{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:58:49Z","timestamp":1761807529373},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2010,3,9]],"date-time":"2010-03-09T00:00:00Z","timestamp":1268092800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1007\/s00384-010-0914-9","type":"journal-article","created":{"date-parts":[[2010,3,8]],"date-time":"2010-03-08T07:25:13Z","timestamp":1268033113000},"page":"823-828","source":"Crossref","is-referenced-by-count":20,"title":["Clinicopathological features of colorectal cancer in patients under 40\u00a0years of age"],"prefix":"10.1007","volume":"25","author":[{"given":"Jyrki T.","family":"M\u00e4kel\u00e4","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heikki","family":"Kiviniemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,3,9]]},"reference":[{"key":"914_CR1","volume-title":"Finnish Cancer Registry\u2014Cancer incidence in Finland","author":"Institute for Statistical and Epidemiological Cancer Research","year":"2004","unstructured":"Institute for Statistical and Epidemiological Cancer Research (2004) Finnish Cancer Registry\u2014Cancer incidence in Finland. Institute for Statistical and Epidemiological Cancer Research, Helsinki"},{"key":"914_CR2","first-page":"105","volume":"183","author":"JC Cusack","year":"1996","unstructured":"Cusack JC, GiaccO CC, Cleary K, Davidson BS, Izzo F, Skibber J, Yen J, Curley SA (1996) Survival factors in 183 patients younger than 40\u00a0years old with colorectal adenocarcinoma. J Am Coll Surg 183:105\u2013112","journal-title":"J Am Coll Surg"},{"issue":"4","key":"914_CR3","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1002\/1097-0142(19880215)61:4<835::AID-CNCR2820610432>3.0.CO;2-X","volume":"61","author":"J Domerque","year":"1988","unstructured":"Domerque J, Ismail M, Astre C, Saint-Aubert J, Joyex H, Solassol C, Pujol H (1988) Colorectal carcinoma in patients younger than 40 ears of age. Montpellier cancer institute experience with 78 patients. Cancer 61(4):835\u2013840","journal-title":"Cancer"},{"key":"914_CR4","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/BF02554552","volume":"32","author":"C Smith","year":"1989","unstructured":"Smith C, Butler JA (1989) Colorectal cancer in patients younger than 40\u00a0years of age. Dis Colon Rectum 32:843\u2013846","journal-title":"Dis Colon Rectum"},{"key":"914_CR5","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/BF02050596","volume":"34","author":"ML Palmer","year":"1991","unstructured":"Palmer ML, Herrera L, Petrelli NJ (1991) Colorectal adenocarcinoma in patients less than 40\u00a0years of age. Dis Colon Rectum 34:322\u2013325","journal-title":"Dis Colon Rectum"},{"key":"914_CR6","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/BF02554121","volume":"29","author":"M Adloff","year":"1986","unstructured":"Adloff M, Arnaud JP, Schoegel M, Thibaud D, Bergamashi R (1986) Colorectal cancer in patients under 40\u00a0years of age. Dis Colon Rectum 29:322\u2013325","journal-title":"Dis Colon Rectum"},{"key":"914_CR7","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1007\/BF02237425","volume":"43","author":"F Paraf","year":"2000","unstructured":"Paraf F, Jothy S (2000) Colorectal cancer before the age of 40. Dis Colon Rectum 43:1222\u20131226","journal-title":"Dis Colon Rectum"},{"key":"914_CR8","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1046\/j.1365-2168.1998.00805.x","volume":"85","author":"YFA Chung","year":"1988","unstructured":"Chung YFA, MachinD EuK-W, Ho JMS, Nyam DCNK, Leong AFPK, Ho YH, Seow-Choen F (1988) Young age is not a poor prognostic marker in colorectal cancer. Br J Surg 85:1255\u20131259","journal-title":"Br J Surg"},{"key":"914_CR9","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/00000658-196709000-00010","volume":"166","author":"RB Turnbull","year":"1967","unstructured":"Turnbull RB, Kyle K, Watson FR, Spratt J (1967) Cancer of the colon, the influence of non-touch isolation technic on survival rates. Ann Surg 166:420\u2013427","journal-title":"Ann