{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:35:41Z","timestamp":1791848141896,"version":"4.3.4"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e0 degli Studi di Roma La Sapienza"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The objective of this study was to investigate predictive factors of mortality in emergency colorectal surgery in octogenarian patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>It is a retrospective cohort study conducted at a single-institution tertiary referral center. Consecutive patients who underwent emergency colorectal surgery between January 2015 and January 2020 were identified. The primary endpoint was 30-day mortality. Univariate and multivariate analyses were performed using a logistic regression model.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 111 patients were identified (43 men, 68 women). Mean age was 85.7\u2009\u00b1\u20093.7 years (80\u201396). Main diagnoses included complicated sigmoiditis in 38 patients (34.3%), cancer in 35 patients (31.5%), and ischemic colitis in 31 patients (27.9%). An ASA score of 3 or higher was observed in 88.3% of patients. The mean Charlson score was 5.9. The Possum score was 35.9% for mortality and 79.3% for morbidity. The 30-day mortality rate was 25.2%. Univariate analysis of preoperative risk factors for mortality shows that the history of valvular heart disease (p\u2009=\u20090.008), intensive care unit provenance (p\u2009=\u20090.003), preoperative sepsis (p\u2009&lt;\u20090.001), diagnosis of ischemic colitis (p\u2009=\u20090.012), creatinine (p\u2009=\u20090.006) and lactate levels (p\u2009=\u20090.01) were significantly associated with 30-day mortality, and patients coming from home had a lower 30-day mortality rate (p\u2009=\u20090.018). Intraoperative variables associated with 30-day mortality included ileostomy creation (p\u2009=\u20090.022) and temporary laparostomy (p\u2009=\u20090.004). At multivariate analysis, only lactate (p\u2009=\u20090.032) and creatinine levels (p\u2009=\u20090.027) were found to be independent predictors of 30-day mortality, home provenance was an independent protective factor (p\u2009=\u20090.004). Mean follow-up was 3.4 years. Survival at 1 and 3 years was 57.6 and 47.7%.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Emergency colorectal surgery is challenging. However, age should not be a contraindication. The 30-day mortality rate (25.2%) is one of the lowest in the literature. Hyperlactatemia (&gt;\u20092mmol\/L) and creatinine levels appear to be independent predictors of mortality.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00384-023-04565-9","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T15:03:18Z","timestamp":1700578998000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Risk factors for in-hospital mortality after emergency colorectal surgery in octogenarians: results of a cohort study from a referral center"],"prefix":"10.1007","volume":"38","author":[{"given":"Guillaume","family":"Mathis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Lapergola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Alexandre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Philouze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Mutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1880-4635","authenticated-orcid":false,"given":"Antonio","family":"D\u2019Urso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,21]]},"reference":[{"issue":"9696","key":"4565_CR1","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1016\/S0140-6736(09)61460-4","volume":"374","author":"K Christensen","year":"2009","unstructured":"Christensen K, Doblhammer G, Rau R, Vaupel JW (2009) Ageing populations: the challenges ahead. 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