{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:06:54Z","timestamp":1767139614608,"version":"build-2238731810"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005609","name":"University of Turku","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005609","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Clinical scoring could help physicians identify patients with suspected acute diverticulitis who would benefit from further evaluation using computed tomography imaging. The aim of the study was to identify risk factors for complicated acute diverticulitis and create a risk score to predict disease severity in acute diverticulitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients diagnosed with CT-verified acute diverticulitis between 2015 and 2017 were included. Data on patients\u2019 clinical and laboratory findings and medical histories were collected retrospectively. Risk factors for complicated acute diverticulitis were identified using univariate and multivariate analyses. Continuous laboratory values were categorised by cut-off points determined using receiver operating characteristic (ROC) analysis. The Acute Diverticulitis Severity Score was formulated using logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the total 513 patients included in the study, 449 (88%) had UAD, and 64 (12%) had CAD. Older age, significant comorbidities, C-reactive protein level, leucocyte count, vomiting, and body temperature were found to be independently associated with a higher risk for CAD. The novel Acute Diverticulitis Severity Score could reliably detect patients with CAD. The area under the ROC curve was 0.856 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) in discriminating disease severity. While higher scores indicate radiological studies, patients with low scores face an almost non-existent risk for complicated disease, making such studies possibly redundant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Acute Diverticulitis Severity Score accurately separated patients with uncomplicated disease from those at risk for complicated disease. This score can be applied in daily clinical practice to select patients requiring further investigation, consequently reducing healthcare costs and burdens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00384-024-04740-6","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T10:52:20Z","timestamp":1728989540000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A novel scoring system for predicting disease severity without CT imaging in acute diverticulitis"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5105-088X","authenticated-orcid":false,"given":"Leena-Mari","family":"M\u00e4ntym\u00e4ki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9008-7116","authenticated-orcid":false,"given":"Juha","family":"Gr\u00f6nroos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1624-2253","authenticated-orcid":false,"given":"Jukka","family":"Karvonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3092-5245","authenticated-orcid":false,"given":"Mika","family":"Ukkonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"4740_CR1","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1080\/00365521.2022.2111225","volume":"58","author":"R Saren","year":"2023","unstructured":"Saren R, Aspegren S, Paajanen H, Ukkonen M, K\u00e4kel\u00e4 P (2023) Incidence of acute diverticulitis compared to appendicitis in emergency wards: a 10-year nationwide register and cohort study from Finland. Scand J Gastroenterol 58:151\u2013156. https:\/\/doi.org\/10.1080\/00365521.2022.2111225","journal-title":"Scand J Gastroenterol"},{"key":"4740_CR2","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1053\/j.gastro.2018.08.063","volume":"156","author":"AF Peery","year":"2019","unstructured":"Peery AF, Crockett SD, Murphy CC, Lund JL, Dellon ES, Williams JL, Jensen ET, Shaheen NJ, Barritt AS, Lieber SR, Kochar B, Barnes EL, Fan YC, Pate V, Galanko J, Baron