{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T10:19:14Z","timestamp":1791627554305,"version":"4.3.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1160443"],"award-info":[{"award-number":["APP1160443"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1160443"],"award-info":[{"award-number":["APP1160443"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022217","name":"Flinders Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022217","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Eiken Chemical Company"},{"DOI":"10.13039\/501100001785","name":"Flinders University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001785","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>There is increasing demand for colorectal cancer (CRC) surveillance, but healthcare capacity is limited. The burden on colonoscopy resources could be reduced by personalizing surveillance frequency using the fecal immunochemical test (FIT). This study will determine the safety, cost-effectiveness, and patient acceptance of using FIT to extend surveillance colonoscopy intervals for individuals at elevated risk of CRC.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This multicenter, prospective, randomized controlled trial will invite participants who are scheduled for surveillance colonoscopy (due to a personal history of adenomas or a family history of CRC) and who have returned a low fecal hemoglobin (&lt;\u20092\u00a0\u03bcg Hb\/g feces; F-Hb) using a two-sample FIT (OC Sensor, Eiken Chemical Company) in the prior 3\u00a0years. A total of 1344 individuals will be randomized to either surveillance colonoscopy as scheduled or delayed by 1 or 2\u00a0years for individuals originally recommended a 3- or 5-year surveillance interval, respectively. The primary endpoint is incidence of advanced neoplasia (advanced adenoma and\/or CRC). Secondary endpoints include cost-effectiveness and consumer acceptability of extending surveillance intervals, determined using surveys and discrete choice experiments.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study will establish the safety, cost-effectiveness, and acceptability of utilizing a low FIT Hb result to extend colonoscopy surveillance intervals in a cohort at elevated risk for CRC. This personalized approach to CRC surveillance will lead to a reduction in unnecessary colonoscopies, increases in healthcare savings, and a better patient experience.\u00a0<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Trial registration<\/jats:title>\n                <jats:p>Registration was approved on December 9, 2019 with the Australian New Zealand Clinical Trials Registry ANZCTR 12619001743156.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00384-023-04493-8","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T08:01:59Z","timestamp":1690272119000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["FIT for purpose: study protocol for a randomized controlled trial to personalize surveillance colonoscopy for individuals at elevated risk of colorectal cancer"],"prefix":"10.1007","volume":"38","author":[{"given":"Jean M.","family":"Winter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn J.","family":"Cornthwaite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme P.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlene","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Woodman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Coats","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Fraser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Cock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Bampton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin L.","family":"Symonds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,25]]},"reference":[{"key":"4493_CR1","doi-asserted-by":"crossref","unstructured":"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: Cancer J Clin\u00a071(3):209\u2013249","DOI":"10.3322\/caac.21660"},{"issue":"10","key":"4493_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2021.101174","volume":"14","author":"Y Xi","year":"2021","unstructured":"Xi Y, Xu P (2021) Global colorectal cancer burden in 2020 and projections to 2040. Transl Oncol 14(10):101174","journal-title":"Translational Oncology"},{"issue":"4","key":"4493_CR3","doi-asserted-by":"publisher","first-page":"e214708","DOI":"10.1001\/jamanetworkopen.2021.4708","volume":"4","author":"L Rahib","year":"2021","unstructured":"Rahib L, Wehner MR, Matrisian LM, Nead