{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T11:32:33Z","timestamp":1787139153637,"version":"build-2736575974"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>To evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A systematic search of multiple electronic data sources was conducted, and all studies comparing low with high (standard) intraabdominal pressures were included. Our primary outcomes were post-operative ileus occurrence and return of bowel movement\/flatus. The evaluated secondary outcomes included: total operative time, post-operative haemorrhage, anastomotic leak, pneumonia, surgical site infection, overall post-operative complications (categorised by Clavien-Dindo grading), and length of hospital stay. Revman 5.4 was used for data analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Six randomised controlled trials (RCTs) and one observational study with a total of 771 patients (370 surgery at low intraabdominal pressure and 401 at high pressures) were included. There was no statistically significant difference in all the measured outcomes; post-operative ileus [OR 0.80; CI (0.42, 1.52), <jats:italic>P<\/jats:italic>\u2009=\u20090.50], time-to-pass flatus [OR -4.31; CI (-12.12, 3.50), <jats:italic>P<\/jats:italic>\u2009=\u20090.28], total operative time [OR 0.40; CI (-10.19, 11.00), <jats:italic>P<\/jats:italic>\u2009=\u20090.94], post-operative haemorrhage [OR 1.51; CI (0.41, 5.58, <jats:italic>P<\/jats:italic>\u2009=\u20090.53], anastomotic leak [OR 1.14; CI (0.26, 4.91), P\u2009=\u20090.86], pneumonia [OR 1.15; CI (0.22, 6.09), P\u2009=\u20090.87], SSI [OR 0.69; CI (0.19, 2.47), <jats:italic>P<\/jats:italic>\u2009=\u20090.57], overall post-operative complications [OR 0.82; CI (0.52, 1.30), <jats:italic>P<\/jats:italic>\u2009=\u20090.40], Clavien-Dindo grade\u2009\u2265\u20093 [OR 1.27; CI (0.59, 2.77), <jats:italic>P<\/jats:italic>\u2009=\u20090.54], and length of hospital stay [OR -0.68; CI (-1.61, 0.24), <jats:italic>P<\/jats:italic>\u2009=\u20090.15].<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Low intraabdominal pressure is safe and feasible approach to laparoscopic colorectal resection surgery with non-inferior outcomes to standard or high pressures. More robust and well-powered RCTs are needed to consolidate the potential benefits of low over high pressure intra-abdominal surgery.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00384-024-04679-8","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T06:02:31Z","timestamp":1720591351000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of low versus high (standard) intraabdominal pressure during laparoscopic colorectal surgery: systematic review and meta-analysis"],"prefix":"10.1007","volume":"39","author":[{"given":"Mohammed","family":"Hamid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar E. 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