{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T20:42:39Z","timestamp":1776372159324,"version":"3.51.2"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2016,9,21]],"date-time":"2016-09-21T00:00:00Z","timestamp":1474416000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s00384-016-2640-4","type":"journal-article","created":{"date-parts":[[2016,9,21]],"date-time":"2016-09-21T07:18:20Z","timestamp":1474442300000},"page":"1845-1852","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Association between pathologic features of peripheral nerves and postoperative anal function after neoadjuvant therapy for low rectal cancer"],"prefix":"10.1007","volume":"31","author":[{"given":"Keinchi","family":"Koushi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Nishizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motohiro","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuichi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Ochiai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,9,21]]},"reference":[{"key":"2640_CR1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00000658-199404000-00007","volume":"219","author":"PB Paty","year":"1994","unstructured":"Paty PB, Enker WE, Cohen AM, Lauwers GY (1994) Treatment of rectal cancer by low anterior resection with coloanal anastomosis. Ann Surg 219:365\u2013373","journal-title":"Ann Surg"},{"key":"2640_CR2","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1002\/bjs.1800810944","volume":"81","author":"R Schiessel","year":"1994","unstructured":"Schiessel R, Karner-Hanusch J, Herbst F, Teleky B, Wunderlich M (1994) Intersphincteric resection for low rectal tumours. Br J Surg 81:1376\u20131378","journal-title":"Br J Surg"},{"key":"2640_CR3","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.1007\/s00268-009-0079-2","volume":"33","author":"N Saito","year":"2009","unstructured":"Saito N, Sugito M, Ito M, Kobayashi A, Nishizawa Y, Yoneyama Y, Nishizawa Y, Minagawa N (2009) Oncologic outcome of intersphincteric resection for very low rectal cancer. World J Surg 33:1750\u20131756. doi: 10.1007\/s00268-009-0079-2","journal-title":"World J Surg"},{"key":"2640_CR4","doi-asserted-by":"crossref","unstructured":"Gamagami RA, Liagre A, Chiotasso P, Istvan G, Lazorthes F (1999) Coloanal anastomosis for distal third rectal cancer: prospective study of oncologic results. Dis Colon rectum 42:1272\u20131275","DOI":"10.1007\/BF02234212"},{"key":"2640_CR5","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1111\/j.1463-1318.2005.00839.x","volume":"8","author":"W Hohenberger","year":"2006","unstructured":"Hohenberger W, Merkel S, Matzel K, Bittorf B, Papadopoulos T, Gohl J (2006) The influence of abdomino-peranal (intersphincteric) resection of lower third rectal carcinoma on the rates of sphincter preservation and locoregional recurrence. Color Dis 8:23\u201333. doi: 10.1111\/j.1463-1318.2005.00839.x","journal-title":"Color Dis"},{"key":"2640_CR6","doi-asserted-by":"crossref","unstructured":"Bonadeo FA, Vaccaro CA, Benati ML, Quintana GM, Garione XE, Telenta MT (2001) Rectal cancer: local recurrence after surgery without radiotherapy. Dis Colon rectum 44:374\u2013379","DOI":"10.1007\/BF02234736"},{"key":"2640_CR7","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/01.sla.0000154551.06768.e1","volume":"241","author":"E Rullier","year":"2005","unstructured":"Rullier E, Laurent C, Bretagnol F, Rullier A, Vendrely V, Zerbib F (2005) Sphincter-saving resection for all rectal carcinomas: the end of the 2-cm distal rule. Ann Surg 241:465\u2013469","journal-title":"Ann Surg"},{"key":"2640_CR8","doi-asserted-by":"crossref","unstructured":"Rullier E, Zerbib F, Laurent C, Bonnel C, Caudry M, Saric J, Parneix M (1999) Intersphincteric resection with excision of internal anal sphincter for conservative treatment of very low rectal cancer. Dis Colon rectum 42:1168\u20131175","DOI":"10.1007\/BF02238569"},{"key":"2640_CR9","doi-asserted-by":"publisher","unstructured":"Saito N, Ono M, Sugito M, Ito M, Morihiro M, Kosugi C, Sato K, Kotaka M, Nomura S, Arai M, Kobatake T (2004) Early results of intersphincteric resection for patients with very low rectal cancer: an active approach to avoid a permanent colostomy. Dis Colon rectum 47:459\u2013466. doi: 10.1007\/s10350-003-0088-4","DOI":"10.1007\/s10350-003-0088-4"},{"key":"2640_CR10","doi-asserted-by":"crossref","unstructured":"Kohler A, Athanasiadis S, Ommer A, Psarakis E (2000) Long-term results of low anterior resection with intersphincteric anastomosis in carcinoma of the lower one-third of the rectum: analysis of 31 patients. Dis Colon rectum 