{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:12:35Z","timestamp":1788952355034,"version":"build-2803163510"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T00:00:00Z","timestamp":1387324800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1007\/s00384-013-1807-5","type":"journal-article","created":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T02:17:16Z","timestamp":1387246636000},"page":"387-393","source":"Crossref","is-referenced-by-count":50,"title":["Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis\u2014a prospective randomized study"],"prefix":"10.1007","volume":"29","author":[{"given":"Lukasz","family":"Krokowicz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran","family":"Stojcev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bartosz Filip","family":"Kaczmarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Kociemba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u017cbieta","family":"Kaczmarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslaw","family":"Walkowiak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Krokowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Drews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Banasiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,18]]},"reference":[{"key":"1807_CR1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0300-5089(21)00097-3","volume":"4","author":"TG Parks","year":"1975","unstructured":"Parks TG (1975) Natural history of diverticular disease of the colon. Clin Gastroenterol 4:3\u201321","journal-title":"Clin Gastroenterol"},{"key":"1807_CR2","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1097\/01.mcg.0000124003.07433.ee","volume":"38","author":"MH Floch","year":"2004","unstructured":"Floch MH, Bina I (2004) The natural history of diverticulitis: fact and theory. J Clin Gastroenterol 38:S2\u2013S7","journal-title":"J Clin Gastroenterol"},{"key":"1807_CR3","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/BF02049475","volume":"39","author":"KD Munson","year":"1996","unstructured":"Munson KD, Hensien MA, Jacob LN, Robinson AM, Liston WA (1996) Diverticulitis: a comprehensive follow-up. Dis Colon Rectum 39:318\u2013324","journal-title":"Dis Colon Rectum"},{"key":"1807_CR4","doi-asserted-by":"crossref","unstructured":"World Medical Association (2008) WMA Declaration of Helsinki\u2014ethical principles for medical research involving human subjects, Seoul, Korea","DOI":"10.1515\/9783110208856.233"},{"key":"1807_CR5","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1365-2036.2005.02422.x","volume":"21","author":"A Mizuki","year":"2005","unstructured":"Mizuki A, Nagata H, Tatemichi M, Kaneda S, Tsukada N, Ishii H, Hibi T (2005) The out-patient management of patients with acute mild-to-moderate colonic diverticulitis. Aliment Pharmacol Ther 21:889\u2013897","journal-title":"Aliment Pharmacol Ther"},{"issue":"10","key":"1807_CR6","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1007\/BF02236631","volume":"43","author":"P Ambrosetti","year":"2000","unstructured":"Ambrosetti P, Jenny A, Becker C, Terrier TF, Morel P (2000) Acute left colonic diverticulitis\u2014compared performance of computed tomography and water-soluble contrast enema: prospective evaluation of 420 patients. Dis Colon Rectum 43(10):1363\u20131367","journal-title":"Dis Colon Rectum"},{"key":"1807_CR7","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/SLA.0b013e3181952888","volume":"249","author":"DA Etzioni","year":"2009","unstructured":"Etzioni DA, Mack TM, Beart RW Jr, Kaiser AM (2009) Diverticulitis in the United States: 1998\u20132005: changing patterns of disease and treatment. Ann Surg 249:210\u2013217","journal-title":"Ann Surg"},{"key":"1807_CR8","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/bjs.1800711202","volume":"71","author":"ZH Krukowski","year":"1984","unstructured":"Krukowski ZH, Matheson NA (1984) Emergency surgery for diverticular disease complicated by generalized and faecal peritonitis: a review. Br J Surg 71:921\u2013927","journal-title":"Br J Surg"},{"key":"1807_CR9","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/BF02258291","volume":"43","author":"WD Wong","year":"2000","unstructured":"Wong WD, Wexner SD, Lowry A, Vernava A III, Burnstein M (2000) Practice parameters for the treatment of sigmoid diverticulitis\u2014supporting documentation. The Standards Task Force. The American Society of Colon and Rectal Surgeons. Dis Colon Rectum 43:290\u2013297","journal-title":"Dis Colon Rectum"},{"key":"1807_CR10","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1136\/bmj.4.5684.639","volume":"4","author":"TG Parks","year":"1969","unstructured":"Parks TG (1969) Natural history of diverticular disease of the colon. A review of 521 cases. Br Med J 4:639\u2013642","journal-title":"Br Med J"},{"key":"1807_CR11","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1111\/j.1440-1746.2007.05118.x","volume":"22","author":"G