{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:14:26Z","timestamp":1793646866484,"version":"4.5.1"},"reference-count":99,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"College Students Innovation Experiment Program of Hebei Medical University","award":["USIP2019271"],"award-info":[{"award-number":["USIP2019271"]}]},{"name":"the Key Scientific and Technological Research Plan of Hebei Health Commission","award":["20221427"],"award-info":[{"award-number":["20221427"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"DOI":"10.1007\/s00384-023-04333-9","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T23:02:16Z","timestamp":1678402936000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["The role of psychological factors in functional gastrointestinal disorders: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"38","author":[{"given":"Liyanran","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengjiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunchun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"4333_CR1","doi-asserted-by":"publisher","unstructured":"Black CJ, Drossman DA, Talley NJ et al (2020) Functional gastrointestinal disorders: advances in understanding and management. Lancet 396:1664\u20131674.\u00a0https:\/\/doi.org\/10.1016\/s0140-6736(20)32115-2","DOI":"10.1016\/s0140-6736(20)32115-2"},{"key":"4333_CR2","doi-asserted-by":"publisher","unstructured":"Lovell RM, Ford AC (2012) Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol 10:712\u2013721.e4.\u00a0https:\/\/doi.org\/10.1016\/j.cgh.2012.02.029","DOI":"10.1016\/j.cgh.2012.02.029"},{"key":"4333_CR3","doi-asserted-by":"publisher","unstructured":"Mahadeva S, Ford AC (2016) Clinical and epidemiological differences in functional dyspepsia between the East and the West. Neurogastroenterol Motil 28:167\u201374.\u00a0https:\/\/doi.org\/10.1111\/nmo.12657","DOI":"10.1111\/nmo.12657"},{"key":"4333_CR4","doi-asserted-by":"publisher","unstructured":"Enck P, Azpiroz F, Boeckxstaens G et al (2017) Functional dyspepsia. Nat Rev Dis Primers 3:17081.\u00a0https:\/\/doi.org\/10.1038\/nrdp.2017.81","DOI":"10.1038\/nrdp.2017.81"},{"key":"4333_CR5","doi-asserted-by":"publisher","unstructured":"Aziz I, Palsson OS, T\u00f6rnblom H et al (2018)\u00a0\u00a0The prevalence and impact of overlapping Rome IV-diagnosed functional gastrointestinal disorders on somatization, quality of life, and healthcare utilization: a cross-sectional general population study in three countries. Am J Gastroenterol 113:86\u201396.\u00a0https:\/\/doi.org\/10.1038\/ajg.2017.421","DOI":"10.1038\/ajg.2017.421"},{"key":"4333_CR6","doi-asserted-by":"publisher","unstructured":"Mahon J, Lifschitz C, Ludwig T et al (2017) The costs of functional gastrointestinal disorders and related signs and symptoms in infants: a systematic literature review and cost calculation for England. BMJ Open 7:e015594.\u00a0https:\/\/doi.org\/10.1136\/bmjopen-2016-015594","DOI":"10.1136\/bmjopen-2016-015594"},{"key":"4333_CR7","doi-asserted-by":"publisher","unstructured":"Petersen MW, Schr\u00f6der A, J\u00f8rgensen T et al (2020) Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD. Sci Rep 10:3273.\u00a0https:\/\/doi.org\/10.1038\/s41598-020-60318-6","DOI":"10.1038\/s41598-020-60318-6"},{"key":"4333_CR8","doi-asserted-by":"publisher","unstructured":"Gracie DJ, Bercik P, Morgan DG et al (2015) No increase in prevalence of somatization in functional vs organic dyspepsia: a cross-sectional survey. Neurogastroenterol Motil 27:1024\u201331.\u00a0https:\/\/doi.org\/10.1111\/nmo.12578","DOI":"10.1111\/nmo.12578"},{"key":"4333_CR9","doi-asserted-by":"publisher","unstructured":"Bouchoucha M, Mary F, Bon C et al (2018) Sleep quality and functional gastrointestinal disorders. A psychological issue. J Dig Dis 19:84\u201392.\u00a0https:\/\/doi.org\/10.1111\/1751-2980.12577","DOI":"10.1111\/1751-2980.12577"},{"key":"4333_CR10","unstructured":"Heinrich TW (2004) Medically unexplained symptoms and the concept of somatization.\u00a0WMJ-MADISON-\u00a0103:83\u20137"},{"key":"4333_CR11","doi-asserted-by":"publisher","unstructured":"Futagami S, Yamawaki H, Izumi N et al (2013) Impact of sleep disorders in Japanese patients with functional dyspepsia (FD): nizatidine improves clinical symptoms, gastric emptying and sleep disorders in FD patients. J Gastroenterol Hepatol 28:1314\u201320.