KT (2021) Estimated projection of US cancer incidence and death to 2040. JAMA Netw Open 4(4):e214708\u2013e214708","journal-title":"JAMA Netw Open"},{"issue":"8","key":"4493_CR4","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1056\/NEJMoa1100370","volume":"366","author":"AG Zauber","year":"2012","unstructured":"Zauber AG, Winawer SJ, O\u2019Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF et al (2012) Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med 366(8):687\u2013696","journal-title":"N Engl J Med"},{"key":"4493_CR5","doi-asserted-by":"crossref","unstructured":"Megan A. Adams MDJDM, Joel H. Rubenstein MDM, Holleman R, Lipson R, Mandi L. Klamerus MPH, Zoulek S et al (2022) Rising use of surveillance colonoscopy and potential impacts.\u00a0Am J Manag Care 28","DOI":"10.37765\/ajmc.2022.89144"},{"issue":"2","key":"4493_CR6","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.cgh.2009.10.007","volume":"8","author":"CW Ko","year":"2010","unstructured":"Ko CW, Riffle S, Michaels L, Morris C, Holub J, Shapiro JA et al (2010) Serious complications within 30 days of screening and surveillance colonoscopy are uncommon. Clin Gastroenterol Hepatol 8(2):166\u2013173","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"4493_CR7","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1093\/epirev\/mxx002","volume":"39","author":"E McFerran","year":"2017","unstructured":"McFerran E, O\u2019Mahony JF, Fallis R, McVicar D, Zauber AG, Kee F (2017) Evaluation of the effectiveness and cost-effectiveness of personalized surveillance after colorectal adenomatous polypectomy. Epidemiol Rev 39(1):148\u2013160","journal-title":"Epidemiol Rev"},{"issue":"6","key":"4493_CR8","doi-asserted-by":"publisher","first-page":"327","DOI":"10.5694\/mja12.11357","volume":"198","author":"SR Cole","year":"2013","unstructured":"Cole SR, Tucker GR, Osborne JM, Byrne SE, Bampton PA, Fraser RJ et al (2013) Shift to earlier stage at diagnosis as a consequence of the National Bowel Cancer Screening Program. Med J Aust 198(6):327\u2013330","journal-title":"Med J Aust"},{"issue":"1","key":"4493_CR9","doi-asserted-by":"publisher","first-page":"56","DOI":"10.14309\/ajg.0000000000000465","volume":"115","author":"T Niedermaier","year":"2020","unstructured":"Niedermaier T, Balavarca Y, Brenner H (2020) Stage-specific sensitivity of fecal immunochemical tests for detecting colorectal cancer: systematic review and meta-analysis. Am J Gastroenterol 115(1):56\u201369","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"4493_CR10","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1136\/jclinpath-2013-201445","volume":"66","author":"J Digby","year":"2013","unstructured":"Digby J, Fraser CG, Carey FA, McDonald PJ, Strachan JA, Diament RH et al (2013) Faecal haemoglobin concentration is related to severity of colorectal neoplasia. J Clin Pathol 66(5):415\u2013419","journal-title":"J Clin Pathol"},{"issue":"5","key":"4493_CR11","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1053\/j.gastro.2017.07.034","volume":"153","author":"EJ Grobbee","year":"2017","unstructured":"Grobbee EJ, Schreuders EH, Hansen BE, Bruno MJ, Lansdorp-Vogelaar I, Spaander MCW et al (2017) Association between concentrations of hemoglobin determined by fecal immunochemical tests and long-term development of advanced colorectal neoplasia. Gastroenterology 153(5):1251-1259.e2","journal-title":"Gastroenterology"},{"issue":"1","key":"4493_CR12","first-page":"101","volume":"72","author":"RGS Meester","year":"2023","unstructured":"Meester RGS, van de Schootbrugge-Vandermeer HJ, Breekveldt ECH, de Jonge L, Toes-Zoutendijk E, Kooyker A et al (2023) Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model Gut 72(1):101\u2013108","journal-title":"A prognostic model Gut"},{"key":"4493_CR13","doi-asserted-by":"crossref","unstructured":"Terhaar sive Droste JS, van Turenhout ST, Oort FA, van der Hulst RW, Steeman VA, Coblijn U et al\u00a0 (2012) Faecal immunochemical test accuracy in patients referred for surveillance colonoscopy: a multi-centre cohort study. BMC Gastroenterol 12:94","DOI":"10.1186\/1471-230X-12-94"},{"key":"4493_CR14","unstructured":"Cancer Council Australia Colorectal Cancer Guidelines Working Party. Clinical practice guidelines for the prevention, early detection and management of colorectal cancer. Sydney: Cancer Council Australia. [Version URL: https:\/\/wiki.cancer.org.au\/australiawiki\/index.php?oldid=213460\u00a0cited 2023 Feb 17]. Available from: