{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T08:16:01Z","timestamp":1788336961284,"version":"build-2803163510"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T00:00:00Z","timestamp":1676073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T00:00:00Z","timestamp":1676073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"DOI":"10.1007\/s00383-023-05394-1","type":"journal-article","created":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T11:37:39Z","timestamp":1676115459000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Incidence and antiviral treatment of cytomegalovirus infection in infants with biliary atresia"],"prefix":"10.1007","volume":"39","author":[{"given":"Ulrika","family":"Liliemark","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan F.","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Fischler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,11]]},"reference":[{"key":"5394_CR1","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/S0022-3468(97)90611-4","volume":"32","author":"M Davenport","year":"1997","unstructured":"Davenport M, Kerkar N, Mieli-Vergani G, Mowat AP, Howard ER (1997) Biliary atresia: the King\u2019s College Hospital Experience (1974\u20131995). J Pediatr Surg 32:479\u2013485. https:\/\/doi.org\/10.1016\/S0022-3468(97)90611-4","journal-title":"J Pediatr Surg"},{"key":"5394_CR2","doi-asserted-by":"publisher","first-page":"1973","DOI":"10.1016\/j.jpedsurg.2006.08.019","volume":"41","author":"M Nio","year":"2006","unstructured":"Nio M, Sano N, Ishii T, Sasaki H, Hayashi Y, Ohi R (2006) Long-term outcome in type I biliary atresia. J Pediatr Surg 41:1973\u20131975. https:\/\/doi.org\/10.1016\/j.jpedsurg.2006.08.019","journal-title":"J Pediatr Surg"},{"key":"5394_CR3","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1016\/j.jhep.2013.01.040","volume":"58","author":"C Chardot","year":"2013","unstructured":"Chardot C, Buet C, Serinet M-O, Golmard J-L, Lachaux A, Roquelaure B et al (2013) Improving outcomes of biliary atresia: French national series 1986\u20132009. J Hepatol 58:1209\u20131217. https:\/\/doi.org\/10.1016\/j.jhep.2013.01.040","journal-title":"J Hepatol"},{"key":"5394_CR4","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1016\/S0022-3468(03)00178-7","volume":"38","author":"M Nio","year":"2003","unstructured":"Nio M, Ohi R, Miyano T, Saeki M, Shiraki K, Tanaka K (2003) Five- and 10-year survival rates after surgery for biliary atresia: a report from the Japanese biliary atresia registry. J Pediatr Surg 38:997\u20131000. https:\/\/doi.org\/10.1016\/S0022-3468(03)00178-7","journal-title":"J Pediatr Surg"},{"key":"5394_CR5","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1034\/j.1600-0676.2001.021003175.x","volume":"21","author":"R Ohi","year":"2001","unstructured":"Ohi R (2001) Surgery for biliary atresia: surgery for biliary atresia. Liver 21:175\u2013182. https:\/\/doi.org\/10.1034\/j.1600-0676.2001.021003175.x","journal-title":"Liver"},{"key":"5394_CR6","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1542\/peds.2005-1267","volume":"117","author":"S-M Chen","year":"2006","unstructured":"Chen S-M (2006) Screening for biliary atresia by infant stool color card in Taiwan. Pediatrics 117:1147\u20131154. https:\/\/doi.org\/10.1542\/peds.2005-1267","journal-title":"Pediatrics"},{"key":"5394_CR7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000007267","volume":"96","author":"Z Song","year":"2017","unstructured":"Song Z, Dong R, Shen Z, Chen G, Yang Y, Zheng S (2017) Surgical outcome and etiologic heterogeneity of infants with biliary atresia who received Kasai operation less than 60 days after birth: a retrospective study. Medicine (Baltimore) 96:e7267. https:\/\/doi.org\/10.1097\/MD.0000000000007267","journal-title":"Medicine (Baltimore)"},{"key":"5394_CR8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2007.05114.x","author":"M-M Tiao","year":"2007","unstructured":"Tiao M-M, Tsai S-S, Kuo