Surg"},{"key":"914_CR10","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-83693-0","volume-title":"Histologic typing of intestinal tumours. World Health Organisation. International classification of tumours","author":"JR Jass","year":"1989","unstructured":"Jass JR, Sobin LH (1989) Histologic typing of intestinal tumours. World Health Organisation. International classification of tumours, 2nd edn. Springer, Heidelberg","edition":"2"},{"key":"914_CR11","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1001\/archsurg.1995.01430100040009","volume":"130","author":"JT M\u00e4kel\u00e4","year":"1995","unstructured":"M\u00e4kel\u00e4 JT, Laitinen ST, Kairaluoma MI (1995) Five-year follow-up after radical surgery for colorectal cancer. Arch Surg 130:1062\u20131067","journal-title":"Arch Surg"},{"key":"914_CR12","first-page":"1505","volume":"92","author":"R Fante","year":"1997","unstructured":"Fante R, Benatti P, di Gregorio C, De Pietri S, Pedroni M, Tamassia MG, Percesepe A, Rossi G, Losi L, Roncucci L, Ponz de Leon M (1997) Colorectal carcinoma in different age group: a population based investigation. Am J Gastroenterol 92:1505\u20131509","journal-title":"Am J Gastroenterol"},{"key":"914_CR13","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1080\/00365521.1984.12005784","volume":"19","author":"HJ J\u00e4rvinen","year":"1984","unstructured":"J\u00e4rvinen HJ, Turunen MJ (1984) Colorectal cancer before 40\u00a0years of age: prognosis and predisposing conditions. Scand J Gastroenterol 19:634\u2013838","journal-title":"Scand J Gastroenterol"},{"key":"914_CR14","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.amjsurg.2003.12.020","volume":"187","author":"JB O\u2019Connell","year":"2003","unstructured":"O\u2019Connell JB, Maggard MA, Livingston EH, Yo CK (2003) Colorectal cancer in the young. Am J Surg 187:343\u2013348","journal-title":"Am J Surg"},{"key":"914_CR15","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1056\/NEJM199412223312501","volume":"331","author":"CS Fuchs","year":"1994","unstructured":"Fuchs CS, Giovannuchi EL, Colditz GA, Hunter DJ, Speizer FE, Willett WC (1994) NEJM 331:1669\u20131674","journal-title":"NEJM"},{"key":"914_CR16","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1007\/BF02054690","volume":"39","author":"JG Guillem","year":"1996","unstructured":"Guillem JG, Bastar AL, Ng J, Huhn JL, Cohen AM (1996) Clustering of colorectal cancer in families of probands under 40\u00a0years of age. Dis Colon Rectum 39:1004\u20131007","journal-title":"Dis Colon Rectum"},{"key":"914_CR17","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/BF02234737","volume":"44","author":"E Mitry","year":"2001","unstructured":"Mitry E, Benhamiche A-M, Jouve J-L, Clinard F, Finn-Faivre C, Faivre J (2001) Colorectal adenocarcinoma in patients under 45\u00a0years of age: comparison with older patients in a well-defined French population. Dis Colon Rectum 44:380\u2013387","journal-title":"Dis Colon Rectum"},{"key":"914_CR18","first-page":"1505","volume":"92","author":"R Fante","year":"1997","unstructured":"Fante R, Benatti P, di Gregorio C, De Pietri S, Pedroni M, Tamassia MG, Percesepe A, Rossi G, Losi L, Roncucci L (1997) Ponz de Leon M. Am J Gastroenterol 92:1505\u20131509","journal-title":"Am J Gastroenterol"},{"key":"914_CR19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF02055674","volume":"40","author":"EL Bokey","year":"1997","unstructured":"Bokey EL, Chapuis PH, Dent OF, Newland RC, Koorey SG, Zelas PJ, Etewart PJ (1997) Factors affecting survival after excision of the rectum for cancer. Dis Colon Rectum 40:3\u201310","journal-title":"Dis Colon Rectum"},{"key":"914_CR20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/bjs.4015","volume":"90","author":"JT Liang","year":"2002","unstructured":"Liang JT, Huang KC, Cheng AL, Wu JYM, MS WSM (2002) Clinicopathological and molecular biological features of colorectal cancer in patients less than 40\u00a0years of age. Br J Surg 90:205\u2013214","journal-title":"Br