{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:44:38Z","timestamp":1787579078836,"version":"build-2736575974"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T00:00:00Z","timestamp":1623974400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T00:00:00Z","timestamp":1623974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1007\/s00384-021-03940-8","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T02:02:39Z","timestamp":1623981759000},"page":"2347-2360","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Classification of acute appendicitis (CAA): treatment directed new classification based on imaging (ultrasound, computed tomography) and pathology"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3488-4804","authenticated-orcid":false,"given":"J\u00f6rg C.","family":"Hoffmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus-Peter","family":"Trimborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"F\u00f6rster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Dirks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Tannapfel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Anthuber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alois","family":"Hollerweger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,18]]},"reference":[{"key":"3940_CR1","doi-asserted-by":"publisher","unstructured":"Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De\u2019Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppaniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De\u2019Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F (2020) Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg 15(1):27. https:\/\/doi.org\/10.1186\/s13017-020-00306-3","DOI":"10.1186\/s13017-020-00306-3"},{"issue":"6","key":"3940_CR2","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1097\/SLA.0000000000003225","volume":"270","author":"M Podda","year":"2019","unstructured":"Podda M, Gerardi C, Cillara N, Fearnhead N, Gomes CA, Birindelli A, Mulliri A, Davies RJ, Di Saverio S (2019) Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children: a systematic review and meta-analysis. Ann Surg 270(6):1028\u20131040. https:\/\/doi.org\/10.1097\/SLA.0000000000003225","journal-title":"Ann Surg"},{"issue":"20","key":"3940_CR3","doi-asserted-by":"publisher","first-page":"1907","DOI":"10.1056\/NEJMoa2014320","volume":"383","author":"C Collaborative","year":"2020","unstructured":"Collaborative C, Flum DR, Davidson GH, Monsell SE, Shapiro NI, Odom SR, Sanchez SE, Drake FT, Fischkoff K, Johnson J, Patton JH, Evans H, Cuschieri J, Sabbatini AK, Faine BA, Skeete DA, Liang MK, Sohn V, McGrane K, Kutcher ME, Chung B, Carter DW, Ayoung-Chee P, Chiang W, Rushing A, Steinberg S, Foster CS, Schaetzel SM, Price TP, Mandell KA, Ferrigno L, Salzberg M, DeUgarte DA, Kaji AH, Moran GJ, Saltzman D, Alam HB, Park PK, Kao LS, Thompson CM, Self WH, Yu JT, Wiebusch A, Winchell RJ, Clark S, Krishnadasan A, Fannon E, Lavallee DC, Comstock BA, Bizzell B, Heagerty PJ, Kessler LG, Talan DA (2020) A randomized trial comparing antibiotics with appendectomy for appendicitis. N Engl J Med 383(20):1907\u20131919. https:\/\/doi.org\/10.1056\/NEJMoa2014320","journal-title":"N Engl J Med"},{"issue":"11","key":"3940_CR4","doi-asserted-by":"publisher","first-page":"4668","DOI":"10.1007\/s00464-016-5245-7","volume":"30","author":"RR Gorter","year":"2016","unstructured":"Gorter RR, Eker HH, Gorter-Stam MA, Abis GS, Acharya A, Ankersmit M, Antoniou SA, Arolfo S, Babic B, Boni L, Bruntink M, van Dam DA, Defoort B, Deijen CL, DeLacy FB, Go PM, Harmsen AM, van den Helder RS, Iordache F, Ket JC, Muysoms FE, Ozmen MM, Papoulas M, Rhodes M, Straatman J, Tenhagen M, Turrado