{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T02:39:27Z","timestamp":1784774367568,"version":"3.55.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"DOI":"10.1007\/s00383-023-05470-6","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T12:22:16Z","timestamp":1681993336000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Incidence, predictors and outcomes of redo pancreatectomy in infants with congenital hyperinsulinism: a 16-year tertiary center experience"],"prefix":"10.1007","volume":"39","author":[{"given":"Ali","family":"Al-Ameer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afrah","family":"Alsomali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakaria","family":"Habib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,20]]},"reference":[{"key":"5470_CR1","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.jpedsurg.2008.10.120","volume":"44","author":"S Al-Shanafey","year":"2009","unstructured":"Al-Shanafey S, Habib Z, AlNassar S (2009) Laparoscopic pancreatectomy for persistent hyperinsulinemic hypoglycemia of infancy. J Pediatr Surg 44:134\u2013138. https:\/\/doi.org\/10.1016\/j.jpedsurg.2008.10.120. (Discussion 138)","journal-title":"J Pediatr Surg"},{"key":"5470_CR2","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1542\/peds.107.3.476","volume":"107","author":"F Menni","year":"2001","unstructured":"Menni F, de Lonlay P, Sevin C et al (2001) Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia. Pediatrics 107:476\u2013479. https:\/\/doi.org\/10.1542\/peds.107.3.476","journal-title":"Pediatrics"},{"key":"5470_CR3","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/s0022-3468(83)80277-2","volume":"18","author":"M Carcassonne","year":"1983","unstructured":"Carcassonne M, DeLarue A, LeTourneau JN (1983) Surgical treatment of organic pancreatic hypoglycemia in the pediatric age. J Pediatr Surg 18:75\u201379. https:\/\/doi.org\/10.1016\/s0022-3468(83)80277-2","journal-title":"J Pediatr Surg"},{"key":"5470_CR4","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1111\/cen.14152","volume":"92","author":"C Worth","year":"2020","unstructured":"Worth C, Yau D, Salomon Estebanez M et al (2020) Complexities in the medical management of hypoglycaemia due to congenital hyperinsulinism. Clin Endocrinol 92:387\u2013395. https:\/\/doi.org\/10.1111\/cen.14152","journal-title":"Clin Endocrinol"},{"key":"5470_CR5","doi-asserted-by":"publisher","first-page":"99","DOI":"10.4103\/0971-9261.98119","volume":"17","author":"P Goel","year":"2012","unstructured":"Goel P, Choudhury SR (2012) Persistent hyperinsulinemic hypoglycemia of infancy: an overview of current concepts. J Indian Assoc Pediatr Surg 17:99\u2013103. https:\/\/doi.org\/10.4103\/0971-9261.98119","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"5470_CR6","first-page":"574","volume-title":"The surgery of infancy and childhood","author":"RE Gross","year":"1953","unstructured":"Gross RE (1953) The surgery of infancy and childhood. WB Saunders, Philadelphia, p 574"},{"key":"5470_CR7","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1007\/s12262-013-0999-9","volume":"77","author":"R Redkar","year":"2015","unstructured":"Redkar R, Karkera PJ, Krishnan J et al (2015) Subtotal pancreatectomy for congenital hyperinsulinism: our experience and review of literature. Indian J Surg 77:778\u2013782. https:\/\/doi.org\/10.1007\/s12262-013-0999-9","journal-title":"Indian J Surg"},{"key":"5470_CR8","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1007\/BF02072204","volume":"150","author":"E Sch\u00f6nau","year":"1991","unstructured":"Sch\u00f6nau E, Deeg KH, Huemmer HP et al (1991) Pancreatic growth and function following surgical treatment of nesidioblastosis in infancy. Eur J Pediatr 150:550\u2013553. https:\/\/doi.org\/10.1007\/BF02072204","journal-title":"Eur J Pediatr"},{"key":"5470_CR9","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1530\/eje.0.1490043","volume":"149","author":"T Meissner","year":"2003","unstructured":"Meissner T, Wendel U, Burgard P et al (2003) Long-term follow-up of 114 patients with congenital hyperinsulinism. Eur J Endocrinol 149:43\u201351. https:\/\/doi.org\/10.1530\/eje.0.1490043","journal-title":"Eur J Endocrinol"},{"key":"5470_CR10","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/S0022-3468(80)80395-2","volume":"15","author":"M Schiller","year":"1980","unstructured":"Schiller M, Krausz M, Meyer S et al (1980) Neonatal hyperinsulinism\u2014surgical and pathologic considerations. J Pediatr Surg 15:16\u201320. https:\/\/doi.org\/10.1016\/S0022-3468(80)80395-2","journal-title":"J Pediatr Surg"},{"key":"5470_CR11","doi-asserted-by":"publisher","first-page":"103","DOI":"10.2147\/RRED.S56608","volume":"5","author":"AM Ackermann","year":"2015","unstructured":"Ackermann AM, Palladino AA (2015) Managing congenital hyperinsulinism: improving outcomes with a multidisciplinary approach. RRED 5:103\u2013117. https:\/\/doi.org\/10.2147\/RRED.S56608","journal-title":"RRED"},{"key":"5470_CR12","doi-asserted-by":"publisher","first-page":"4133","DOI":"10.1210\/jc.2015-2539","volume":"100","author":"K Lord","year":"2015","unstructured":"Lord K, Radcliffe J, Gallagher PR et al (2015) High risk of diabetes and neurobehavioral deficits in individuals with surgically treated hyperinsulinism. J Clin Endocrinol Metab 100:4133\u20134139. https:\/\/doi.org\/10.1210\/jc.2015-2539","journal-title":"J Clin Endocrinol Metab"},{"key":"5470_CR13","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/0022-3468(93)90039-N","volume":"28","author":"GA Reyes","year":"1993","unstructured":"Reyes