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This study evaluates the impact of drain placement on perioperative outcomes using a propensity score-matched analysis in a single-center cohort.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Data from 185 patients who underwent minimally invasive right hemicolectomy with complete mesocolic excision and central vascular ligation at our institution from 2016 to November 2024 were analyzed, including 62 without drains and 123 with drains. After propensity score matching, 50 patients from each group were compared. Postoperative outcomes were assessed between the groups and multivariate analysis was performed to identify risk factors for postoperative morbidity.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Postoperative complications, including morbidity (18% vs. 24%, p\u2009=\u20090.624), anastomotic leakage (2% vs. 2%, p\u2009=\u20091.000), surgical site infections (4% vs. 4%, p\u2009=\u20091.000) and re-surgery rate (2% vs. 6%, p\u2009=\u20090.617), did not differ significantly. However, the drain group showed delayed recovery milestones: longer time to first stool (2.1 vs. 2.7\u00a0days, p\u2009=\u20090.041), completion of meal plan (4.0 vs. 4.3\u00a0days, p\u2009=\u20090.038) and prolonged hospital stay (7 vs. 8\u00a0days, p\u2009=\u20090.045). Enhanced recovery rates were higher in the no-drain group (48% vs. 28%; p\u2009=\u20090.039). Multivariate analysis identified preoperative hemoglobin level\u2009\u2264\u200913\u00a0g\/dl as a significant risk factor of postoperative complications (OR 9.8; 95% CI 2.0\u201348.7; p\u2009=\u20090.005), while drain placement was not significantly associated (p\u2009=\u20090.341).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>In minimally invasive right hemicolectomy with CME, routine drain placement does not reduce postoperative morbidity but may delay recovery milestones and prolong hospital stay. These findings suggest that selective rather than routine use of drains should be considered.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00384-025-04948-0","type":"journal-article","created":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T02:24:25Z","timestamp":1752287065000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The role of intraabdominal drain placement in minimal-invasive right hemicolectomy with complete mesocolic excision \u2013 a propensity score matched single center analysis"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9615-321X","authenticated-orcid":false,"given":"Maximilian","family":"Brunner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Bondartschuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3523-198X","authenticated-orcid":false,"given":"Axel","family":"Denz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg F.","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2559-0476","authenticated-orcid":false,"given":"Robert","family":"Gr\u00fctzmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2537-5824","authenticated-orcid":false,"given":"Christian","family":"Krautz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,12]]},"reference":[{"key":"4948_CR1","doi-asserted-by":"publisher","unstructured":"Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM, Heath RM, Brown JM, MRC CLASICC trial group (2005) Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. 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