V, Vereczkei A, Vilallonga R, Deelder JD, Bonjer J (2016) Diagnosis and management of acute appendicitis. EAES consensus development conference 2015. Surg Endosc 30(11):4668\u20134690. https:\/\/doi.org\/10.1007\/s00464-016-5245-7","journal-title":"Surg Endosc"},{"issue":"1","key":"3940_CR5","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/s1092-9134(00)90011-x","volume":"4","author":"NJ Carr","year":"2000","unstructured":"Carr NJ (2000) The pathology of acute appendicitis. Ann Diagn Pathol 4(1):46\u201358. https:\/\/doi.org\/10.1016\/s1092-9134(00)90011-x","journal-title":"Ann Diagn Pathol"},{"issue":"2","key":"3940_CR6","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.amjsurg.2008.04.016","volume":"197","author":"H Mazeh","year":"2009","unstructured":"Mazeh H, Epelboym I, Reinherz J, Greenstein AJ, Divino CM (2009) Tip appendicitis: clinical implications and management. Am J Surg 197(2):211\u2013215. https:\/\/doi.org\/10.1016\/j.amjsurg.2008.04.016","journal-title":"Am J Surg"},{"issue":"5","key":"3940_CR7","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/j.jpedsurg.2007.12.034","volume":"43","author":"DI Alaedeen","year":"2008","unstructured":"Alaedeen DI, Cook M, Chwals WJ (2008) Appendiceal fecalith is associated with early perforation in pediatric patients. J Pediatr Surg 43(5):889\u2013892. https:\/\/doi.org\/10.1016\/j.jpedsurg.2007.12.034","journal-title":"J Pediatr Surg"},{"issue":"8","key":"3940_CR8","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1007\/s00384-019-03332-z","volume":"34","author":"J Mallinen","year":"2019","unstructured":"Mallinen J, Vaarala S, Makinen M, Lietzen E, Gronroos J, Ohtonen P, Rautio T, Salminen P (2019) Appendicolith appendicitis is clinically complicated acute appendicitis-is it histopathologically different from uncomplicated acute appendicitis. Int J Color Dis 34(8):1393\u20131400. https:\/\/doi.org\/10.1007\/s00384-019-03332-z","journal-title":"Int J Color Dis"},{"issue":"5","key":"3940_CR9","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1007\/s10140-013-1188-7","volume":"21","author":"K Gaetke-Udager","year":"2014","unstructured":"Gaetke-Udager K, Maturen KE, Hammer SG (2014) Beyond acute appendicitis: imaging and pathologic spectrum of appendiceal pathology. Emerg Radiol 21(5):535\u2013542. https:\/\/doi.org\/10.1007\/s10140-013-1188-7","journal-title":"Emerg Radiol"},{"issue":"6","key":"3940_CR10","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.jpedsurg.2016.02.056","volume":"51","author":"JB Mahida","year":"2016","unstructured":"Mahida JB, Lodwick DL, Nacion KM, Sulkowski JP, Leonhart KL, Cooper JN, Ambeba EJ, Deans KJ, Minneci PC (2016) High failure rate of nonoperative management of acute appendicitis with an appendicolith in children. J Pediatr Surg 51(6):908\u2013911. https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.02.056","journal-title":"J Pediatr Surg"},{"issue":"2","key":"3940_CR11","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1007\/s11605-009-1094-1","volume":"14","author":"J Shindoh","year":"2010","unstructured":"Shindoh J, Niwa H, Kawai K, Ohata K, Ishihara Y, Takabayashi N, Kobayashi R, Hiramatsu T (2010) Predictive factors for negative outcomes in initial non-operative management of suspected appendicitis. J Gastrointest Surg 14(2):309\u2013314. https:\/\/doi.org\/10.1007\/s11605-009-1094-1","journal-title":"J Gastrointest Surg"},{"issue":"1","key":"3940_CR12","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/bjs.11440","volume":"107","author":"A Bhangu","year":"2020","unstructured":"Bhangu A, Collaborative RSGobotWMR (2020) Evaluation of appendicitis risk prediction models in adults with suspected appendicitis. Br