https:\/\/wiki.cancer.org.au\/australia\/Guidelines:Colorectal_cancer"},{"key":"4493_CR15","unstructured":"Cancer Council Australia Surveillance Colonoscopy Guidelines Working Party. Clinical practice guidelines for surveillance colonoscopy. Sydney: Cancer Council Australia. [Version URL: https:\/\/wiki.cancer.org.au\/australiawiki\/index.php?oldid=215532cited 2023 Feb 17]. Available from: https:\/\/wiki.cancer.org.au\/australia\/Guidelines:Colorectal_cancer\/Colonoscopy_surveillance"},{"issue":"3","key":"4493_CR16","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1053\/j.gastro.2012.06.001","volume":"143","author":"DA Lieberman","year":"2012","unstructured":"Lieberman DA, Rex DK, Winawer SJ, Giardiello FM, Johnson DA, Levin TR (2012) Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology 143(3):844\u2013857","journal-title":"Gastroenterology"},{"issue":"10","key":"4493_CR17","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1055\/s-0033-1344548","volume":"45","author":"C Hassan","year":"2013","unstructured":"Hassan C, Quintero E, Dumonceau JM, Regula J, Brand\u00e3o C, Chaussade S et al (2013) Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 45(10):842\u2013851","journal-title":"Endoscopy"},{"issue":"7","key":"4493_CR18","doi-asserted-by":"publisher","first-page":"e331","DOI":"10.1016\/S2468-2667(17)30105-6","volume":"2","author":"JB Lew","year":"2017","unstructured":"Lew JB, St John DJB, Xu XM, Greuter MJE, Caruana M, Cenin DR et al (2017) Long-term evaluation of benefits, harms, and cost-effectiveness of the National Bowel Cancer Screening Program in Australia: a modelling study. Lancet Public Health 2(7):e331\u2013e340","journal-title":"Lancet Public Health"},{"issue":"4","key":"4493_CR19","doi-asserted-by":"publisher","first-page":"180","DOI":"10.5694\/j.1326-5377.2011.tb03766.x","volume":"194","author":"MP Pignone","year":"2011","unstructured":"Pignone MP, Flitcroft KL, Howard K, Trevena LJ, Salkeld GP, St John DJ (2011) Costs and cost-effectiveness of full implementation of a biennial faecal occult blood test screening program for bowel cancer in Australia. Med J Aust 194(4):180\u2013185","journal-title":"Med J Aust"},{"key":"4493_CR20","doi-asserted-by":"crossref","unstructured":"Saini SD, Schoenfeld P, Vijan S (2010) Surveillance colonoscopy is cost-effective for patients with adenomas who are at high risk of colorectal cancer. Gastroenterology\u00a0138(7):2292\u20132299.e1","DOI":"10.1053\/j.gastro.2010.03.004"},{"key":"4493_CR21","doi-asserted-by":"crossref","unstructured":"Nicol\u00e1s D, Castilla-Rodr\u00edguez I, Salgado-Fern\u00e1ndez M, Cougil MP, M, Oca\u00f1a TB, L, Sopena F et al (2017) Annual fecal immunochemical testing is as effective as colonoscopy every 5 years for familial colorectal cancer screening. Gastroenterology\u00a0152:S542","DOI":"10.1016\/S0016-5085(17)31973-X"},{"issue":"6","key":"4493_CR22","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1002\/pon.2070","volume":"21","author":"B Thewes","year":"2012","unstructured":"Thewes B, Butow P, Zachariae R, Christensen S, Simard S, Gotay C (2012) Fear of cancer recurrence: a systematic literature review of self-report measures. Psychooncology 21(6):571\u2013587","journal-title":"Psychooncology"},{"issue":"5","key":"4493_CR23","doi-asserted-by":"publisher","first-page":"809","DOI":"10.2105\/AJPH.2004.049684","volume":"96","author":"RL Wolf","year":"2006","unstructured":"Wolf RL, Basch CE, Brouse CH, Shmukler C, Shea S (2006) Patient preferences and adherence to colorectal cancer screening in an urban population. Am J Public Health 96(5):809\u2013811","journal-title":"Am J Public Health"},{"issue":"4s","key":"4493_CR24","doi-asserted-by":"publisher","first-page":"S71","DOI":"10.1037\/0278-6133.24.4.S71","volume":"24","author":"RE Myers","year":"2005","unstructured":"Myers RE (2005) Decision counseling in cancer prevention and control. Health Psychol 24(4s):S71\u2013S77","journal-title":"Health Psychol"},{"issue":"3","key":"4493_CR25","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.pec.2009.12.015","volume":"78","author":"JH Hibbard","year":"2010","unstructured":"Hibbard JH, Mahoney E (2010) Toward a theory of patient and consumer activation. Patient Educ Couns 78(3):377\u2013381","journal-title":"Patient Educ Couns"},{"issue":"3","key":"4493_CR26","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1177\/0969141313503953","volume":"20","author":"HL Bowyer","year":"2013","unstructured":"Bowyer HL, Vart G, Kralj-Hans