Peppas","year":"2007","unstructured":"Peppas G, Bliziotis LA, Oikonomaki D, Falagas ME (2007) Outcomes after medical and surgical treatment of diverticulitis: a systematic review of the available evidence. J Gastroenterol Hepatol 22:1360\u20131368","journal-title":"J Gastroenterol Hepatol"},{"key":"1807_CR12","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/S0140-6736(77)92112-2","volume":"1","author":"AJ Brodribb","year":"1977","unstructured":"Brodribb AJ (1977) Treatment of symptomatic diverticular disease with a high-fibre diet. Lancet 1:664\u2013666","journal-title":"Lancet"},{"key":"1807_CR13","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1136\/bmj.282.6273.1353","volume":"282","author":"MH Ornstein","year":"1981","unstructured":"Ornstein MH, Littlewood ER, Baird IM, Fowler J, North WR, Cox AG (1981) Are fibre supplements really necessary in diverticular disease of the colon? A controlled clinical trial. Br Med J (Clin Res Ed) 282:1353\u20131356","journal-title":"Br Med J (Clin Res Ed)"},{"key":"1807_CR14","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0002-9343(98)00343-X","volume":"106","author":"JR Lupton","year":"1999","unstructured":"Lupton JR, Turner ND (1999) Potential protective mechanisms of wheat bran fiber. Am J Med 106:24\u201327","journal-title":"Am J Med"},{"key":"1807_CR15","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.3748\/wjg.v13.i31.4161","volume":"13","author":"KY Tan","year":"2007","unstructured":"Tan KY, Seow-Choen F (2007) Fiber and colorectal diseases: separating fact from fiction. World J Gastroenterol 13:4161\u20134167","journal-title":"World J Gastroenterol"},{"key":"1807_CR16","unstructured":"Gronek P, Holdys J. (2013) Genes and physical fitness. Trends in Sport Sciences 20(1):16\u201329."},{"key":"1807_CR17","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S1590-8658(02)80110-4","volume":"34","author":"A Tursi","year":"2002","unstructured":"Tursi A, Brandimarte G, Daffin\u00e0 R (2002) Long-term treatment with mesalazine and rifaximin versus rifaximin alone for patients with recurrent attacks of acute diverticulitis of colon. Dig Liver Dis 34:510\u2013515","journal-title":"Dig Liver Dis"},{"key":"1807_CR18","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3748\/wjg.v13.i2.264","volume":"13","author":"A Colecchia","year":"2007","unstructured":"Colecchia A, Vestito A, Pasqui F, Mazzella G, Roda E, Pistoia F (2007) Efficacy of long term cyclic administration of the poorly absorbed antibiotic rifaximin in symptomatic, uncomplicated colonic diverticular disease. World J Gastroenterol 13:264\u2013269","journal-title":"World J Gastroenterol"},{"key":"1807_CR19","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1097\/00042737-200303000-00015","volume":"15","author":"P Fric","year":"2003","unstructured":"Fric P, Zavoral M (2003) The effect of non-pathogenic Escherichia coli in symptomatic uncomplicated diverticular disease of the colon. Eur J Gastroenterol Hepatol 15:313\u2013315","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"1807_CR20","first-page":"29","volume":"15","author":"S Giaccari","year":"1993","unstructured":"Giaccari S, Tronci S, Falconieri M, Ferrieri A (1993) Long-term treatment with rifaximin and lactobacilli in post-diverticulitic stenoses of the colon. Riv Eur Sci Med Farmacol 15:29\u201334","journal-title":"Riv Eur Sci Med Farmacol"},{"key":"1807_CR21","first-page":"31","volume":"19","author":"P Lamiki","year":"2010","unstructured":"Lamiki P, Tsuchiya J, Pathak S, Okura R, Solimene U, Jain S (2010) Probiotics in diverticular disease of the colon: an open label study. J Gastrointestin Liver Dis 19:31\u201336","journal-title":"J Gastrointestin Liver Dis"},{"key":"1807_CR22","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1463-1318.2012.03152.x","volume":"15","author":"T Banasiewicz","year":"2013","unstructured":"Banasiewicz T, Krokowicz L, Stojcev Z, Kaczmarek BF, Kaczmarek E, Maik J, Marciniak R, Krokowicz P, Walkowiak J, Drews M (2013) Microencapsulated sodium butyrate reduces the frequency of abdominal pain in patients with irritable bowel syndrome. Colorectal Dis 15:204\u2013209","journal-title":"Colorectal Dis."