{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:00:13Z","timestamp":1792854013440,"version":"4.5.0"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To evaluate the evolution of fertility preservation surgery in children and young adults at high risk of infertility from a single centre to a networked \u2018Hub and Spoke\u2019 service.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A case note review of patients referred for ovarian or testicular cryopreservation between Jan 2013 and Dec 2023. Demographic data, procurement numbers, and site of procurement were collected. Specialist feedback was obtained to identify the challenges faced.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Over time, the number of referrals increased from 4 to 349 patients per year with the number of Spoke centres rising to 36 ovarian and 16 testicular. In 2013\u20132014; 100%\u00a0of procurement was ovarian as compared to 2023; 51% ovarian, 49% testicular. Of the 395 referrals in 2021, 81% (n\u2009=\u2009319) went on to have procurement and storage of tissue. Between 2013 and 2016, 96% of cases were performed at the Hub. In 2023, 53\/349 (15%) cases were performed at the Hub with the remaining 296 (85%) procured at Spoke sites. Surgical issues such as access to theatre, variation and availability of surgical equipment, thermal injury to ovarian tissue and variation in the size of the testicular specimen were identified.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The Hub and Spoke model successfully delivers treatment to patients close to home as safely possible within their local treatment centre.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00383-024-05770-5","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T18:01:34Z","timestamp":1721412094000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Fertility preservation service for children and young adults at high risk of infertility; the hub and spoke model"],"prefix":"10.1007","volume":"40","author":[{"given":"Harmit","family":"Ghattaura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian M.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kokila","family":"Lakhoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"issue":"2","key":"5770_CR1","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1089\/bio.2020.0124","volume":"19","author":"K Hinkle","year":"2021","unstructured":"Hinkle K, Orwig KE, Valli-Pulaski H et al (2021) Cryopreservation of ovarian tissue for pediatric fertility. Biopreserv Biobank 19(2):130\u2013135","journal-title":"Biopreserv Biobank"},{"issue":"4","key":"5770_CR2","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s10815-018-1144-2","volume":"35","author":"SE Gellert","year":"2018","unstructured":"Gellert SE, Pors SE, Kristensen SG et al (2018) Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort. J Assist Reprod Genet 35(4):561\u2013570","journal-title":"J Assist Reprod Genet"},{"issue":"3","key":"5770_CR3","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1159\/000499054","volume":"46","author":"EC Rivas Leonel","year":"2019","unstructured":"Rivas Leonel EC, Lucci CM et al (2019) Cryopreservation of human ovarian tissue: a review. Transfus Med Hemother 46(3):173\u2013181","journal-title":"Transfus Med Hemother"},{"issue":"13","key":"5770_CR4","first-page":"1","volume":"30","author":"M von Wolff","year":"2019","unstructured":"von Wolff M, Andersen CY, Woodruff TK, Nawroth F (2019) FertiPROTEKT, oncofertility consortium and the danish fertility-preservation networks \u2013 what can we learn from their experiences? Clin Med Insights Reprod Health 30(13):1\u201317","journal-title":"Clin Med Insights Reprod Health"},{"key":"5770_CR5","unstructured":"Children\u2019s Cancer and Leukaemia Group. (2019) Oncofertility Consensus Document. Update."},{"issue":"1","key":"5770_CR6","doi-asserted-by":"publisher","first-page":"26","DOI":"10.7861\/clinmed.2020-0579","volume":"21","author":"L Zhang","year":"2021","unstructured":"Zhang L, Ogungbemi A, Trippier S et al (2021) Hub-and-spoke model for thrombectomy service in UK NHS practice. Clin Med (Lond) 21(1):26\u201331","journal-title":"Clin Med (Lond)"},{"issue":"1","key":"5770_CR7","doi-asserted-by":"publisher","DOI":"10.1111\/cch.13154","volume":"50","author":"KE Harding","year":"2024","unstructured":"Harding KE, Lewis AK, Dennett A et al (2024) An evidence-based demand management strategy using a hub and spoke training model reduces waiting time for children\u2019s therapy services: an implementation trial. Child Care Health Dev 50(1):e13154","journal-title":"Child Care Health Dev"},{"issue":"11","key":"5770_CR8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.123.010126","volume":"16","author":"V Gee Lim","year":"2023","unstructured":"Gee Lim V, He H, Lachlan T et al (2023) Use of satellite-sites for percutaneous cardiac ablations (the Hub-and-Spoke Model): lessons from the COVID-19 Pandemic. Circ Cardiovasc Qual Outcomes 16(11):e010126","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"17","key":"5770_CR9","first-page":"1605","volume":"25","author":"R Venkataramanan","year":"2023","unstructured":"Venkataramanan R, Pradhan A, Kumar A et al (2023) Role of digital health in coordinating patient care in a hub-and-spoke hierarchy of cancer care facilities: a scoping review. Ecancermedicalscience 25(17):1605","journal-title":"Ecancermedicalscience"},{"key":"5770_CR10","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s43159-022-00161-8","volume":"18","author":"K Metcalfe","year":"2022","unstructured":"Metcalfe K, Ghattaura H, Elbourne C et al (2022) Conventional 3 port vs single incision laparoscopic oophorectomy for ovarian cryopreservation in paediatric surgery; a retrospective case-note review. Ann Pediatr Surg 18:24","journal-title":"Ann Pediatr Surg"},{"key":"5770_CR11","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1126\/science.aav2914","volume":"363","author":"AP Fayomi","year":"2019","unstructured":"Fayomi AP, Peters K, Sukhwani M et al (2019) Autologous grafting of cryopreserved prepubertal rhesus testis produces sperm and offspring. Science 363:1314\u20131319","journal-title":"Science"},{"issue":"3","key":"5770_CR12","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.jmig.2017.10.007","volume":"25","author":"G Karavani","year":"2018","unstructured":"Karavani G, Schachter-Safrai N, Chill HH et al (2018) Single-incision laparoscopic surgery for ovarian tissue cryopreservation. 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