{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T14:55:40Z","timestamp":1744383340017,"version":"3.37.3"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18K07194","19K09114","19K09115","20K09051","20K21626"],"award-info":[{"award-number":["18K07194","19K09114","19K09115","20K09051","20K21626"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["19cm0106502"],"award-info":[{"award-number":["19cm0106502"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1007\/s00384-021-03936-4","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T19:52:31Z","timestamp":1620071551000},"page":"1525-1534","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Therapeutic effects and limitations of chemoradiotherapy in advanced lower rectal cancer focusing on T4b"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2775-2259","authenticated-orcid":false,"given":"Kosuke","family":"Ozaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazushige","family":"Kawai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Nozawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhito","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Murono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigenobu","family":"Emoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuuki","family":"Iida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Anzai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirofumi","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Sugihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soichiro","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,3]]},"reference":[{"key":"3936_CR1","first-page":"470","volume":"24","author":"E Kim","year":"2019","unstructured":"Kim E, Kim K, Oh DH, Han SW, Kim TY, Jung SY, Park KJ, Kang GH, Chie EK (2019) Differential effect of concurrent chemotherapy regimen on clinical outcomes of preoperative chemoradiotherapy for locally advanced rectal cancer. J BUON 24:470\u2013478","journal-title":"J BUON"},{"key":"3936_CR2","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1245\/s10434-010-0985-4","volume":"17","author":"SB Edge","year":"2010","unstructured":"Edge SB, Compton CC (2010) The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 17:1471\u20131474. https:\/\/doi.org\/10.1245\/s10434-010-0985-4","journal-title":"Ann Surg Oncol"},{"key":"3936_CR3","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1007\/s004230050191\/","volume":"384","author":"C Gebhardt","year":"1999","unstructured":"Gebhardt C, Meyer W, Ruckriegel S, Meier U (1999) Multivisceral resection of advanced colorectal carcinoma. Langenbeck's Arch Surg 384:194\u2013199. https:\/\/doi.org\/10.1007\/s004230050191\/","journal-title":"Langenbeck's Arch Surg"},{"key":"3936_CR4","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/BF02555450","volume":"30","author":"FP Gall","year":"1987","unstructured":"Gall FP, Tonak J, Altendorf A (1987) Multivisceral resections in colorectal cancer. Dis Colon Rectum 30:337\u2013341. https:\/\/doi.org\/10.1007\/BF02555450","journal-title":"Dis Colon Rectum"},{"key":"3936_CR5","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1097\/00000658-200202000-00009","volume":"235","author":"T Lehnert","year":"2002","unstructured":"Lehnert T, Methner M, Pollok A, Schaible A, Hinz U, Herfarth C (2002) Multivisceral resection for locally advanced primary colon and rectal cancer: an analysis of prognostic factors in 201 patients. Ann Surg 235:217\u2013225. https:\/\/doi.org\/10.1097\/00000658-200202000-00009","journal-title":"Ann Surg"},{"key":"3936_CR6","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/bf00341238","volume":"6","author":"C Montesani","year":"1991","unstructured":"Montesani C, Ribotta G, De Milito R, Pronio A, D\u2019Amato A, Narilli P, Jaus M (1991) Extended resection in the treatment of colorectal cancer. Int J Color Dis 6:161\u2013164. https:\/\/doi.org\/10.1007\/bf00341238","journal-title":"Int J Color Dis"},{"key":"3936_CR7","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1159\/000342037","volume":"30","author":"PR Larkin","year":"2012","unstructured":"Larkin PR, O\u2019Connell JO (2012) Multivisceral resection for T4 or recurrent colorectal cancer. Dig Dis 30:96\u2013101. https:\/\/doi.org\/10.1159\/000342037","journal-title":"Dig Dis"},{"key":"3936_CR8","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1055\/s-0036-1580722","volume":"29","author":"RM Helewa","year":"2016","unstructured":"Helewa RM, Park J (2016) Surgery for locally advanced T4 rectal cancer: strategies and techniques. Clin