J Surg 107(1):73\u201386. https:\/\/doi.org\/10.1002\/bjs.11440","journal-title":"Br J Surg"},{"issue":"4","key":"3940_CR13","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/S2352-4642(20)30006-7","volume":"4","author":"Collaborative RSGobotWMR","year":"2020","unstructured":"Collaborative RSGobotWMR (2020) Appendicitis risk prediction models in children presenting with right iliac fossa pain (RIFT study): a prospective, multicentre validation study. Lancet Child Adolesc Health 4(4):271\u2013280. https:\/\/doi.org\/10.1016\/S2352-4642(20)30006-7","journal-title":"Lancet Child Adolesc Health"},{"issue":"4","key":"3940_CR14","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1097\/SLA.0b013e31826a9602","volume":"256","author":"FT Drake","year":"2012","unstructured":"Drake FT, Florence MG, Johnson MG, Jurkovich GJ, Kwon S, Schmidt Z, Thirlby RC, Flum DR, Collaborative S (2012) Progress in the diagnosis of appendicitis: a report from Washington State\u2019s Surgical Care and Outcomes Assessment Program. Ann Surg 256(4):586\u2013594. https:\/\/doi.org\/10.1097\/SLA.0b013e31826a9602","journal-title":"Ann Surg"},{"issue":"3","key":"3940_CR15","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.surg.2016.04.021","volume":"160","author":"E Lietzen","year":"2016","unstructured":"Lietzen E, Mallinen J, Gronroos JM, Rautio T, Paajanen H, Nordstrom P, Aarnio M, Rantanen T, Sand J, Mecklin JP, Jartti A, Virtanen J, Ohtonen P, Salminen P (2016) Is preoperative distinction between complicated and uncomplicated acute appendicitis feasible without imaging? Surgery 160(3):789\u2013795. https:\/\/doi.org\/10.1016\/j.surg.2016.04.021","journal-title":"Surgery"},{"issue":"5","key":"3940_CR16","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1055\/s-2006-927118-2","volume":"27","author":"A Hollerweger","year":"2006","unstructured":"Hollerweger A (2006) Acute appendicitis: sonographic evaluation. Ultraschall Med 27(5):412\u2013426; quiz 427-432. https:\/\/doi.org\/10.1055\/s-2006-927118-2","journal-title":"Ultraschall Med"},{"key":"3940_CR17","first-page":"A303","volume":"154","author":"OJ Bakker","year":"2010","unstructured":"Bakker OJ, Go PM, Puylaert JB, Kazemier G, Heij HA, Werkgroep richtlijn Diagnostiek en behandeling van acute a (2010) Guideline on diagnosis and treatment of acute appendicitis: imaging prior to appendectomy is recommended. Ned Tijdschr Geneeskd 154:A303","journal-title":"Ned Tijdschr Geneeskd"},{"issue":"3","key":"3940_CR18","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s00104-018-0755-6","volume":"90","author":"M Hoffmann","year":"2019","unstructured":"Hoffmann M, Anthuber M (2019) Rational diagnostics of acute appendicitis. Chirurg 90(3):173\u2013177. https:\/\/doi.org\/10.1007\/s00104-018-0755-6","journal-title":"Chirurg"},{"issue":"2","key":"3940_CR19","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1055\/a-0824-6952","volume":"40","author":"K Dirks","year":"2019","unstructured":"Dirks K, Calabrese E, Dietrich CF, Gilja OH, Hausken T, Higginson A, Hollerweger A, Maconi G, Maaser C, Nuernberg D, Nylund K, Pallotta N, Ripolles T, Romanini L, Saftoiu A, Serra C, Wustner M, Sporea I (2019) EFSUMB position paper: recommendations for gastrointestinal ultrasound (GIUS) in acute appendicitis and diverticulitis. Ultraschall Med 40(2):163\u2013175. https:\/\/doi.org\/10.1055\/a-0824-6952","journal-title":"Ultraschall Med"},{"issue":"3","key":"3940_CR20","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1159\/000367625","volume":"90","author":"W Kruis","year":"2014","unstructured":"Kruis W, Germer CT, Leifeld L, German Society for Gastroenterology D, Metabolic D, The German Society for G, Visceral S (2014) Diverticular disease: guidelines of the german society for gastroenterology, digestive and metabolic diseases and the german society for general and visceral surgery. Digestion 90(3):190\u2013207. https:\/\/doi.org\/10.1159\/000367625","journal-title":"Digestion"},{"key":"3940_CR21","doi-asserted-by":"crossref","unstructured":"Brierley JD, Gospodarowicz MK, Wittekind C (2017) TNM classification of malignant tumours. 