43:843\u2013850","DOI":"10.1007\/BF02238025"},{"key":"2640_CR11","doi-asserted-by":"publisher","unstructured":"Ito M, Saito N, Sugito M, Kobayashi A, Nishizawa Y, Tsunoda Y (2009) Analysis of clinical factors associated with anal function after intersphincteric resection for very low rectal cancer. Dis Colon rectum 52:64\u201370. doi: 10.1007\/DCR.0b013e31819739a0","DOI":"10.1007\/DCR.0b013e31819739a0"},{"key":"2640_CR12","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1097\/SLA.0b013e31815c29ff","volume":"246","author":"R Chamlou","year":"2007","unstructured":"Chamlou R, Parc Y, Simon T, Bennis M, Dehni N, Parc R, Tiret E (2007) Long-term results of intersphincteric resection for low rectal cancer. Ann Surg 246:916\u2013921. doi: 10.1097\/SLA.0b013e31815c29ff","journal-title":"Ann Surg"},{"key":"2640_CR13","doi-asserted-by":"publisher","unstructured":"Lim JF, Tang CL, Seow-Choen F, Heah SM (2005) Prospective, randomized trial comparing intraoperative colonic irrigation with manual decompression only for obstructed left-sided colorectal cancer. Dis Colon rectum 48:205\u2013209. doi: 10.1007\/s10350-004-0803-9","DOI":"10.1007\/s10350-004-0803-9"},{"key":"2640_CR14","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/j.1445-2197.1995.tb00547.x","volume":"65","author":"FC Chen","year":"1995","unstructured":"Chen FC, Mackay JR, Woods RJ, Collopy BT, Fink RJ, Guiney MJ (1995) Early experience with postoperative adjuvant chemoradiation for rectal carcinoma: focus on morbidity. Aust N Z J Surg 65:732\u2013736","journal-title":"Aust N Z J Surg"},{"key":"2640_CR15","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1097\/00000658-199411000-00012","volume":"220","author":"CF Kollmorgen","year":"1994","unstructured":"Kollmorgen CF, Meagher AP, Wolff BG, Pemberton JH, Martenson JA, Illstrup DM (1994) The long-term effect of adjuvant postoperative chemoradiotherapy for rectal carcinoma on bowel function. Ann Surg 220:676\u2013682","journal-title":"Ann Surg"},{"key":"2640_CR16","doi-asserted-by":"publisher","unstructured":"Da Silva GM, Berho M, Wexner SD, Efron J, Weiss EG, Nogueras JJ, Vernava AM III, Connor JT, Gervaz P (2003) Histologic analysis of the irradiated anal sphincter. Dis Colon rectum 46:1492\u20131497. doi: 10.1097\/01.dcr.0000093642.89267.67","DOI":"10.1097\/01.dcr.0000093642.89267.67"},{"key":"2640_CR17","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/s0140-6736(08)60455-9","volume":"371","author":"B Nordlinger","year":"2008","unstructured":"Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P, Bechstein WO, Primrose JN, Walpole ET, Finch-Jones M, Jaeck D, Mirza D, Parks RW, Collette L, Praet M, Bethe U, Van Cutsem E, Scheithauer W, Gruenberger T (2008) Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC intergroup trial 40983): a randomised controlled trial. Lancet 371:1007\u20131016. doi: 10.1016\/s0140-6736(08)60455-9","journal-title":"Lancet"},{"key":"2640_CR18","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1093\/annonc\/mdn370","volume":"19","author":"ML Rothenberg","year":"2008","unstructured":"Rothenberg ML, Cox JV, Butts C, Navarro M, Bang YJ, Goel R, Gollins S, Siu LL, Laguerre S, Cunningham D (2008) Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil\/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study. Ann Oncol 19:1720\u20131726. doi: 10.1093\/annonc\/mdn370","journal-title":"Ann Oncol"},{"key":"2640_CR19","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1200\/jco.2005.04.4875","volume":"24","author":"I Chau","year":"2006","unstructured":"Chau I, Brown G, Cunningham D, Tait D, Wotherspoon A, Norman AR, Tebbutt N, Hill M, Ross PJ, Massey A, Oates J (2006) Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer. J Clin Oncol 24:668\u2013674. doi: 10.1200\/jco.2005.04.4875","journal-title":"J Clin Oncol"},{"key":"2640_CR20","doi-asserted-by":"publisher","unstructured":"Nishizawa Y, Fujii S, Saito N, Ito M, Ochiai A, Sugito M, Kobayashi A, Nishizawa Y (2011) The association between anal function and neural degeneration after preoperative chemoradiotherapy followed by intersphincteric resection. Dis Colon rectum 54:1423\u20131429. doi: 10.1097\/DCR.0b013e31822c94e6","DOI":"10.1097\/DCR.0b013e31822c94e6"},{"key":"2640_CR21","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s003840050072","volume":"12","author":"O Dworak","year":"1997","unstructured":"Dworak O, Keilholz L, Hoffmann A (1997) Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Color Dis 12:19\u201323","journal-title":"Int J Color Dis"},{"key":"2640_CR22","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/j.ijrobp.2004.11.017","volume":"62","author":"FM