TH, Sandler RS (2019) Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: update 2018. Gastroenterology 156:254-272.e11. https:\/\/doi.org\/10.1053\/j.gastro.2018.08.063","journal-title":"Gastroenterology"},{"key":"4740_CR3","doi-asserted-by":"publisher","unstructured":"Chabok A, P\u00e5hlman L, Hjern F, Haapaniemi S, Smedh K, AVOD study group (2012) randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg 99:532\u20139. https:\/\/doi.org\/10.1002\/bjs.8688","DOI":"10.1002\/bjs.8688"},{"key":"4740_CR4","doi-asserted-by":"publisher","unstructured":"Qaseem A, Etxeandia-Ikobaltzeta I, Lin JS, Fitterman N, Shamliyan T, Wilt TJ, Clinical Guidelines Committee of the American College of Physicians*, Crandall CJ, Cooney TG, Cross JT, Hicks LA, Maroto M, Mustafa RA, Obley AJ, Owens DK, Tice J, Williams JW, Clinical Guidelines Committee of the American College of Physicians (2022) Diagnosis and management of acute left-sided colonic diverticulitis: a clinical guideline from the American College of Physicians. Ann Intern Med 175:399\u2013415. https:\/\/doi.org\/10.7326\/M21-2710","DOI":"10.7326\/M21-2710"},{"key":"4740_CR5","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1007\/s00330-001-1143-y","volume":"12","author":"P Ambrosetti","year":"2002","unstructured":"Ambrosetti P, Becker C, Terrier F (2002) Colonic diverticulitis: impact of imaging on surgical management \u2013 a prospective study of 542 patients. Eur Radiol 12:1145\u20131149. https:\/\/doi.org\/10.1007\/s00330-001-1143-y","journal-title":"Eur Radiol"},{"key":"4740_CR6","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1016\/j.ajem.2015.07.082","volume":"33","author":"AN Barksdale","year":"2015","unstructured":"Barksdale AN, Hackman JL, Gaddis M, Gratton MC (2015) Diagnosis and disposition are changed when board-certified emergency physicians use CT for non-traumatic abdominal pain. Am J Emerg Med 33:1646\u20131650. https:\/\/doi.org\/10.1016\/j.ajem.2015.07.082","journal-title":"Am J Emerg Med"},{"key":"4740_CR7","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1007\/DCR.0b013e3181d98d86","volume":"53","author":"W Lam\u00e9ris","year":"2010","unstructured":"Lam\u00e9ris W, van Randen A, van Gulik TM, Busch ORC, Winkelhagen J, Bossuyt PMM, Stoker J, Boermeester MA (2010) A clinical decision rule to establish the diagnosis of acute diverticulitis at the emergency department. Dis Colon Rectum 53:896\u2013904. https:\/\/doi.org\/10.1007\/DCR.0b013e3181d98d86","journal-title":"Dis Colon Rectum"},{"key":"4740_CR8","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s13017-020-00313-4","volume":"15","author":"M Sartelli","year":"2020","unstructured":"Sartelli M, Weber DG, Kluger Y, Ansaloni L, Coccolini F, Abu-Zidan F, Augustin G, Ben-Ishay O, Biffl WL, Bouliaris K, Catena R, Ceresoli M, Chiara O, Chiarugi M, Coimbra R, Cortese F, Cui Y, Damaskos D, de Angelis GL, Delibegovic S, Demetrashvili Z, De Simone B, Di Marzo F, Di Saverio S, Duane TM, Faro MP, Fraga GP, Gkiokas G, Gomes CA, Hardcastle TC, Hecker A, Karamarkovic A, Kashuk J, Khokha V, Kirkpatrick AW, Kok KYY, Inaba K, Isik A, Labricciosa FM, Latifi R, Lepp\u00e4niemi A, Litvin A, Mazuski JE, Maier RV, Marwah S, McFarlane M, Moore EE, Moore FA, Negoi I, Pagani L, Rasa K, Rubio-Perez I, Sakakushev B, Sato N, Sganga G, Siquini W, Tarasconi A, Tolonen M, Ulrych J, Zachariah SK, Catena F (2020) 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg 15:32. https:\/\/doi.org\/10.1186\/s13017-020-00313-4","journal-title":"World J Emerg Surg"},{"issue":"Suppl 2","key":"4740_CR9","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/codi.15140","volume":"22","author":"JK Schultz","year":"2020","unstructured":"Schultz JK, Azhar N, Binda GA, Barbara G, Biondo S, Boermeester MA, Chabok A, Consten ECJ, van Dijk ST, Johanssen A, Kruis W, Lambrichts D, Post S, Ris F, Rockall TA, Samuelsson A, Di Saverio S, Tartaglia D, Thorisson A, Winter DC, Bemelman W, Angenete E (2020) European Society of