},{"key":"1807_CR23","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1002\/(SICI)1097-0215(19981209)78:6<735::AID-IJC11>3.0.CO;2-6","volume":"78","author":"S Cordel","year":"1998","unstructured":"Cordel S, Dupas B, Douillard JY, Meflah K (1998) Interleukin-2\/sodium butyrate treatment cures rats bearing liver tumors after acquired 5-fluorouracil resistance. Int J Cancer 78:735\u2013739","journal-title":"Int J Cancer"},{"key":"1807_CR24","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/DCR.0b013e3182028576","volume":"54","author":"JF Hall","year":"2011","unstructured":"Hall JF, Roberts PL, Ricciardi R (2011) Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence? Dis Colon Rectum 54:283\u2013288","journal-title":"Dis Colon Rectum"},{"key":"1807_CR25","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1046\/j.1365-2362.2003.01130.x","volume":"33","author":"P Vernia","year":"2003","unstructured":"Vernia P, Annese V, Bresci G, d'Albasio G, D'Inc\u00e0 R, Giaccari S (2003) Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial. Eur J Clin Investig 33:244\u2013248","journal-title":"Eur J Clin Investig"},{"key":"1807_CR26","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1365-2036.2007.03562.x","volume":"27","author":"HM Hamer","year":"2008","unstructured":"Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ, Brummer RJ (2008) Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther 27:104\u2013119","journal-title":"Aliment Pharmacol Ther"},{"key":"1807_CR27","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1152\/physrev.2001.81.3.1031","volume":"81","author":"DL Topping","year":"2001","unstructured":"Topping DL, Clifton PM (2001) Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev 81:1031\u20131064","journal-title":"Physiol Rev"},{"key":"1807_CR28","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1053\/j.gastro.2004.03.071","volume":"127","author":"RB Canani","year":"2004","unstructured":"Canani RB, Terrin G, Cirillo P, Castaldo G, Salvatore F, Cardillo G, Coruzzo A, Troncone R (2004) Butyrate as an effective treatment of congenital chloride diarrhea. Gastroenterology 127:630\u2013634","journal-title":"Gastroenterology"},{"key":"1807_CR29","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0016-5085(76)80011-X","volume":"70","author":"MG Schmitt Jr","year":"1976","unstructured":"Schmitt MG Jr, Soergel KH, Wood CM (1976) Absorption of short chain fatty acids from the human jejunum. Gastroenterology 70:211\u2013215","journal-title":"Gastroenterology"},{"key":"1807_CR30","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1136\/gut.2003.018093","volume":"53","author":"CH Clemens","year":"2004","unstructured":"Clemens CH, Samsom M, Roelofs J, van Berge Henegouwen GP, Smout AJ (2004) Colorectal visceral perception in diverticular disease. Gut 53:717\u2013722","journal-title":"Gut"},{"key":"1807_CR31","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1111\/j.1365-2036.2006.02896.x","volume":"23","author":"L Petruzziello","year":"2006","unstructured":"Petruzziello L, Iacopini F, Bulajic M, Shah S, Costamanga G (2006) Review article: uncomplicated diverticular disease of the colon. Aliment Pharmacol Ther 23:1379\u20131391","journal-title":"Aliment Pharmacol Ther"},{"key":"1807_CR32","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.3748\/wjg.v13.i7.1079","volume":"13","author":"A Roda","year":"2007","unstructured":"Roda A, Simoni P, Magliulo M, Nanni P, Baraldini M, Roda G, Roda E (2007) A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon. World J Gastroenterol 13:1079\u20131084","journal-title":"World J Gastroenterol"},{"key":"1807_CR33","first-page":"295","volume":"19","author":"A Zullo","year":"2010","unstructured":"Zullo A, Hassan C, Maconi G, Manes G, Tammaro G, De Francesco V, Annibale B, Ficano L, Buri L, Gatto G, Lorenzetti R, Campo SM, Ierardi E, Pace F, Morini S (2010) Cyclic antibiotic therapy for diverticular disease: a critical reappraisal. J Gastrointestin Liver Dis 19:295\u2013302","journal-title":"J Gastrointestin Liver Dis."},{"key":"1807_CR34","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1572-0241.2003.07158.x","volume":"98","author":"CJ Bijkerk","year":"2003","unstructured":"Bijkerk CJ, de Wit NJ, Muris JW, Jones RH, Knottnerus JA, Hoes AW (2003) Outcome measures in irritable bowel syndrome: comparison of psychometric and methodological characteristics. Am J Gastroenterol 98:122\u2013127","journal-title":"Am J Gastroenterol"},{"key":"1807_CR35","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1053\/j.gastro.2005.11.058","volume":"130","author":"EJ IIrvine","year":"2006","unstructured":"IIrvine EJ, Whitehead WE, Chey WD, Matsueda K, Shaw M, Talley NJ et al (2006) Design of treatment trials for functional gastrointestinal disorders. Gastroenterology 130:1538\u20131551","journal-title":"Gastroenterology"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00384-013-1807-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-013-1807-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-013-1807-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T22:09:12Z","timestamp":1647727752000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00384-013-1807-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,18]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["1807"],"URL":"https:\/\/doi.org\/10.1007\/s00384-013-1807-5","relation":{},"ISSN":["0179-1958","1432-1262"],"issn-type":[{"value":"0179-1958","type":"print"},{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,18]]}}}