{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:08:40Z","timestamp":1761541720802,"version":"3.30.2"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>National data from the United Kingdom reported in 2016 have suggested that almost one quarter of babies with anorectal malformation (ARM) have a delay in diagnosis. The UK\u2019s Newborn Infant Physical Examination dictates a perineal examination should be performed within 72\u00a0h of birth. We sought to describe a tertiary single-centre experience of late presentation in the most recent 5\u00a0years.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A single-centre prospective registry of ARM patients (July 2018\u2013March 2024) was analysed. Timing of presentation with anomaly was noted. Patients presenting\u2009&gt;\u200972\u00a0h or having been discharged home were defined as a delayed diagnosis. Factors associated with delayed diagnosis were noted.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty patients were included, of whom nine (15%) were diagnosed after 72\u00a0h [range 4\u2013279\u00a0days]. This represents a non-significant improvement compared to 39\/174 (22%) late diagnosed cases in the BAPS-CASS cohort from 2016 to 17 (<jats:italic>p<\/jats:italic>\u2009=\u20090.188). Presenting symptoms of obstruction (i.e. distension, vomiting, megarectum) were more common in late diagnosed patients (4\/9 (44%) vs. 1\/51(2%); <jats:italic>p<\/jats:italic>\u2009=\u20090.001). Anomalies producing meconium on the perineum were more likely to be diagnosed late (8\/32 (25%) vs 1\/28 (4%); <jats:italic>p<\/jats:italic>\u2009=\u20090.029). Complications and changes to clinical management for these cases are presented.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Although our regional rates of late diagnosis appear to be lower than previously reported national rates, there remains a significant number of infants who are diagnosed late especially those with visible perineal openings. These infants are more commonly symptomatic; entraining additional risks associated with an emergency presentation.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00383-024-05765-2","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T09:02:07Z","timestamp":1720170127000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Late diagnosis of anorectal malformation: how good is good enough?"],"prefix":"10.1007","volume":"40","author":[{"given":"Joseph","family":"Davidson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indre","family":"Zaparackaite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Holbrook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hemanshoo","family":"Thakkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,5]]},"reference":[{"key":"5765_CR1","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1111\/ans.15374","volume":"89","author":"P Kruger","year":"2019","unstructured":"Kruger P, Teague WJ, Khanal R et al (2019) Delayed diagnosis of anorectal malformations in neonates. ANZ J Surg 89:1253\u20131255. https:\/\/doi.org\/10.1111\/ans.15374","journal-title":"ANZ J Surg"},{"key":"5765_CR2","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/s00383-020-04843-5","volume":"37","author":"G Divya","year":"2021","unstructured":"Divya G, Kundal VK, Debnath PR et al (2021) Delayed presentation of anorectal malformations in a tertiary care hospital in India. Pediatr Surg Int 37:451\u2013456. https:\/\/doi.org\/10.1007\/s00383-020-04843-5","journal-title":"Pediatr Surg Int"},{"key":"5765_CR3","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00383-016-3866-5","volume":"32","author":"S Govender","year":"2016","unstructured":"Govender S, Wiersma R (2016) Delayed diagnosis of anorectal malformations (ARM): causes and consequences in a resource-constrained environment. Pediatr Surg Int 32:369\u2013375. https:\/\/doi.org\/10.1007\/s00383-016-3866-5","journal-title":"Pediatr Surg Int"},{"key":"5765_CR4","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1687868","author":"B Aldeiri","year":"2019","unstructured":"Aldeiri B, Davidson J, Eaton S et al (2019) Variations in the Detection of anorectal anomalies at birth among European Cities. Eur J Pediatr Surg. https:\/\/doi.org\/10.1055\/s-0039-1687868","journal-title":"Eur J Pediatr Surg"},{"key":"5765_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2024.03.009","author":"A-M Long","year":"2024","unstructured":"Long A-M, Davidson JR, Tyraskis A et al (2024) A Population-based cohort study on diagnosis and early management of anorectal malformation in the UK and Ireland. 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