\u00a0https:\/\/doi.org\/10.1111\/jgh.12236","DOI":"10.1111\/jgh.12236"},{"key":"4333_CR12","doi-asserted-by":"publisher","unstructured":"Lacy BE, Everhart K, Crowell MD (2011) Functional dyspepsia is associated with sleep disorders. Clin Gastroenterol Hepatol 9:410\u20134.\u00a0https:\/\/doi.org\/10.1016\/j.cgh.2011.02.010","DOI":"10.1016\/j.cgh.2011.02.010"},{"key":"4333_CR13","doi-asserted-by":"publisher","unstructured":"Jones MP, Dilley JB, Drossman D et al (2006) Brain-gut connections in functional GI disorders: anatomic and physiologic relationships. Neurogastroenterol Motil 18:91\u2013103.\u00a0https:\/\/doi.org\/10.1111\/j.1365-2982.2005.00730.x","DOI":"10.1111\/j.1365-2982.2005.00730.x"},{"key":"4333_CR14","doi-asserted-by":"publisher","unstructured":"Mohammed AA, Moustafa HA, Nour-Eldein H et al (2021) Association of anxiety-depressive disorders with irritable bowel syndrome among patients attending a rural family practice center: a comparative cross-sectional study. Gen Psychiatr 34:e100553.\u00a0https:\/\/doi.org\/10.1136\/gpsych-2021-100553","DOI":"10.1136\/gpsych-2021-100553"},{"key":"4333_CR15","unstructured":"Sattar A, Salih M, Jafri W (2010) Burden of common mental disorders in patients with functional dyspepsia. J Pak Med Assoc 60:995\u2013997"},{"key":"4333_CR16","doi-asserted-by":"publisher","unstructured":"Keefer L (2018) Behavioural medicine and gastrointestinal disorders: the promise of positive psychology. Nat Rev Gastroenterol Hepatol 15:378\u2013386.\u00a0https:\/\/doi.org\/10.1038\/s41575-018-0001-1","DOI":"10.1038\/s41575-018-0001-1"},{"key":"4333_CR17","doi-asserted-by":"publisher","unstructured":"Staudacher HM, Mikocka-Walus A, Ford AC (2021) Common mental disorders in irritable bowel syndrome: pathophysiology, management, and considerations for future randomised controlled trials. Lancet Gastroenterol Hepatol 6:401\u2013410.\u00a0https:\/\/doi.org\/10.1016\/s2468-1253(20)30363-0","DOI":"10.1016\/s2468-1253(20)30363-0"},{"key":"4333_CR18","doi-asserted-by":"publisher","unstructured":"Drossman DA (2016) Functional gastrointestinal disorders: history, pathophysiology, clinical features and Rome IV. Gastroenterology. https:\/\/doi.org\/10.1053\/j.gastro.2016.02.032","DOI":"10.1053\/j.gastro.2016.02.032"},{"key":"4333_CR19","doi-asserted-by":"publisher","unstructured":"Koloski NA, Jones M, Kalantar J et al (2012) The brain--gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study. Gut 61:1284\u201390.\u00a0https:\/\/doi.org\/10.1136\/gutjnl-2011-300474","DOI":"10.1136\/gutjnl-2011-300474"},{"key":"4333_CR20","doi-asserted-by":"publisher","unstructured":"Koloski N, Holtmann G, Talley NJ (2020) Is there a causal link between psychological disorders and functional gastrointestinal disorders? Expert Rev Gastroenterol Hepatol 14:1047\u20131059.\u00a0https:\/\/doi.org\/10.1080\/17474124.2020.1801414","DOI":"10.1080\/17474124.2020.1801414"},{"key":"4333_CR21","doi-asserted-by":"publisher","unstructured":"Van Oudenhove L, Crowell MD, Drossman DA et al (2016) Biopsychosocial aspects of functional gastrointestinal disorders. Gastroenterology.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2016.02.027","DOI":"10.1053\/j.gastro.2016.02.027"},{"key":"4333_CR22","doi-asserted-by":"publisher","unstructured":"Aro P, Talley NJ, Johansson SE et al (2015) Anxiety is linked to new-onset dyspepsia in the Swedish population: a 10-year follow-up study. Gastroenterology 148:928\u201337.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2015.01.039","DOI":"10.1053\/j.gastro.2015.01.039"},{"key":"4333_CR23","doi-asserted-by":"publisher","unstructured":"Halder SL, Locke GR, 3rd, Schleck CD et al (2007) Natural history of functional gastrointestinal disorders: a 12-year longitudinal population-based study. Gastroenterology 133:799\u2013807.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2007.06.010","DOI":"10.1053\/j.gastro.2007.06.010"},{"key":"4333_CR24","doi-asserted-by":"publisher","unstructured":"Park JM, Choi MG, Cho YK et al (2011) Functional gastrointestinal disorders diagnosed by Rome III questionnaire in Korea. J Neurogastroenterol Motil 17:279\u201386.