coloproctology: guidelines for the management of diverticular disease of the colon. Colorectal Dis 22(Suppl 2):5\u201328. https:\/\/doi.org\/10.1111\/codi.15140","journal-title":"Colorectal Dis"},{"key":"4740_CR10","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1007\/s00384-017-2872-y","volume":"32","author":"HE Bolkenstein","year":"2017","unstructured":"Bolkenstein HE, van de Wall BJM, Consten ECJ, Broeders IAMJ, Draaisma WA (2017) Risk factors for complicated diverticulitis: systematic review and meta-analysis. Int J Colorectal Dis 32:1375\u20131383. https:\/\/doi.org\/10.1007\/s00384-017-2872-y","journal-title":"Int J Colorectal Dis"},{"key":"4740_CR11","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1080\/00365521.2018.1517188","volume":"53","author":"HE Bolkenstein","year":"2018","unstructured":"Bolkenstein HE, van de Wall BJ, Consten EC, van der Palen J, Broeders IA, Draaisma WA (2018) Development and validation of a diagnostic prediction model distinguishing complicated from uncomplicated diverticulitis. Scand J Gastroenterol 53:1291\u20131297. https:\/\/doi.org\/10.1080\/00365521.2018.1517188","journal-title":"Scand J Gastroenterol"},{"key":"4740_CR12","doi-asserted-by":"publisher","first-page":"80","DOI":"10.3390\/jpm11020080","volume":"11","author":"M Covino","year":"2021","unstructured":"Covino M, Papa V, Tursi A, Simeoni B, Lopetuso LR, Vetrone LM, Franceschi F, Rapaccini G, Gasbarrini A, Papa A (2021) Development and validation of predictive assessment of complicated diverticulitis score. J Pers Med 11:80. https:\/\/doi.org\/10.3390\/jpm11020080","journal-title":"J Pers Med"},{"key":"4740_CR13","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/1471-230X-14-114","volume":"14","author":"HE Sammalkorpi","year":"2014","unstructured":"Sammalkorpi HE, Mentula P, Lepp\u00e4niemi A (2014) A new adult appendicitis score improves diagnostic accuracy of acute appendicitis\u2013a prospective study. BMC Gastroenterol 14:114. https:\/\/doi.org\/10.1186\/1471-230X-14-114","journal-title":"BMC Gastroenterol"},{"key":"4740_CR14","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s13017-020-00306-3","volume":"15","author":"S di Saverio","year":"2020","unstructured":"di Saverio S, Podda M, de Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, de Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Lepp\u00e4niemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, de Angelis GL, Tan E, van Goor H, Pata F, di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F (2020) Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg 15:27. https:\/\/doi.org\/10.1186\/s13017-020-00306-3","journal-title":"World J Emerg Surg"},{"key":"4740_CR15","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1097\/TA.0000000000000540","volume":"78","author":"VJ Sallinen","year":"2015","unstructured":"Sallinen VJ, Lepp\u00e4niemi AK, Mentula PJ (2015) Staging of acute diverticulitis based on clinical, radiologic, and physiologic parameters. J Trauma Acute Care Surg 78:543\u2013551. https:\/\/doi.org\/10.1097\/TA.0000000000000540","journal-title":"J Trauma Acute Care Surg"},{"key":"4740_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejrad.2016.11.031","volume":"87","author":"TT Lehtim\u00e4ki","year":"2017","unstructured":"Lehtim\u00e4ki TT, Valtonen H, Miettinen P, Juvonen P, Paajanen H, Vanninen R (2017) A randomised clinical trial of routine versus selective CT imaging in acute abdomen: impact of patient age on treatment costs and hospital resource use. Eur J Radiol 87:1\u20137. https:\/\/doi.org\/10.1016\/j.ejrad.2016.11.031","journal-title":"Eur J Radiol"},{"key":"4740_CR17","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s13017-022-00408-0","volume":"17","author":"P Fugazzola","year":"2022","unstructured":"Fugazzola P, Ceresoli M, Coccolini F, Gabrielli F, Puzziello A, Monzani F, Amato B, Sganga G, Sartelli M, Menichetti F, Puglisi GA, Tartaglia D, Carcoforo P, Avenia N, Kluger Y, Paolillo C, Zago