H-W, Chen C-L, Yang C-Y (2007) Epidemiological features of biliary atresia in Taiwan, a national study 1996\u20132003. J Gastroenterol Hepatol. https:\/\/doi.org\/10.1111\/j.1440-1746.2007.05114.x","journal-title":"J Gastroenterol Hepatol"},{"key":"5394_CR9","doi-asserted-by":"publisher","first-page":"2090","DOI":"10.1016\/j.jpedsurg.2007.08.035","volume":"42","author":"H Wada","year":"2007","unstructured":"Wada H, Muraji T, Yokoi A, Okamoto T, Sato S, Takamizawa S et al (2007) Insignificant seasonal and geographical variation in incidence of biliary atresia in Japan: a regional survey of over 20 years. J Pediatr Surg 42:2090\u20132092. https:\/\/doi.org\/10.1016\/j.jpedsurg.2007.08.035","journal-title":"J Pediatr Surg"},{"key":"5394_CR10","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1067\/mpd.2002.126001","volume":"141","author":"B Fischler","year":"2002","unstructured":"Fischler B, Haglund B, Hjern A (2002) A population-based study on the incidence and possible pre- and perinatal etiologic risk factors of biliary atresia. J Pediatr 141:217\u2013222. https:\/\/doi.org\/10.1067\/mpd.2002.126001","journal-title":"J Pediatr"},{"key":"5394_CR11","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.jpeds.2017.05.006","volume":"187","author":"PC Hopkins","year":"2017","unstructured":"Hopkins PC, Yazigi N, Nylund CM (2017) Incidence of biliary atresia and timing of hepatoportoenterostomy in the United States. J Pediatr 187:253\u2013257. https:\/\/doi.org\/10.1016\/j.jpeds.2017.05.006","journal-title":"J Pediatr"},{"key":"5394_CR12","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1053\/jhep.2002.34170","volume":"35","author":"DH Perlmutter","year":"2002","unstructured":"Perlmutter DH, Shepherd RW (2002) Extrahepatic biliary atresia: A disease or a phenotype? Extrahepatic biliary atresia: a disease or a phenotype? Hepatology 35:1297\u20131304. https:\/\/doi.org\/10.1053\/jhep.2002.34170","journal-title":"Hepatology"},{"key":"5394_CR13","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/j.1399-3046.2004.00153.x","volume":"8","author":"SV McDiarmid","year":"2004","unstructured":"McDiarmid SV, Anand R, Lindblad AS, The SPLIT Research Group (2004) Studies of pediatric liver transplantation: 2002 update. An overview of demographics, indications, timing, and immunosuppressive practices in pediatric liver transplantation in the United States and Canada. Pediatr Transplant 8:284\u2013294. https:\/\/doi.org\/10.1111\/j.1399-3046.2004.00153.x","journal-title":"Pediatr Transplant"},{"key":"5394_CR14","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1016\/j.jpedsurg.2015.03.001","volume":"50","author":"A Zani","year":"2015","unstructured":"Zani A, Quaglia A, Hadzi\u0107 N, Zuckerman M, Davenport M (2015) Cytomegalovirus-associated biliary atresia: an aetiological and prognostic subgroup. J Pediatr Surg 50:1739\u20131745. https:\/\/doi.org\/10.1016\/j.jpedsurg.2015.03.001","journal-title":"J Pediatr Surg"},{"key":"5394_CR15","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1097\/00005176-199807000-00010","volume":"27","author":"B Fischler","year":"1998","unstructured":"Fischler B, Ehrnst A, Forsgren M, \u00d6rvell C, Nemeth A (1998) The Viral Association of neonatal cholestasis in Sweden: a possible link between cytomegalovirus infection and extrahepatic biliary atresia. J Pediatr Gastroenterol Nutr 27:57\u201364. https:\/\/doi.org\/10.1097\/00005176-199807000-00010","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"5394_CR16","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.jpedsurg.2004.11.035","volume":"40","author":"B Fischler","year":"2005","unstructured":"Fischler B, Woxenius S, Nemeth A, Papadogiannakis N (2005) Immunoglobulin deposits in liver tissue from infants with biliary atresia and the correlation to cytomegalovirus infection. J Pediatr Surg 40:541\u2013546. https:\/\/doi.org\/10.1016\/j.jpedsurg.2004.11.035","journal-title":"J Pediatr