{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T01:01:51Z","timestamp":1784595711414,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Surg Int"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Colonic diverticulitis is rare in the pediatric population and often presents with nonspecific symptoms that may be misdiagnosed as other causes of acute abdominal pain, such as appendicitis, leading to diagnostic uncertainty and variability in management. We report a case of pediatric colonic diverticulitis and present a systematic review to characterize its clinical presentation, diagnostic challenges and management. Clinical data for the index patient were retrospectively reviewed, and parental consent was obtained. A structured literature search was performed using PubMed, Scopus, and Embase. Studies reporting patients younger than 18 years were included. A 16-year-old male presented with right lower quadrant pain. CT suggested cecal diverticulitis. Worsening symptoms prompted diagnostic laparoscopy, revealing an inflamed diverticulum adjacent to a normal appendix. The postoperative course was uneventful. The review identified 27 studies including 101 patients. Median age was 14 years (IQR 12\u201316; range 3\u201317), with 57% male preponderance. Most cases involved a solitary right-sided diverticulum. CT correctly identified diverticulitis in 85%. Complicated disease occurred in 17%. In conclusion, in the pediatric age diverticulitis often arises from a solitary cecal diverticulum and can closely mimic appendicitis. Awareness may improve diagnosis, and uncomplicated cases can be treated conservatively with careful follow-up and appropriate clinical monitoring.<\/jats:p>","DOI":"10.1007\/s00383-026-06521-4","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:44:19Z","timestamp":1784547859000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric colonic diverticulitis: clinical presentation, management, and review of the literature"],"prefix":"10.1007","volume":"42","author":[{"given":"M.","family":"Pistone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bosisio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Wennemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tohmasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Zani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Zani-Ruttenstock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"issue":"4","key":"6521_CR1","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1055\/s-0044-1791282","volume":"38","author":"CJ Neylan","year":"2024","unstructured":"Neylan CJ, Kim A, Amy M, Hernandez PT (2024) The epidemiology of diverticulitis. Clin Colon Rectal Surg 38(4):241\u2013248. https:\/\/doi.org\/10.1055\/s-0044-1791282 PMID: 40501530; PMCID: PMC12151590","journal-title":"Clin Colon Rectal Surg"},{"issue":"5","key":"6521_CR2","doi-asserted-by":"publisher","first-page":"2195","DOI":"10.1016\/j.asjsur.2024.02.049","volume":"47","author":"JW Han","year":"2024","unstructured":"Han JW, Son J, Oh C (2024) Features of colonic diverticulitis in children and adolescents: a multicenter study. Asian J Surg 47(5):2195\u20132199. https:\/\/doi.org\/10.1016\/j.asjsur.2024.02.049 Epub 2024 Feb 22. PMID: 38388263","journal-title":"Asian J Surg"},{"issue":"3","key":"6521_CR3","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1007\/s10620-015-3925-0","volume":"61","author":"E Scaioli","year":"2016","unstructured":"Scaioli E, Colecchia A, Marasco G, Schiumerini R, Festi D (2016) Pathophysiology and therapeutic strategies for symptomatic uncomplicated diverticular disease of the colon. Dig Dis Sci 61(3):673\u2013683. https:\/\/doi.org\/10.1007\/s10620-015-3925-0 Epub 2015 Oct 12. PMID: 26458921","journal-title":"Dig Dis Sci"},{"issue":"12","key":"6521_CR4","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1111\/ped.14693","volume":"63","author":"T