{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:23:40Z","timestamp":1790011420991,"version":"4.0.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T00:00:00Z","timestamp":1673827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T00:00:00Z","timestamp":1673827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>ECMO is an escalation treatment for hypoxic respiratory failure in patients with CDH. Open repair has been advocated after ECMO indicating that physiological changes associated to thoracoscopic repair were not well tolerated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We have performed a retrospective review of all patients who underwent ECMO prior CDH repair over a 7\u00a0year period (2015\u20132021). Outcome measures were intra-operative Ph, PCO<jats:sub>2<\/jats:sub>, PO<jats:sub>2<\/jats:sub> and FiO<jats:sub>2<\/jats:sub> at 30\u00a0min, 1\u00a0h 30\u00a0min, and 2\u00a0h 30\u00a0min of surgery, operative time and recurrence rate. Data are shown in median (range).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Eleven patients required ECMO prior CDH repair. Six of eleven (55%) were done thoracoscopically (Group A) and five of eleven (45%) via laparotomy (Group B). Two of six (33%) patients (Group A) were converted to a laparotomy, one of six (16%) patient developed a recurrence, and there was no recurrence in Group B. Two of five (40%) patients died within the first 60\u00a0days of life, whilst there was no death in Group A. Intra-operative values are shown below.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Whilst this is a preliminary report of a limited number of patients, there is no obvious difference of intra-operative blood gas parameters during surgical repair in patients after ECMO. Thoracoscopic CDH repair may be considered in patients after ECMO.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00383-022-05312-x","type":"journal-article","created":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T10:02:43Z","timestamp":1673863363000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Thoracoscopic vs open repair of congenital diaphragmatic hernia after extracorporeal membrane oxygenation: a comparison of intra-operative data"],"prefix":"10.1007","volume":"39","author":[{"given":"Annita","family":"Budzanowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Loukogeorgakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhanya","family":"Mullassery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Blackburn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Curry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Ioannou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usman","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Cross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Giuliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"De Coppi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,16]]},"reference":[{"key":"5312_CR1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2019.07.005","author":"PT Yu","year":"2020","unstructured":"Yu PT, Jen HC, Rice-Townsend S, Guner YS (2020) The role of ECMO in the management of congenital diaphragmatic hernia. Semin Perinatol. https:\/\/doi.org\/10.1053\/j.semperi.2019.07.005","journal-title":"Semin Perinatol"},{"key":"5312_CR2","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1097\/SLA.0b013e31828fab55","volume":"258","author":"M Bishay","year":"2013","unstructured":"Bishay M, Giacomello L, Retrosi G, Thyoka M, Garriboli M, Brierley J et al (2013) Hypercapnia and acidosis during open and thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia: results of a pilot randomized controlled trial. Ann Surg 258:895\u2013900. https:\/\/doi.org\/10.1097\/SLA.0b013e31828fab55","journal-title":"Ann Surg"},{"key":"5312_CR3","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.1007\/s00268-013-2189-0","volume":"37","author":"SH Nam","year":"2013","unstructured":"Nam SH, Cho MJ, Kim DY, Kim SC (2013) Shifting from laparotomy to thoracoscopic repair of congenital diaphragmatic hernia in neonates: early experience. World J Surg 37:2711\u20132716. https:\/\/doi.org\/10.1007\/s00268-013-2189-0","journal-title":"World J Surg"},{"key":"5312_CR4","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1089\/lap.2015.0243","volume":"25","author":"M Lacher","year":"2015","unstructured":"Lacher M, St Peter SD, Laje P, Harmon CM, Ure B, Kuebler JF (2015) Thoracoscopic CDH repair\u2014a survey on opinion and experience among IPEG Members. J Laparoendosc Adv Surg Tech 25:954\u2013957. https:\/\/doi.org\/10.1089\/lap.2015.0243","journal-title":"J Laparoendosc Adv Surg Tech"},{"key":"5312_CR5","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1016\/j.jpedsurg.2008.11.030","volume":"44","author":"DM Gourlay","year":"2009","unstructured":"Gourlay DM, Cassidy LD, Sato TT, Lal DR, Arca MJ (2009) Beyond feasibility: a comparison of newborns undergoing thoracoscopic and open repair of congenital