Vecchio","year":"2005","unstructured":"Vecchio FM, Valentini V, Minsky BD, Padula GD, Venkatraman ES, Balducci M, Micciche F, Ricci R, Morganti AG, Gambacorta MA, Maurizi F, Coco C (2005) The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer. Int J Radiat Oncol Biol Phys 62:752\u2013760. doi: 10.1016\/j.ijrobp.2004.11.017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2640_CR23","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/sj.bjc.6600467","volume":"87","author":"SL Cheeseman","year":"2002","unstructured":"Cheeseman SL, Joel SP, Chester JD, Wilson G, Dent JT, Richards FJ, Seymour MT (2002) A \u2018modified de Gramont\u2019 regimen of fluorouracil, alone and with oxaliplatin, for advanced colorectal cancer. Br J Cancer 87:393\u2013399. doi: 10.1038\/sj.bjc.6600467","journal-title":"Br J Cancer"},{"key":"2640_CR24","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1007\/s00384-012-1434-6","volume":"27","author":"Y Nishizawa","year":"2012","unstructured":"Nishizawa Y, Fujii S, Saito N, Ito M, Nakajima K, Ochiai A, Sugito M, Kobayashi A, Nishizawa Y (2012) Differences in tissue degeneration between preoperative chemotherapy and preoperative chemoradiotherapy for colorectal cancer. Int J Colorect Dis 27:1047\u20131053. doi: 10.1007\/s00384-012-1434-6","journal-title":"Int J Colorect Dis"},{"issue":"Suppl 1","key":"2640_CR25","doi-asserted-by":"crossref","first-page":"S152","DOI":"10.1007\/s12032-010-9658-1","volume":"28","author":"NW Choong","year":"2011","unstructured":"Choong NW, Mauer AM, Haraf DC, Ferguson MK, Sandler AB, Kesler KA, Fishkin PA, Ansari RH, Wade J III, Krauss SA, Sciortino DF, Posner MC, Kocherginsky M, Hoffman PC, Szeto L, Vokes EE (2011) Long-term outcome of a phase II study of docetaxel-based multimodality chemoradiotherapy for locally advanced carcinoma of the esophagus or gastroesophageal junction. Med Oncol 28(Suppl 1):S152\u2013S161","journal-title":"Med Oncol"},{"key":"2640_CR26","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/jjco\/hyi241","volume":"36","author":"T Shimoda","year":"2006","unstructured":"Shimoda T, Koizumi W, Tanabe S, Higuchi K, Sasaki T, Nakayama N, Azuma M, Saigenji K, Katou T, Ogino M (2006) Small-cell carcinoma of the esophagus associated with a paraneoplastic neurological syndrome: a case report documenting a complete response. Jpn J Clin Oncol 36:109\u2013112","journal-title":"Jpn J Clin Oncol"},{"key":"2640_CR27","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.ijrobp.2007.04.008","volume":"69","author":"Y Nishimura","year":"2007","unstructured":"Nishimura Y, Nakagawa K, Takeda K, Tanaka M, Segawa Y, Tsujino K, Negoro S, Fuwa N, Hida T, Kawahara M, Katakami N, Hirokawa K, Yamamoto N, Fukuoka M, Ariyoshi Y (2007) Phase I\/II trial of sequential chemoradiotherapy using a novel hypoxic cell radiosensitizer, doranidazole (PR-350), in patients with locally advanced non-small-cell lung cancer (WJTOG-0002). Int J Radiat Oncol Biol Phys 69:786\u2013792","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2640_CR28","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1097\/01.coc.0000135739.37072.ff","volume":"27","author":"B Kaplan","year":"2004","unstructured":"Kaplan B, Altynbas M, Eroglu C, Karahacioglu E, Er O, Ozkan M, Bilgin M, Canoz O, Gulmez I, Gulec M (2004) Preliminary results of a phase II study of weekly paclitaxel (PTX) and carboplatin (CBDCA) administered concurrently with thoracic radiation therapy (TRT) followed by consolidation chemotherapy with PTX\/CBDCA for stage III unresectable non-small-cell lung cancer (NSCLC). Am J Clin Oncol 27:603\u2013610","journal-title":"Am J Clin Oncol"}],"updated-by":[{"DOI":"10.1007\/s00384-016-2676-5","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,10,10]],"date-time":"2016-10-10T00:00:00Z","timestamp":1476057600000}}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-016-2640-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00384-016-2640-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-016-2640-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T23:18:42Z","timestamp":1498346322000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00384-016-2640-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,21]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["2640"],"URL":"https:\/\/doi.org\/10.1007\/s00384-016-2640-4","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s00384-016-2676-5","asserted-by":"object"}]},"ISSN":["0179-1958","1432-1262"],"issn-type":[{"value":"0179-1958","type":"print"},{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,21]]}}}