M, Lepp\u00e4niemi A, Tomasoni M, Cobianchi L, Dal Mas F, Improta M, Moore EE, Peitzman AB, Sugrue M, Agnoletti V, Fraga GP, Weber DG, Damaskos D, Abu-Zidan FM, Wani I, Kirkpatrick AW, Pikoulis M, Pararas N, Tan E, Ten BR, Maier RV, Davies RJ, Kashuk J, Shelat VG, Mefire AC, Augustin G, Magnone S, Poiasina E, De Simone B, Chiarugi M, Biffl W, Baiocchi GL, Catena F, Ansaloni L (2022) The WSES\/SICG\/ACOI\/SICUT\/AcEMC\/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly. World J Emerg Surg 17:5. https:\/\/doi.org\/10.1186\/s13017-022-00408-0","journal-title":"World J Emerg Surg"},{"key":"4740_CR18","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/s00384-015-2410-8","volume":"31","author":"JT M\u00e4kel\u00e4","year":"2016","unstructured":"M\u00e4kel\u00e4 JT, Klintrup K, Rautio T (2016) The role of low CRP values in the prediction of the development of acute diverticulitis. Int J Colorectal Dis 31:23\u201327. https:\/\/doi.org\/10.1007\/s00384-015-2410-8","journal-title":"Int J Colorectal Dis"},{"key":"4740_CR19","doi-asserted-by":"publisher","first-page":"536","DOI":"10.3109\/00365521.2014.999350","volume":"50","author":"JT M\u00e4kel\u00e4","year":"2015","unstructured":"M\u00e4kel\u00e4 JT, Klintrup K, Takala H, Rautio T (2015) The role of C-reactive protein in prediction of the severity of acute diverticulitis in an emergency unit. Scand J Gastroenterol 50:536\u2013541. https:\/\/doi.org\/10.3109\/00365521.2014.999350","journal-title":"Scand J Gastroenterol"},{"key":"4740_CR20","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/codi.12072","volume":"15","author":"BJM van de Wall","year":"2013","unstructured":"van de Wall BJM, Draaisma WA, van der Kaaij RT, Consten ECJ, Wiezer MJ, Broeders IAMJ (2013) The value of inflammation markers and body temperature in acute diverticulitis. Colorectal Dis 15:621\u2013626. https:\/\/doi.org\/10.1111\/codi.12072","journal-title":"Colorectal Dis"},{"key":"4740_CR21","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1111\/apt.12047","volume":"36","author":"GF Longstreth","year":"2012","unstructured":"Longstreth GF, Iyer RL, Chu L-HX, Chen W, Yen LS, Hodgkins P, Kawatkar AA (2012) Acute diverticulitis: demographic, clinical and laboratory features associated with computed tomography findings in 741 patients. Aliment Pharmacol Ther 36:886\u2013894. https:\/\/doi.org\/10.1111\/apt.12047","journal-title":"Aliment Pharmacol Ther"},{"key":"4740_CR22","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1097\/SLA.0b013e3182113614","volume":"253","author":"CS Andeweg","year":"2011","unstructured":"Andeweg CS, Knobben L, Hendriks JCM, Bleichrodt RP, van Goor H (2011) How to diagnose acute left-sided colonic diverticulitis. Ann Surg 253:940\u2013946. https:\/\/doi.org\/10.1097\/SLA.0b013e3182113614","journal-title":"Ann Surg"},{"key":"4740_CR23","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1080\/02841859809172202","volume":"39","author":"HB Eggesb\u00f8","year":"1998","unstructured":"Eggesb\u00f8 HB, Jacobsen T, Kolmannskog F, Bay D, Nygaard K (1998) Diagnosis of acute left-sided colonic diverticulitis by three radiological modalities. Acta Radiol 39:315\u2013321. https:\/\/doi.org\/10.1080\/02841859809172202","journal-title":"Acta Radiol"},{"key":"4740_CR24","doi-asserted-by":"publisher","unstructured":"Sigurdardottir J, Chabok A, Wagner P, Nikberg M (2022) Increased accuracy in diagnosing diverticulitis using predictive clinical factors. Ups J Med Sci 127:. https:\/\/doi.org\/10.48101\/ujms.v127.8803","DOI":"10.48101\/ujms.v127.8803"},{"key":"4740_CR25","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1749-7922-10-3","volume":"10","author":"M Sartelli","year":"2015","unstructured":"Sartelli M, Moore FA, Ansaloni L, Di Saverio S, Coccolini F, Griffiths EA, Coimbra R, Agresta F, Sakakushev B, Ordo\u00f1ez CA, Abu-Zidan FM, Karamarkovic A, Augustin G, Costa Navarro D, Ulrych J, Demetrashvili Z, Melo RB, Marwah S, Zachariah SK, Wani I, Shelat VG, Il KJ, McFarlane