\u00a0https:\/\/doi.org\/10.5056\/jnm.2011.17.3.279","DOI":"10.5056\/jnm.2011.17.3.279"},{"key":"4333_CR25","doi-asserted-by":"crossref","unstructured":"Choung RS, Chang JY, Locke GR et al (2011) Is having multiple functional gastrointestinal disorders distinct from having a single FGID? A population based study. Gastroenterology 140:S708-S70z","DOI":"10.1016\/S0016-5085(11)62941-7"},{"key":"4333_CR26","doi-asserted-by":"publisher","unstructured":"Talley NJ, Dennis EH, Schettler-Duncan VA et al (2003) Overlapping upper and lower gastrointestinal symptoms in irritable bowel syndrome patients with constipation or diarrhea. Am J Gastroenterol 98:2454\u20139.\u00a0https:\/\/doi.org\/10.1111\/j.1572-0241.2003.07699.x","DOI":"10.1111\/j.1572-0241.2003.07699.x"},{"key":"4333_CR27","doi-asserted-by":"publisher","unstructured":"Corsetti M, Caenepeel P, Fischler B et al (2004) Impact of coexisting irritable bowel syndrome on symptoms and pathophysiological mechanisms in functional dyspepsia. Am J Gastroenterol 99:1152\u20139.\u00a0https:\/\/doi.org\/10.1111\/j.1572-0241.2004.30040.x","DOI":"10.1111\/j.1572-0241.2004.30040.x"},{"key":"4333_CR28","doi-asserted-by":"publisher","unstructured":"Futagami S, Yamawaki H, Shimpuku M et al (2013) Impact of coexisting irritable bowel syndrome and non-erosive reflux disease on postprandial abdominal fullness and sleep disorders in functional dyspepsia. J Nippon Med Sch 80:362\u201370.\u00a0https:\/\/doi.org\/10.1272\/jnms.80.362","DOI":"10.1272\/jnms.80.362"},{"key":"4333_CR29","doi-asserted-by":"publisher","unstructured":"Hartono JL, Mahadeva S, Goh KL (2012) Anxiety and depression in various functional gastrointestinal disorders: do differences exist? J Dig Dis 13:252\u20137.\u00a0https:\/\/doi.org\/10.1111\/j.1751-2980.2012.00581.x","DOI":"10.1111\/j.1751-2980.2012.00581.x"},{"key":"4333_CR30","doi-asserted-by":"publisher","unstructured":"Torun F, Ko\u00e7 G, Ocak Ser\u0131n S et al (2020) Psychiatric symptoms and relationship of disease with stress and traumatic experiences in patients with irritable bowel syndrome. Riv Psichiatr 55:292\u2013296.\u00a0https:\/\/doi.org\/10.1708\/3457.34461","DOI":"10.1708\/3457.34461"},{"key":"4333_CR31","doi-asserted-by":"publisher","unstructured":"Engel GL (1977) The need for a new medical model: a challenge for biomedicine. Science 196:129\u201336.\u00a0https:\/\/doi.org\/10.1126\/science.847460","DOI":"10.1126\/science.847460"},{"key":"4333_CR32","doi-asserted-by":"publisher","unstructured":"Frances A (2014) Resuscitating the biopsychosocial model. Lancet Psychiatr 1:496.\u00a0https:\/\/doi.org\/10.1016\/s2215-0366(14)00058-3","DOI":"10.1016\/s2215-0366(14)00058-3"},{"key":"4333_CR33","doi-asserted-by":"publisher","unstructured":"Page MJ, Moher D, Bossuyt PM et al (2021) PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ 372:n160.\u00a0https:\/\/doi.org\/10.1136\/bmj.n160","DOI":"10.1136\/bmj.n160"},{"key":"4333_CR34","doi-asserted-by":"publisher","unstructured":"Moher D, Shamseer L, Clarke M et al (2015) Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 4:1.\u00a0https:\/\/doi.org\/10.1186\/2046-4053-4-1","DOI":"10.1186\/2046-4053-4-1"},{"key":"4333_CR35","doi-asserted-by":"publisher","unstructured":"Lacy BE, Mearin F, Chang L et al (2016) Bowel disorders. Gastroenterology 150:1393.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2016.02.031","DOI":"10.1053\/j.gastro.2016.02.031"},{"key":"4333_CR36","doi-asserted-by":"publisher","unstructured":"Longstreth GF, Thompson WG, Chey WD et al (2006) Functional bowel disorders. Gastroenterology 130:1480\u20131491.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2005.11.061","DOI":"10.1053\/j.gastro.2005.11.061"},{"key":"4333_CR37","doi-asserted-by":"publisher","unstructured":"Mahadeva S, Goh KL (2011) Anxiety, depression and quality of life differences between functional and organic dyspepsia. J Gastroenterol Hepatol 26 Suppl 3:49\u201352.