Colon Rectal Surg 29:106\u2013113. https:\/\/doi.org\/10.1055\/s-0036-1580722","journal-title":"Clin Colon Rectal Surg"},{"key":"3936_CR9","doi-asserted-by":"publisher","first-page":"iv22","DOI":"10.1093\/annonc\/mdx224","volume":"28","author":"R Glynne-Jones","year":"2017","unstructured":"Glynne-Jones R, Wyrwicz L, Tiret E, Brown G, R\u00f6del C, Cervantes A, Arnold D, ESMO Guidelines Committee (2017) Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 28:iv22\u2013iv40. https:\/\/doi.org\/10.1093\/annonc\/mdx224","journal-title":"Ann Oncol"},{"key":"3936_CR10","doi-asserted-by":"publisher","first-page":"874","DOI":"10.6004\/jnccn.2018.0061","volume":"16","author":"AB Benson","year":"2018","unstructured":"Benson AB, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Gurski L, Freedman-Cass DA (2018) Rectal cancer, version 2.2018, NCCN clinical practice guidelines in oncology. J Natl Compr Cancer Netw 16:874\u2013901. https:\/\/doi.org\/10.6004\/jnccn.2018.0061","journal-title":"J Natl Compr Cancer Netw"},{"key":"3936_CR11","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/bf02051070","volume":"154","author":"JA Hunter","year":"1987","unstructured":"Hunter JA, Ryan JA Jr, Schultz P (1987) En bloc resection of colon cancer adherent to other organs. Am J Surg 154:67\u201371. https:\/\/doi.org\/10.1007\/bf02051070","journal-title":"Am J Surg"},{"key":"3936_CR12","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1002\/bjs.11242","volume":"106","author":"O Peacock","year":"2019","unstructured":"Peacock O, Waters PS, Bressel M, Lynch AC, Wakeman C, Eglinton T, Koh CE, Lee PJ, Austin KK, Warrier SK, Solomon MJ, Frizelle FA, Heriot AG (2019) Prognostic factors and patterns of failure after surgery for T4 rectal cancer in the beyond total mesorectal excision era. Br J Surg 106:1685\u20131696. https:\/\/doi.org\/10.1002\/bjs.11242","journal-title":"Br J Surg"},{"key":"3936_CR13","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1056\/NEJMoa040694","volume":"351","author":"R Sauer","year":"2004","unstructured":"Sauer R, Becker H, Hohenberger W, R\u00f6del C, Wittekind C, Fietkau R, Martus P, Tschmelitsch J, Hager E, Hess CF, Karstens JH, Liersch T, Schmidberger H, Raab R, German Rectal Cancer Study Group (2004) Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351:1731\u20131740. https:\/\/doi.org\/10.1056\/NEJMoa040694","journal-title":"N Engl J Med"},{"key":"3936_CR14","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1056\/NEJM199704033361402","volume":"336","author":"B Cedermark","year":"1997","unstructured":"Swedish Rectal Cancer Trial, Cedermark B, Dahlberg M, Glimelius B, P\u00e5hlman L, Rutqvist LE, Wilking N (1997) Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 336:980\u2013987. https:\/\/doi.org\/10.1056\/NEJM199704033361402","journal-title":"N Engl J Med"},{"key":"3936_CR15","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1056\/NEJMoa060829","volume":"355","author":"JF Bosset","year":"2006","unstructured":"Bosset JF, Collette L, Calais G, Mineur L, Maingon P, Radosevic-Jelic L, Daban A, Bardet E, Beny A, Ollier JC, EORTC Radiotherapy Group Trial 22921 (2006) Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med 355:1114\u20131123. https:\/\/doi.org\/10.1056\/NEJMoa060829","journal-title":"N Engl J Med"},{"key":"3936_CR16","doi-asserted-by":"publisher","first-page":"4620","DOI":"10.1200\/JCO.2006.06.7629","volume":"24","author":"JP G\u00e9rard","year":"2006","unstructured":"G\u00e9rard JP, Conroy T, Bonnetain F, Bouch\u00e9 O, Chapet O, Closon-Dejardin MT, Untereiner M, Leduc B, Francois E, Maurel J, Seitz JF, Buecher B, Mackiewicz R, Ducreux M, Bedenne L (2006) Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203. J Clin Oncol 24:4620\u20134625. https:\/\/doi.org\/10.1200\/JCO.2006.06.7629","journal-title":"J Clin Oncol"},{"key":"3936_CR17","doi-asserted-by":"publisher","first-page":"CD006041","DOI":"10.1002\/14651858.CD006041.pub2","volume":"21","author":"W Ceelen","year":"2009","unstructured":"Ceelen W, Fierens K, Van Nieuwenhove Y, Pattyn P (2009) Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer. Cochrane Database Syst Rev 21:CD006041. https:\/\/doi.org\/10.1002\/14651858.CD006041.