Hatakeyama","year":"2021","unstructured":"Hatakeyama T, Okata Y, Miyauchi H, Hisamatsu C, Nakatani T, Nakai Y, Bitoh Y (2021) Colonic diverticulitis in children: a retrospective study of 16 patients. Pediatr Int 63(12):1510\u20131513. https:\/\/doi.org\/10.1111\/ped.14693 Epub 2021 Oct 4. PMID: 33705582","journal-title":"PediatrInt"},{"key":"6521_CR5","doi-asserted-by":"publisher","unstructured":"Barlow B, Goodhue WW, Schullinger JN (1975) Giant congenital diverticulum of the sigmoid colon. J Pediatr Surg. 10(4):549\u2013550. https:\/\/doi.org\/10.1016\/0022-3468(75)90204-3","DOI":"10.1016\/0022-3468(75)90204-3"},{"issue":"6096","key":"6521_CR6","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1136\/bmj.2.6096.1194","volume":"2","author":"BI Rees","year":"1977","unstructured":"Rees BI, Griffin PJ (1977) Colonic diverticulosis in a child. Br Med J 2(6096):1194. https:\/\/doi.org\/10.1136\/bmj.2.6096.1194","journal-title":"Br Med J"},{"key":"6521_CR7","doi-asserted-by":"publisher","unstructured":"Halata MS, Newman LJ, Easton LB, Dove D, Stone RK (1983) Diverticulitis in an adolescent. Clin Pediatr (Phila). ;22(10):716-8. https:\/\/doi.org\/10.1177\/000992288302201007. PMID: 6617051","DOI":"10.1177\/000992288302201007"},{"key":"6521_CR8","doi-asserted-by":"publisher","unstructured":"Wilkinson S (1988) Acute solitary diverticulitis of the transverse colon in a child. Report of a case. Dis Colon Rectum 31(7):574-6. https:\/\/doi.org\/10.1007\/BF02553736","DOI":"10.1007\/BF02553736"},{"key":"6521_CR9","doi-asserted-by":"publisher","unstructured":"Benya EC, Nussbaum-Blask AR, Selby DM (1997) Colonic diverticulitis causing partial bowel obstruction in a child with cystic fibrosis. Pediatr Radiol 27(12):918-919. https:\/\/doi.org\/10.1007\/s002470050271","DOI":"10.1007\/s002470050271"},{"key":"6521_CR10","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1097\/01.MPG.0000155566.71902.3C","volume":"40","author":"KCE Sigaloff","year":"2005","unstructured":"Sigaloff KCE, van den Berg JG, Benninga MA (2005) Cecal diverticulitis in an adolescent. J Pediatr Gastroenterol Nutr 40:603\u2013605. https:\/\/doi.org\/10.1097\/01.MPG.0000155566.71902.3C","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"6521_CR11","doi-asserted-by":"publisher","unstructured":"Deshpande AV, Oliver M, Yin M, Goh TH, Hutson JM (2005) Severe colonic diverticulitis in an adolescent with Williams syndrome. J Paediatr Child Health 41(12):687\u2013688. https:\/\/doi.org\/10.1111\/j.1440-1754.2005.00761.x. PMID: 16398877","DOI":"10.1111\/j.1440-1754.2005.00761.x"},{"key":"6521_CR12","doi-asserted-by":"publisher","unstructured":"Garcia MA, Kling KM, Newbury RO, Huang JS (2009) Complicated diverticular disease in a child with williams syndrome. J Pediatr Gastroenterol Nut 48(2):233-236. https:\/\/doi.org\/10.1097\/MPG.0b013e31815c3b1b","DOI":"10.1097\/MPG.0b013e31815c3b1b"},{"issue":"10","key":"6521_CR13","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1007\/s00383-009-2472-1","volume":"25","author":"BJ Santin","year":"2009","unstructured":"Santin BJ, Prasad V, Caniano DA (2009) Colonic diverticulitis in adolescents: an index case and associated syndromes. Pediatr Surg Int 25(10):901\u2013905. https:\/\/doi.org\/10.1007\/s00383-009-2472-1","journal-title":"Pediatr Surg Int"},{"key":"6521_CR14","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s00383-011-3035-9","volume":"28","author":"E Cheng","year":"2012","unstructured":"Cheng E, Cohen L, Gasinu S, Sy C, Beneck D, Spigland N (2012) Cecal diverticulitis as a continuing diagnostic and management dilemma: a report of two cases in children. Pediatr Surg Int 28:99\u2013102","journal-title":"Pediatr Surg Int"},{"key":"6521_CR15","doi-asserted-by":"publisher","unstructured":"Ignacio RC Jr, Klapheke WP, Stephen T, Bond S (2012) Diverticulitis in a child with Williams syndrome: a case report