\u00a0https:\/\/doi.org\/10.1111\/j.1440-1746.2011.06656.x","DOI":"10.1111\/j.1440-1746.2011.06656.x"},{"key":"4333_CR38","doi-asserted-by":"publisher","unstructured":"Xiong N-n, Wei J, Ke M-y et al (2018) Illness perception of patients with functional gastrointestinal disorders. Front Psychiatr 9.\u00a0https:\/\/doi.org\/10.3389\/fpsyt.2018.00122","DOI":"10.3389\/fpsyt.2018.00122"},{"key":"4333_CR39","doi-asserted-by":"publisher","unstructured":"Li Y, Gong Y, Li Y et al (2018) Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria. BMC Psychiatr 18:133.\u00a0https:\/\/doi.org\/10.1186\/s12888-018-1720-0","DOI":"10.1186\/s12888-018-1720-0"},{"key":"4333_CR40","doi-asserted-by":"publisher","unstructured":"Higgins JP, Thompson SG, Deeks JJ et al (2003) Measuring inconsistency in meta-analyses. BMJ 327:557\u201360.\u00a0https:\/\/doi.org\/10.1136\/bmj.327.7414.557","DOI":"10.1136\/bmj.327.7414.557"},{"key":"4333_CR41","doi-asserted-by":"publisher","unstructured":"Higgins JPT, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539\u201358.\u00a0https:\/\/doi.org\/10.1002\/sim.1186","DOI":"10.1002\/sim.1186"},{"key":"4333_CR42","doi-asserted-by":"publisher","unstructured":"Egger M, Davey Smith G, Schneider M et al (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ (Clinical research ed.)\u00a0315:629\u201334.\u00a0https:\/\/doi.org\/10.1136\/bmj.315.7109.629","DOI":"10.1136\/bmj.315.7109.629"},{"key":"4333_CR43","doi-asserted-by":"publisher","unstructured":"Sterne JA, Egger M (2001) Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol 54:1046\u201355.\u00a0https:\/\/doi.org\/10.1016\/s0895-4356(01)00377-8","DOI":"10.1016\/s0895-4356(01)00377-8"},{"key":"4333_CR44","doi-asserted-by":"crossref","unstructured":"Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50:1088\u2013101","DOI":"10.2307\/2533446"},{"key":"4333_CR45","doi-asserted-by":"publisher","unstructured":"Zeng X, Zhang Y, Kwong JSW et al (2015) The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med 8:2\u201310.\u00a0https:\/\/doi.org\/10.1111\/jebm.12141","DOI":"10.1111\/jebm.12141"},{"key":"4333_CR46","doi-asserted-by":"publisher","unstructured":"Selvi K, Bozo O (2022) Group comparison of individuals with and without irritable bowel syndrome in terms of psychological and lifestyle-related factors. Dusunen Adam J Psychiatr Neurol Sci 35:13\u201323.\u00a0https:\/\/doi.org\/10.14744\/DAJPNS.2022.00167","DOI":"10.14744\/DAJPNS.2022.00167"},{"key":"4333_CR47","doi-asserted-by":"publisher","unstructured":"Umrani S, Jamshed W, Rizwan A (2021) Association between psychological disorders and irritable bowel syndrome. Cureus 13:e14513-e14513.\u00a0https:\/\/doi.org\/10.7759\/cureus.14513","DOI":"10.7759\/cureus.14513"},{"key":"4333_CR48","doi-asserted-by":"publisher","unstructured":"Berens S, Schaefert R, Ehrenthal JC et al (2021) Different dimensions of affective processing in patients with irritable bowel syndrome: a multi-center cross-sectional study.\u00a0Front Psychol\u00a012:625381\u2013625381.\u00a0https:\/\/doi.org\/10.3389\/fpsyg.2021.625381","DOI":"10.3389\/fpsyg.2021.625381"},{"key":"4333_CR49","doi-asserted-by":"publisher","unstructured":"Zhang S, Wu L, Zhang B et al (2020) Impaired decision-making under risk in patients with functional dyspepsia. J Clin Exp Neuropsychol 42:771\u2013780.\u00a0https:\/\/doi.org\/10.1080\/13803395.2020.1802406","DOI":"10.1080\/13803395.2020.1802406"},{"key":"4333_CR50","doi-asserted-by":"publisher","unstructured":"Melchior C, Desprez C, Riachi G et al (2020) Anxiety and depression profile is associated with eating disorders in patients with irritable bowel syndrome. Front Psychiatr 10.\u00a0https:\/\/doi.org\/10.3389\/fpsyt.2019.00928","DOI":"10.3389\/fpsyt.2019.00928"},{"key":"4333_CR51","doi-asserted-by":"publisher","unstructured":"McNaughton DT, Andreasson A, Lj\u00f3tsson B et al (2020) Effects of psychology and extragastrointestinal symptoms on health care use by subjects with and without irritable bowel syndrome. Clin Gastroenterol Hepatol 18:847\u2013854.e1.\u00a0https:\/\/doi.org\/10.1016\/j.cgh.2019.07.019","DOI":"10.1016\/j.cgh.2019.07.019"},{"key":"4333_CR52","doi-asserted-by":"publisher","unstructured":"Lee SY, Ryu HS, Choi SC et al (2020) A study of psychological factors associated with functional gastrointestinal disorders and use of health care. Clinical Psychopharmacol Neurosci 18:580\u2013586.