diaphragmatic hernias. J Pediatr Surg 44:1702\u20131707. https:\/\/doi.org\/10.1016\/j.jpedsurg.2008.11.030","journal-title":"J Pediatr Surg"},{"key":"5312_CR6","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1016\/j.jpedsurg.2005.05.036","volume":"40","author":"EY Yang","year":"2005","unstructured":"Yang EY, Allmendinger N, Johnson SM, Chen C, Wilson JM, Fishman SJ (2005) Neonatal thoracoscopic repair of congenital diaphragmatic hernia: Selection criteria for successful outcome. J Pediatr Surg 40:1369\u20131375. https:\/\/doi.org\/10.1016\/j.jpedsurg.2005.05.036","journal-title":"J Pediatr Surg"},{"key":"5312_CR7","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1089\/lap.2016.0583","volume":"28","author":"A Schlager","year":"2018","unstructured":"Schlager A, Arps K, Siddharthan R, Glenn I, Hill SJ, Wulkan ML et al (2018) Thoracoscopic repair of congenital diaphragmatic hernia after extracorporeal membrane oxygenation: feasibility and outcomes. J Laparoendosc Adv Surg Tech 28:774\u2013779. https:\/\/doi.org\/10.1089\/lap.2016.0583","journal-title":"J Laparoendosc Adv Surg Tech"},{"key":"5312_CR8","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1089\/lap.2009.0129","volume":"19","author":"AC Kim","year":"2009","unstructured":"Kim AC, Bryner BS, Akay B, Geiger JD, Hirschl RB, Mychaliska GB (2009) Thoracoscopic repair of congenital diaphragmatic hernia in neonates: lessons learned. J Laparoendosc Adv Surg Tech 19:575\u2013580. https:\/\/doi.org\/10.1089\/lap.2009.0129","journal-title":"J Laparoendosc Adv Surg Tech"},{"key":"5312_CR9","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.jpedsurg.2008.10.013","volume":"44","author":"SD Cho","year":"2009","unstructured":"Cho SD, Krishnaswami S, Mckee JC, Zallen G, Silen ML, Bliss DW (2009) Analysis of 29 consecutive thoracoscopic repairs of congenital diaphragmatic hernia in neonates compared to historical controls. J Pediatr Surg 44:80\u201386. https:\/\/doi.org\/10.1016\/j.jpedsurg.2008.10.013","journal-title":"J Pediatr Surg"},{"key":"5312_CR10","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1055\/s-0040-1703011","volume":"30","author":"M Uecker","year":"2020","unstructured":"Uecker M, Kuebler JF, Ure BM, Schukfeh N (2020) Minimally invasive pediatric surgery: the learning curve. Eur J Pediatr Surg 30:172\u2013180. https:\/\/doi.org\/10.1055\/s-0040-1703011","journal-title":"Eur J Pediatr Surg"},{"key":"5312_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fped.2022.846630","volume":"10","author":"KB Zahn","year":"2022","unstructured":"Zahn KB, Franz AM, Schaible T, Rafat N, B\u00fcttner S, Boettcher M et al (2022) Small bowel obstruction after neonatal repair of congenital diaphragmatic hernia\u2014incidence and risk-factors identified in a large longitudinal cohort-study. Front Pediatr 10:1\u201319. https:\/\/doi.org\/10.3389\/fped.2022.846630","journal-title":"Front Pediatr"},{"key":"5312_CR12","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/j.jpedsurg.2017.03.011","volume":"52","author":"LR Putnam","year":"2017","unstructured":"Putnam LR, Gupta V, Tsao K, Lally PA, Lally KP, Harting MT et al (2017) Factors associated with early recurrence after congenital diaphragmatic hernia repair. J Pediatr Surg 52:928\u2013932. https:\/\/doi.org\/10.1016\/j.jpedsurg.2017.03.011","journal-title":"J Pediatr Surg"},{"key":"5312_CR13","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1016\/j.jpedsurg.2011.03.050","volume":"46","author":"KJ Tsao","year":"2011","unstructured":"Tsao KJ, Lally PA, Lally KP (2011) Minimally invasive repair of congenital diaphragmatic hernia. J Pediatr Surg 46:1158\u20131164. https:\/\/doi.org\/10.1016\/j.jpedsurg.2011.03.050","journal-title":"J Pediatr Surg"},{"key":"5312_CR14","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1002\/uog.20216","volume":"54","author":"CC Style","year":"2019","unstructured":"Style CC, Olutoye OO, Belfort MA, Ayres NA, Cruz SM, Lau PE et al (2019) Fetal endoscopic tracheal occlusion reduces pulmonary hypertension in severe congenital diaphragmatic hernia. Ultrasound Obstet Gynecol 54:752\u2013758. https:\/\/doi.org\/10.1002\/uog.20216","journal-title":"Ultrasound Obstet Gynecol"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-022-05312-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00383-022-05312-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-022-05312-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T18:13:01Z","timestamp":1702577581000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00383-022-05312-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,16]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["5312"],"URL":"https:\/\/doi.org\/10.1007\/s00383-022-05312-x","relation":{},"ISSN":["1437-9813"],"issn-type":[{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,16]]},"assertion":[{"value":"11 November 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 January 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"82"}}