M, Pintar T, Rems M, Bala M, Ben-Ishay O, Gomes CA, Faro MP, Pereira GA, Catani M, Baiocchi G, Bini R, Anania G, Negoi I, Kecbaja Z, Omari AH, Cui Y, Kenig J, Sato N, Vereczkei A, Skrovina M, Das K, Bellanova G, Di Carlo I, Segovia Lohse HA, Kong V, Kok KY, Massalou D, Smirnov D, Gachabayov M, Gkiokas G, Marinis A, Spyropoulos C, Nikolopoulos I, Bouliaris K, Tepp J, Lohsiriwat V, \u00c7olak E, Isik A, Rios-Cruz D, Soto R, Abbas A, Tran\u00e0 C, Caproli E, Soldatenkova D, Corcione F, Piazza D, Catena F (2015) A proposal for a CT driven classification of left colon acute diverticulitis. World J Emerg Surg 10:3. https:\/\/doi.org\/10.1186\/1749-7922-10-3","journal-title":"World J Emerg Surg"},{"key":"4740_CR26","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1111\/j.1572-0241.2005.41154.x","volume":"100","author":"AM Kaiser","year":"2005","unstructured":"Kaiser AM, Jiang J-K, Lake JP, Ault G, Artinyan A, Gonzalez-Ruiz C, Essani R, Beart RW (2005) The management of complicated diverticulitis and the role of computed tomography. Am J Gastroenterol 100:910\u2013917. https:\/\/doi.org\/10.1111\/j.1572-0241.2005.41154.x","journal-title":"Am J Gastroenterol"},{"key":"4740_CR27","doi-asserted-by":"publisher","first-page":"4283","DOI":"10.1007\/s00068-022-01911-4","volume":"48","author":"JC Sebasti\u00e1n-Tom\u00e1s","year":"2022","unstructured":"Sebasti\u00e1n-Tom\u00e1s JC, G\u00f3mez-Abril SA, Ripoll\u00e9s T, Manrique A, Torres-Sanchez T, Mart\u00ednez-P\u00e9rez MJ (2022) How to strengthen the management of acute diverticulitis: the utility of the WSES classification-a prospective single-center observational study. Eur J Trauma Emerg Surg 48:4283\u20134291. https:\/\/doi.org\/10.1007\/s00068-022-01911-4","journal-title":"Eur J Trauma Emerg Surg"},{"key":"4740_CR28","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1007\/s00384-017-2847-z","volume":"32","author":"G-R Joliat","year":"2017","unstructured":"Joliat G-R, Emery J, Demartines N, H\u00fcbner M, Yersin B, Hahnloser D (2017) Antibiotic treatment for uncomplicated and mild complicated diverticulitis: outpatient treatment for everyone. Int J Colorectal Dis 32:1313\u20131319. https:\/\/doi.org\/10.1007\/s00384-017-2847-z","journal-title":"Int J Colorectal Dis"},{"key":"4740_CR29","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1007\/s11605-019-04153-9","volume":"23","author":"HE Bolkenstein","year":"2019","unstructured":"Bolkenstein HE, van Dijk ST, Consten ECJ, Heggelman BGF, Hoeks CMA, Broeders IAMJ, Boermeester MA, Draaisma WA (2019) Conservative treatment in diverticulitis patients with pericolic extraluminal air and the role of antibiotic treatment. J Gastrointest Surg 23:2269\u20132276. https:\/\/doi.org\/10.1007\/s11605-019-04153-9","journal-title":"J Gastrointest Surg"},{"key":"4740_CR30","doi-asserted-by":"publisher","first-page":"2538","DOI":"10.1007\/s00330-013-2848-4","volume":"23","author":"T Lehtim\u00e4ki","year":"2013","unstructured":"Lehtim\u00e4ki T, Juvonen P, Valtonen H, Miettinen P, Paajanen H, Vanninen R (2013) Impact of routine contrast-enhanced CT on costs and use of hospital resources in patients with acute abdomen. Results of a randomised clinical trial. Eur Radiol 23:2538\u20132545. https:\/\/doi.org\/10.1007\/s00330-013-2848-4","journal-title":"Eur Radiol"},{"key":"4740_CR31","doi-asserted-by":"publisher","first-page":"e34493","DOI":"10.7759\/cureus.34493","volume":"15","author":"A Fialho","year":"2023","unstructured":"Fialho A, Fialho A, Shuja A (2023) Analysis of the epidemiological trends on inpatient diverticulosis admissions in the US: a longitudinal analysis from 1997\u20132018. Cureus 15:e34493. https:\/\/doi.org\/10.7759\/cureus.34493","journal-title":"Cureus"},{"key":"4740_CR32","doi-asserted-by":"publisher","unstructured":"Daniels L, \u00dcnl\u00fc \u00c7, de Korte N, van Dieren S, Stockmann HB, Vrouenraets BC, Consten EC, van der Hoeven JA, Eijsbouts QA, Faneyte IF, Bemelman WA, Dijkgraaf MG, Boermeester