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The aim of this study was to determine the direct impact of obesity on postoperative outcomes using data from a large clinical registry.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Method<\/jats:title>\n                <jats:p>The Binational Colorectal Cancer Audit registry was used to identify patients who underwent rectal cancer surgery in Australia and New Zealand from 2007\u20132021. Primary outcomes were inpatient surgical and medical complications. Logistic regression models were developed to describe the association between body-mass index (BMI) and outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among 3,708 patients (median age 66\u00a0years [IQR 56.75\u201375], 65.0% male), 2.0% had a BMI\u2009&lt;\u200918.5\u00a0kg\/m<jats:sup>2<\/jats:sup>, 35.4% had a BMI of 18.5\u201324.9\u00a0kg\/m<jats:sup>2<\/jats:sup>, 37.6% had a BMI of 25.0\u201329.9\u00a0kg\/m<jats:sup>2<\/jats:sup>, 16.7% had a BMI of 30.0\u201334.9\u00a0kg\/m<jats:sup>2<\/jats:sup>, and 8.2% had a BMI\u2009\u2265\u200935.0\u00a0kg\/m<jats:sup>2<\/jats:sup>. Surgical complications occurred in 27.7% of patients with a BMI of 18.5\u201324.9\u00a0kg\/m<jats:sup>2<\/jats:sup>, 26.6% of patients with a BMI of 25.0\u201329.9\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 0.91, 95% CI 0.76\u20131.10), 28.5% with a BMI of 30.0\u201334.9\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 0.96, 95% CI 0.76\u20131.21), and 33.2% with a BMI\u2009\u2265\u200935.0\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 1.27, 95% CI 0.94\u20131.71). Modelling BMI as a continuous variable confirmed a J-shaped relationship. The association between BMI and medical complications was more linear.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Risk of postoperative complications is increased in patients with obesity undergoing rectal cancer surgery.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00384-023-04447-0","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T10:01:58Z","timestamp":1686218518000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Impact of obesity on patients undergoing surgery for rectal cancer in Australia and New Zealand"],"prefix":"10.1007","volume":"38","author":[{"given":"Phillip F","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen Hao","family":"Ang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarit","family":"Badiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe R","family":"Berney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew J","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"4447_CR1","unstructured":"Australian Institute of Health and Welfare\u00a0(2020) Overweight and obesity. 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