\u00a0https:\/\/doi.org\/10.9758\/cpn.2020.18.4.580","DOI":"10.9758\/cpn.2020.18.4.580"},{"key":"4333_CR53","doi-asserted-by":"publisher","unstructured":"Kani HT, Dural U, Kani AS et al (2019) Evaluation of depression, anxiety, alexithymia, attachment, social support and somatization in functional dyspepsia. Psychiatr Clin Psychopharmacol 29:45\u201351.\u00a0https:\/\/doi.org\/10.1080\/24750573.2018.1480081","DOI":"10.1080\/24750573.2018.1480081"},{"key":"4333_CR54","doi-asserted-by":"publisher","unstructured":"Chan Y, So SH, Mak ADP et al (2019) The temporal relationship of daily life stress, emotions, and bowel symptoms in irritable bowel syndrome-Diarrhea subtype: a smartphone-based experience sampling study. Neurogastroenterol Motil 31:e13514.\u00a0https:\/\/doi.org\/10.1111\/nmo.13514","DOI":"10.1111\/nmo.13514"},{"key":"4333_CR55","doi-asserted-by":"publisher","unstructured":"Henrich JF, Gjelsvik B, Martin M (2018) Implicit identification with illness in patients with irritable bowel syndrome (IBS). Cognit Ther Res 42:328\u2013339.\u00a0https:\/\/doi.org\/10.1007\/s10608-017-9888-z","DOI":"10.1007\/s10608-017-9888-z"},{"key":"4333_CR56","doi-asserted-by":"publisher","unstructured":"Arishi AM, Elmakki EE, Hakami OM et al (2021) Irritable bowel syndrome: prevalence and risk factors in Jazan Region, Saudi Arabia. Cureus 13:e15979-e15979.\u00a0https:\/\/doi.org\/10.7759\/cureus.15979","DOI":"10.7759\/cureus.15979"},{"key":"4333_CR57","doi-asserted-by":"publisher","unstructured":"Jemilohun AC, Akande KO, Elikwu CJ et al (2009) Risk factors, psychosocial correlates and health-related quality of life in nigerians with irritable bowel syndrome: a community-based study. J Gastroenterol Hepatol Res 9:3209\u20133216.\u00a0https:\/\/doi.org\/10.17554\/j.issn.2224-3992.2020.09.923","DOI":"10.17554\/j.issn.2224-3992.2020.09.923"},{"key":"4333_CR58","doi-asserted-by":"publisher","unstructured":"Chen H-D, Bair M-J, Chang W-C et al (2020) Similarities and differences between IBS-C and FC with regards to symptomatology, sleep quality and psychological attributes. J Formos Med Assoc 119:75\u201380.\u00a0https:\/\/doi.org\/10.1016\/j.jfma.2019.02.017","DOI":"10.1016\/j.jfma.2019.02.017"},{"key":"4333_CR59","doi-asserted-by":"publisher","unstructured":"Alvand S, Mohammadi Z, Rashidian L et al (2020) Irritable bowel syndrome: psychological disorder or poverty? Results of a large cross-sectional study in Iran. Arch Iran Med 23:821\u2013826.\u00a0https:\/\/doi.org\/10.34172\/aim.2020.109","DOI":"10.34172\/aim.2020.109"},{"key":"4333_CR60","doi-asserted-by":"publisher","unstructured":"Yanartas O, Kani HT, Kani AS et al (2019) Depression and anxiety have unique contributions to somatic complaints in depression, irritable bowel syndrome and inflammatory bowel diseases. Psychiatr Clin Psychopharmacol 29:418\u2013426.\u00a0https:\/\/doi.org\/10.1080\/24750573.2019.1589177","DOI":"10.1080\/24750573.2019.1589177"},{"key":"4333_CR61","doi-asserted-by":"publisher","unstructured":"Huang ZP, Wang K, Duan YH et al (2020) Correlation between lifestyle and social factors in functional dyspepsia among college freshmen. J Int Med Res 48:300060520939702.\u00a0https:\/\/doi.org\/10.1177\/0300060520939702","DOI":"10.1177\/0300060520939702"},{"key":"4333_CR62","doi-asserted-by":"publisher","unstructured":"Beh KH, Chuah KH, Rappek NAM et al (2021) The association of body mass index with functional dyspepsia is independent of psychological morbidity: a cross-sectional study. PloS One 16.\u00a0https:\/\/doi.org\/10.1371\/journal.pone.0245511","DOI":"10.1371\/journal.pone.0245511"},{"key":"4333_CR63","doi-asserted-by":"publisher","unstructured":"Weerts ZZRM, Vork L, Mujagic Z et al (2019) Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome. Neurogastroenterol Motil 31.\u00a0https:\/\/doi.org\/10.1111\/nmo.13629","DOI":"10.1111\/nmo.13629"},{"key":"4333_CR64","doi-asserted-by":"publisher","unstructured":"Schauer B, Grabe HJ, Ittermann T et al (2019) Irritable bowel syndrome, mental health, and quality of life: data from a population-based survey in Germany (SHIP-Trend-0). Neurogastroenterol Motil 31.