{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:15:50Z","timestamp":1778584550765,"version":"3.51.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005639","name":"Universidade De S\u00e3o Paulo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005639","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Acute appendicitis is the leading cause of abdominal surgery. This study evaluated outcomes of transumbilical single-incision laparoscopic appendectomy (TSILA) compared with conventional laparoscopy and open surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective study of 550 pediatric patients (0\u201318 years) undergoing an appendectomy (2020\u20132023) at a tertiary center was conducted. Patients were stratified by technique and appendicitis grade (I\u2013IV). Data were analyzed using Pearson\u2019s Chi-squared and ANOVA tests (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      TSILA accounted for 34.5% of cases (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009190) and showed shorter hospital stays (2.98 days) compared to conventional laparoscopy (4.23 days) and open surgery (5.58 days) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Postoperative fever was lower with TSILA (7.9%) compared to conventional laparoscopy (12.7%) and open surgery (27.5%) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). Wound infection rates were similar between TSILA and conventional laparoscopy, both lower than open surgery. Postoperative antibiotic use was lowest with TSILA (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). In Grade IV, TSILA showed shorter hospital stay, with no significant differences in complications or antibiotic use.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TSILA is a safe option, associated with shorter hospital stays and reduced antibiotic use in Grades I\u2013III. In advanced cases, benefits were limited to shorter hospitalization, with outcomes comparable to conventional techniques.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00383-026-06448-w","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T10:46:28Z","timestamp":1778582788000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transumbilical single-port appendectomy in children: a retrospective study"],"prefix":"10.1007","volume":"42","author":[{"given":"Lu\u00edsa Gomes","family":"Berto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina Lopez","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina Vieira","family":"Durante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tales Rubens","family":"de Nadai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Ant\u00f4nio","family":"Marton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"6448_CR1","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1016\/S0140-6736(15)00275-5","volume":"386","author":"A Bhangu","year":"2015","unstructured":"Bhangu A, S\u00f8reide K, Di Saverio S et al (2015) Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. Lancet 386:1278\u20131287. https:\/\/doi.org\/10.1016\/S0140-6736(15)00275-5","journal-title":"Lancet"},{"key":"6448_CR2","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.jpedsurg.2015.10.002","volume":"51","author":"JF Svensson","year":"2016","unstructured":"Svensson JF, Patkova B, Almstr\u00f6m M et al (2016) Outcome after introduction of laparoscopic appendectomy in children: a cohort study. J Pediatr Surg 51:449\u2013453. https:\/\/doi.org\/10.1016\/j.jpedsurg.2015.10.002","journal-title":"J Pediatr Surg"},{"key":"6448_CR3","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1503\/cjs.012715","volume":"58","author":"C Blackmore","year":"2015","unstructured":"Blackmore C, Tanyingo D, Kaplan GG et al (2015) A comparison of outcomes between laparoscopic and open appendectomy in Canada. Can J Surg 58:431\u2013432. https:\/\/doi.org\/10.1503\/cjs.012715","journal-title":"Can J Surg"},{"key":"6448_CR4","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1055\/s-2007-1021466","volume":"15","author":"K Semm","year":"1983","unstructured":"Semm K (1983) Endoscopic appendectomy. Endoscopy 15:59\u201364. https:\/\/doi.org\/10.1055\/s-2007-1021466","journal-title":"Endoscopy"},{"key":"6448_CR5","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/BF00591150","volume":"1","author":"JH Schreiber","year":"1987","unstructured":"Schreiber JH (1987) Early experience with laparoscopic appendectomy in women. Surg Endosc 1:211\u2013216. https:\/\/doi.org\/10.1007\/BF00591150","journal-title":"Surg Endosc"},{"key":"6448_CR6","first-page":"721","volume":"88","author":"MA Pelosi","year":"1991","unstructured":"Pelosi MA, Pelosi MA 3rd (1991) Laparoscopic hysterectomy with bilateral salpingo-oophorectomy using a single umbilical puncture. 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Int J Surg 36:261\u2013264. https:\/\/doi.org\/10.1016\/j.ijsu.2016.11.004","journal-title":"Int J Surg"},{"issue":"6","key":"6448_CR9","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1016\/j.jpedsurg.2010.02.090","volume":"45","author":"JD Fraser","year":"2010","unstructured":"Fraser JD et al (2010) A complete course of intravenous antibiotics versus a combination of intravenous and oral antibiotics for perforated appendicitis in children: a prospective randomized trial. J Pediatr Surg 45(6):1198\u20131202","journal-title":"J Pediatr Surg"},{"key":"6448_CR10","doi-asserted-by":"publisher","unstructured":"Pogoreli\u0107 Z, Domjanovi\u0107 J, Juki\u0107 M, Poklepovi\u0107 Peri\u010di\u0107 T (2020) Acute appendicitis in children younger than five years of age: diagnostic challenge for pediatric surgeons. Surg Infect 21(3):239\u2013245. https:\/\/doi.org\/10.1089\/sur.2019.175","DOI":"10.1089\/sur.2019.175"},{"key":"6448_CR11","doi-asserted-by":"publisher","unstructured":"Esposito C, Becmeur F, Steyaert H, Szavay P (2019) ESPES Manual of Pediatric Minimally Invasive Surgery. In Springer eBooks. https:\/\/doi.org\/10.1007\/978-3-030-00964-9","DOI":"10.1007\/978-3-030-00964-9"},{"key":"6448_CR12","doi-asserted-by":"publisher","unstructured":"Dorman RM, Ventro G, Rothstein DH, Vali K (2017) Safety of perioperative ketorolac administration in pediatric appendectomy. J Surg Res 218:232\u2013236. https:\/\/doi.org\/10.1016\/j.jss.2017.05.087","DOI":"10.1016\/j.jss.2017.05.087"},{"key":"6448_CR13","doi-asserted-by":"publisher","unstructured":"Gorter RR, The SM, Gorter-Stam MA, Eker HH, Bakx R, van der Lee JH, Heij HA (2017) Systematic review of nonoperative versus operative treatment of uncomplicated appendicitis. 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Informed consent for publication was obtained from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"230"}}