8th edition edn Oxford","DOI":"10.1002\/9780471420194.tnmc26.pub3"},{"key":"3940_CR22","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jss.2018.03.012","volume":"229","author":"DO Gonzalez","year":"2018","unstructured":"Gonzalez DO, Lawrence AE, Cooper JN, Sola R Jr, Garvey E, Weber BC, St Peter SD, Ostlie DJ, Kohler JE, Leys CM, Deans KJ, Minneci PC (2018) Can ultrasound reliably identify complicated appendicitis in children? J Surg Res 229:76\u201381. https:\/\/doi.org\/10.1016\/j.jss.2018.03.012","journal-title":"J Surg Res"},{"issue":"5","key":"3940_CR23","doi-asserted-by":"publisher","first-page":"957","DOI":"10.2214\/AJR.12.9801","volume":"200","author":"E Blumfield","year":"2013","unstructured":"Blumfield E, Nayak G, Srinivasan R, Muranaka MT, Blitman NM, Blumfield A, Levin TL (2013) Ultrasound for differentiation between perforated and nonperforated appendicitis in pediatric patients. AJR Am J Roentgenol 200(5):957\u2013962. https:\/\/doi.org\/10.2214\/AJR.12.9801","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"3940_CR24","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s10140-012-1093-5","volume":"20","author":"M Ishiyama","year":"2013","unstructured":"Ishiyama M, Yanase F, Taketa T, Makidono A, Suzuki K, Omata F, Saida Y (2013) Significance of size and location of appendicoliths as exacerbating factor of acute appendicitis. Emerg Radiol 20(2):125\u2013130. https:\/\/doi.org\/10.1007\/s10140-012-1093-5","journal-title":"Emerg Radiol"},{"issue":"3","key":"3940_CR25","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1002\/jcu.22655","volume":"47","author":"KJ Kuhn","year":"2019","unstructured":"Kuhn KJ, Brooke Jeffrey R, Olcott EW (2019) Luminal obstruction in uncomplicated appendicitis: detection with sonography and potential clinical implications. J Clin Ultrasound 47(3):113\u2013119. https:\/\/doi.org\/10.1002\/jcu.22655","journal-title":"J Clin Ultrasound"},{"issue":"1099","key":"3940_CR26","doi-asserted-by":"publisher","first-page":"20190102","DOI":"10.1259\/bjr.20190102","volume":"92","author":"T Rawolle","year":"2019","unstructured":"Rawolle T, Reismann M, Minderjahn MI, Bassir C, Hauptmann K, Rothe K, Reismann J (2019) Sonographic differentiation of complicated from uncomplicated appendicitis. Br J Radiol 92(1099):20190102. https:\/\/doi.org\/10.1259\/bjr.20190102","journal-title":"Br J Radiol"},{"issue":"2","key":"3940_CR27","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.surge.2016.08.002","volume":"15","author":"J Forsyth","year":"2017","unstructured":"Forsyth J, Lasithiotakis K, Peter M (2017) The evolving management of the appendix mass in the era of laparoscopy and interventional radiology. Surgeon 15(2):109\u2013115. https:\/\/doi.org\/10.1016\/j.surge.2016.08.002","journal-title":"Surgeon"},{"issue":"5","key":"3940_CR28","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.2214\/AJR.13.12334","volume":"203","author":"ST Chang","year":"2014","unstructured":"Chang ST, Jeffrey RB, Olcott EW (2014) Three-step sequential positioning algorithm during sonographic evaluation for appendicitis increases appendiceal visualization rate and reduces CT use. AJR Am J Roentgenol 203(5):1006\u20131012. https:\/\/doi.org\/10.2214\/AJR.13.12334","journal-title":"AJR Am J