\u00a0https:\/\/doi.org\/10.1111\/nmo.13511","DOI":"10.1111\/nmo.13511"},{"key":"4333_CR65","doi-asserted-by":"publisher","unstructured":"Hillil\u00e4 MT, H\u00e4m\u00e4l\u00e4inen J, Heikkinen ME et al (2008) Gastrointestinal complaints among subjects with depressive symptoms in the general population. Aliment Pharmacol Ther 28:648\u201354.\u00a0https:\/\/doi.org\/10.1111\/j.1365-2036.2008.03771.x","DOI":"10.1111\/j.1365-2036.2008.03771.x"},{"key":"4333_CR66","doi-asserted-by":"publisher","unstructured":"De Palma G, Lynch MD, Lu J et al (2017) Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice. Sci Transl Med 9.\u00a0https:\/\/doi.org\/10.1126\/scitranslmed.aaf6397","DOI":"10.1126\/scitranslmed.aaf6397"},{"key":"4333_CR67","doi-asserted-by":"publisher","unstructured":"Lee S, Wu J, Ma YL et al (2009) Irritable bowel syndrome is strongly associated with generalized anxiety disorder: a community study. Aliment Pharmacol Ther 30:643\u201351.\u00a0https:\/\/doi.org\/10.1111\/j.1365-2036.2009.04074.x","DOI":"10.1111\/j.1365-2036.2009.04074.x"},{"key":"4333_CR68","doi-asserted-by":"publisher","unstructured":"Naumann J (2016) Effect of amitriptyline and\u00a0escitalopram on functional dyspepsia. Gastroenterology 150:532.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2015.10.051","DOI":"10.1053\/j.gastro.2015.10.051"},{"key":"4333_CR69","doi-asserted-by":"crossref","unstructured":"Clouse RE, Lustman PJ, Geisman RA et al (1994) Antidepressant therapy in 138 patients with irritable bowel syndrome: a five-year clinical experience. Aliment Pharmacol Ther 8:409\u201316","DOI":"10.1111\/j.1365-2036.1994.tb00308.x"},{"key":"4333_CR70","doi-asserted-by":"publisher","unstructured":"T\u00f6rnblom H, Drossman DA (2018) Psychotropics, antidepressants, and visceral analgesics in functional gastrointestinal disorders. Curr Gastroenterol Rep 20:58.\u00a0https:\/\/doi.org\/10.1007\/s11894-018-0664-3","DOI":"10.1007\/s11894-018-0664-3"},{"key":"4333_CR71","doi-asserted-by":"publisher","unstructured":"Hojo M, Nagahara A, Asaoka D et al (2017) A systematic review of the effectiveness of antianxiety and antidepressive agents for functional dyspepsia. Intern Med 56:3127\u20133133.\u00a0https:\/\/doi.org\/10.2169\/internalmedicine.9099-17","DOI":"10.2169\/internalmedicine.9099-17"},{"key":"4333_CR72","doi-asserted-by":"publisher","unstructured":"Esterita T, Dewi S, Suryatenggara FG et al (2021) Association of functional dyspepsia with depression and anxiety: a systematic review. J Gastrointestin Liver Dis 30.\u00a0https:\/\/doi.org\/10.15403\/jgld-3325","DOI":"10.15403\/jgld-3325"},{"key":"4333_CR73","doi-asserted-by":"publisher","unstructured":"Zhang Q-E, Wang F, Qin G et al (2018) Depressive symptoms in patients with irritable bowel syndrome: a meta-analysis of comparative studies. Int J Biol Sci 14:1504\u20131512.\u00a0https:\/\/doi.org\/10.7150\/ijbs.25001","DOI":"10.7150\/ijbs.25001"},{"key":"4333_CR74","doi-asserted-by":"publisher","unstructured":"Koloski NA, Boyce PM, Jones MP et al (2012) What level of IBS symptoms drives impairment in health-related quality of life in community subjects with irritable bowel syndrome? Are current IBS symptom thresholds clinically meaningful? Qual Life Res 21:829\u201336.\u00a0https:\/\/doi.org\/10.1007\/s11136-011-9985-5","DOI":"10.1007\/s11136-011-9985-5"},{"key":"4333_CR75","doi-asserted-by":"publisher","unstructured":"El-Serag HB, Olden K, Bjorkman D (2002) Health-related quality of life among persons with irritable bowel syndrome: a systematic review. Aliment Pharmacol Ther 16:1171\u201385.\u00a0https:\/\/doi.org\/10.1046\/j.1365-2036.2002.01290.x","DOI":"10.1046\/j.1365-2036.2002.01290.x"},{"key":"4333_CR76","doi-asserted-by":"publisher","unstructured":"Creed F, Ratcliffe J, Fernandez L et al (2001) Health-related quality of life and health care costs in severe, refractory irritable bowel syndrome. Ann Intern Med 134:860\u20138.\u00a0https:\/\/doi.org\/10.7326\/0003-4819-134-9_part_2-200105011-00010","DOI":"10.7326\/0003-4819-134-9_part_2-200105011-00010"},{"key":"4333_CR77","doi-asserted-by":"publisher","unstructured":"Thijssen AY, Jonkers DM, Leue C et al (2010) Dysfunctional cognitions, anxiety and depression in irritable bowel syndrome. J Clin Gastroenterol 44:e236\u201341.