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"3936_CR18","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s10147-015-0801-z","volume":"20","author":"T Watanabe","year":"2015","unstructured":"Watanabe T, Itabashi M, Shimada Y, Tanaka S, Ito Y, Ajioka Y, Hamaguchi T, Hyodo I, Igarashi M, Ishida H, Ishihara S, Ishiguro M, Kanemitsu Y, Kokudo N, Muro K, Ochiai A, Oguchi M, Ohkura Y, Saito Y, Sakai Y, Ueno H, Yoshino T, Boku N, Fujimori T, Koinuma N, Morita T, Nishimura G, Sakata Y, Takahashi K, Tsuruta O, Yamaguchi T, Yoshida M, Yamaguchi N, Kotake K, Sugihara K, Japanese Society for Cancer of the Colon and Rectum (2015) Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer. Int J Clin Oncol 20:207\u2013239. https:\/\/doi.org\/10.1007\/s10147-015-0801-z","journal-title":"Int J Clin Oncol"},{"key":"3936_CR19","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1007\/s10350-006-0714-z","volume":"49","author":"K Sugihara","year":"2006","unstructured":"Sugihara K, Kobayashi H, Kato T, Mori T, Mochizuki H, Kameoka S, Shirouzu K, Muto T (2006) Indication and benefit of pelvic sidewall dissection for rectal cancer. Int J Clin Oncol 49:1663\u20131672. https:\/\/doi.org\/10.1007\/s10350-006-0714-z","journal-title":"Int J Clin Oncol"},{"key":"3936_CR20","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1007\/DCR.0b013e3181a1d994","volume":"52","author":"H Kobayashi","year":"2009","unstructured":"Kobayashi H, Mochizuki H, Kato T, Mori T, Kameoka S, Shirouzu K, Sugihara K (2009) Outcomes of surgery alone for lower rectal cancer with and without pelvic sidewall dissection. Dis Colon Rectum 52:567\u2013576. https:\/\/doi.org\/10.1007\/DCR.0b013e3181a1d994","journal-title":"Dis Colon Rectum"},{"key":"3936_CR21","first-page":"436","volume":"19","author":"Y Sun","year":"2016","unstructured":"Sun Y, Chi P, Lin H, Lu X, Huang Y, Xu Z, Huang S, Ye D, Wang X (2016) Analysis of risk factors of distant metastasis in rectal cancer patients who received total mesorectal excision following neoadjuvant chemoradiotherapy. Zhonghua Wei Chang Wai Ke Za Zhi 19:436\u2013441","journal-title":"Zhonghua Wei Chang Wai Ke Za Zhi"},{"key":"3936_CR22","doi-asserted-by":"publisher","first-page":"3223","DOI":"10.1200\/JCO.18.02309","volume":"37","author":"Y Deng","year":"2019","unstructured":"Deng Y, Chi P, Lan P, Wang L, Chen W, Cui L, Chen D, Cao J, Wei H, Peng X, Huang Z, Cai G, Zhao R, Huang Z, Xu L, Zhou H, Wei Y, Zhang H, Zheng J, Huang Y, Zhou Z, Cai Y, Kang L, Huang M, Wu X, Peng J, Ren D, Wang J (2019) Neoadjuvant modified FOLFOX6 with or without radiation versus fluorouracil plus radiation for locally advanced rectal cancer: final results of the Chinese FOWARC trial. J Clin Oncol 37:3223\u20133233. https:\/\/doi.org\/10.1200\/JCO.18.02309","journal-title":"J Clin Oncol"},{"key":"3936_CR23","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1097\/DCR.0000000000000752","volume":"60","author":"S Ishihara","year":"2017","unstructured":"Ishihara S, Kawai K, Tanaka T, Kiyomatsu T, Hata K, Nozawa H, Morikawa T, Watanabe T (2017) Oncological outcomes of lateral pelvic lymph node metastasis in rectal cancer treated with preoperative chemoradiotherapy. Dis Colon Rectum 60:469\u2013476. https:\/\/doi.org\/10.1097\/DCR.0000000000000752","journal-title":"Dis Colon Rectum"},{"key":"3936_CR24","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1097\/DCR.0000000000000830","volume":"60","author":"A Habr-Gama","year":"2017","unstructured":"Habr-Gama A, S\u00e3o Juli\u00e3o GP, Gama-Rodrigues J, Vailati BB, Ortega C, Fernandez LM, Alonso Ara\u00fajo SE, Oliva Perez R (2017) Baseline T classification predicts early tumor regrowth after nonoperative management in distal rectal cancer after extended neoadjuvant chemoradiation and initial complete clinical response. Dis Colon Rectum 60:586\u2013594. https:\/\/doi.org\/10.1097\/DCR.0000000000000830","journal-title":"Dis Colon Rectum"},{"key":"3936_CR25","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1002\/jso.23678","volume":"110","author":"Y Akagi","year":"2014","unstructured":"Akagi Y, Hisaka T, Mizobe T, Kinugasa T, Ogata Y, Shirouzu K (2014) Histopathological predictors for local recurrence in patients with T3 and T4 rectal cancers without preoperative chemoradiotherapy. J Surg Oncol 110:739\u2013744. https:\/\/doi.org\/10.1002\/jso.23678","journal-title":"J Surg Oncol"},{"key":"3936_CR26","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1046\/j.1365-2168.2002.02169_1.x","volume":"89","author":"PJ Arumugam","year":"2002","unstructured":"Arumugam PJ, Vivek V, Beynon J (2002) Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 89:1067. https:\/\/doi.org\/10.1046\/j.1365-2168.2002.02169_1.x","journal-title":"Br J Surg"},{"key":"3936_CR27","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1200\/JCO.2007.12.7027","volume":"26","author":"ID Nagtegaal","year":"2008","unstructured":"Nagtegaal