Surg"},{"key":"5394_CR17","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1177\/0009922811406264","volume":"51","author":"Y Xu","year":"2012","unstructured":"Xu Y, Yu J, Zhang R, Yin Y, Ye J, Tan L et al (2012) The perinatal infection of cytomegalovirus is an important etiology for biliary atresia in China. Clin Pediatr (Phila) 51:109\u2013113. https:\/\/doi.org\/10.1177\/0009922811406264","journal-title":"Clin Pediatr (Phila)"},{"key":"5394_CR18","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1016\/j.jpedsurg.2018.12.014","volume":"54","author":"F Parolini","year":"2019","unstructured":"Parolini F, Hadzic N, Davenport M (2019) Adjuvant therapy of cytomegalovirus IgM + ve associated biliary atresia: prima facie evidence of effect. J Pediatr Surg 54:1941\u20131945. https:\/\/doi.org\/10.1016\/j.jpedsurg.2018.12.014","journal-title":"J Pediatr Surg"},{"key":"5394_CR19","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s12519-008-0024-8","volume":"4","author":"C Shen","year":"2008","unstructured":"Shen C, Zheng S, Wang W, Xiao X-M (2008) Relationship between prognosis of biliary atresia and infection of cytomegalovirus. World J Pediatr 4:123\u2013126. https:\/\/doi.org\/10.1007\/s12519-008-0024-8","journal-title":"World J Pediatr"},{"key":"5394_CR20","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.710450","volume":"9","author":"Y Zhao","year":"2021","unstructured":"Zhao Y, Xu X, Liu G, Yang F, Zhan J (2021) Prognosis of biliary atresia associated with cytomegalovirus: a meta-analysis. Front Pediatr 9:710450. https:\/\/doi.org\/10.3389\/fped.2021.710450","journal-title":"Front Pediatr"},{"key":"5394_CR21","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1111\/j.1651-2227.2009.01416.x","volume":"98","author":"B Fischler","year":"2009","unstructured":"Fischler B, Svensson JF, Nemeth A (2009) Early cytomegalovirus infection and the long-term outcome of biliary atresia. Acta Paediatr 98:1600\u20131602. https:\/\/doi.org\/10.1111\/j.1651-2227.2009.01416.x","journal-title":"Acta Paediatr"},{"key":"5394_CR22","doi-asserted-by":"publisher","first-page":"945","DOI":"10.3390\/jcm11040945","volume":"11","author":"B Fischler","year":"2022","unstructured":"Fischler B, Czubkowski P, Dezsofi A, Liliemark U, Socha P, Sokol RJ et al (2022) Incidence, impact and treatment of ongoing CMV infection in patients with biliary atresia in four European centres. J Clin Med 11:945. https:\/\/doi.org\/10.3390\/jcm11040945","journal-title":"J Clin Med"},{"key":"5394_CR23","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1111\/j.1399-3062.2008.00313.x","volume":"10","author":"C Kullberg-Lindh","year":"2008","unstructured":"Kullberg-Lindh C, Olofsson S, Brune M, Lindh M (2008) Comparison of serum and whole blood levels of cytomegalovirus and Epstein-Barr virus DNA. Transpl Infect Dis 10:308\u2013315. https:\/\/doi.org\/10.1111\/j.1399-3062.2008.00313.x","journal-title":"Transpl Infect Dis"},{"key":"5394_CR24","unstructured":"Swedish Medical Birth Register [database online]. Socialstyrelsen n.d. https:\/\/www.socialstyrelsen.se\/statistik-och-data\/register\/alla-register\/medicinska-fodelseregistret\/. Accessed 7 Jan 2021"},{"key":"5394_CR25","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/1471-2334-5-108","volume":"5","author":"AM De Tommaso","year":"2005","unstructured":"De Tommaso AM, Andrade PD, Costa SC, Escanhoela CA, Hessel G (2005) High frequency of human cytomegalovirus DNA in the liver of infants with extrahepatic neonatal cholestasis. BMC Infect Dis 5:108. https:\/\/doi.org\/10.1186\/1471-2334-5-108","journal-title":"BMC Infect Dis"},{"key":"5394_CR26","doi-asserted-by":"publisher","first-page":"890","DOI":"10.7196\/SAMJ.6163","volume":"102","author":"SW Moore","year":"2012","unstructured":"Moore SW, Zabiegaj-Zwick C, Nel E (2012) Problems related to CMV infection and biliary atresia. S Afr Med J 102:890. https:\/\/doi.org\/10.7196\/SAMJ.6163","journal-title":"S Afr Med