GA, Fowler CL, Pokorny WJ (1993) Pancreatic anatomy in children: emphasis on its importance to pancreatectomy. J Pediatr Surg 28:712\u2013715. https:\/\/doi.org\/10.1016\/0022-3468(93)90039-N","journal-title":"J Pediatr Surg"},{"key":"5470_CR14","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1210\/jc.2015-3651","volume":"101","author":"CA Stanley","year":"2016","unstructured":"Stanley CA (2016) Perspective on the genetics and diagnosis of congenital hyperinsulinism disorders. J Clin Endocrinol Metab 101:815\u2013826. https:\/\/doi.org\/10.1210\/jc.2015-3651","journal-title":"J Clin Endocrinol Metab"},{"key":"5470_CR15","doi-asserted-by":"publisher","first-page":"169","DOI":"10.4274\/jcrpe.821","volume":"4","author":"Z Mohamed","year":"2012","unstructured":"Mohamed Z, Arya VB, Hussain K (2012) Hyperinsulinaemic hypoglycaemia:genetic mechanisms, diagnosis and management. J Clin Res Pediatr Endocrinol 4:169\u2013181. https:\/\/doi.org\/10.4274\/jcrpe.821","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"5470_CR16","doi-asserted-by":"publisher","first-page":"69","DOI":"10.4274\/jcrpe.2017.S007","volume":"9","author":"H Demirbilek","year":"2017","unstructured":"Demirbilek H, Hussain K (2017) Congenital hyperinsulinism: diagnosis and treatment update. J Clin Res Pediatr Endocrinol 9:69\u201387. https:\/\/doi.org\/10.4274\/jcrpe.2017.S007","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"5470_CR17","first-page":"1002","volume":"34","author":"AE Al-Agha","year":"2013","unstructured":"Al-Agha AE, Ahmad IA (2013) Characterization of the ABCC8 gene mutation and phenotype in patients with congenital hyperinsulinism in western Saudi Arabia. Saudi Med J 34:1002\u20131006","journal-title":"Saudi Med J"},{"key":"5470_CR18","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1053\/j.sempedsurg.2010.10.009","volume":"20","author":"A Pierro","year":"2011","unstructured":"Pierro A, Nah SA (2011) Surgical management of congenital hyperinsulinism of infancy. Semin Pediatr Surg 20:50\u201353. https:\/\/doi.org\/10.1053\/j.sempedsurg.2010.10.009","journal-title":"Semin Pediatr Surg"},{"key":"5470_CR19","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1159\/000111789","volume":"69","author":"K Hussain","year":"2008","unstructured":"Hussain K (2008) Diagnosis and management of hyperinsulinaemic hypoglycaemia of infancy. Horm Res 69:2\u201313. https:\/\/doi.org\/10.1159\/000111789","journal-title":"Horm Res"},{"key":"5470_CR20","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.jpedsurg.2018.10.030","volume":"54","author":"NS Adzick","year":"2019","unstructured":"Adzick NS, De Leon DD, States LJ et al (2019) Surgical treatment of congenital hyperinsulinism: Results from 500 pancreatectomies in neonates and children. J Pediatr Surg 54:27\u201332. https:\/\/doi.org\/10.1016\/j.jpedsurg.2018.10.030","journal-title":"J Pediatr Surg"},{"key":"5470_CR21","doi-asserted-by":"publisher","first-page":"863184","DOI":"10.3389\/fendo.2022.863184","volume":"13","author":"M Danowitz","year":"2022","unstructured":"Danowitz M, De Leon DD (2022) The role of GLP-1 signaling in hypoglycemia due to hyperinsulinism. Front Endocrinol 13:863184. https:\/\/doi.org\/10.3389\/fendo.2022.863184","journal-title":"Front Endocrinol"},{"key":"5470_CR22","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1210\/jc.2008-1263","volume":"94","author":"AA Palladino","year":"2009","unstructured":"Palladino AA, Sayed S, Levitt Katz LE et al (2009) Increased glucagon-like peptide-1 secretion and postprandial hypoglycemia in children after Nissen fundoplication. J Clin Endocrinol Metab 94:39\u201344. https:\/\/doi.org\/10.1210\/jc.2008-1263","journal-title":"J Clin Endocrinol Metab"},{"key":"5470_CR23","doi-asserted-by":"publisher","first-page":"2236","DOI":"10.1007\/s00125-005-1933-x","volume":"48","author":"ME Patti","year":"2005","unstructured":"Patti ME, McMahon G, Mun EC et al (2005) Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 48:2236\u20132240. https:\/\/doi.org\/10.1007\/s00125-005-1933-x","journal-title":"Diabetologia"},{"key":"5470_CR24","first-page":"67","volume":"63","author":"C Bizzarri","year":"2011","unstructured":"Bizzarri C, Cervoni M, Crea F et al (2011) Dumping syndrome: an unusual cause of severe hyperinsulinemic hypoglycemia in neurologically impaired children with gastrostomy. Minerva Pediatr 63:67\u201371","journal-title":"Minerva Pediatr"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-023-05470-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00383-023-05470-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-023-05470-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T18:23:15Z","timestamp":1702578195000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00383-023-05470-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,20]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["5470"],"URL":"https:\/\/doi.org\/10.1007\/s00383-023-05470-6","relation":{},"ISSN":["1437-9813"],"issn-type":[{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,20]]},"assertion":[{"value":"12 April 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethical approval was waived by the local Research Ethics Committee of King Faisal Specialist Hospital and Research Center in view of the retrospective nature of the study and all the procedures being performed were part of the routine care.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"A waiver of informed consent was granted by the institutional review board for this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"183"}}