ID, Quirke P (2008) What is the role for the circumferential margin in the modern treatment of rectal cancer? J Clin Oncol 26:303\u2013312. https:\/\/doi.org\/10.1200\/JCO.2007.12.7027","journal-title":"J Clin Oncol"},{"key":"3936_CR28","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1046\/j.0007-1323.2001.02024.x","volume":"89","author":"A Wibe","year":"2002","unstructured":"Wibe A, Rendedal PR, Svensson E, Norstein J, Eide TJ, Myrvold HE, S\u00f8reide O (2002) Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 89:327\u2013334. https:\/\/doi.org\/10.1046\/j.0007-1323.2001.02024.x","journal-title":"Br J Surg"},{"issue":"6","key":"3936_CR29","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1002\/ags3.12372","volume":"4","author":"M Miyo","year":"2020","unstructured":"Miyo M, Kato T, Takahashi Y, Miyake M, Toshiyama R, Hamakawa T, Sakai K, Nishikawa K, Miyamoto A, Hirao M (2020) Short-term and long-term outcomes of laparoscopic colectomy with multivisceral resection for surgical T4b colon cancer: comparison with open colectomy. Ann Gastroenterol Surg 4(6):676\u2013683. https:\/\/doi.org\/10.1002\/ags3.12372","journal-title":"Ann Gastroenterol Surg"},{"key":"3936_CR30","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1007\/s10350-006-0539-9","volume":"49","author":"K Smedh","year":"2006","unstructured":"Smedh K, Hosseinali Khani M, Kraaz W, Raab Y, Strand E (2006) Abdominoperineal excision with partial anterior en bloc resection in multimodal management of low rectal cancer: a strategy to reduce local recurrence. Dis Colon Rectum 49:833\u2013840. https:\/\/doi.org\/10.1007\/s10350-006-0539-9","journal-title":"Dis Colon Rectum"},{"key":"3936_CR31","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1111\/codi.12933","volume":"17","author":"M Frasson","year":"2015","unstructured":"Frasson M, Garcia-Granero E, Paraj\u00f3 A, Garcia-Mayor L, Flor B, Garcia-Granero A, Lavery I (2015) Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate? Results of a multicentre retrospective study. Color Dis 17:689\u2013697. https:\/\/doi.org\/10.1111\/codi.12933","journal-title":"Color Dis"},{"key":"3936_CR32","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1002\/bjs.9192_1","volume":"100","author":"Beyond TME Collaborative","year":"2013","unstructured":"Beyond TME Collaborative (2013) Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes. Br J Surg 100:1009\u20131014. https:\/\/doi.org\/10.1002\/bjs.9192_1","journal-title":"Br J Surg"},{"key":"3936_CR33","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/s1072-7515(99)00229-x","volume":"190","author":"WL Law","year":"2000","unstructured":"Law WL, Chu KW, Choi HK (2000) Total pelvic exenteration for locally advanced rectal cancer. J Am Coll Surg 190:78\u201383. https:\/\/doi.org\/10.1016\/s1072-7515(99)00229-x","journal-title":"J Am Coll Surg"},{"key":"3936_CR34","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1046\/j.1365-2168.2002.02212.x","volume":"89","author":"K Koda","year":"2002","unstructured":"Koda K, Tobe T, Takiguchi N, Oda K, Ito H, Miyazaki M (2002) Pelvic exenteration for advanced colorectal cancer with reconstruction of urinary and sphincter functions. Br J Surg 89:1286\u20131289. https:\/\/doi.org\/10.1046\/j.1365-2168.2002.02212.x","journal-title":"Br J Surg"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-021-03936-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00384-021-03936-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-021-03936-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T13:14:22Z","timestamp":1623417262000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00384-021-03936-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,3]]},"references-count":34,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["3936"],"URL":"https:\/\/doi.org\/10.1007\/s00384-021-03936-4","relation":{},"ISSN":["0179-1958","1432-1262"],"issn-type":[{"type":"print","value":"0179-1958"},{"type":"electronic","value":"1432-1262"}],"subject":[],"published":{"date-parts":[[2021,5,3]]},"assertion":[{"value":"21 April 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the ethics committees of the University of Tokyo Hospital (no. 3252-(10)) and Tokyo Medical and Dental University (no. M2017-268).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was obtained from all participants in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The participant has consented to the submission of the case report to the journal.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}