\u00a0https:\/\/doi.org\/10.1097\/MCG.0b013e3181eed5d8","DOI":"10.1097\/MCG.0b013e3181eed5d8"},{"key":"4333_CR78","doi-asserted-by":"publisher","unstructured":"De Vries DR, Van Herwaarden MA, Baron A et al (2007) Concomitant functional dyspepsia and irritable bowel syndrome decrease health-related quality of life in gastroesophageal reflux disease. Scand J Gastroenterol 42:951\u20136.\u00a0https:\/\/doi.org\/10.1080\/00365520701204204","DOI":"10.1080\/00365520701204204"},{"key":"4333_CR79","doi-asserted-by":"publisher","unstructured":"Hammond JS, Humphries S, Simson N et al (2014) Adherence to enhanced recovery after surgery protocols across a high-volume gastrointestinal surgical service. Dig Surg 31:117\u201322.\u00a0https:\/\/doi.org\/10.1159\/000362097","DOI":"10.1159\/000362097"},{"key":"4333_CR80","doi-asserted-by":"crossref","unstructured":"Hamadeh RR, Al-Roomi KA (2014) Air quality and seasonal variations in consultations for respiratory, allergic, dermatological and gastrointestinal diseases in Bahrain, 2007. East Mediterr Health J 20:309\u201316","DOI":"10.26719\/2014.20.5.309"},{"key":"4333_CR81","doi-asserted-by":"publisher","unstructured":"Talley NJ, Weaver AL, Zinsmeister AR et al (1992) Onset and disappearance of gastrointestinal symptoms and functional gastrointestinal disorders. Am J Epidemiol 136:165\u201377.\u00a0https:\/\/doi.org\/10.1093\/oxfordjournals.aje.a116483","DOI":"10.1093\/oxfordjournals.aje.a116483"},{"key":"4333_CR82","doi-asserted-by":"publisher","unstructured":"Harvey RF, Mauad EC, Brown AM (1987) Prognosis in the irritable bowel syndrome: a 5-year prospective study. Lancet 1:963\u20135.\u00a0https:\/\/doi.org\/10.1016\/s0140-6736(87)90304-7","DOI":"10.1016\/s0140-6736(87)90304-7"},{"key":"4333_CR83","doi-asserted-by":"publisher","unstructured":"Geeraerts B, Vandenberghe J, Van Oudenhove L et al (2005) Influence of experimentally induced anxiety on gastric sensorimotor function in humans. Gastroenterology 129:1437\u201344.\u00a0https:\/\/doi.org\/10.1053\/j.gastro.2005.08.020","DOI":"10.1053\/j.gastro.2005.08.020"},{"key":"4333_CR84","doi-asserted-by":"publisher","unstructured":"Ko SJ, Park JW, Leem J et al (2017) Influence of the patient-practitioner interaction context on acupuncture outcomes in functional dyspepsia: study protocol for a multicenter randomized controlled trial. BMC Complement Altern Med 17:363.\u00a0https:\/\/doi.org\/10.1186\/s12906-017-1869-y","DOI":"10.1186\/s12906-017-1869-y"},{"key":"4333_CR85","doi-asserted-by":"publisher","unstructured":"Hamilton J, Guthrie E, Creed F et al (2000) A randomized controlled trial of psychotherapy in patients with chronic functional dyspepsia. Gastroenterology 119:661\u20139.\u00a0https:\/\/doi.org\/10.1053\/gast.2000.16493","DOI":"10.1053\/gast.2000.16493"},{"key":"4333_CR86","doi-asserted-by":"publisher","unstructured":"Heymann-M\u00f6nnikes I, Arnold R, Florin I et al (2000) The combination of medical treatment plus multicomponent behavioral therapy is superior to medical treatment alone in the therapy of irritable bowel syndrome. Am J Gastroenterol 95:981\u201394.\u00a0https:\/\/doi.org\/10.1111\/j.1572-0241.2000.01937.x","DOI":"10.1111\/j.1572-0241.2000.01937.x"},{"key":"4333_CR87","doi-asserted-by":"publisher","unstructured":"Drossman DA, Toner BB, Whitehead WE et al (2003) Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. Gastroenterology 125:19\u201331.\u00a0https:\/\/doi.org\/10.1016\/s0016-5085(03)00669-3","DOI":"10.1016\/s0016-5085(03)00669-3"},{"key":"4333_CR88","doi-asserted-by":"publisher","unstructured":"Vu J, Kushnir V, Cassell B et al (2014) The impact of psychiatric and extraintestinal comorbidity on quality of life and bowel symptom burden in functional GI disorders. Neurogastroenterol Motil 26:1323\u201332.\u00a0https:\/\/doi.org\/10.1111\/nmo.12396","DOI":"10.1111\/nmo.12396"},{"key":"4333_CR89","doi-asserted-by":"publisher","unstructured":"Lydiard RB (2005) Increased prevalence of functional gastrointestinal disorders in panic disorder: clinical and theoretical implications. CNS Spectr 10:899\u2013908.