J"},{"key":"5394_CR27","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1542\/peds.97.6.828","volume":"97","author":"PI Tarr","year":"1996","unstructured":"Tarr PI, Haas JE, Christie DL (1996) Biliary atresia, cytomegalovirus, and age at referral. Pediatrics 97:828\u2013831","journal-title":"Pediatrics"},{"key":"5394_CR28","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1111\/j.1399-3046.2005.00257.x","volume":"9","author":"RB Fjaer","year":"2005","unstructured":"Fjaer RB, Bruu A-L, Nordb\u00f8 SA (2005) Extrahepatic bile duct atresia and viral involvement. Pediatr Transplant 9:68\u201373. https:\/\/doi.org\/10.1111\/j.1399-3046.2005.00257.x","journal-title":"Pediatr Transplant"},{"key":"5394_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2020.100286","volume":"23","author":"D Zhao","year":"2021","unstructured":"Zhao D, Gong X, Li Y, Sun X, Chen Y, Deng Z et al (2021) Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study. Ann Hepatol 23:100286. https:\/\/doi.org\/10.1016\/j.aohep.2020.100286","journal-title":"Ann Hepatol"},{"key":"5394_CR30","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1097\/INF.0000000000001889","volume":"37","author":"A Goel","year":"2018","unstructured":"Goel A, Chaudhari S, Sutar J, Bhonde G, Bhatnagar S, Patel V et al (2018) Detection of cytomegalovirus in liver tissue by polymerase chain reaction in infants with neonatal cholestasis. Pediatr Infect Dis J 37:632\u2013636. https:\/\/doi.org\/10.1097\/INF.0000000000001889","journal-title":"Pediatr Infect Dis J"},{"key":"5394_CR31","doi-asserted-by":"publisher","first-page":"F130","DOI":"10.1136\/fn.80.2.F130","volume":"80","author":"B Fischler","year":"1999","unstructured":"Fischler B, Rodensjo P, Nemeth A, Forsgren M, Lewensohn-Fuchs I (1999) Cytomegalovirus DNA detection on Guthrie cards in patients with neonatal cholestasis. Arch Dis Child - Fetal Neonatal Ed 80:F130\u2013F134. https:\/\/doi.org\/10.1136\/fn.80.2.F130","journal-title":"Arch Dis Child - Fetal Neonatal Ed"},{"key":"5394_CR32","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.jpeds.2012.12.085","volume":"163","author":"C-Y Chiu","year":"2013","unstructured":"Chiu C-Y, Chen P-H, Chan C-F, Chang M-H, Wu T-C (2013) Biliary atresia in preterm infants in Taiwan: a nationwide survey. J Pediatr 163:100-103.e1. https:\/\/doi.org\/10.1016\/j.jpeds.2012.12.085","journal-title":"J Pediatr"},{"key":"5394_CR33","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1097\/MPG.0000000000001692","volume":"65","author":"DBE van Wessel","year":"2017","unstructured":"van Wessel DBE, Boere T, Hulzebos CV, de Kleine RHJ, Verkade HJ, Hulscher JBF (2017) Preterm infants with biliary atresia: a nationwide cohort analysis from The Netherlands. J Pediatr Gastroenterol Nutr 65:370\u2013374. https:\/\/doi.org\/10.1097\/MPG.0000000000001692","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"5394_CR34","doi-asserted-by":"publisher","first-page":"001","DOI":"10.1055\/s-0038-1668146","volume":"29","author":"Z Wong","year":"2019","unstructured":"Wong Z, Davenport M (2019) What happens after Kasai for biliary atresia? A European multicenter survey. Eur J Pediatr Surg 29:001\u2013006. https:\/\/doi.org\/10.1055\/s-0038-1668146","journal-title":"Eur J Pediatr Surg"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-023-05394-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00383-023-05394-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-023-05394-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T18:15:49Z","timestamp":1702577749000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00383-023-05394-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,11]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["5394"],"URL":"https:\/\/doi.org\/10.1007\/s00383-023-05394-1","relation":{},"ISSN":["1437-9813"],"issn-type":[{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,11]]},"assertion":[{"value":"28 January 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"117"}}