I, Atkin W, Halloran SP, Seaman H et al (2013) Patient attitudes towards faecal immunochemical testing for haemoglobin as an alternative to colonoscopic surveillance of groups at increased risk of colorectal cancer. J Med Screen 20(3):149\u2013156","journal-title":"J Med Screen"},{"key":"4493_CR27","doi-asserted-by":"crossref","unstructured":"Bonello B, Ghanouni A, Bowyer HL, MacRae E, Atkin W, Halloran SP et al (2016) Using a hypothetical scenario to assess public preferences for colorectal surveillance following screening-detected, intermediate-risk adenomas: annual home-based stool test vs. triennial colonoscopy. BMC Gastroenterol 16(1):113","DOI":"10.1186\/s12876-016-0517-1"},{"issue":"11","key":"4493_CR28","doi-asserted-by":"publisher","first-page":"492","DOI":"10.5694\/mja17.00823","volume":"208","author":"EL Symonds","year":"2018","unstructured":"Symonds EL, Simpson K, Coats M, Chaplin A, Saxty K, Sandford J et al (2018) A nurse-led model at public academic hospitals maintains high adherence to colorectal cancer surveillance guidelines. Med J Aust 208(11):492\u2013496","journal-title":"Med J Aust"},{"issue":"4","key":"4493_CR29","doi-asserted-by":"publisher","first-page":"155","DOI":"10.5694\/j.1326-5377.2002.tb04344.x","volume":"176","author":"PA Bampton","year":"2002","unstructured":"Bampton PA, Sandford JJ, Young GP (2002) Applying evidence-based guidelines improves use of colonoscopy resources in patients with a moderate risk of colorectal neoplasia. Med J Aust 176(4):155\u2013157","journal-title":"Med J Aust"},{"issue":"6","key":"4493_CR30","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1136\/gut.2004.043786","volume":"54","author":"PA Bampton","year":"2005","unstructured":"Bampton PA, Sandford JJ, Cole SR, Smith A, Morcom J, Cadd B et al (2005) Interval faecal occult blood testing in a colonoscopy based screening programme detects additional pathology. Gut 54(6):803\u2013806","journal-title":"Gut"},{"issue":"6","key":"4493_CR31","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.1053\/j.gastro.2010.08.005","volume":"139","author":"JM Lane","year":"2010","unstructured":"Lane JM, Chow E, Young GP, Good N, Smith A, Bull J et al (2010) Interval fecal immunochemical testing in a colonoscopic surveillance program speeds detection of colorectal neoplasia. Gastroenterology 139(6):1918\u20131926","journal-title":"Gastroenterology"},{"key":"4493_CR32","unstructured":"Cancer Council Australia Colorectal Cancer Guidelines Working Party. Clinical practice guidelines for the prevention, early detection and management of colorectal cancer. Sydney: Cancer Council Australia. Version URL:\u00a0https:\/\/wiki.cancer.org.au\/australiawiki\/index.php?oldid=213460\u00a0cited 2023 Apr 12. Available from: https:\/\/wiki.cancer.org.au\/australia\/Guidelines:Colorectal_cancer"},{"issue":"1","key":"4493_CR33","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1155\/2013\/279897","volume":"27","author":"E Schreuders","year":"2013","unstructured":"Schreuders E, Sint Nicolaas J, de Jonge V, van Kooten H, Soo I, Sadowski D et al (2013) The appropriateness of surveillance colonoscopy intervals after polypectomy. Can J Gastroenterol 27(1):33\u201338","journal-title":"Can J Gastroenterol"},{"issue":"6","key":"4493_CR34","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1111\/jgh.15823","volume":"37","author":"MM Wassie","year":"2022","unstructured":"Wassie MM, Young GP, Cock C, Bampton P, Winter JM, Simpson K et al (2022) Faecal immunochemical test mitigates risk of delayed colonoscopy in people with elevated risk of colorectal neoplasia. J Gastroenterol Hepatol 37(6):1067\u20131075","journal-title":"J Gastroenterol Hepatol"},{"issue":"10","key":"4493_CR35","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1007\/s00384-014-1980-1","volume":"29","author":"D Stein","year":"2014","unstructured":"Stein D, Joulain F, Naoshy S, Iqbal U, Muszbek N, Payne KA et al (2014) Assessing health-state utility values in patients with metastatic colorectal cancer: a utility study in the United Kingdom and the Netherlands. Int J Colorectal Dis 29(10):1203\u20131210","journal-title":"Int J Colorectal Dis"},{"issue":"4","key":"4493_CR36","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1177\/0969141315584783","volume":"22","author":"EL Symonds","year":"2015","unstructured":"Symonds EL, Osborne JM, Cole SR, Bampton PA, Fraser RJL, Young GP (2015) Factors affecting faecal immunochemical test positive rates: demographic, pathological, behavioural