\u00a0https:\/\/doi.org\/10.1017\/s1092852900019878","DOI":"10.1017\/s1092852900019878"},{"key":"4333_CR90","doi-asserted-by":"publisher","unstructured":"Abbass A, Lumley MA, Town J et al (2021) Short-term psychodynamic psychotherapy for functional somatic disorders: a systematic review and meta-analysis of within-treatment effects. J Psychosom Res 145.\u00a0https:\/\/doi.org\/10.1016\/j.jpsychores.2021.110473","DOI":"10.1016\/j.jpsychores.2021.110473"},{"key":"4333_CR91","doi-asserted-by":"publisher","unstructured":"Kim SY, Choung RS, Lee SK et al (2018) Self-reported sleep impairment in functional dyspepsia and irritable bowel syndrome. J Neurogastroenterol Motil 24:280\u2013288.\u00a0https:\/\/doi.org\/10.5056\/jnm17098","DOI":"10.5056\/jnm17098"},{"key":"4333_CR92","doi-asserted-by":"publisher","unstructured":"Bouchoucha M, Devroede G, Girault-Lidvan N et al (2020) Psychological profiles of irritable bowel syndrome patients with different phenotypes. Intes Res 18:459\u2013468.\u00a0https:\/\/doi.org\/10.5217\/ir.2019.09171","DOI":"10.5217\/ir.2019.09171"},{"key":"4333_CR93","doi-asserted-by":"publisher","unstructured":"Wichniak A, Wierzbicka A, Jernajczyk W (2013) Sleep as a biomarker for depression. Int Rev Psychiatr 25:632\u201345.\u00a0https:\/\/doi.org\/10.3109\/09540261.2013.812067","DOI":"10.3109\/09540261.2013.812067"},{"key":"4333_CR94","doi-asserted-by":"publisher","unstructured":"Kano M, Muratsubaki T, Yagihashi M et al (2020) Insula activity to visceral stimulation and endocrine stress responses as associated with alexithymia in patients with irritable bowel syndrome.\u00a0Psychosom Med\u00a082:29\u201338.\u00a0https:\/\/doi.org\/10.1097\/psy.0000000000000729","DOI":"10.1097\/psy.0000000000000729"},{"key":"4333_CR95","doi-asserted-by":"publisher","unstructured":"Popa SL, Leucuta DC, Dumitrascu DL (2018) Pressure management as an occupational stress risk factor in irritable bowel syndrome a cross-sectional study. Medicine 97.\u00a0https:\/\/doi.org\/10.1097\/md.0000000000013562","DOI":"10.1097\/md.0000000000013562"},{"key":"4333_CR96","doi-asserted-by":"publisher","unstructured":"Nam Y, Kwon S-C, Lee Y-J et al (2018) Relationship between job stress and functional dyspepsia in display manufacturing sector workers: a cross-sectional study. Ann Occup Environ Med 30:62\u201362.\u00a0https:\/\/doi.org\/10.1186\/s40557-018-0274-4","DOI":"10.1186\/s40557-018-0274-4"},{"key":"4333_CR97","doi-asserted-by":"publisher","unstructured":"Deutsch D, Bouchoucha M, Devroede G et al (2021) Functional gastrointestinal disorders as predictors of suicidal ideation. An observational study. Eur J Gastroenterol Hepatol 33:E758-E765.\u00a0https:\/\/doi.org\/10.1097\/meg.0000000000002245","DOI":"10.1097\/meg.0000000000002245"},{"key":"4333_CR98","doi-asserted-by":"publisher","unstructured":"Dong Y, Baumeister D, Berens S et al (2020) Stressful life events moderate the relationship between changes in symptom severity and health-related quality of life in patients with irritable bowel syndrome. J Clin Gastroenterol 54:445\u2013451.\u00a0https:\/\/doi.org\/10.1097\/mcg.0000000000001261","DOI":"10.1097\/mcg.0000000000001261"},{"key":"4333_CR99","doi-asserted-by":"publisher","unstructured":"Wong KM, Mak ADP, Yuen SY et al (2019) Nature and specificity of altered cognitive functioning in IBS. Neurogastroenterol Motil 31:e13696.\u00a0https:\/\/doi.org\/10.1111\/nmo.13696","DOI":"10.1111\/nmo.13696"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-023-04333-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00384-023-04333-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-023-04333-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T11:13:47Z","timestamp":1703157227000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00384-023-04333-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,9]]},"references-count":99,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["4333"],"URL":"https:\/\/doi.org\/10.1007\/s00384-023-04333-9","relation":{},"ISSN":["1432-1262"],"issn-type":[{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,9]]},"assertion":[{"value":"4 February 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"65"}}