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The databases MEDLINE, Complementary Index, Academic Search Ultimate, CINAHL Complete, Directory of Open Access Journals, and Supplemental Index were systematically searched using keywords adapted to each database. To evaluate the quality of randomized controlled trials (RCTs), the Cochrane Risk of Bias Tool (RoB 2) was utilized. The data analysis was conducted using Comprehensive Meta-Analysis (CMA) software version 3. Meta-analyses were performed on studies that provided continuous statistical data suitable for estimating overall effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Virtual reality significantly reduced preoperative and intraoperative anxiety to a moderate degree (p\u2009&lt;\u20090.001 and p\u2009=\u20090.002). However, its effects on postoperative pain (p\u2009=\u20090.071) and delirium (p\u2009=\u20090.307) were not statistically significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Virtual reality is an effective intervention for reducing anxiety in pediatric surgical patients. However, considering the heterogeneity and methodological differences among the included studies, further randomized controlled trials (RCTs) are necessary to strengthen these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00383-025-06084-w","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T09:57:59Z","timestamp":1749549479000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of virtual reality on pain, anxiety, and delirium in pediatric surgery: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7243-0734","authenticated-orcid":false,"given":"Se\u00e7il","family":"Taylan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4209-2615","authenticated-orcid":false,"given":"K\u0131zbes Meral","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-5682","authenticated-orcid":false,"given":"\u0130lknur","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"issue":"2","key":"6084_CR1","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1007\/s10143-020-01314-2","volume":"44","author":"TR Meling","year":"2021","unstructured":"Meling TR, Meling TR (2021) The impact of surgical simulation on patient outcomes: a systematic review and meta-analysis. 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