and review of the literature. J Pediatr Surg 47(9):E33\u201335. https:\/\/doi.org\/10.1016\/j.jpedsurg.2012.05.036","DOI":"10.1016\/j.jpedsurg.2012.05.036"},{"issue":"1","key":"6521_CR16","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s00384-015-2171-4","volume":"31","author":"JT Huntington","year":"2016","unstructured":"Huntington JT, Brigode W, Thakkar RK, Raval MV, Teich S (2016) A case of pediatric cecal diverticulitis mimicking acute appendicitis. Int J Colorectal Dis 31(1):147\u2013148. https:\/\/doi.org\/10.1007\/s00384-015-2171-4","journal-title":"Int J Colorectal Dis"},{"key":"6521_CR17","doi-asserted-by":"publisher","unstructured":"Ho SY, Wu C, Liou CH, Fan HC (2016) Right-sided diverticulitis: an unusual presentation of abdominal pain in children. J Med Sci 36(3):123\u2013125 https:\/\/doi.org\/10.4103\/1011-4564.185218","DOI":"10.4103\/1011-4564.185218"},{"key":"6521_CR18","doi-asserted-by":"crossref","unstructured":"Horton JD, Black GE, Escobar MA (2017) Interval laparoscopic ileocecectomy in a child with cecal diverticulitis. J Pediatr Surg Case Rep 17:20\u201324","DOI":"10.1016\/j.epsc.2016.11.012"},{"key":"6521_CR19","doi-asserted-by":"publisher","unstructured":"Setlur A, Blaustein S (2018) An adult disease in an adolescent: rare presentation of diverticulitis with abscess. J Pediatric Surg Case Reps. 34:49\u201350, ISSN 2213\u20135766. https:\/\/doi.org\/10.1016\/j.epsc.2018.05.002","DOI":"10.1016\/j.epsc.2018.05.002"},{"issue":"4","key":"6521_CR20","doi-asserted-by":"publisher","first-page":"433","DOI":"10.14744\/SEMB.2017.76588","volume":"53","author":"ATB \u00c7il","year":"2019","unstructured":"\u00c7il ATB, G\u00fcm\u00fc\u015f S (2019) Solitary cecal diverticulitis mimicking acute appendicitis in a child: intraoperative diagnosis. Sisli Etfal Hastan Tip Bul 53(4):433\u2013436. https:\/\/doi.org\/10.14744\/SEMB.2017.76588 PMID: 32377122; PMCID: PMC7192303","journal-title":"Sisli Etfal Hastan Tip Bul"},{"key":"6521_CR21","doi-asserted-by":"publisher","unstructured":"Spacil K, Meyer J, Stehr M, Sch\u00e4fer M (2019) Laparoscopic repair of perforated cecal diverticulitis. J Pediatric Surg Case Rep 42:17\u201318. https:\/\/doi.org\/10.1016\/j.epsc.2018.12.006","DOI":"10.1016\/j.epsc.2018.12.006"},{"issue":"2","key":"6521_CR22","doi-asserted-by":"publisher","first-page":"e078","DOI":"10.1097\/PG9.0000000000000078","volume":"2","author":"M Bartel","year":"2021","unstructured":"Bartel M, Burnett C, Barnes D (2021) Sigmoid diverticulitis in an obese pediatric patient without genetic predisposition. JPGN Rep 2(2):e078. https:\/\/doi.org\/10.1097\/PG9.0000000000000078","journal-title":"JPGN Rep"},{"issue":"7","key":"6521_CR23","doi-asserted-by":"publisher","first-page":"e16649","DOI":"10.7759\/cureus.16649","volume":"13","author":"S Abuelazm","year":"2021","unstructured":"Abuelazm S, Kanumalla H, Taborda-Alvarez M, Eisdorfer J, Basak R (2021) Acute right-sided abdominal pain in an adolescent: expect the unexpected. Cureus 13(7):e16649. https:\/\/doi.org\/10.7759\/cureus.16649","journal-title":"Cureus"},{"key":"6521_CR24","doi-asserted-by":"publisher","first-page":"101929","DOI":"10.1016\/j.epsc.2021.101929","volume":"72","author":"ZW Lee","year":"2021","unstructured":"Lee ZW, Albright EA, Brown BP, Markel TA (2021) Congenital cecal diverticulitis in a pediatric patient. J Pediatr Surg Case Rep 72:101929. https:\/\/doi.org\/10.1016\/j.epsc.2021.101929 Epub 2021 Jun 2. PMID: 34422552; PMCID: PMC8372977","journal-title":"J Pediatr Surg Case Rep"},{"issue":"3","key":"6521_CR25","doi-asserted-by":"publisher","first-page":"249","DOI":"10.14744\/tjtes.2020.79357","volume":"28","author":"A\u0130 Anadolulu","year":"2022","unstructured":"Anadolulu A\u0130, Ger\u00e7el G, Kocaman OH (2022) Rare cecum pathologies as a cause of acute abdomen in children. Ulus Travma Acil Cerrahi Derg 