MA, Dutch Diverticular Disease (3D) Collaborative Study Group (2017) Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. Br J Surg 104:52\u201361. https:\/\/doi.org\/10.1002\/bjs.10309","DOI":"10.1002\/bjs.10309"},{"key":"4740_CR33","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1097\/DCR.0000000000001330","volume":"62","author":"S Au","year":"2019","unstructured":"Au S, Aly EH (2019) Treatment of Uncomplicated acute diverticulitis without antibiotics: a systematic review and meta-analysis. Dis Colon Rectum 62:1533\u20131547. https:\/\/doi.org\/10.1097\/DCR.0000000000001330","journal-title":"Dis Colon Rectum"},{"key":"4740_CR34","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1097\/SLA.0b013e3182965a11","volume":"259","author":"S Biondo","year":"2014","unstructured":"Biondo S, Golda T, Kreisler E, Espin E, Vallribera F, Oteiza F, Codina-Cazador A, Pujadas M, Flor B (2014) Outpatient versus hospitalization management for uncomplicated diverticulitis. Ann Surg 259:38\u201344. https:\/\/doi.org\/10.1097\/SLA.0b013e3182965a11","journal-title":"Ann Surg"},{"key":"4740_CR35","doi-asserted-by":"publisher","first-page":"e557","DOI":"10.1097\/MD.0000000000000557","volume":"94","author":"V Sallinen","year":"2015","unstructured":"Sallinen V, Mali J, Lepp\u00e4niemi A, Mentula P (2015) Assessment of risk for recurrent diverticulitis: a proposal of risk score for complicated recurrence. Medicine 94:e557. https:\/\/doi.org\/10.1097\/MD.0000000000000557","journal-title":"Medicine"},{"key":"4740_CR36","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00384-023-04389-7","volume":"38","author":"CW Poh","year":"2023","unstructured":"Poh CW, Goh CK, Tan DJH, Chong CS (2023) Antibiotics vs observational therapy in acute uncomplicated diverticulitis, a systemic review and meta-analysis. Int J Colorectal Dis 38:97. https:\/\/doi.org\/10.1007\/s00384-023-04389-7","journal-title":"Int J Colorectal Dis"},{"key":"4740_CR37","doi-asserted-by":"publisher","unstructured":"Mora-L\u00f3pez L, Ruiz-Edo N, Estrada-Ferrer O, Pi\u00f1ana-Camp\u00f3n ML, Labr\u00f3-Ciurans M, Escuder-Perez J, Sales-Mallafr\u00e9 R, Rebasa-Cladera P, Navarro-Soto S, Serra-Aracil X, DINAMO-study Group (2021) Efficacy and safety of nonantibiotic outpatient treatment in mild acute diverticulitis (DINAMO-study): a multicentre, randomised, open-label, noninferiority trial. Ann Surg 274:e435\u2013e442. https:\/\/doi.org\/10.1097\/SLA.0000000000005031","DOI":"10.1097\/SLA.0000000000005031"}],"updated-by":[{"DOI":"10.1007\/s00384-024-04751-3","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000}}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-024-04740-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00384-024-04740-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-024-04740-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T14:03:42Z","timestamp":1736345022000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00384-024-04740-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,15]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4740"],"URL":"https:\/\/doi.org\/10.1007\/s00384-024-04740-6","relation":{},"ISSN":["1432-1262"],"issn-type":[{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,15]]},"assertion":[{"value":"10 October 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 October 2024","order":3,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":4,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":5,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00384-024-04751-3","URL":"https:\/\/doi.org\/10.1007\/s00384-024-04751-3","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the local ethics committee. The study was conducted according to the requirements of the Helsinki Declaration. In compliance with the principles of the local ethics committee, exemption from consent was obtained as the data had already been collected for clinical purposes.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"164"}}