and environmental variables. J Med Screen 22(4):187\u2013193","journal-title":"J Med Screen"},{"issue":"3 Pt 2","key":"4493_CR37","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.gie.2008.05.057","volume":"69","author":"EJ Lai","year":"2009","unstructured":"Lai EJ, Calderwood AH, Doros G, Fix OK, Jacobson BC (2009) The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research. Gastrointest Endosc 69(3 Pt 2):620\u2013625","journal-title":"Gastrointest Endosc"},{"issue":"4","key":"4493_CR38","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1136\/gutjnl-2019-318370","volume":"69","author":"EL Symonds","year":"2020","unstructured":"Symonds EL, Cornthwaite K, Fraser RJL, Bampton P, Cock C, Young GP (2020) Reducing the number of surveillance colonoscopies with faecal immunochemical tests. Gut 69(4):784","journal-title":"Gut"},{"issue":"3","key":"4493_CR39","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1177\/0272989X17753392","volume":"38","author":"MS Wolf","year":"2018","unstructured":"Wolf MS, Smith SG, Pandit AU, Condon DM, Curtis LM, Griffith J et al (2018) Development and validation of the consumer health activation index. Med Decis Making 38(3):334\u2013343","journal-title":"Med Decis Making"},{"issue":"5","key":"4493_CR40","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1177\/2050640620913674","volume":"8","author":"J Digby","year":"2020","unstructured":"Digby J, Cleary S, Gray L, Datt P, Goudie DR, Steele RJC et al (2020) Faecal haemoglobin can define risk of colorectal neoplasia at surveillance colonoscopy in patients at increased risk of colorectal cancer. United European Gastroenterology Journal 8(5):559\u2013566","journal-title":"United European Gastroenterology Journal"},{"issue":"3","key":"4493_CR41","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1136\/gutjnl-2018-318198","volume":"69","author":"C Senore","year":"2020","unstructured":"Senore C, Zappa M, Campari C, Crotta S, Armaroli P, Arrigoni A et al (2020) Faecal haemoglobin concentration among subjects with negative FIT results is associated with the detection rate of neoplasia at subsequent rounds: a prospective study in the context of population based screening programmes in Italy. Gut 69(3):523\u2013530","journal-title":"Gut"},{"key":"4493_CR42","doi-asserted-by":"publisher","first-page":"234","DOI":"10.3389\/fpubh.2017.00234","volume":"5","author":"DB Preen","year":"2017","unstructured":"Preen DB, Lansdorp-Vogelaar I, Ee HC, Platell C, Cenin DR, Troeung L et al (2017) Optimizing patient risk stratification for colonoscopy screening and surveillance of colorectal cancer: the role for linked data. Front Public Health 5:234","journal-title":"Front Public Health"},{"issue":"6","key":"4493_CR43","doi-asserted-by":"publisher","first-page":"1556","DOI":"10.1053\/j.gastro.2022.01.057","volume":"162","author":"R Baddeley","year":"2022","unstructured":"Baddeley R, Aabakken L, Veitch A, Hayee B (2022) Green endoscopy: counting the carbon cost of our practice. Gastroenterology 162(6):1556\u20131560","journal-title":"Gastroenterology"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-023-04493-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00384-023-04493-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-023-04493-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T11:30:40Z","timestamp":1703158240000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00384-023-04493-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,25]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["4493"],"URL":"https:\/\/doi.org\/10.1007\/s00384-023-04493-8","relation":{},"ISSN":["1432-1262"],"issn-type":[{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,25]]},"assertion":[{"value":"7 July 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Southern Adelaide Clinical Human Research Ethics Committee (SAC HREC), Adelaide, South Australia (HREC approval number 307.18), and was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. The study is registered with the Australian New Zealand Clinical Trials Registry (ANZCTR) valid from the 9th of December 2019 (Registration number ACTRN12619001743156).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approvals"}},{"value":"Flinders University reports grants and non-financial support from Eiken Chemical Co. Ltd. Eiken Chemical Co. Ltd. who did not have input on study design, data analysis, nor manuscript preparation.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"201"}}