28(3):249\u2013253. https:\/\/doi.org\/10.14744\/tjtes.2020.79357 PMID: 35485572; PMCID: PMC10493532","journal-title":"Ulus Travma Acil Cerrahi Derg"},{"issue":"1","key":"6521_CR26","doi-asserted-by":"publisher","first-page":"e77515","DOI":"10.7759\/cureus.77515","volume":"17","author":"T Fujii","year":"2025","unstructured":"Fujii T, Tanaka A, Katami H, Shimono R (2025) Right-sided colonic diverticulitis mimicking acute appendicitis in a pediatric patient: a case report. Cureus 17(1):e77515. https:\/\/doi.org\/10.7759\/cureus.77515","journal-title":"Cureus"},{"issue":"5","key":"6521_CR27","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.18621\/eurj.1668293","volume":"11","author":"H \u00d6zcan","year":"2025","unstructured":"\u00d6zcan H, \u00d6zer M, Kaya M (2025) A rare disease presenting with acute abdominal pain in a girl: solitary cecal diverticulum. Eur Res J 11(5):1023\u20131028. https:\/\/doi.org\/10.18621\/eurj.1668293","journal-title":"Eur Res J"},{"issue":"9","key":"6521_CR28","doi-asserted-by":"publisher","first-page":"rjaf721","DOI":"10.1093\/jscr\/rjaf721","volume":"2025","author":"HM Aziz","year":"2025","unstructured":"Aziz HM, Aljayyar MW, Qabbani H (2025) Complicated sigmoid diverticulitis in a 16-year-old patient in Saudi Arabia: a case report. J Surg Case Rep 2025(9):rjaf721. https:\/\/doi.org\/10.1093\/jscr\/rjaf721 PMID: 40917705; PMCID: PMC12413758","journal-title":"J Surg Case Rep"},{"key":"6521_CR29","doi-asserted-by":"publisher","first-page":"1478296","DOI":"10.3389\/fped.2024.1478296","volume":"12","author":"X Li","year":"2024","unstructured":"Li X, Liu W, Zhang S, Liu H (2024) Diagnosis and treatment experience of cecal diverticulitis in six pediatric patients. Front Pediatr 12:1478296. https:\/\/doi.org\/10.3389\/fped.2024.1478296 PMID: 39726533; PMCID: PMC11669651","journal-title":"Front Pediatr"},{"issue":"4","key":"6521_CR30","doi-asserted-by":"publisher","first-page":"196","DOI":"10.3393\/ac.2021.00192.0027","volume":"37","author":"GA Turner","year":"2021","unstructured":"Turner GA, O\u2019Grady MJ, Purcell RV, Frizelle FA (2021) The epidemiology and etiology of right-sided colonic diverticulosis: a review. Ann Coloproctol 37(4):196\u2013203. https:\/\/doi.org\/10.3393\/ac.2021.00192.0027","journal-title":"Ann Coloproctol"},{"issue":"3","key":"6521_CR31","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1111\/ans.12273","volume":"84","author":"KK Tan","year":"2014","unstructured":"Tan KK, Wong J, Yan Z, Chong CS, Liu JZ, Sim R (2014) Colonic diverticulitis in young Asians: a predominantly mild and right-sided disease. ANZ J Surg 84(3):181\u2013184. https:\/\/doi.org\/10.1111\/ans.12273","journal-title":"ANZ J Surg"},{"issue":"5","key":"6521_CR32","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1053\/j.gastro.2018.12.033","volume":"156","author":"LL Strate","year":"2019","unstructured":"Strate LL, Morris AM (2019) Epidemiology, Pathophysiology, and Treatment of Diverticulitis. Gastroenterology 156(5):1282\u20131298e1. https:\/\/doi.org\/10.1053\/j.gastro.2018.12.033","journal-title":"Gastroenterology"}],"container-title":["Pediatric Surgery International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-026-06521-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00383-026-06521-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00383-026-06521-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:03:35Z","timestamp":1784592215000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00383-026-06521-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,20]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["6521"],"URL":"https:\/\/doi.org\/10.1007\/s00383-026-06521-4","relation":{},"ISSN":["1437-9813"],"issn-type":[{"value":"1437-9813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,20]]},"assertion":[{"value":"10 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"315"}}