol Med Microbiol"},{"key":"5012_CR44","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1097\/ACO.0000000000000734","volume":"32","author":"E Lukovic","year":"2019","unstructured":"Lukovic E, Moitra VK, Freedberg DE (2019) The microbiome: implications for perioperative and critical care. Curr Opin Anaesthesiol 32:412\u2013420 (PMID: 30925514)","journal-title":"Curr Opin Anaesthesiol"},{"key":"5012_CR45","doi-asserted-by":"publisher","first-page":"20340","DOI":"10.1038\/s41598-020-77285-7","volume":"10","author":"H Nalluri","year":"2020","unstructured":"Nalluri H, Kizy S, Ewing K, Luthra G, Leslie DB, Bernlohr DA, Sadowsky MJ, Ikramuddin S, Khoruts A, Staley C, Jahansouz C (2020) Peri-operative antibiotics acutely and significantly impact intestinal microbiota following bariatric surgery. Sci Rep 10:20340 (PMID: 33230230)","journal-title":"Sci Rep"},{"key":"5012_CR46","doi-asserted-by":"publisher","first-page":"e14","DOI":"10.1002\/bjs.10405","volume":"104","author":"JC Alverdy","year":"2017","unstructured":"Alverdy JC, Hyoju SK, Weigerinck M, Gilbert JA (2017) The gut microbiome and the mechanism of surgical infection. Br J Surg 104:e14\u2013e23 (PMID: 28121030)","journal-title":"Br J Surg"},{"key":"5012_CR47","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.chom.2007.06.010","volume":"2","author":"C Lupp","year":"2007","unstructured":"Lupp C, Robertson ML, Wickham ME, Sekirov I, Champion OL, Gaynor EC et al (2007) Host mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe 2:119\u2013129 (PubMed PMID: 18005726)","journal-title":"Cell Host Microbe"},{"key":"5012_CR48","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1007\/s00018-008-8477-4","volume":"66","author":"T Profta","year":"2009","unstructured":"Profta T, Baker EN (2009) Pili in Gram-negative and Gram-positive bacteria \u2013 structure, assembly and their role in disease. Cell Mol Life Sci 66:613\u2013635 (PubMed PMID: 18953686)","journal-title":"Cell Mol Life Sci"},{"key":"5012_CR49","doi-asserted-by":"publisher","first-page":"e0005586","DOI":"10.1371\/journal.pntd.0005586","volume":"11","author":"A Sheikh","year":"2017","unstructured":"Sheikh A, Rashu R, Begum YA, Kuhlman FM, Ciorba MA, Hultgren SJ, Qadri F, Fleckenstein JM (2017) Highly conserved type 1 pili promote enterotoxigenic E coli pathogen-host interactions. PLoS Negl Trop Dis 11:e0005586 (PubMedPMID: 28531220)","journal-title":"PLoS Negl Trop Dis"},{"key":"5012_CR50","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1046\/j.1365-2958.2003.03835.x","volume":"51","author":"G Sturgill","year":"2004","unstructured":"Sturgill G, Rather PN (2004) Evidence that putrescine acts as an extracellular signal required for swarming in Proteus mirabilis. Mol Microbiol 51:437\u2013446 (PubMed PMID: 14756784)","journal-title":"Mol Microbiol"},{"key":"5012_CR51","doi-asserted-by":"publisher","first-page":"2261","DOI":"10.1073\/pnas.2627990100","volume":"100","author":"MK Chattopadhyay","year":"2003","unstructured":"Chattopadhyay MK, Tabor CW, Tabor H (2003) Polyamines protect Escherichia coli cells from the toxic effect of oxygen. Proc Natl Acad Sci USA 100:2261\u20132265 (PubMed PMID: 12591940)","journal-title":"Proc Natl Acad Sci USA"},{"key":"5012_CR52","first-page":"609","volume":"93","author":"ER Frawley","year":"2014","unstructured":"Frawley ER, Fang FC (2014) The ins and outs of bacterial iron metabolism. MolMicrobiol 93:609\u2013616 (PubMed PMID: 25040830)","journal-title":"MolMicrobiol"},{"key":"5012_CR53","first-page":"137","volume":"6","author":"CM Litwin","year":"1993","unstructured":"Litwin CM, Calderwood SB (1993) Role of iron in regulation of virulence genes. ClinMicrobiol Rev 6:137\u2013149 (PubMed PMID: 8472246)","journal-title":"ClinMicrobiol Rev"},{"key":"5012_CR54","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1002\/ijc.31559","volume":"143","author":"GY Koh","year":"2018","unstructured":"Koh GY, Kane A, Lee K, Xu Q, Wu X, Roper J et al (2018) Parabacteroidesdistasonisattenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. Int J Cancer 143:1797\u20131805 (PubMed PMID: 29696632)","journal-title":"Int J