Roentgenol"},{"issue":"4","key":"3940_CR29","doi-asserted-by":"publisher","first-page":"863","DOI":"10.2214\/ajr.178.4.1780863","volume":"178","author":"JH Lee","year":"2002","unstructured":"Lee JH, Jeong YK, Hwang JC, Ham SY, Yang SO (2002) Graded compression sonography with adjuvant use of a posterior manual compression technique in the sonographic diagnosis of acute appendicitis. AJR Am J Roentgenol 178(4):863\u2013868. https:\/\/doi.org\/10.2214\/ajr.178.4.1780863","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"3940_CR30","doi-asserted-by":"publisher","first-page":"91","DOI":"10.2214\/ajr.184.1.01840091","volume":"184","author":"JH Lee","year":"2005","unstructured":"Lee JH, Jeong YK, Park KB, Park JK, Jeong AK, Hwang JC (2005) Operator-dependent techniques for graded compression sonography to detect the appendix and diagnose acute appendicitis. AJR Am J Roentgenol 184(1):91\u201397. https:\/\/doi.org\/10.2214\/ajr.184.1.01840091","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"3940_CR31","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1148\/radiology.158.2.2934762","volume":"158","author":"JB Puylaert","year":"1986","unstructured":"Puylaert JB (1986) Acute appendicitis: US evaluation using graded compression. Radiology 158(2):355\u2013360. https:\/\/doi.org\/10.1148\/radiology.158.2.2934762","journal-title":"Radiology"},{"issue":"1","key":"3940_CR32","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/ca.23474","volume":"33","author":"A Kacprzyk","year":"2020","unstructured":"Kacprzyk A, Dro SJ, Stefura T, Krzysztofik M, Jasinska K, Pedziwiatr M, Major P, Holda MK (2020) Variations and morphometric features of the vermiform appendix: a systematic review and meta-analysis of 114,080 subjects with clinical implications. Clin Anat 33(1):85\u201398. https:\/\/doi.org\/10.1002\/ca.23474","journal-title":"Clin Anat"},{"issue":"3","key":"3940_CR33","doi-asserted-by":"publisher","first-page":"W128","DOI":"10.2214\/AJR.17.18059","volume":"209","author":"W Lin","year":"2017","unstructured":"Lin W, Jeffrey RB, Trinh A, Olcott EW (2017) Anatomic reasons for failure to visualize the appendix with graded compression sonography: insights from contemporaneous CT. AJR Am J Roentgenol 209(3):W128\u2013W138. https:\/\/doi.org\/10.2214\/AJR.17.18059","journal-title":"AJR Am J Roentgenol"},{"issue":"13","key":"3940_CR34","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1007\/s00247-015-3443-4","volume":"45","author":"SC Fallon","year":"2015","unstructured":"Fallon SC, Orth RC, Guillerman RP, Munden MM, Zhang W, Elder SC, Cruz AT, Brandt ML, Lopez ME, Bisset GS (2015) Development and validation of an ultrasound scoring system for children with suspected acute appendicitis. Pediatr Radiol 45(13):1945\u20131952. https:\/\/doi.org\/10.1007\/s00247-015-3443-4","journal-title":"Pediatr Radiol"},{"issue":"1","key":"3940_CR35","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1148\/radiol.2017171260","volume":"287","author":"HY Kim","year":"2018","unstructured":"Kim HY, Park JH, Lee YJ, Lee SS, Jeon JJ, Lee KH (2018) Systematic review and meta-analysis of CT features for differentiating complicated and uncomplicated appendicitis. Radiology 287(1):104\u2013115. https:\/\/doi.org\/10.1148\/radiol.2017171260","journal-title":"Radiology"},{"issue":"4","key":"3940_CR36","doi-asserted-by":"publisher","first-page":"849","DOI":"10.2214\/AJR.14.13026","volume":"204","author":"DB Larson","year":"2015","unstructured":"Larson DB, Trout AT, Fierke SR, Towbin AJ (2015) Improvement in diagnostic accuracy of ultrasound of the pediatric appendix through the use of equivocal interpretive categories. AJR Am J Roentgenol 