J Surg"},{"key":"914_CR21","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s10350-006-0650-y","volume":"49","author":"A King-Yin Lam","year":"2006","unstructured":"King-Yin Lam A, Ong K, Ho YH (2006) Coloretal mucinous adenocarcinoma: the clinicopathological features and significance of p16 and p53 expression. Dis Colon Rectum 49:1275\u20131283","journal-title":"Dis Colon Rectum"},{"key":"914_CR22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF02586840","volume":"23","author":"S Bulow","year":"1980","unstructured":"Bulow S (1980) Colorectal cancer in patients less than 40\u00a0years of age in Denmark, 1943\u20131956. Dis Colon Rectum 23:327\u2013336","journal-title":"Dis Colon Rectum"},{"key":"914_CR23","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0016-5085(88)90427-1","volume":"94","author":"S Grossman","year":"1988","unstructured":"Grossman S, Milos ML (1988) Colonoscopic screening of persons with suspected risk factors for colon cancer: I family history. Gastroenterology 94:395\u2013400","journal-title":"Gastroenterology"},{"key":"914_CR24","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1007\/s00384-005-0058-5","volume":"21","author":"M Menges","year":"2006","unstructured":"Menges M, G\u00e4rtner B, Georg T, Fischinger J, Zeitz M (2006) Cost-benefit analysis of screening colonoscopy in 40-to 50-year old first-degree relatives of patients with colorectal cancer. Int J Colorectal Dis 21:596\u2013601","journal-title":"Int J Colorectal Dis"},{"key":"914_CR25","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/BF02156258","volume":"33","author":"WH Isbister","year":"1990","unstructured":"Isbister WH, Fraser J (1990) Large bowel cancer in the young: a national survey study. Dis Colon Rectum 33:363\u2013366","journal-title":"Dis Colon Rectum"},{"key":"914_CR26","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1056\/NEJMoa0808268","volume":"360","author":"TJ Koopman","year":"2009","unstructured":"Koopman TJ, Cats A, Rodenburg CA, Creemers GJ, Scharma JG, Erdkamp FL, Vos AH, van Groeningen CJ, Sinnige HA, Richel DJ, Voest EE, Dijktra JR, Vink-B\u00f6rger ME, Antonini NF, Mol L, van Krieken JH, Dalesio O, Punt CJ (2009) Chemotherapy, bevacitzumab, and cetuximab in metastatic colorecla cancer. N Engl J Med 360:563\u2013572","journal-title":"N Engl J Med"},{"key":"914_CR27","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1093\/annonc\/mdi244","volume":"16","author":"FV Negri","year":"2005","unstructured":"Negri FV, Wotherspoon A, Cunningham D, Norman AR, Chong G, Ross PJ (2005) Mucinous histology predicts for reduced fluorouracil responsiveness and survival in advanced colorectal cancer. Ann Oncol 16:1305\u20131310","journal-title":"Ann Oncol"},{"key":"914_CR28","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/sj.bjc.6604955","volume":"100","author":"V Catalano","year":"2009","unstructured":"Catalano V, Loupakis F, Graziano F, Torresi U, Bisonni R, Mari D, Fornaro L, Baldelli AM, Giordani P, Rossi D, Alessadroni P, Giustini L, Silva RR, Falcone A, D\u2019Emidio S, Fedeli SL (2009) Mucous histology predicts for poor response related overall survival of patients with colorectal cancer and treated with first-line oxaliplatin-and\/or irinotecan-based chemotherapy. Br J Cancer 100:881\u2013887","journal-title":"Br J Cancer"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-010-0914-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00384-010-0914-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-010-0914-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T12:05:30Z","timestamp":1559045130000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00384-010-0914-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,9]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["914"],"URL":"https:\/\/doi.org\/10.1007\/s00384-010-0914-9","relation":{},"ISSN":["0179-1958","1432-1262"],"issn-type":[{"value":"0179-1958","type":"print"},{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,9]]}}}