Cancer"},{"key":"5012_CR55","doi-asserted-by":"publisher","first-page":"906","DOI":"10.3389\/fimmu.2020.00906","volume":"11","author":"BJ Parker","year":"2020","unstructured":"Parker BJ, Wearsch PA, Veloo ACM, Rodriguez-Palacios A (2020) The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health. Front Immunol 11:906 (PubMed PMID: 32582143)","journal-title":"Front Immunol"},{"key":"5012_CR56","doi-asserted-by":"publisher","first-page":"9523","DOI":"10.1038\/s41598-017-10034-5","volume":"7","author":"ML Santoru","year":"2017","unstructured":"Santoru ML, Piras C, Murgia A, Palmas V, Camboni T, Liggi S et al (2017) Cross sectional evaluation of the gut-microbiomemetabolome axis in an Italian cohort of IBD patients. Sci Rep 7:9523 (PubMed PMID: 28842640)","journal-title":"Sci Rep"},{"key":"5012_CR57","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1128\/JB.01354-13","volume":"196","author":"CA Portela","year":"2014","unstructured":"Portela CA, Smart KF, Tumanov S, Cook GM, Villas-B\u00f4as SG (2014) Global metabolic response of Enterococcus faecalis to oxygen. J Bacteriol 196:2012\u20132022 (PubMed PMID: 24659768)","journal-title":"J Bacteriol"},{"key":"5012_CR58","doi-asserted-by":"publisher","first-page":"e97523","DOI":"10.1371\/journal.pone.0097523","volume":"9","author":"S Wang","year":"2014","unstructured":"Wang S, Hibberd ML, Pettersson S, Lee YK (2014) Enterococcus faecalis from Healthy Infants Modulates Inflammation through MAPK Signaling Pathways. PLoS ONE 9:e97523 (PubMed PMID: 24830946)","journal-title":"PLoS ONE"},{"key":"5012_CR59","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3389\/fsurg.2018.00030","volume":"5","author":"Z Cheng","year":"2018","unstructured":"Cheng Z, Zhao L, Dhall D, Ruegger PM, Borneman J, Frykman PF (2018) Bacterial Microbiome Dynamics in Post Pull-Through Hirschsprung-Associated Enterocolitis (HAEC): An Experimental Study Employing the Endothelin Receptor B-Null Mouse Model. Front Surg 5:30 (PubMed PMID: 29682507)","journal-title":"Front Surg"},{"key":"5012_CR60","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.3390\/jcm8101656","volume":"8","author":"I Kushkevych","year":"2019","unstructured":"Kushkevych I, Le\u0161\u010danov\u00e1 O, Dordevi\u0107 D, Jan\u010d\u00edkov\u00e1 S, Ho\u0161ek J, V\u00edt\u011bzov\u00e1 M et al (2019) The Sulfate-Reducing Microbial Communities and Meta-Analysis of Their Occurrence during Diseases of Small-Large Intestine Axis. J Clin Med 8:1656 (PubMedPMID: 31614543)","journal-title":"J Clin Med"},{"key":"5012_CR61","doi-asserted-by":"publisher","first-page":"2802","DOI":"10.1038\/s41467-018-05249-7","volume":"9","author":"JM Natividad","year":"2018","unstructured":"Natividad JM, Lamas B, Pham HP, Michel ML, Rainteau D, Bridonneau C et al (2018) Bilophilawadsworthiaaggravates high fat diet induced metabolicdysfunctions in mice. Nat Commun 9:2802 (PubMed PMID: 30022049)","journal-title":"Nat Commun"},{"key":"5012_CR62","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.bbagen.2005.12.008","volume":"1760","author":"N Sharon","year":"2006","unstructured":"Sharon N (2006) Carbohydrates as future anti-adhesion drugs for infectious diseases. Biochimica et BiophysicaActa 1760:527\u2013537 (PubMed PMID: 16564136)","journal-title":"Biochimica et BiophysicaActa"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-021-05012-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00383-021-05012-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-021-05012-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T14:48:47Z","timestamp":1725979727000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00383-021-05012-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,22]]},"references-count":62,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["5012"],"URL":"https:\/\/doi.org\/10.1007\/s00383-021-05012-y","relation":{},"ISSN":["0179-0358","1437-9813"],"issn-type":[{"value":"0179-0358","type":"print"},{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,22]]},"assertion":[{"value":"11 September 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Informed consent was obtained from all individual participants or their family included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}