204(4):849\u2013856. https:\/\/doi.org\/10.2214\/AJR.14.13026","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"3940_CR37","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jpedsurg.2014.10.033","volume":"50","author":"JW Nielsen","year":"2015","unstructured":"Nielsen JW, Boomer L, Kurtovic K, Lee E, Kupzyk K, Mallory R, Adler B, Bates DG, Kenney B (2015) Reducing computed tomography scans for appendicitis by introduction of a standardized and validated ultrasonography report template. J Pediatr Surg 50(1):144\u2013148. https:\/\/doi.org\/10.1016\/j.jpedsurg.2014.10.033","journal-title":"J Pediatr Surg"},{"key":"3940_CR38","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.jss.2017.07.002","volume":"221","author":"AB Nordin","year":"2018","unstructured":"Nordin AB, Sales S, Nielsen JW, Adler B, Bates DG, Kenney B (2018) Standardized ultrasound templates for diagnosing appendicitis reduce annual imaging costs. J Surg Res 221:77\u201383. https:\/\/doi.org\/10.1016\/j.jss.2017.07.002","journal-title":"J Surg Res"},{"issue":"5","key":"3940_CR39","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1007\/s00261-014-0280-0","volume":"40","author":"MT Corwin","year":"2015","unstructured":"Corwin MT, Chang M, Fananapazir G, Seibert A, Lamba R (2015) Accuracy and radiation dose reduction of a limited abdominopelvic CT in the diagnosis of acute appendicitis. Abdom Imaging 40(5):1177\u20131182. https:\/\/doi.org\/10.1007\/s00261-014-0280-0","journal-title":"Abdom Imaging"},{"issue":"5","key":"3940_CR40","doi-asserted-by":"publisher","first-page":"1826","DOI":"10.1007\/s00330-017-5159-3","volume":"28","author":"JH Park","year":"2018","unstructured":"Park JH, Jeon JJ, Lee SS, Dhanantwari AC, Sim JY, Kim HY, Lee KH (2018) Can We Perform CT of the Appendix with Less Than 1 mSv? A de-escalating dose-simulation study. Eur Radiol 28(5):1826\u20131834. https:\/\/doi.org\/10.1007\/s00330-017-5159-3","journal-title":"Eur Radiol"},{"issue":"5","key":"3940_CR41","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/s00423-016-1444-x","volume":"401","author":"MO Sauvain","year":"2016","unstructured":"Sauvain MO, Slankamenac K, Muller MK, Wildi S, Metzger U, Schmid W, Wydler J, Clavien PA, Hahnloser D (2016) Delaying surgery to perform CT scans for suspected appendicitis decreases the rate of negative appendectomies without increasing the rate of perforation nor postoperative complications. Langenbeck's Arch Surg 401(5):643\u2013649. https:\/\/doi.org\/10.1007\/s00423-016-1444-x","journal-title":"Langenbeck's Arch Surg"},{"issue":"8","key":"3940_CR42","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/jcu.21928","volume":"40","author":"JK Stewart","year":"2012","unstructured":"Stewart JK, Olcott EW, Jeffrey RB (2012) Sonography for appendicitis: nonvisualization of the appendix is an indication for active clinical observation rather than direct referral for computed tomography. J Clin Ultrasound 40(8):455\u2013461. https:\/\/doi.org\/10.1002\/jcu.21928","journal-title":"J Clin Ultrasound"},{"issue":"9","key":"3940_CR43","doi-asserted-by":"publisher","first-page":"2960","DOI":"10.1007\/s00464-018-6600-7","volume":"33","author":"J Tankel","year":"2019","unstructured":"Tankel J, Yellinek S, Shechter Y, Greenman D, Ioscovich A, Grisaru-Granovsky S, Reissman P (2019) Delaying laparoscopic surgery in pregnant patients with an equivocal acute appendicitis: a step-wise approach does not affect maternal or fetal safety. Surg Endosc 33(9):2960\u20132966. https:\/\/doi.org\/10.1007\/s00464-018-6600-7","journal-title":"Surg Endosc"},{"issue":"11","key":"3940_CR44","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1046\/j.1365-2168.1999.01239.x","volume":"86","author":"B Decadt","year":"1999","unstructured":"Decadt B, Sussman L, Lewis MP, Secker A, Cohen L, Rogers C, Patel A, Rhodes M (1999) Randomized clinical trial of early laparoscopy in the management of acute non-specific abdominal pain. Br J Surg 86(11):1383\u20131386. https:\/\/doi.org\/10.1046\/j.1365-2168.1999.01239.x","journal-title":"Br J Surg"},{"issue":"7","key":"3940_CR45","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s004640000122","volume":"14","author":"M Kraemer","year":"2000","unstructured":"Kraemer M, Ohmann C, Leppert R, Yang Q (2000) Macroscopic assessment of the appendix at diagnostic laparoscopy is reliable. Surg Endosc 14(7):625\u2013633. https:\/\/doi.org\/10.1007\/s004640000122","journal-title":"Surg Endosc"},{"issue":"6","key":"3940_CR46","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1097\/01.sla.0000246886.80424.ad","volume":"244","author":"M Morino","year":"2006","unstructured":"Morino M, Pellegrino L, Castagna E, Farinella E, Mao P (2006) Acute nonspecific abdominal pain: a randomized, controlled trial comparing early laparoscopy versus clinical observation. Ann Surg 244(6):881\u2013886; discussion 886-888. https:\/\/doi.org\/10.1097\/01.sla.0000246886.80424.ad","journal-title":"Ann Surg"},{"issue":"13","key":"3940_CR47","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1002\/bjs.10660","volume":"104","author":"HC Park","year":"2017","unstructured":"Park HC, Kim MJ, Lee BH (2017) Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis. Br J Surg 104(13):1785\u20131790. https:\/\/doi.org\/10.1002\/bjs.10660","journal-title":"Br J Surg"},{"issue":"12","key":"3940_CR48","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1001\/jama.2018.13201","volume":"320","author":"P Salminen","year":"2018","unstructured":"Salminen P, Tuominen R, Paajanen H, Rautio T, Nordstrom P, Aarnio M, Rantanen T, Hurme S, Mecklin JP, Sand J, Virtanen J, Jartti A, Gronroos JM (2018) Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 320(12):1259\u20131265. https:\/\/doi.org\/10.1001\/jama.2018.13201","journal-title":"JAMA"},{"key":"3940_CR49","doi-asserted-by":"publisher","unstructured":"Stoss C, Nitsche U, Neumann PA, Kehl V, Wilhelm D, Busse R, Friess H, Nimptsch U (2021) Acute appendicitis: trends in surgical treatment\u2014a population-based study of over 800 000 patients. Dtsch Arztebl Int 118 (Forthcoming) https:\/\/doi.org\/10.3238\/arztebl.m2021.0118","DOI":"10.3238\/arztebl.m2021.0118"},{"issue":"2","key":"3940_CR50","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1097\/TA.0000000000001962","volume":"85","author":"SV Patel","year":"2018","unstructured":"Patel SV, SJM GPA, Lajkosz K, Nanji S, Brogly SB (2018) Timing of surgery and the risk of complications in patients with acute appendicitis: a population-level case-crossover study. J Trauma Acute Care Surg 85(2):341\u2013347. https:\/\/doi.org\/10.1097\/TA.0000000000001962","journal-title":"J Trauma Acute Care Surg"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-021-03940-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00384-021-03940-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-021-03940-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T10:33:09Z","timestamp":1672482789000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00384-021-03940-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,18]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["3940"],"URL":"https:\/\/doi.org\/10.1007\/s00384-021-03940-8","relation":{},"ISSN":["0179-1958","1432-1262"],"issn-type":[{"value":"0179-1958","type":"print"},{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,18]]},"assertion":[{"value":"21 April 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}